DNA damage and oxidative stress induced by CeO2 nanoparticles in human dermal fibroblasts: Evidence of a clastogenic effect as a mechanism of genotoxicity

Nanotoxicology

Volumn 9, Issue 6, 2015, Pages 696-705

  Benameur, Laila ^a,b   Auffan, Mélanie ^c,d   Cassien, Mathieu ^a   Liu, Wei ^b,c   Culcasi, Marcel ^a   Rahmouni, Hidayat ^a   Stocker, Pierre ^a   Tassistro, Virginie ^b   Bottero, Jean Yves ^c,d   Rose, Jérôme ^c,d   Botta, Alain ^b,d   Pietri, Sylvia ^a  

^a AIX MARSEILLE UNIV   (France)

^b AVIGNON UNIVERSITÉ   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d International Consortium for the Environmental Implications of Nanotechnology ICEINT   (France)

Author keywords

Cytokinesis blocked micronucleus assay; free radicals; glutathione status; nanoceria; nanogenotoxicity

Indexed keywords

ACETYLCYSTEINE; CATALASE; CENTROMERE PROTEIN A; CERIUM OXIDE NANOPARTICLE; COLCHICINE; GLUTATHIONE; MITOMYCIN; CERIC OXIDE; CERIUM; COLLOID; MUTAGENIC AGENT; NANOPARTICLE;

ADSORPTION; ANAPHASE; ARTICLE; CELL PH; CELL PROLIFERATION; CHROMOSOME; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CONTROLLED STUDY; DNA DAMAGE; GENETIC TOXICOLOGY; GENOTOXICITY; HUMAN; HUMAN CELL; HYDRODYNAMICS; IMMUNOFLUORESCENCE; LIPID PEROXIDATION; MACRONUCLEUS; MICRONUCLEUS; MITOSIS; MTT ASSAY; NORMAL HUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SKIN FIBROBLAST; SURFACE CHARGE; SURFACE PROPERTY; ZETA POTENTIAL; CELL CULTURE; CHEMISTRY; COLLOID; DRUG EFFECTS; FIBROBLAST; METABOLISM; PARTICLE SIZE; PATHOLOGY; PRIMARY CELL CULTURE; SKIN;

CELLS, CULTURED; CERIUM; COLLOIDS; DNA DAMAGE; FIBROBLASTS; HUMANS; MUTAGENS; NANOPARTICLES; OXIDATIVE STRESS; PARTICLE SIZE; PRIMARY CELL CULTURE; SKIN; SURFACE PROPERTIES;

EID: 84925705979     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2014.968889     Document Type: Article

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