Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells

Phytomedicine

Volumn 21, Issue 1, 2013, Pages 47-61

  Eid, Safaa Yehia ^a   El Readi, Mahmoud Zaki ^a,b   Eldin, Essam Eldin Mohamed Nour ^c   Fatani, Sameer Hassan ^c   Wink, Michael ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Al Azhar University   (Egypt)

^c UMM AL QURA UNIVERSITY   (Saudi Arabia)

Author keywords

Carotene; Colon cells; Digitonin; Leukaemia; Multidrug resistance; Sanguinarine

Indexed keywords

ALKALOID; AROMADENDRENE; BETA CAROTENE; CALCEIN; DIGITONIN; GLAUCINE; GLUCOSIDE; HARMINE; MENTHOL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PHENOL DERIVATIVE; POLYPHENOL DERIVATIVE; RHODAMINE 123; SANGUINARINE; SAPONIN; SITOSTEROL; TERPENOID; THYMOL; VERAPAMIL;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL STRAIN CACO 2; COLON CANCER; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOWN REGULATION; EFFUSION; GENE; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

COLON CELLS; DIGITONIN; LEUKAEMIA; MULTIDRUG RESISTANCE; SANGUINARINE; Β-CAROTENE;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BENZOPHENANTHRIDINES; BETA CAROTENE; CACO-2 CELLS; COLONIC NEOPLASMS; DIGITONIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; FLUORESCEINS; HUMANS; ISOQUINOLINES; LEUKEMIA; P-GLYCOPROTEIN; PHENOLS; PHYTOCHEMICALS; PHYTOTHERAPY; PLANT EXTRACTS; RHODAMINE 123; RNA, MESSENGER; TERPENES;

EID: 84888874157     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.07.019     Document Type: Article

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