-
1
-
-
0036163156
-
Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese type II diabetic patients
-
COI: 1:CAS:528:DC%2BD38Xitl2js70%3D, PID: 11845227
-
Sakuraba H, Mizukami H, Yagihashi N, Wada R, Hanyu C, Yagihashi S (2002) Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese type II diabetic patients. Diabetologia 45:85–96
-
(2002)
Diabetologia
, vol.45
, pp. 85-96
-
-
Sakuraba, H.1
Mizukami, H.2
Yagihashi, N.3
Wada, R.4
Hanyu, C.5
Yagihashi, S.6
-
2
-
-
53549093011
-
Pancreatic β-cell mass in European subjects with type 2 diabetes
-
PID: 18834431
-
Rahier J, Guiot Y, Goebbels RM, Sempoux C, Henquin JC (2008) Pancreatic β-cell mass in European subjects with type 2 diabetes. Diabetes Obes Metab 10(Suppl 4):32–42
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 32-42
-
-
Rahier, J.1
Guiot, Y.2
Goebbels, R.M.3
Sempoux, C.4
Henquin, J.C.5
-
3
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
COI: 1:CAS:528:DC%2BD3sXisVaisA%3D%3D, PID: 12502499
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC (2003) β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 52:102–110
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
4
-
-
0035432491
-
Glucose induces β-cell apoptosis via upregulation of the Fas receptor in human islets
-
COI: 1:CAS:528:DC%2BD3MXlslKntbY%3D, PID: 11473025
-
Maedler K, Spinas GA, Lehmann R et al (2001) Glucose induces β-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes 50:1683–1690
-
(2001)
Diabetes
, vol.50
, pp. 1683-1690
-
-
Maedler, K.1
Spinas, G.A.2
Lehmann, R.3
-
5
-
-
33947305767
-
Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose
-
COI: 1:CAS:528:DC%2BD2sXktlOltrk%3D
-
DelGuerra S, Grupillo M, Masini M et al (2007) Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose. Diabetes Metab Res Rev 23:234–238
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 234-238
-
-
DelGuerra, S.1
Grupillo, M.2
Masini, M.3
-
6
-
-
59449084679
-
Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations
-
COI: 1:CAS:528:DC%2BD1MXhtlKisL0%3D, PID: 19165461
-
Bensellam M, van Lommel L, Overbergh L, Schuit FC, Jonas JC (2009) Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations. Diabetologia 52:463–476
-
(2009)
Diabetologia
, vol.52
, pp. 463-476
-
-
Bensellam, M.1
van Lommel, L.2
Overbergh, L.3
Schuit, F.C.4
Jonas, J.C.5
-
7
-
-
70350310991
-
Glucose regulation of islet stress responses and β-cell failure in type 2 diabetes
-
COI: 1:CAS:528:DC%2BD1MXhsVOlsbzJ, PID: 19817790
-
Jonas JC, Bensellam M, Duprez J, Elouil H, Guiot Y, Pascal SM (2009) Glucose regulation of islet stress responses and β-cell failure in type 2 diabetes. Diabetes Obes Metab 11(Suppl 4):65–81
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 65-81
-
-
Jonas, J.C.1
Bensellam, M.2
Duprez, J.3
Elouil, H.4
Guiot, Y.5
Pascal, S.M.6
-
8
-
-
84897456888
-
The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity
-
COI: 1:CAS:528:DC%2BC2cXktV2msLg%3D, PID: 24625983
-
Wali JA, Rondas D, McKenzie MD et al (2014) The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity. Cell Death Dis 5:e1124
-
(2014)
Cell Death Dis
, vol.5
, pp. 1124
-
-
Wali, J.A.1
Rondas, D.2
McKenzie, M.D.3
-
9
-
-
0033034807
-
Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
-
COI: 1:CAS:528:DyaK1MXitFCqt7w%3D, PID: 10102689
-
Donath MY, Gross DJ, Cerasi E, Kaiser N (1999) Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 48:738–744
-
(1999)
Diabetes
, vol.48
, pp. 738-744
-
-
Donath, M.Y.1
Gross, D.J.2
Cerasi, E.3
Kaiser, N.4
-
10
-
-
55849096988
-
Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes
-
COI: 1:CAS:528:DC%2BD1cXht1ChsrvM, PID: 18776938
-
Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ (2008) Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes. J Clin Invest 118:3378–3389
-
(2008)
J Clin Invest
, vol.118
, pp. 3378-3389
-
-
Song, B.1
Scheuner, D.2
Ron, D.3
Pennathur, S.4
Kaufman, R.J.5
-
11
-
-
79953735981
-
Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure
-
COI: 1:CAS:528:DC%2BC3MXhsFKjtL4%3D, PID: 21107520
-
Kluth O, Mirhashemi F, Scherneck S et al (2011) Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure. Diabetologia 54:605–616
-
(2011)
Diabetologia
, vol.54
, pp. 605-616
-
-
Kluth, O.1
Mirhashemi, F.2
Scherneck, S.3
-
12
-
-
33745234081
-
Diabetes, glucose toxicity, and oxidative stress: a case of double jeopardy for the pancreatic islet β cell
-
COI: 1:CAS:528:DC%2BD28Xmt1OrsLw%3D, PID: 16814095
-
Robertson RP, Harmon JS (2006) Diabetes, glucose toxicity, and oxidative stress: a case of double jeopardy for the pancreatic islet β cell. Free Radic Biol Med 41:177–184
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 177-184
-
-
Robertson, R.P.1
Harmon, J.S.2
-
13
-
-
84867507940
-
The molecular mechanisms of pancreatic beta-cell glucotoxicity: recent findings and future research directions
-
COI: 1:CAS:528:DC%2BC38XhtlCjt7fM, PID: 22885162
-
Bensellam M, Laybutt DR, Jonas JC (2012) The molecular mechanisms of pancreatic beta-cell glucotoxicity: recent findings and future research directions. Mol Cell Endocrinol 364:1–27
-
(2012)
Mol Cell Endocrinol
, vol.364
, pp. 1-27
-
-
Bensellam, M.1
Laybutt, D.R.2
Jonas, J.C.3
-
14
-
-
0037125997
-
A role for glutathione peroxidase in protecting pancreatic β cells against oxidative stress in a model of glucose toxicity
-
COI: 1:CAS:528:DC%2BD38XntlCksb0%3D, PID: 12218186
-
Tanaka Y, Tran PO, Harmon J, Robertson RP (2002) A role for glutathione peroxidase in protecting pancreatic β cells against oxidative stress in a model of glucose toxicity. Proc Natl Acad Sci U S A 99:12363–12368
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12363-12368
-
-
Tanaka, Y.1
Tran, P.O.2
Harmon, J.3
Robertson, R.P.4
-
15
-
-
0037984371
-
Visualizing superoxide production in normal and diabetic rat islets of Langerhans
-
COI: 1:CAS:528:DC%2BD3sXhvV2hs78%3D, PID: 12514170
-
Bindokas VP, Kuznetsov A, Sreenan S, Polonsky KS, Roe MW, Philipson LH (2003) Visualizing superoxide production in normal and diabetic rat islets of Langerhans. J Biol Chem 278:9796–9801
-
(2003)
J Biol Chem
, vol.278
, pp. 9796-9801
-
-
Bindokas, V.P.1
Kuznetsov, A.2
Sreenan, S.3
Polonsky, K.S.4
Roe, M.W.5
Philipson, L.H.6
-
16
-
-
0037228626
-
Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic β-cells
-
COI: 1:CAS:528:DC%2BD38Xps1WgsLk%3D, PID: 12480546
-
Sakai K, Matsumoto K, Nishikawa T et al (2003) Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic β-cells. Biochem Biophys Res Commun 300:216–222
-
(2003)
Biochem Biophys Res Commun
, vol.300
, pp. 216-222
-
-
Sakai, K.1
Matsumoto, K.2
Nishikawa, T.3
-
17
-
-
0032998220
-
Hyperglycemia causes oxidative stress in pancreatic β-cells of GK rats, a model of type 2 diabetes
-
COI: 1:CAS:528:DyaK1MXitFCqtbc%3D, PID: 10102716
-
Ihara Y, Toyokuni S, Uchida K et al (1999) Hyperglycemia causes oxidative stress in pancreatic β-cells of GK rats, a model of type 2 diabetes. Diabetes 48:927–932
-
(1999)
Diabetes
, vol.48
, pp. 927-932
-
-
Ihara, Y.1
Toyokuni, S.2
Uchida, K.3
-
18
-
-
0036235710
-
Probucol preserves pancreatic β-cell function through reduction of oxidative stress in type 2 diabetes
-
COI: 1:CAS:528:DC%2BD38Xjtl2itLs%3D, PID: 12007724
-
Gorogawa S, Kajimoto Y, Umayahara Y et al (2002) Probucol preserves pancreatic β-cell function through reduction of oxidative stress in type 2 diabetes. Diabetes Res Clin Pract 57:1–10
-
(2002)
Diabetes Res Clin Pract
, vol.57
, pp. 1-10
-
-
Gorogawa, S.1
Kajimoto, Y.2
Umayahara, Y.3
-
19
-
-
77449154126
-
Molecular and metabolic evidence for mitochondrial defects associated with β-cell dysfunction in a mouse model of type 2 diabetes
-
COI: 1:CAS:528:DC%2BC3cXhvVyru7s%3D, PID: 19903739
-
Lu H, Koshkin V, Allister EM, Gyulkhandanyan AV, Wheeler MB (2010) Molecular and metabolic evidence for mitochondrial defects associated with β-cell dysfunction in a mouse model of type 2 diabetes. Diabetes 59:448–459
-
(2010)
Diabetes
, vol.59
, pp. 448-459
-
-
Lu, H.1
Koshkin, V.2
Allister, E.M.3
Gyulkhandanyan, A.V.4
Wheeler, M.B.5
-
20
-
-
0029984682
-
Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
-
COI: 1:CAS:528:DyaK28XhvVWitLw%3D, PID: 8720919
-
Lenzen S, Drinkgern J, Tiedge M (1996) Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic Biol Med 20:463–466
-
(1996)
Free Radic Biol Med
, vol.20
, pp. 463-466
-
-
Lenzen, S.1
Drinkgern, J.2
Tiedge, M.3
-
21
-
-
0036061635
-
Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to β-cell survival during chronic hyperglycemia
-
COI: 1:CAS:528:DC%2BD38XhtVaqu7w%3D, PID: 11812749
-
Laybutt DR, Kaneto H, Hasenkamp W et al (2002) Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to β-cell survival during chronic hyperglycemia. Diabetes 51:413–423
-
(2002)
Diabetes
, vol.51
, pp. 413-423
-
-
Laybutt, D.R.1
Kaneto, H.2
Hasenkamp, W.3
-
22
-
-
68349131414
-
Diabetic β-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses
-
PID: 19654863
-
Lacraz G, Figeac F, Movassat J et al (2009) Diabetic β-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses. PLoS ONE 4:e6500
-
(2009)
PLoS ONE
, vol.4
, pp. 6500
-
-
Lacraz, G.1
Figeac, F.2
Movassat, J.3
-
23
-
-
84893132156
-
Nrf2 protects pancreatic beta-cells from oxidative and nitrosative stress in diabetic model mice
-
COI: 1:CAS:528:DC%2BC2cXhvVSrs70%3D, PID: 24186865
-
Yagishita Y, Fukutomi T, Sugawara A et al (2014) Nrf2 protects pancreatic beta-cells from oxidative and nitrosative stress in diabetic model mice. Diabetes 63:605–618
-
(2014)
Diabetes
, vol.63
, pp. 605-618
-
-
Yagishita, Y.1
Fukutomi, T.2
Sugawara, A.3
-
24
-
-
24344479164
-
Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes
-
COI: 1:CAS:528:DC%2BD2MXhtVWisLzJ, PID: 16135796
-
Katsuoka F, Motohashi H, Ishii T, Aburatani H, Engel JD, Yamamoto M (2005) Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes. Mol Cell Biol 25:8044–8051
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8044-8051
-
-
Katsuoka, F.1
Motohashi, H.2
Ishii, T.3
Aburatani, H.4
Engel, J.D.5
Yamamoto, M.6
-
25
-
-
84869076474
-
Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks
-
COI: 1:CAS:528:DC%2BC38Xhs1Wqtr7L, PID: 22965115
-
Hirotsu Y, Katsuoka F, Funayama R et al (2012) Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks. Nucleic Acids Res 40:10228–10239
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 10228-10239
-
-
Hirotsu, Y.1
Katsuoka, F.2
Funayama, R.3
-
26
-
-
84889583650
-
Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis
-
COI: 1:CAS:528:DC%2BC3sXhsl2hu7jM, PID: 24232097
-
Tanigawa S, Lee CH, Lin CS et al (2013) Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis. Cell Death Dis 4:e921
-
(2013)
Cell Death Dis
, vol.4
, pp. 921
-
-
Tanigawa, S.1
Lee, C.H.2
Lin, C.S.3
-
27
-
-
0042347689
-
Id proteins in development, cell cycle and cancer
-
COI: 1:CAS:528:DC%2BD3sXlvVKis7w%3D, PID: 12888293
-
Ruzinova MB, Benezra R (2003) Id proteins in development, cell cycle and cancer. Trends Cell Biol 13:410–418
-
(2003)
Trends Cell Biol
, vol.13
, pp. 410-418
-
-
Ruzinova, M.B.1
Benezra, R.2
-
28
-
-
84905496932
-
ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities
-
COI: 1:CAS:528:DC%2BC2cXpsVKjtrk%3D, PID: 24827908
-
Nair R, Teo WS, Mittal V, Swarbrick A (2014) ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities. Mol Ther 22:1407–1415
-
(2014)
Mol Ther
, vol.22
, pp. 1407-1415
-
-
Nair, R.1
Teo, W.S.2
Mittal, V.3
Swarbrick, A.4
-
29
-
-
0034705104
-
Expression profiling of pancreatic β cells: glucose regulation of secretory and metabolic pathway genes
-
COI: 1:CAS:528:DC%2BD3cXjvFakt7s%3D, PID: 10811900
-
Webb GC, Akbar MS, Zhao C, Steiner DF (2000) Expression profiling of pancreatic β cells: glucose regulation of secretory and metabolic pathway genes. Proc Natl Acad Sci U S A 97:5773–5778
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5773-5778
-
-
Webb, G.C.1
Akbar, M.S.2
Zhao, C.3
Steiner, D.F.4
-
30
-
-
0035054637
-
Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells
-
COI: 1:CAS:528:DC%2BD3MXit1Gitb0%3D, PID: 11357476
-
Wice BM, Bernal-Mizrachi E, Permutt MA (2001) Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells. Diabetologia 44:453–463
-
(2001)
Diabetologia
, vol.44
, pp. 453-463
-
-
Wice, B.M.1
Bernal-Mizrachi, E.2
Permutt, M.A.3
-
31
-
-
24144496798
-
Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes
-
COI: 1:CAS:528:DC%2BD2MXhtVSjs7jO, PID: 16123366
-
Kjorholt C, Akerfeldt MC, Biden TJ, Laybutt DR (2005) Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes. Diabetes 54:2755–2763
-
(2005)
Diabetes
, vol.54
, pp. 2755-2763
-
-
Kjorholt, C.1
Akerfeldt, M.C.2
Biden, T.J.3
Laybutt, D.R.4
-
32
-
-
80053430193
-
Inhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance
-
COI: 1:CAS:528:DC%2BC3MXhtl2is7zP, PID: 21940780
-
Akerfeldt MC, Laybutt DR (2011) Inhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance. Diabetes 60:2506–2514
-
(2011)
Diabetes
, vol.60
, pp. 2506-2514
-
-
Akerfeldt, M.C.1
Laybutt, D.R.2
-
33
-
-
84876565085
-
Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in beta-cell gene expression and progression to diabetes
-
COI: 1:CAS:528:DC%2BC3sXhtVSnurbM, PID: 23274897
-
Chan JY, Luzuriaga J, Bensellam M, Biden TJ, Laybutt DR (2013) Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in beta-cell gene expression and progression to diabetes. Diabetes 62:1557–1568
-
(2013)
Diabetes
, vol.62
, pp. 1557-1568
-
-
Chan, J.Y.1
Luzuriaga, J.2
Bensellam, M.3
Biden, T.J.4
Laybutt, D.R.5
-
34
-
-
84887866253
-
Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle
-
COI: 1:CAS:528:DC%2BC3sXhslKqurjP, PID: 24078708
-
Montgomery MK, Osborne B, Brown SH et al (2013) Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle. J Lipid Res 54:3322–3333
-
(2013)
J Lipid Res
, vol.54
, pp. 3322-3333
-
-
Montgomery, M.K.1
Osborne, B.2
Brown, S.H.3
-
35
-
-
84855303456
-
2 consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells
-
COI: 1:CAS:528:DC%2BC38XptFOjsQ%3D%3D, PID: 22235342
-
2 consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells. PLoS ONE 7:e29807
-
(2012)
PLoS ONE
, vol.7
, pp. 29807
-
-
Bensellam, M.1
Duvillie, B.2
Rybachuk, G.3
-
36
-
-
0030456403
-
Reducing sugars trigger oxidative modification and apoptosis in pancreatic β-cells by provoking oxidative stress through the glycation reaction
-
COI: 1:CAS:528:DyaK2sXis1yiug%3D%3D, PID: 9003372
-
Kaneto H, Fujii J, Myint T et al (1996) Reducing sugars trigger oxidative modification and apoptosis in pancreatic β-cells by provoking oxidative stress through the glycation reaction. Biochem J 320(Pt 3):855–863
-
(1996)
Biochem J
, vol.320
, pp. 855-863
-
-
Kaneto, H.1
Fujii, J.2
Myint, T.3
-
37
-
-
0035877643
-
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
-
COI: 1:CAS:528:DC%2BD3MXksFGlsrc%3D, PID: 11274184
-
He CH, Gong P, Hu B et al (2001) Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem 276:20858–20865
-
(2001)
J Biol Chem
, vol.276
, pp. 20858-20865
-
-
He, C.H.1
Gong, P.2
Hu, B.3
-
38
-
-
0037595546
-
Comprehensive identification of human bZIP interactions with coiled-coil arrays
-
COI: 1:CAS:528:DC%2BD3sXkvVOrtr4%3D, PID: 12805554
-
Newman JR, Keating AE (2003) Comprehensive identification of human bZIP interactions with coiled-coil arrays. Science 300:2097–2101
-
(2003)
Science
, vol.300
, pp. 2097-2101
-
-
Newman, J.R.1
Keating, A.E.2
-
39
-
-
1942455887
-
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
-
COI: 1:CAS:528:DC%2BD2cXjsVelsL8%3D, PID: 15110385
-
Itoh K, Tong KI, Yamamoto M (2004) Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic Biol Med 36:1208–1213
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 1208-1213
-
-
Itoh, K.1
Tong, K.I.2
Yamamoto, M.3
-
40
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
COI: 1:CAS:528:DyaK2sXkvVWns78%3D, PID: 9240432
-
Itoh K, Chiba T, Takahashi S et al (1997) An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236:313–322
-
(1997)
Biochem Biophys Res Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
-
41
-
-
84880682182
-
The Keap1-Nrf2 system prevents onset of diabetes mellitus
-
COI: 1:CAS:528:DC%2BC3sXht1arur7J, PID: 23716596
-
Uruno A, Furusawa Y, Yagishita Y et al (2013) The Keap1-Nrf2 system prevents onset of diabetes mellitus. Mol Cell Biol 33:2996–3010
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2996-3010
-
-
Uruno, A.1
Furusawa, Y.2
Yagishita, Y.3
-
42
-
-
69949132408
-
Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction
-
COI: 1:CAS:528:DC%2BD1MXhtVWqt7%2FK, PID: 19546218
-
Li N, Brun T, Cnop M, Cunha DA, Eizirik DL, Maechler P (2009) Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction. J Biol Chem 284:23602–23612
-
(2009)
J Biol Chem
, vol.284
, pp. 23602-23612
-
-
Li, N.1
Brun, T.2
Cnop, M.3
Cunha, D.A.4
Eizirik, D.L.5
Maechler, P.6
-
43
-
-
20144364947
-
Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells
-
COI: 1:CAS:528:DC%2BD2MXktlCmu7w%3D, PID: 15774474
-
Martens GA, Cai Y, Hinke S, Stange G, van de Casteele M, Pipeleers D (2005) Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells. J Biol Chem 280:20389–20396
-
(2005)
J Biol Chem
, vol.280
, pp. 20389-20396
-
-
Martens, G.A.1
Cai, Y.2
Hinke, S.3
Stange, G.4
van de Casteele, M.5
Pipeleers, D.6
-
44
-
-
84866405516
-
Mitochondrial oxidative stress contributes differently to rat pancreatic islet cell apoptosis and insulin secretory defects after prolonged culture in a low non-stimulating glucose concentration
-
COI: 1:CAS:528:DC%2BC38XhtVWjt73J, PID: 22643931
-
Roma LP, Pascal SM, Duprez J, Jonas JC (2012) Mitochondrial oxidative stress contributes differently to rat pancreatic islet cell apoptosis and insulin secretory defects after prolonged culture in a low non-stimulating glucose concentration. Diabetologia 55:2226–2237
-
(2012)
Diabetologia
, vol.55
, pp. 2226-2237
-
-
Roma, L.P.1
Pascal, S.M.2
Duprez, J.3
Jonas, J.C.4
-
45
-
-
20244376316
-
Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients
-
COI: 1:CAS:528:DC%2BD2MXhvF2rurw%3D, PID: 15654602
-
Anello M, Lupi R, Spampinato D et al (2005) Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients. Diabetologia 48:282–289
-
(2005)
Diabetologia
, vol.48
, pp. 282-289
-
-
Anello, M.1
Lupi, R.2
Spampinato, D.3
-
46
-
-
70349650451
-
Mitochondrial networking protects beta-cells from nutrient-induced apoptosis
-
COI: 1:CAS:528:DC%2BD1MXht1yku7bE, PID: 19581419
-
Molina AJ, Wikstrom JD, Stiles L et al (2009) Mitochondrial networking protects beta-cells from nutrient-induced apoptosis. Diabetes 58:2303–2315
-
(2009)
Diabetes
, vol.58
, pp. 2303-2315
-
-
Molina, A.J.1
Wikstrom, J.D.2
Stiles, L.3
-
47
-
-
77953809309
-
4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes
-
COI: 1:CAS:528:DC%2BC3cXnvV2qsro%3D, PID: 20144584
-
Dlaskova A, Spacek T, Santorova J et al (2010) 4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes. Biochim Biophys Acta 1797:1327–1341
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 1327-1341
-
-
Dlaskova, A.1
Spacek, T.2
Santorova, J.3
-
48
-
-
33847256507
-
BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion
-
COI: 1:CAS:528:DC%2BD2sXjsF2qtLo%3D, PID: 17339028
-
Goulley J, Dahl U, Baeza N, Mishina Y, Edlund H (2007) BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion. Cell Metab 5:207–219
-
(2007)
Cell Metab
, vol.5
, pp. 207-219
-
-
Goulley, J.1
Dahl, U.2
Baeza, N.3
Mishina, Y.4
Edlund, H.5
-
49
-
-
70349167300
-
Abnormal glucose metabolism in heterozygous mutant mice for a type I receptor required for BMP signaling
-
COI: 1:CAS:528:DC%2BD1MXoslOlu7k%3D, PID: 19358156
-
Scott GJ, Ray MK, Ward T et al (2009) Abnormal glucose metabolism in heterozygous mutant mice for a type I receptor required for BMP signaling. Genesis 47:385–391
-
(2009)
Genesis
, vol.47
, pp. 385-391
-
-
Scott, G.J.1
Ray, M.K.2
Ward, T.3
-
50
-
-
79960395598
-
Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation
-
COI: 1:CAS:528:DC%2BC3MXovFCktLk%3D, PID: 21628466
-
Bonner C, Farrelly AM, Concannon CG et al (2011) Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation. J Biol Chem 286:25719–25728
-
(2011)
J Biol Chem
, vol.286
, pp. 25719-25728
-
-
Bonner, C.1
Farrelly, A.M.2
Concannon, C.G.3
|