Verapamil quantification in human plasma by liquid chromatography coupled to tandem mass spectrometry: An application for bioequivalence study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 827, Issue 2, 2005, Pages 165-172

  Borges, Ney Carter Do C ^a   Mendes, Gustavo D ^a,b   Barrientos Astigarraga, Rafael E ^b   Galvinas, Paulo ^b   Oliveira, Celso H ^b   De Nucci, Gilberto ^a,b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b Cartesius Development of Clinical Research   (Brazil)

Author keywords

Bioequivalence; LC MS MS; Metoprolol; Verapamil

Indexed keywords

BIOLOGICAL MEMBRANES; IONIZATION; LIQUID CHROMATOGRAPHY; METHANOL; POSITIVE IONS; REACTION KINETICS;

BIOEQUIVALENCE; HUMAN PLASMA; LC-MS/MS; METOPROLOL; VERAPAMIL;

BODY FLUIDS;

FORMIC ACID; METHANOL; METOPROLOL; VERAPAMIL; WATER;

AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG FORMULATION; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MATHEMATICAL COMPUTING; NORMAL HUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THERAPEUTIC EQUIVALENCY; VERAPAMIL;

EID: 27644575940     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.07.012     Document Type: Article

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