P-glycoprotein interactions of novel psychoactive substances - Stimulation of ATP consumption and transport across Caco-2 monolayers

Biochemical Pharmacology

Volumn 94, Issue 3, 2015, Pages 220-226

  Meyer, Markus R ^a   Wagmann, Lea ^a   Schneider Daum, Nicole ^b   Loretz, Brigitta ^b   De Souza Carvalho, Cristiane ^b   Lehr, Claus Michael ^b   Maurer, Hans H ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Drugs of abuse; Inhibitor; Novel psychoactive substances; p Glycoprotein; Substrate

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 3,4 METHYLENEDIOXY N BENZYLCATHINONE; ADENOSINE TRIPHOSPHATE; BENZEDRONE; DICLOFENSINE; GLAUCINE; JWH 200; MITRAGYNINE; MULTIDRUG RESISTANCE PROTEIN; PROPRANOLOL; PSYCHOTROPIC AGENT; UNCLASSIFIED DRUG; VERAPAMIL; NEUROLEPTIC AGENT; PROTEIN BINDING;

APPARENT PERMEABILITY; ARTICLE; CACO 2 CELL LINE; CONTROLLED ATMOSPHERE; CONTROLLED STUDY; DRUG TRANSPORT; ENZYME ACTIVITY; FOOD DRUG INTERACTION; HUMAN; HUMAN CELL; LUMINESCENCE; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL; PROTEIN INTERACTION; SUBSTRATE CONCENTRATION; SURFACE AREA; TRANSCYTOSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATE; ANTIPSYCHOTIC AGENTS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; P-GLYCOPROTEIN; PROTEIN BINDING;

EID: 84925491436     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.01.008     Document Type: Article

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