-
1
-
-
77956018353
-
Revisiting the rosiglitazone story-lessons learned
-
Rosen CJ. Revisiting the rosiglitazone story-lessons learned. N Engl J Med. 2010; 363: 803-806.
-
(2010)
N Engl J Med
, vol.363
, pp. 803-806
-
-
Rosen, C.J.1
-
2
-
-
77953638099
-
Critics press FDA to act on evidence of rosiglitazone's cardiac safety issues
-
Mitka M. Critics press FDA to act on evidence of rosiglitazone's cardiac safety issues. JAMA. 2010; 303: 2341-2342.
-
(2010)
JAMA
, vol.303
, pp. 2341-2342
-
-
Mitka, M.1
-
3
-
-
77957952617
-
Regulatory action on rosiglitazone by the U.S. Food and Drug Administration
-
Woodcock J SJ, Hamburg M. Regulatory action on rosiglitazone by the U.S. Food and Drug Administration. N Eng J Med. 2010; 363: 1489-1491.
-
(2010)
N Eng J Med
, vol.363
, pp. 1489-1491
-
-
Woodcock J, S.J.1
Hamburg, M.2
-
4
-
-
54349120809
-
Cardiotoxic drugs: clinical monitoring and decision making
-
Wu AH. Cardiotoxic drugs: clinical monitoring and decision making. Heart. 2008; 94: 1503-1509.
-
(2008)
Heart
, vol.94
, pp. 1503-1509
-
-
Wu, A.H.1
-
5
-
-
33845596500
-
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
-
Handschin C, Spiegelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr Rev. 2006; 27: 728-735.
-
(2006)
Endocr Rev
, vol.27
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
6
-
-
12144286554
-
Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner
-
Russell LK, Mansfield CM, Lehman JJ, et al. Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner. Circ Res. 2004; 94: 525-533.
-
(2004)
Circ Res
, vol.94
, pp. 525-533
-
-
Russell, L.K.1
Mansfield, C.M.2
Lehman, J.J.3
-
7
-
-
70350137062
-
Diverse effects in Friedreich's ataxia place PGC-1alpha center-stage
-
Metzler M. Diverse effects in Friedreich's ataxia place PGC-1alpha center-stage. Clin Genet. 2009; 76: 345-347.
-
(2009)
Clin Genet
, vol.76
, pp. 345-347
-
-
Metzler, M.1
-
8
-
-
77956318471
-
PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia
-
Marmolino D, Manto M, Acquaviva F, et al. PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia. PLoS One. 2010; 5: e10025.
-
(2010)
PLoS One
, vol.5
-
-
Marmolino, D.1
Manto, M.2
Acquaviva, F.3
-
9
-
-
13344270899
-
Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion
-
Campuzano V, Montermini L, Molto MD, et al. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science. 1996; 271: 1423-1427.
-
(1996)
Science
, vol.271
, pp. 1423-1427
-
-
Campuzano, V.1
Montermini, L.2
Molto, M.D.3
-
10
-
-
0029821176
-
Clinical and genetic abnormalities in patients with Friedreich's ataxia
-
Durr A, Cossee M, Agid Y, et al. Clinical and genetic abnormalities in patients with Friedreich's ataxia. N Engl J Med. 1996; 335: 1169-1175.
-
(1996)
N Engl J Med
, vol.335
, pp. 1169-1175
-
-
Durr, A.1
Cossee, M.2
Agid, Y.3
-
11
-
-
0022560674
-
Cardiac involvement in Friedreich's ataxia: a clinical study of 75 patients
-
Child JS, Perloff JK, Bach PM, Wolfe AD, Perlman S, Kark RA. Cardiac involvement in Friedreich's ataxia: a clinical study of 75 patients. J Am Coll Cardiol. 1986; 7: 1370-1378.
-
(1986)
J Am Coll Cardiol
, vol.7
, pp. 1370-1378
-
-
Child, J.S.1
Perloff, J.K.2
Bach, P.M.3
Wolfe, A.D.4
Perlman, S.5
Kark, R.A.6
-
12
-
-
67949124861
-
PPAR-gamma agonist Azelaoyl PAF increases frataxin protein and mRNA expression: new implications for the Friedreich's ataxia therapy
-
Marmolino D, Acquaviva F, Pinelli M, et al. PPAR-gamma agonist Azelaoyl PAF increases frataxin protein and mRNA expression: new implications for the Friedreich's ataxia therapy. Cerebellum. 2009; 8: 98-103.
-
(2009)
Cerebellum
, vol.8
, pp. 98-103
-
-
Marmolino, D.1
Acquaviva, F.2
Pinelli, M.3
-
13
-
-
67249133451
-
Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia
-
Coppola G, Marmolino D, Lu D, et al. Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia. Hum Mol Genet. 2009; 18: 2452-2461.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 2452-2461
-
-
Coppola, G.1
Marmolino, D.2
Lu, D.3
-
15
-
-
34648835197
-
Ensuring drug safety: lessons from the thiazolidinediones
-
Ensuring drug safety: lessons from the thiazolidinediones. Lancet. 2007; 370: 1101.
-
(2007)
Lancet
, vol.370
, pp. 1101
-
-
-
16
-
-
41649092951
-
Effect of aspirin use on thiazolidinediones and cardiovascular events
-
author reply 1539-1540.
-
Konstantinopoulos PA, Karamouzis MV, Papavassiliou AG. Effect of aspirin use on thiazolidinediones and cardiovascular events. JAMA. 2008; 299: 1539; author reply 1539-1540.
-
(2008)
JAMA
, vol.299
, pp. 1539
-
-
Konstantinopoulos, P.A.1
Karamouzis, M.V.2
Papavassiliou, A.G.3
-
17
-
-
78650024521
-
Movement disorders: new insights into Parkinson's disease
-
Stoessl AJ. Movement disorders: new insights into Parkinson's disease. Lancet Neurol. 2011; 10: 5-7.
-
(2011)
Lancet Neurol
, vol.10
, pp. 5-7
-
-
Stoessl, A.J.1
-
18
-
-
54449092109
-
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease
-
Quintanilla RA, Jin YN, Fuenzalida K, Bronfman M, Johnson GV. Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease. J Biol Chem. 2008; 283: 25628-25637.
-
(2008)
J Biol Chem
, vol.283
, pp. 25628-25637
-
-
Quintanilla, R.A.1
Jin, Y.N.2
Fuenzalida, K.3
Bronfman, M.4
Johnson, G.V.5
-
19
-
-
78651322583
-
A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease
-
Geldmacher DS, Fritsch T, McClendon MJ, Landreth G. A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease. Arch Neurol. 2011; 68: 45-50.
-
(2011)
Arch Neurol
, vol.68
, pp. 45-50
-
-
Geldmacher, D.S.1
Fritsch, T.2
McClendon, M.J.3
Landreth, G.4
|