-
1
-
-
84877710696
-
Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of Marchigian Sardinian alcohol-preferring rats
-
1:CAS:528:DC%2BC3sXht1Sgs7%2FL 23630503
-
Ayanwuyi LO, Carvajal F, Lerma-Cabrera JM, Domi E, Bjork K, Ubaldi M, Heilig M, Roberto M, Ciccocioppo R, Cippitelli A (2013) Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of Marchigian Sardinian alcohol-preferring rats. Front Psychiatry 4:23
-
(2013)
Front Psychiatry
, vol.4
, pp. 23
-
-
Ayanwuyi, L.O.1
Carvajal, F.2
Lerma-Cabrera, J.M.3
Domi, E.4
Bjork, K.5
Ubaldi, M.6
Heilig, M.7
Roberto, M.8
Ciccocioppo, R.9
Cippitelli, A.10
-
2
-
-
84878613499
-
The NK1 receptor antagonist l822429 reduces heroin reinforcement
-
1:CAS:528:DC%2BC3sXmt1Shu7w%3D
-
Barbier E, Vendruscolo LF, Schlosburg JE, Edwards S, Juergens N, Park PE, Misra KK, Cheng K, Rice KC, Schank J, Schulteis G, Koob GF, Heilig M (2013) The NK1 receptor antagonist l822429 reduces heroin reinforcement. Neuropsychopharmaco Off Publ Am Coll Neuropsychopharmacol 38:976-984
-
(2013)
Neuropsychopharmaco off Publ Am Coll Neuropsychopharmacol
, vol.38
, pp. 976-984
-
-
Barbier, E.1
Vendruscolo, L.F.2
Schlosburg, J.E.3
Edwards, S.4
Juergens, N.5
Park, P.E.6
Misra, K.K.7
Cheng, K.8
Rice, K.C.9
Schank, J.10
Schulteis, G.11
Koob, G.F.12
Heilig, M.13
-
3
-
-
0032801869
-
Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like" effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats
-
1:CAS:528:DC%2BD3cXivFSgtLc%3D 10445369
-
Basso AM, Spina M, Rivier J, Vale W, Koob GF (1999) Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like" effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats. Psychopharmacology 145:21-30
-
(1999)
Psychopharmacology
, vol.145
, pp. 21-30
-
-
Basso, A.M.1
Spina, M.2
Rivier, J.3
Vale, W.4
Koob, G.F.5
-
4
-
-
0034945581
-
The ventral hippocampus and fear conditioning in rats. Different anterograde amnesias of fear after tetrodotoxin inactivation and infusion of the GABA(A) agonist muscimol
-
1:CAS:528:DC%2BD3MXktFCntb4%3D
-
Bast T, Zhang WN, Feldon J (2001) The ventral hippocampus and fear conditioning in rats. Different anterograde amnesias of fear after tetrodotoxin inactivation and infusion of the GABA(A) agonist muscimol. Exp Brain Res Experimentelle Hirnforschung Experimentation cerebrale 139:39-52
-
(2001)
Exp Brain Res Experimentelle Hirnforschung Experimentation Cerebrale
, vol.139
, pp. 39-52
-
-
Bast, T.1
Zhang, W.N.2
Feldon, J.3
-
5
-
-
78650679210
-
Local repeated corticotropin-releasing factor infusion exacerbates anxiety- and fear-related behavior: Differential involvement of the basolateral amygdala and medial prefrontal cortex
-
1:CAS:528:DC%2BC3MXhs1KltQ%3D%3D 21093544
-
Bijlsma EY, van Leeuwen ML, Westphal KG, Olivier B, Groenink L (2011) Local repeated corticotropin-releasing factor infusion exacerbates anxiety- and fear-related behavior: differential involvement of the basolateral amygdala and medial prefrontal cortex. Neuroscience 173:82-92
-
(2011)
Neuroscience
, vol.173
, pp. 82-92
-
-
Bijlsma, E.Y.1
Van Leeuwen, M.L.2
Westphal, K.G.3
Olivier, B.4
Groenink, L.5
-
6
-
-
79151484610
-
Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse
-
1:CAS:528:DC%2BC3MXpvVanug%3D%3D 20951730
-
Breese GR, Sinha R, Heilig M (2011) Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacol Ther 129:149-171
-
(2011)
Pharmacol Ther
, vol.129
, pp. 149-171
-
-
Breese, G.R.1
Sinha, R.2
Heilig, M.3
-
7
-
-
84868632808
-
Genetically selected alcohol preferring rats to model human alcoholism
-
Ciccocioppo R (2013) Genetically selected alcohol preferring rats to model human alcoholism. Curr Top Behav Neurosci 13:251-269
-
(2013)
Curr Top Behav Neurosci
, vol.13
, pp. 251-269
-
-
Ciccocioppo, R.1
-
8
-
-
0033051003
-
Antidepressant-like effect of ethanol revealed in the forced swimming test in Sardinian alcohol-preferring rats
-
1:CAS:528:DyaK1MXjvValu74%3D 10394996
-
Ciccocioppo R, Panocka I, Froldi R, Colombo G, Gessa GL, Massi M (1999) Antidepressant-like effect of ethanol revealed in the forced swimming test in Sardinian alcohol-preferring rats. Psychopharmacology 144:151-157
-
(1999)
Psychopharmacology
, vol.144
, pp. 151-157
-
-
Ciccocioppo, R.1
Panocka, I.2
Froldi, R.3
Colombo, G.4
Gessa, G.L.5
Massi, M.6
-
9
-
-
33750055822
-
Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: An animal model to study the neurobiology of alcoholism
-
Ciccocioppo R, Economidou D, Cippitelli A, Cucculelli M, Ubaldi M, Soverchia L, Lourdusamy A, Massi M (2006) Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism. Addict Biol 11:339-355
-
(2006)
Addict Biol
, vol.11
, pp. 339-355
-
-
Ciccocioppo, R.1
Economidou, D.2
Cippitelli, A.3
Cucculelli, M.4
Ubaldi, M.5
Soverchia, L.6
Lourdusamy, A.7
Massi, M.8
-
10
-
-
70350786679
-
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond
-
1:CAS:528:DC%2BD1MXhsVaisrrO 19913192
-
Ciccocioppo R, Gehlert DR, Ryabinin A, Kaur S, Cippitelli A, Thorsell A, Le AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, Economidou D, Stopponi S, Cannella N, Braconi S, Kallupi M, de Guglielmo G, Massi M, George DT, Gilman J, Hersh J, Tauscher JT, Hunt SP, Hommer D, Heilig M (2009) Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. Alcohol 43:491-498
-
(2009)
Alcohol
, vol.43
, pp. 491-498
-
-
Ciccocioppo, R.1
Gehlert, D.R.2
Ryabinin, A.3
Kaur, S.4
Cippitelli, A.5
Thorsell, A.6
Le, A.D.7
Hipskind, P.A.8
Hamdouchi, C.9
Lu, J.10
Hembre, E.J.11
Cramer, J.12
Song, M.13
McKinzie, D.14
Morin, M.15
Economidou, D.16
Stopponi, S.17
Cannella, N.18
Braconi, S.19
Kallupi, M.20
De Guglielmo, G.21
Massi, M.22
George, D.T.23
Gilman, J.24
Hersh, J.25
Tauscher, J.T.26
Hunt, S.P.27
Hommer, D.28
Heilig, M.29
more..
-
11
-
-
84891774134
-
Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: Significance for anxiety-like behaviors
-
1:CAS:528:DC%2BC2cXns1Wqsg%3D%3D
-
Ciccocioppo R, de Guglielmo G, Hansson AC, Ubaldi M, Kallupi M, Cruz MT, Oleata CS, Heilig M, Roberto M (2014) Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: significance for anxiety-like behaviors. J Neurosci Off J Soc Neurosci 34:363-372
-
(2014)
J Neurosci off J Soc Neurosci
, vol.34
, pp. 363-372
-
-
Ciccocioppo, R.1
De Guglielmo, G.2
Hansson, A.C.3
Ubaldi, M.4
Kallupi, M.5
Cruz, M.T.6
Oleata, C.S.7
Heilig, M.8
Roberto, M.9
-
12
-
-
82355193789
-
Endocannabinoid regulation of acute and protracted nicotine withdrawal: Effect of FAAH inhibition
-
1:CAS:528:DC%2BC3MXhs1GgtbzK 22140525
-
Cippitelli A, Astarita G, Duranti A, Caprioli G, Ubaldi M, Stopponi S, Kallupi M, Sagratini G, Rodriguez de Fonseca F, Piomelli D, Ciccocioppo R (2011a) Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. PLoS One 6:e28142
-
(2011)
PLoS One
, vol.6
, pp. 28142
-
-
Cippitelli, A.1
Astarita, G.2
Duranti, A.3
Caprioli, G.4
Ubaldi, M.5
Stopponi, S.6
Kallupi, M.7
Sagratini, G.8
Rodriguez De Fonseca, F.9
Piomelli, D.10
Ciccocioppo, R.11
-
13
-
-
79961208929
-
The novel, selective, brain-penetrant neuropeptide y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety
-
1:CAS:528:DC%2BC3MXhtValurrJ 21145691
-
Cippitelli A, Rezvani AH, Robinson JE, Eisenberg L, Levin ED, Bonaventure P, Motley ST, Lovenberg TW, Heilig M, Thorsell A (2011b) The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety. Alcohol 45:567-576
-
(2011)
Alcohol
, vol.45
, pp. 567-576
-
-
Cippitelli, A.1
Rezvani, A.H.2
Robinson, J.E.3
Eisenberg, L.4
Levin, E.D.5
Bonaventure, P.6
Motley, S.T.7
Lovenberg, T.W.8
Heilig, M.9
Thorsell, A.10
-
14
-
-
81255164797
-
Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats
-
1:CAS:528:DC%2BC3MXhs1GjsrrF 22036774
-
Cippitelli A, Damadzic R, Singley E, Thorsell A, Ciccocioppo R, Eskay RL, Heilig M (2012) Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats. Pharmacol Biochem Behav 100:522-529
-
(2012)
Pharmacol Biochem Behav
, vol.100
, pp. 522-529
-
-
Cippitelli, A.1
Damadzic, R.2
Singley, E.3
Thorsell, A.4
Ciccocioppo, R.5
Eskay, R.L.6
Heilig, M.7
-
15
-
-
79958786543
-
Stress-induced alterations in anxiety-like behavior and adaptations in plasticity in the bed nucleus of the stria terminalis
-
1:CAS:528:DC%2BC3MXnslKrtb0%3D 21396387
-
Conrad KL, Louderback KM, Gessner CP, Winder DG (2011) Stress-induced alterations in anxiety-like behavior and adaptations in plasticity in the bed nucleus of the stria terminalis. Physiol Behav 104:248-256
-
(2011)
Physiol Behav
, vol.104
, pp. 248-256
-
-
Conrad, K.L.1
Louderback, K.M.2
Gessner, C.P.3
Winder, D.G.4
-
16
-
-
0036551759
-
Targeted mutations of the corticotropin-releasing factor system: Effects on physiology and behavior
-
1:CAS:528:DC%2BD38XnsFGktb4%3D 12359502
-
Contarino A, Gold LH (2002) Targeted mutations of the corticotropin-releasing factor system: effects on physiology and behavior. Neuropeptides 36:103-116
-
(2002)
Neuropeptides
, vol.36
, pp. 103-116
-
-
Contarino, A.1
Gold, L.H.2
-
18
-
-
0037470233
-
Defensive burying in rodents: Ethology, neurobiology and psychopharmacology
-
De Boer SF, Koolhaas JM (2003) Defensive burying in rodents: ethology, neurobiology and psychopharmacology. Eur J Pharmacol 463:145-161
-
(2003)
Eur J Pharmacol
, vol.463
, pp. 145-161
-
-
De Boer, S.F.1
Koolhaas, J.M.2
-
19
-
-
0027080480
-
The effect of corticotropin-releasing factor (CRF) on autonomic and behavioral responses during shock-prod burying test in rats
-
1:CAS:528:DyaK3sXpsVKqug%3D%3D 1494497
-
Diamant M, Croiset G, de Wied D (1992) The effect of corticotropin-releasing factor (CRF) on autonomic and behavioral responses during shock-prod burying test in rats. Peptides 13:1149-1158
-
(1992)
Peptides
, vol.13
, pp. 1149-1158
-
-
Diamant, M.1
Croiset, G.2
De Wied, D.3
-
20
-
-
0033568969
-
A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seeking
-
1:STN:280:DC%2BD3c3ns1emsQ%3D%3D
-
Erb S, Stewart J (1999) A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seeking. J Neurosci Off J Soc Neurosci 19:RC35
-
(1999)
J Neurosci off J Soc Neurosci
, vol.19
, pp. 35
-
-
Erb, S.1
Stewart, J.2
-
21
-
-
33750931628
-
Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats
-
1:CAS:528:DC%2BD28Xht1aksbvN
-
Funk CK, O'Dell LE, Crawford EF, Koob GF (2006) Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats. J Neurosci Off J Soc Neurosci 26:11324-11332
-
(2006)
J Neurosci off J Soc Neurosci
, vol.26
, pp. 11324-11332
-
-
Funk, C.K.1
O'Dell, L.E.2
Crawford, E.F.3
Koob, G.F.4
-
22
-
-
33847772007
-
3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo [1,2-b]pyridazine: A novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism
-
1:CAS:528:DC%2BD2sXjsVCrur8%3D
-
Gehlert DR, Cippitelli A, Thorsell A, Le AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, Ciccocioppo R, Heilig M (2007) 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo [1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism. J Neurosci Off J Soc Neurosci 27:2718-2726
-
(2007)
J Neurosci off J Soc Neurosci
, vol.27
, pp. 2718-2726
-
-
Gehlert, D.R.1
Cippitelli, A.2
Thorsell, A.3
Le, A.D.4
Hipskind, P.A.5
Hamdouchi, C.6
Lu, J.7
Hembre, E.J.8
Cramer, J.9
Song, M.10
McKinzie, D.11
Morin, M.12
Ciccocioppo, R.13
Heilig, M.14
-
23
-
-
0034973386
-
Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in rats
-
1:STN:280:DC%2BD3MzitVensQ%3D%3D 11390634
-
Goosens KA, Maren S (2001) Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in rats. Learn Mem 8:148-155
-
(2001)
Learn Mem
, vol.8
, pp. 148-155
-
-
Goosens, K.A.1
Maren, S.2
-
24
-
-
1842531466
-
Chemical lesion of the bed nucleus of the stria terminalis blocks the behavioral consequences of uncontrollable stress
-
Hammack SE, Richey KJ, Watkins LR, Maier SF (2004) Chemical lesion of the bed nucleus of the stria terminalis blocks the behavioral consequences of uncontrollable stress. Behav Neurosci 118:443-448
-
(2004)
Behav Neurosci
, vol.118
, pp. 443-448
-
-
Hammack, S.E.1
Richey, K.J.2
Watkins, L.R.3
Maier, S.F.4
-
25
-
-
33750056368
-
Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress
-
1:CAS:528:DC%2BD28XhtFais7fK 17015825
-
Hansson AC, Cippitelli A, Sommer WH, Fedeli A, Bjork K, Soverchia L, Terasmaa A, Massi M, Heilig M, Ciccocioppo R (2006) Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress. Proc Natl Acad Sci U S A 103:15236-15241
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15236-15241
-
-
Hansson, A.C.1
Cippitelli, A.2
Sommer, W.H.3
Fedeli, A.4
Bjork, K.5
Soverchia, L.6
Terasmaa, A.7
Massi, M.8
Heilig, M.9
Ciccocioppo, R.10
-
26
-
-
33947133287
-
Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol
-
1:CAS:528:DC%2BD2sXhtVOqurrP 17407495
-
Hansson AC, Cippitelli A, Sommer WH, Ciccocioppo R, Heilig M (2007) Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol. Addict Biol 12:30-34
-
(2007)
Addict Biol
, vol.12
, pp. 30-34
-
-
Hansson, A.C.1
Cippitelli, A.2
Sommer, W.H.3
Ciccocioppo, R.4
Heilig, M.5
-
27
-
-
34447644753
-
A key role for corticotropin-releasing factor in alcohol dependence
-
1:CAS:528:DC%2BD2sXotlaju74%3D 17629579
-
Heilig M, Koob GF (2007) A key role for corticotropin-releasing factor in alcohol dependence. Trends Neurosci 30:399-406
-
(2007)
Trends Neurosci
, vol.30
, pp. 399-406
-
-
Heilig, M.1
Koob, G.F.2
-
28
-
-
0030870660
-
Corticotropin-releasing factor CRF1, but not CRF2, receptors mediate anxiogenic-like behavior
-
1:CAS:528:DyaK2sXltl2kt7w%3D 9299637
-
Heinrichs SC, Lapsansky J, Lovenberg TW, De Souza EB, Chalmers DT (1997) Corticotropin-releasing factor CRF1, but not CRF2, receptors mediate anxiogenic-like behavior. Regul Pept 71:15-21
-
(1997)
Regul Pept
, vol.71
, pp. 15-21
-
-
Heinrichs, S.C.1
Lapsansky, J.2
Lovenberg, T.W.3
De Souza, E.B.4
Chalmers, D.T.5
-
29
-
-
0036289254
-
Brain penetrance, receptor occupancy and antistress in vivo efficacy of a small molecule corticotropin releasing factor type i receptor selective antagonist
-
1:CAS:528:DC%2BD38XkvFyqtrs%3D
-
Heinrichs SC, De Souza EB, Schulteis G, Lapsansky JL, Grigoriadis DE (2002) Brain penetrance, receptor occupancy and antistress in vivo efficacy of a small molecule corticotropin releasing factor type I receptor selective antagonist. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol 27:194-202
-
(2002)
Neuropsychopharmacol off Publ Am Coll Neuropsychopharmacol
, vol.27
, pp. 194-202
-
-
Heinrichs, S.C.1
De Souza, E.B.2
Schulteis, G.3
Lapsansky, J.L.4
Grigoriadis, D.E.5
-
30
-
-
84873369791
-
Enhanced GABAergic transmission in the central nucleus of the amygdala of genetically selected Marchigian Sardinian rats: Alcohol and CRF effects
-
1:CAS:528:DC%2BC3sXhs1ent7o%3D 23220399
-
Herman MA, Kallupi M, Luu G, Oleata CS, Heilig M, Koob GF, Ciccocioppo R, Roberto M (2013) Enhanced GABAergic transmission in the central nucleus of the amygdala of genetically selected Marchigian Sardinian rats: alcohol and CRF effects. Neuropharmacology 67:337-348
-
(2013)
Neuropharmacology
, vol.67
, pp. 337-348
-
-
Herman, M.A.1
Kallupi, M.2
Luu, G.3
Oleata, C.S.4
Heilig, M.5
Koob, G.F.6
Ciccocioppo, R.7
Roberto, M.8
-
31
-
-
0033808075
-
Suppression of conditioned fear by administration of CRF receptor antagonist CP-154,526
-
1:CAS:528:DC%2BD3cXnt1Ohu7s%3D 11071021
-
Hikichi T, Akiyoshi J, Yamamoto Y, Tsutsumi T, Isogawa K, Nagayama H (2000) Suppression of conditioned fear by administration of CRF receptor antagonist CP-154,526. Pharmacopsychiatry 33:189-193
-
(2000)
Pharmacopsychiatry
, vol.33
, pp. 189-193
-
-
Hikichi, T.1
Akiyoshi, J.2
Yamamoto, Y.3
Tsutsumi, T.4
Isogawa, K.5
Nagayama, H.6
-
32
-
-
5144232529
-
Involvement of central amygdalar and bed nucleus of the stria terminalis corticotropin-releasing factor in behavioral responses to social defeat
-
1:CAS:528:DC%2BD2cXptl2ktLc%3D 15506887
-
Jasnow AM, Davis M, Huhman KL (2004) Involvement of central amygdalar and bed nucleus of the stria terminalis corticotropin-releasing factor in behavioral responses to social defeat. Behav Neurosci 118:1052-1061
-
(2004)
Behav Neurosci
, vol.118
, pp. 1052-1061
-
-
Jasnow, A.M.1
Davis, M.2
Huhman, K.L.3
-
33
-
-
34250665463
-
Pain-related anxiety-like behavior requires CRF1 receptors in the amygdala
-
Ji G, Fu Y, Ruppert KA, Neugebauer V (2007) Pain-related anxiety-like behavior requires CRF1 receptors in the amygdala. Mol Pain 3:13
-
(2007)
Mol Pain
, vol.3
, pp. 13
-
-
Ji, G.1
Fu, Y.2
Ruppert, K.A.3
Neugebauer, V.4
-
34
-
-
75149143341
-
The role of CRF and CRF-related peptides in the dark side of addiction
-
1:CAS:528:DC%2BC3cXhtlels7c%3D 19912996
-
Koob GF (2010) The role of CRF and CRF-related peptides in the dark side of addiction. Brain Res 1314:3-14
-
(2010)
Brain Res
, vol.1314
, pp. 3-14
-
-
Koob, G.F.1
-
35
-
-
0028357440
-
Effect of corticotropin-releasing factor antagonist on behavioral and neuroendocrine responses during exposure to defensive burying paradigm in rats
-
1:CAS:528:DyaK2cXktVWntLg%3D 8084889
-
Korte SM, Korte-Bouws GA, Bohus B, Koob GF (1994) Effect of corticotropin-releasing factor antagonist on behavioral and neuroendocrine responses during exposure to defensive burying paradigm in rats. Physiol Behav 56:115-120
-
(1994)
Physiol Behav
, vol.56
, pp. 115-120
-
-
Korte, S.M.1
Korte-Bouws, G.A.2
Bohus, B.3
Koob, G.F.4
-
36
-
-
0034076609
-
Emotion circuits in the brain
-
1:CAS:528:DC%2BD3cXjs1Gmsr4%3D 10845062
-
LeDoux JE (2000) Emotion circuits in the brain. Annu Rev Neurosci 23:155-184
-
(2000)
Annu Rev Neurosci
, vol.23
, pp. 155-184
-
-
Ledoux, J.E.1
-
37
-
-
34548795901
-
Microinfusion of pituitary adenylate cyclase-activating polypeptide into the central nucleus of amygdala of the rat produces a shift from an active to passive mode of coping in the shock-probe fear/defensive burying test
-
1906870 17641738
-
Legradi G, Das M, Giunta B, Hirani K, Mitchell EA, Diamond DM (2007) Microinfusion of pituitary adenylate cyclase-activating polypeptide into the central nucleus of amygdala of the rat produces a shift from an active to passive mode of coping in the shock-probe fear/defensive burying test. Neural Plast 2007:79102
-
(2007)
Neural Plast
, vol.2007
, pp. 79102
-
-
Legradi, G.1
Das, M.2
Giunta, B.3
Hirani, K.4
Mitchell, E.A.5
Diamond, D.M.6
-
39
-
-
0029117641
-
Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis
-
1:STN:280:DyaK2MzntV2isQ%3D%3D
-
Merlo Pich E, Lorang M, Yeganeh M, Rodriguez de Fonseca F, Raber J, Koob GF, Weiss F (1995) Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis. J Neurosci Off J Soc Neurosci 15:5439-5447
-
(1995)
J Neurosci off J Soc Neurosci
, vol.15
, pp. 5439-5447
-
-
Merlo Pich, E.1
Lorang, M.2
Yeganeh, M.3
Rodriguez De Fonseca, F.4
Raber, J.5
Koob, G.F.6
Weiss, F.7
-
40
-
-
4043163435
-
Getting closer to affective disorders: The role of CRH receptor systems
-
Muller MB, Wurst W (2004) Getting closer to affective disorders: the role of CRH receptor systems. Trends Mol Med 10:409-415
-
(2004)
Trends Mol Med
, vol.10
, pp. 409-415
-
-
Muller, M.B.1
Wurst, W.2
-
41
-
-
0141542646
-
Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
-
Muller MB, Zimmermann S, Sillaber I, Hagemeyer TP, Deussing JM, Timpl P, Kormann MS, Droste SK, Kuhn R, Reul JM, Holsboer F, Wurst W (2003) Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress. Nat Neurosci 6:1100-1107
-
(2003)
Nat Neurosci
, vol.6
, pp. 1100-1107
-
-
Muller, M.B.1
Zimmermann, S.2
Sillaber, I.3
Hagemeyer, T.P.4
Deussing, J.M.5
Timpl, P.6
Kormann, M.S.7
Droste, S.K.8
Kuhn, R.9
Reul, J.M.10
Holsboer, F.11
Wurst, W.12
-
42
-
-
25144441630
-
The neurobiology of depression: Inroads to treatment and new drug discovery
-
1:CAS:528:DC%2BD2MXhtFSksbrK 16124836
-
Nemeroff CB, Vale WW (2005) The neurobiology of depression: inroads to treatment and new drug discovery. J Clin Psychiatry 66(Suppl 7):5-13
-
(2005)
J Clin Psychiatry
, vol.66
, pp. 5-13
-
-
Nemeroff, C.B.1
Vale, W.W.2
-
43
-
-
0036204717
-
Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake
-
1:CAS:528:DC%2BD38XitFWltb8%3D 11900791
-
Olive MF, Koenig HN, Nannini MA, Hodge CW (2002) Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake. Pharmacol Biochem Behav 72:213-220
-
(2002)
Pharmacol Biochem Behav
, vol.72
, pp. 213-220
-
-
Olive, M.F.1
Koenig, H.N.2
Nannini, M.A.3
Hodge, C.W.4
-
44
-
-
1642452720
-
Modulation of multiple ethanol withdrawal-induced anxiety-like behavior by CRF and CRF1 receptors
-
1:CAS:528:DC%2BD2cXnvVOhuw%3D%3D 14751471
-
Overstreet DH, Knapp DJ, Breese GR (2004) Modulation of multiple ethanol withdrawal-induced anxiety-like behavior by CRF and CRF1 receptors. Pharmacol Biochem Behav 77:405-413
-
(2004)
Pharmacol Biochem Behav
, vol.77
, pp. 405-413
-
-
Overstreet, D.H.1
Knapp, D.J.2
Breese, G.R.3
-
45
-
-
40949132595
-
Dissociation of the morphological correlates of stress-induced anxiety and fear
-
1:STN:280:DC%2BD1c3gsFCisw%3D%3D 18336570
-
Pego JM, Morgado P, Pinto LG, Cerqueira JJ, Almeida OF, Sousa N (2008) Dissociation of the morphological correlates of stress-induced anxiety and fear. Eur J Neurosci 27:1503-1516
-
(2008)
Eur J Neurosci
, vol.27
, pp. 1503-1516
-
-
Pego, J.M.1
Morgado, P.2
Pinto, L.G.3
Cerqueira, J.J.4
Almeida, O.F.5
Sousa, N.6
-
46
-
-
0022374863
-
Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
-
1:STN:280:DyaL28%2Fht12htw%3D%3D 2864480
-
Pellow S, Chopin P, File SE, Briley M (1985) Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 14:149-167
-
(1985)
J Neurosci Methods
, vol.14
, pp. 149-167
-
-
Pellow, S.1
Chopin, P.2
File, S.E.3
Briley, M.4
-
47
-
-
0018181582
-
Burying as a defensive response in rats
-
Pinel JPJ, Treit D (1978) Burying as a defensive response in rats. J Comp Physiol Psychol 92
-
(1978)
J Comp Physiol Psychol
, vol.92
-
-
Jpj, P.1
Treit, D.2
-
48
-
-
37249042346
-
MPZP: A novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist
-
1:CAS:528:DC%2BD2sXhsVOlsbbF 18031798
-
Richardson HN, Zhao Y, Fekete EM, Funk CK, Wirsching P, Janda KD, Zorrilla EP, Koob GF (2008) MPZP: a novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist. Pharmacol Biochem Behav 88:497-510
-
(2008)
Pharmacol Biochem Behav
, vol.88
, pp. 497-510
-
-
Richardson, H.N.1
Zhao, Y.2
Fekete, E.M.3
Funk, C.K.4
Wirsching, P.5
Janda, K.D.6
Zorrilla, E.P.7
Koob, G.F.8
-
49
-
-
77950369440
-
Corticotropin releasing factor-induced amygdala gamma-aminobutyric acid release plays a key role in alcohol dependence
-
1:CAS:528:DC%2BC3cXksFCks7s%3D 20060104
-
Roberto M, Cruz MT, Gilpin NW, Sabino V, Schweitzer P, Bajo M, Cottone P, Madamba SG, Stouffer DG, Zorrilla EP, Koob GF, Siggins GR, Parsons LH (2010) Corticotropin releasing factor-induced amygdala gamma-aminobutyric acid release plays a key role in alcohol dependence. Biol Psychiatry 67:831-839
-
(2010)
Biol Psychiatry
, vol.67
, pp. 831-839
-
-
Roberto, M.1
Cruz, M.T.2
Gilpin, N.W.3
Sabino, V.4
Schweitzer, P.5
Bajo, M.6
Cottone, P.7
Madamba, S.G.8
Stouffer, D.G.9
Zorrilla, E.P.10
Koob, G.F.11
Siggins, G.R.12
Parsons, L.H.13
-
50
-
-
0031303718
-
The role of the central amygdala in stress and adaption
-
1:STN:280:DyaK1c%2FmsFWhug%3D%3D 9401606
-
Roozendaal B, Koolhaas JM, Bohus B (1997) The role of the central amygdala in stress and adaption. Acta Physiol Scand Suppl 640:51-54
-
(1997)
Acta Physiol Scand Suppl
, vol.640
, pp. 51-54
-
-
Roozendaal, B.1
Koolhaas, J.M.2
Bohus, B.3
-
51
-
-
0035023610
-
The role of corticotropin-releasing factor in drug addiction
-
1:CAS:528:DC%2BD3MXkt1Gnurk%3D 11356984
-
Sarnyai Z, Shaham Y, Heinrichs SC (2001) The role of corticotropin-releasing factor in drug addiction. Pharmacol Rev 53:209-243
-
(2001)
Pharmacol Rev
, vol.53
, pp. 209-243
-
-
Sarnyai, Z.1
Shaham, Y.2
Heinrichs, S.C.3
-
52
-
-
77957110114
-
Interacting effects of CRHR1 gene and stressful life events on drinking initiation and progression among 19-year-olds
-
1:CAS:528:DC%2BC3cXotVWrt78%3D
-
Schmid B, Blomeyer D, Treutlein J, Zimmermann US, Buchmann AF, Schmidt MH, Esser G, Rietschel M, Banaschewski T, Schumann G, Laucht M (2010) Interacting effects of CRHR1 gene and stressful life events on drinking initiation and progression among 19-year-olds. Int J Neuropsychopharmacol Off Sci J Coll Internationale Neuropsychopharmacologicum 13:703-714
-
(2010)
Int J Neuropsychopharmacol off Sci J Coll Internationale Neuropsychopharmacologicum
, vol.13
, pp. 703-714
-
-
Schmid, B.1
Blomeyer, D.2
Treutlein, J.3
Zimmermann, U.S.4
Buchmann, A.F.5
Schmidt, M.H.6
Esser, G.7
Rietschel, M.8
Banaschewski, T.9
Schumann, G.10
Laucht, M.11
-
53
-
-
0013522651
-
CP-154,526: A potent and selective nonpeptide antagonist of corticotropin releasing factor receptors
-
1:CAS:528:DyaK28XlslGrs74%3D 8816826
-
Schulz DW, Mansbach RS, Sprouse J, Braselton JP, Collins J, Corman M, Dunaiskis A, Faraci S, Schmidt AW, Seeger T, Seymour P, Tingley FD 3rd, Winston EN, Chen YL, Heym J (1996) CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors. Proc Natl Acad Sci U S A 93:10477-10482
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10477-10482
-
-
Schulz, D.W.1
Mansbach, R.S.2
Sprouse, J.3
Braselton, J.P.4
Collins, J.5
Corman, M.6
Dunaiskis, A.7
Faraci, S.8
Schmidt, A.W.9
Seeger, T.10
Seymour, P.11
Tingley, F.D.12
Winston, E.N.13
Chen, Y.L.14
Heym, J.15
-
54
-
-
84889870165
-
Emerging role for corticotropin releasing factor signaling in the bed nucleus of the stria terminalis at the intersection of stress and reward
-
Silberman Y, Winder DG (2013) Emerging role for corticotropin releasing factor signaling in the bed nucleus of the stria terminalis at the intersection of stress and reward. Front Psychiatry 4:42
-
(2013)
Front Psychiatry
, vol.4
, pp. 42
-
-
Silberman, Y.1
Winder, D.G.2
-
55
-
-
0031925646
-
Corticotropin-releasing hormone receptor (type I) antisense targeting reduces anxiety
-
1:CAS:528:DyaK1cXjt1Gmsrc%3D 9639273
-
Skutella T, Probst JC, Renner U, Holsboer F, Behl C (1998) Corticotropin-releasing hormone receptor (type I) antisense targeting reduces anxiety. Neuroscience 85:795-805
-
(1998)
Neuroscience
, vol.85
, pp. 795-805
-
-
Skutella, T.1
Probst, J.C.2
Renner, U.3
Holsboer, F.4
Behl, C.5
-
56
-
-
0032104267
-
Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development
-
1:CAS:528:DyaK1cXktFOlurg%3D 9655498
-
Smith GW, Aubry JM, Dellu F, Contarino A, Bilezikjian LM, Gold LH, Chen R, Marchuk Y, Hauser C, Bentley CA, Sawchenko PE, Koob GF, Vale W, Lee KF (1998) Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron 20:1093-1102
-
(1998)
Neuron
, vol.20
, pp. 1093-1102
-
-
Smith, G.W.1
Aubry, J.M.2
Dellu, F.3
Contarino, A.4
Bilezikjian, L.M.5
Gold, L.H.6
Chen, R.7
Marchuk, Y.8
Hauser, C.9
Bentley, C.A.10
Sawchenko, P.E.11
Koob, G.F.12
Vale, W.13
Lee, K.F.14
-
57
-
-
37349041024
-
Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence
-
Sommer WH, Rimondini R, Hansson AC, Hipskind PA, Gehlert DR, Barr CS, Heilig MA (2008) Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence. Biol Psychiatry 63:139-145
-
(2008)
Biol Psychiatry
, vol.63
, pp. 139-145
-
-
Sommer, W.H.1
Rimondini, R.2
Hansson, A.C.3
Hipskind, P.A.4
Gehlert, D.R.5
Barr, C.S.6
Heilig, M.A.7
-
58
-
-
84884981910
-
Optogenetic strategies to investigate neural circuitry engaged by stress
-
Sparta DR, Jennings JH, Ung RL, Stuber GD (2013) Optogenetic strategies to investigate neural circuitry engaged by stress. Behav Brain Res 255:19-25
-
(2013)
Behav Brain Res
, vol.255
, pp. 19-25
-
-
Sparta, D.R.1
Jennings, J.H.2
Ung, R.L.3
Stuber, G.D.4
-
59
-
-
17344362093
-
Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1
-
1:CAS:528:DyaK1cXls1Crtb8%3D 9620773
-
Timpl P, Spanagel R, Sillaber I, Kresse A, Reul JM, Stalla GK, Blanquet V, Steckler T, Holsboer F, Wurst W (1998) Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Nat Genet 19:162-166
-
(1998)
Nat Genet
, vol.19
, pp. 162-166
-
-
Timpl, P.1
Spanagel, R.2
Sillaber, I.3
Kresse, A.4
Reul, J.M.5
Stalla, G.K.6
Blanquet, V.7
Steckler, T.8
Holsboer, F.9
Wurst, W.10
-
60
-
-
77953025533
-
Activation of central CRF receptor 1 by cortagine results in enhanced passive coping with a naturalistic threat in mice
-
1:CAS:528:DC%2BC3cXmtlymsLs%3D 20036073
-
Tovote P, Farrokhi CB, Gonzales RM, Schnitzbauer U, Blanchard DC, Blanchard RJ, Spiess J (2010) Activation of central CRF receptor 1 by cortagine results in enhanced passive coping with a naturalistic threat in mice. Psychoneuroendocrinology 35:887-895
-
(2010)
Psychoneuroendocrinology
, vol.35
, pp. 887-895
-
-
Tovote, P.1
Farrokhi, C.B.2
Gonzales, R.M.3
Schnitzbauer, U.4
Blanchard, D.C.5
Blanchard, R.J.6
Spiess, J.7
-
61
-
-
33745712822
-
Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples
-
1:CAS:528:DC%2BD28XkvVyrtLY%3D 16550213
-
Treutlein J, Kissling C, Frank J, Wiemann S, Dong L, Depner M, Saam C, Lascorz J, Soyka M, Preuss UW, Rujescu D, Skowronek MH, Rietschel M, Spanagel R, Heinz A, Laucht M, Mann K, Schumann G (2006) Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. Mol Psychiatry 11:594-602
-
(2006)
Mol Psychiatry
, vol.11
, pp. 594-602
-
-
Treutlein, J.1
Kissling, C.2
Frank, J.3
Wiemann, S.4
Dong, L.5
Depner, M.6
Saam, C.7
Lascorz, J.8
Soyka, M.9
Preuss, U.W.10
Rujescu, D.11
Skowronek, M.H.12
Rietschel, M.13
Spanagel, R.14
Heinz, A.15
Laucht, M.16
Mann, K.17
Schumann, G.18
-
62
-
-
0019782980
-
Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin
-
1:CAS:528:DyaL3MXlvF2htbc%3D 6267699
-
Vale W, Spiess J, Rivier C, Rivier J (1981) Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science 213:1394-1397
-
(1981)
Science
, vol.213
, pp. 1394-1397
-
-
Vale, W.1
Spiess, J.2
Rivier, C.3
Rivier, J.4
-
63
-
-
84869884316
-
Stress shifts the response of the bed nucleus of the stria terminalis to an anxiogenic mode
-
Ventura-Silva AP, Pego JM, Sousa JC, Marques AR, Rodrigues AJ, Marques F, Cerqueira JJ, Almeida OF, Sousa N (2012) Stress shifts the response of the bed nucleus of the stria terminalis to an anxiogenic mode. Eur J Neurosci 36:3396-3406
-
(2012)
Eur J Neurosci
, vol.36
, pp. 3396-3406
-
-
Ventura-Silva, A.P.1
Pego, J.M.2
Sousa, J.C.3
Marques, A.R.4
Rodrigues, A.J.5
Marques, F.6
Cerqueira, J.J.7
Almeida, O.F.8
Sousa, N.9
-
64
-
-
0030445812
-
In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: Suppression of pituitary ACTH release and peripheral inflammation
-
1:CAS:528:DyaK28Xnt1Kju7c%3D 8940412
-
Webster EL, Lewis DB, Torpy DJ, Zachman EK, Rice KC, Chrousos GP (1996) In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation. Endocrinology 137:5747-5750
-
(1996)
Endocrinology
, vol.137
, pp. 5747-5750
-
-
Webster, E.L.1
Lewis, D.B.2
Torpy, D.J.3
Zachman, E.K.4
Rice, K.C.5
Chrousos, G.P.6
-
65
-
-
36348935684
-
Subtype-selective corticotropin-releasing factor receptor agonists exert contrasting, but not opposite, effects on anxiety-related behavior in rats
-
1:CAS:528:DC%2BD2sXhsVSgsLjO 17855476
-
Zhao Y, Valdez GR, Fekete EM, Rivier JE, Vale WW, Rice KC, Weiss F, Zorrilla EP (2007) Subtype-selective corticotropin-releasing factor receptor agonists exert contrasting, but not opposite, effects on anxiety-related behavior in rats. J Pharmacol Exp Ther 323:846-854
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 846-854
-
-
Zhao, Y.1
Valdez, G.R.2
Fekete, E.M.3
Rivier, J.E.4
Vale, W.W.5
Rice, K.C.6
Weiss, F.7
Zorrilla, E.P.8
-
66
-
-
3543078103
-
The therapeutic potential of CRF1 antagonists for anxiety
-
1:CAS:528:DC%2BD2cXltVOgu78%3D 15212620
-
Zorrilla EP, Koob GF (2004) The therapeutic potential of CRF1 antagonists for anxiety. Expert Opin Investig Drugs 13:799-828
-
(2004)
Expert Opin Investig Drugs
, vol.13
, pp. 799-828
-
-
Zorrilla, E.P.1
Koob, G.F.2
-
67
-
-
0035207886
-
Changes in levels of regional CRF-like-immunoreactivity and plasma corticosterone during protracted drug withdrawal in dependent rats
-
1:CAS:528:DC%2BD38XnsVKqtw%3D%3D 11797058
-
Zorrilla EP, Valdez GR, Weiss F (2001) Changes in levels of regional CRF-like-immunoreactivity and plasma corticosterone during protracted drug withdrawal in dependent rats. Psychopharmacology 158:374-381
-
(2001)
Psychopharmacology
, vol.158
, pp. 374-381
-
-
Zorrilla, E.P.1
Valdez, G.R.2
Weiss, F.3
|