Effects of intestinal ischemia/reperfusion on P-glycoprotein mediated biliary and renal excretion of rhodamine123 in rat

Drug Metabolism and Pharmacokinetics

Volumn 24, Issue 5, 2009, Pages 428-437

  Tomita, Mikio ^a   Kishimoto, Hisanao ^a   Takizawa, Yusuke ^a   Masahiro, Hayashi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Inducible niztric oxide synthesis (iNOS); Intestinal ischemia reperfusion; Kidney; Liver; P glycoprotein mediated transport

Indexed keywords

CIMETIDINE; CYCLOSPORIN A; GLYCOPROTEIN P; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; RHODAMINE 123; TETRYLAMMONIUM; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE FLOW; BILIARY EXCRETION; CONTROLLED STUDY; DRUG EXCRETION; FLOW RATE; GENE EXPRESSION; IN VIVO STUDY; INTESTINE ISCHEMIA; LIPID PEROXIDATION; MALE; MODEL; NONHUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; URINARY EXCRETION; WESTERN BLOTTING; WISTAR RAT;

EID: 71449106595     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.24.428     Document Type: Article

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