Studies on the metabolism of mitragynine, the main alkaloid of the herbal drug Kratom, in rat and human urine using liquid chromatography-linear ion trapmass spectrometry

Journal of Mass Spectrometry

Volumn 44, Issue 8, 2009, Pages 1249-1261

  Philipp, Anika A ^a   Wissenbach, Dirk K ^a   Zoerntlein, Siegfried W ^b   Klein, Oliver N ^b   Kanogsunthornrat, Jidapha ^c   Maurer, Hans H ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c MINISTRY OF PUBLIC HEALTH   (Thailand)

Author keywords

Human; Kratom; LC MS; Metabolism; Mitragynine; Rat; Urine

Indexed keywords

HUMAN; KRATOM; LC-MS; MITRAGYNINE; URINE;

ALDEHYDES; BIOCHEMISTRY; BIOMOLECULES; BODY FLUIDS; CARBOXYLIC ACIDS; CHROMATOGRAPHIC ANALYSIS; EXTRACTION; LIQUIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES; ORGANIC ACIDS;

LIQUID CHROMATOGRAPHY;

ALCOHOL; ALDEHYDE; CARBOXYLIC ACID DERIVATIVE; ESTER; GLUCURONIDE; HERBACEOUS AGENT; METHYL ESTER; MITRAGYNINE; SULFATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONJUGATION; DEMETHYLATION; DRUG METABOLISM; DRUG STRUCTURE; HUMAN; HYDROLYSIS; ION TRAP MASS SPECTROMETRY; KRATOM; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY LINEAR ION TRAP MASS SPECTROMETRY; MALE; MASS SPECTROMETRY; MEDICINAL PLANT; METABOLITE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; REDUCTION; SOLID PHASE EXTRACTION; URINE;

ANALYTIC SAMPLE PREPARATION METHODS; ANIMALS; ARYLSULFATASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDASE; HUMANS; MALE; METABOLIC DETOXICATION, PHASE I; METABOLIC DETOXICATION, PHASE II; METABOLIC NETWORKS AND PATHWAYS; MITRAGYNA; MOLECULAR STRUCTURE; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; SECOLOGANIN TRYPTAMINE ALKALOIDS; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY;

MITRAGYNA SPECIOSA; RATTUS;

EID: 70349158718     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1607     Document Type: Article

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