메뉴 건너뛰기




Volumn 30, Issue 8, 2007, Pages 399-406

A key role for corticotropin-releasing factor in alcohol dependence

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; NALTREXONE; OPIATE ANTAGONIST;

EID: 34447644753     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tins.2007.06.006     Document Type: Review
Times cited : (412)

References (71)
  • 1
    • 0037010474 scopus 로고    scopus 로고
    • Selected major risk factors and global and regional burden of disease
    • Ezzati M., et al. Selected major risk factors and global and regional burden of disease. Lancet 360 (2002) 1347-1360
    • (2002) Lancet , vol.360 , pp. 1347-1360
    • Ezzati, M.1
  • 2
    • 21344469970 scopus 로고    scopus 로고
    • The genetics of addictions: uncovering the genes
    • Goldman D., et al. The genetics of addictions: uncovering the genes. Nat. Rev. Genet. 6 (2005) 521-532
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 521-532
    • Goldman, D.1
  • 3
    • 27644524900 scopus 로고    scopus 로고
    • Neurobiology of addiction: treatment and public policy ramifications
    • Dackis C., and O'Brien C.P. Neurobiology of addiction: treatment and public policy ramifications. Nat. Neurosci. 8 (2005) 1431-1436
    • (2005) Nat. Neurosci. , vol.8 , pp. 1431-1436
    • Dackis, C.1    O'Brien, C.P.2
  • 4
    • 76549251315 scopus 로고
    • A study in alcoholism; clinical, social-psychiatric and genetic investigations
    • Åmark C. A study in alcoholism; clinical, social-psychiatric and genetic investigations. Acta Psychiatr. Neurol. Scand. 70 Supplementum (1951) 1-283
    • (1951) Acta Psychiatr. Neurol. Scand. , vol.70 , Issue.Supplementum , pp. 1-283
    • Åmark, C.1
  • 5
    • 14844325257 scopus 로고    scopus 로고
    • Continuity of binge and harmful drinking from late adolescence to early adulthood
    • McCarty C.A., et al. Continuity of binge and harmful drinking from late adolescence to early adulthood. Pediatrics 114 (2004) 714-719
    • (2004) Pediatrics , vol.114 , pp. 714-719
    • McCarty, C.A.1
  • 6
    • 4143069059 scopus 로고    scopus 로고
    • Another look at heavy episodic drinking and alcohol use disorders among college and noncollege youth
    • Dawson D.A., et al. Another look at heavy episodic drinking and alcohol use disorders among college and noncollege youth. J. Stud. Alcohol 65 (2004) 477-488
    • (2004) J. Stud. Alcohol , vol.65 , pp. 477-488
    • Dawson, D.A.1
  • 7
    • 0037278737 scopus 로고    scopus 로고
    • Reward craving and withdrawal relief craving: assessment of different motivational pathways to alcohol intake
    • Heinz A., et al. Reward craving and withdrawal relief craving: assessment of different motivational pathways to alcohol intake. Alcohol Alcohol. 38 (2003) 35-39
    • (2003) Alcohol Alcohol. , vol.38 , pp. 35-39
    • Heinz, A.1
  • 8
    • 0000310973 scopus 로고
    • Allostasis: a new paradigm to explain arousal pathology
    • Fisher R., and Reason J. (Eds), John Wiley & Sons
    • Sterling P., and Eyer J. Allostasis: a new paradigm to explain arousal pathology. In: Fisher R., and Reason J. (Eds). Handbook of Life Stress, Cognition and Health (1988), John Wiley & Sons 629-649
    • (1988) Handbook of Life Stress, Cognition and Health , pp. 629-649
    • Sterling, P.1    Eyer, J.2
  • 9
    • 0034142298 scopus 로고    scopus 로고
    • Allostasis and allostatic load: implications for neuropsychopharmacology
    • McEwen B.S. Allostasis and allostatic load: implications for neuropsychopharmacology. Neuropsychopharmacology 22 (2000) 108-124
    • (2000) Neuropsychopharmacology , vol.22 , pp. 108-124
    • McEwen, B.S.1
  • 10
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob G.F., and Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24 (2001) 97-129
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 11
    • 27644548739 scopus 로고    scopus 로고
    • Plasticity of reward neurocircuitry and the 'dark side' of drug addiction
    • Koob G.F., and Le Moal M. Plasticity of reward neurocircuitry and the 'dark side' of drug addiction. Nat. Neurosci. 8 (2005) 1442-1444
    • (2005) Nat. Neurosci. , vol.8 , pp. 1442-1444
    • Koob, G.F.1    Le Moal, M.2
  • 12
    • 33746325472 scopus 로고    scopus 로고
    • Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms
    • Heilig M., and Egli M. Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol. Ther. 111 (2006) 855-876
    • (2006) Pharmacol. Ther. , vol.111 , pp. 855-876
    • Heilig, M.1    Egli, M.2
  • 13
    • 28744441117 scopus 로고    scopus 로고
    • Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism?
    • Egli M. Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism?. Addict. Biol. 10 (2005) 309-319
    • (2005) Addict. Biol. , vol.10 , pp. 309-319
    • Egli, M.1
  • 14
    • 0018583595 scopus 로고
    • Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid diets
    • Rogers J., et al. Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid diets. Behav. Neural Biol. 27 (1979) 466-486
    • (1979) Behav. Neural Biol. , vol.27 , pp. 466-486
    • Rogers, J.1
  • 15
    • 0034008709 scopus 로고    scopus 로고
    • Excessive ethanol drinking following a history of dependence: animal model of allostasis
    • Roberts A.J., et al. Excessive ethanol drinking following a history of dependence: animal model of allostasis. Neuropsychopharmacology 22 (2000) 581-594
    • (2000) Neuropsychopharmacology , vol.22 , pp. 581-594
    • Roberts, A.J.1
  • 16
    • 0036136686 scopus 로고    scopus 로고
    • Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol
    • Rimondini R., et al. Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. FASEB J. 16 (2002) 27-35
    • (2002) FASEB J. , vol.16 , pp. 27-35
    • Rimondini, R.1
  • 17
    • 9244259156 scopus 로고    scopus 로고
    • Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure
    • O'Dell L.E., et al. Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure. Alcohol. Clin. Exp. Res. 28 (2004) 1676-1682
    • (2004) Alcohol. Clin. Exp. Res. , vol.28 , pp. 1676-1682
    • O'Dell, L.E.1
  • 18
    • 27744507998 scopus 로고    scopus 로고
    • Prior multiple ethanol withdrawals enhance stress-induced anxiety-like behavior: inhibition by CRF1- and benzodiazepine-receptor antagonists and a 5-HT1a-receptor agonist
    • Breese G.R., et al. Prior multiple ethanol withdrawals enhance stress-induced anxiety-like behavior: inhibition by CRF1- and benzodiazepine-receptor antagonists and a 5-HT1a-receptor agonist. Neuropsychopharmacology 30 (2005) 1662-1669
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1662-1669
    • Breese, G.R.1
  • 19
    • 16844374405 scopus 로고    scopus 로고
    • Conceptual framework for the etiology of alcoholism: a 'kindling'/stress hypothesis
    • Breese G.R., et al. Conceptual framework for the etiology of alcoholism: a 'kindling'/stress hypothesis. Psychopharmacology (Berl.) 178 (2005) 367-380
    • (2005) Psychopharmacology (Berl.) , vol.178 , pp. 367-380
    • Breese, G.R.1
  • 20
    • 10844243172 scopus 로고    scopus 로고
    • Increased ethanol drinking after repeated chronic ethanol exposure and withdrawal experience in C57BL/6 mice
    • Becker H.C., and Lopez M.F. Increased ethanol drinking after repeated chronic ethanol exposure and withdrawal experience in C57BL/6 mice. Alcohol. Clin. Exp. Res. 28 (2004) 1829-1838
    • (2004) Alcohol. Clin. Exp. Res. , vol.28 , pp. 1829-1838
    • Becker, H.C.1    Lopez, M.F.2
  • 21
    • 0038619059 scopus 로고    scopus 로고
    • Alcohol and withdrawal: from animal research to clinical issues
    • De Witte P., et al. Alcohol and withdrawal: from animal research to clinical issues. Neurosci. Biobehav. Rev. 27 (2003) 189-197
    • (2003) Neurosci. Biobehav. Rev. , vol.27 , pp. 189-197
    • De Witte, P.1
  • 22
    • 0041365389 scopus 로고    scopus 로고
    • A temporal threshold for induction of persistent alcohol preference: behavioral evidence in a rat model of intermittent intoxication
    • Rimondini R., et al. A temporal threshold for induction of persistent alcohol preference: behavioral evidence in a rat model of intermittent intoxication. J. Stud. Alcohol 64 (2003) 445-449
    • (2003) J. Stud. Alcohol , vol.64 , pp. 445-449
    • Rimondini, R.1
  • 23
    • 0019782980 scopus 로고
    • Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin
    • Vale W., et al. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science 213 (1981) 1394-1397
    • (1981) Science , vol.213 , pp. 1394-1397
    • Vale, W.1
  • 24
    • 0020683637 scopus 로고
    • Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study
    • Swanson L.W., et al. Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study. Neuroendocrinology 36 (1983) 165-186
    • (1983) Neuroendocrinology , vol.36 , pp. 165-186
    • Swanson, L.W.1
  • 25
    • 4644285709 scopus 로고    scopus 로고
    • Corticotropin-releasing factor in brain: a role in activation, arousal, and affect regulation
    • Heinrichs S.C., and Koob G.F. Corticotropin-releasing factor in brain: a role in activation, arousal, and affect regulation. J. Pharmacol. Exp. Ther. 311 (2004) 427-440
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 427-440
    • Heinrichs, S.C.1    Koob, G.F.2
  • 26
    • 0036468517 scopus 로고    scopus 로고
    • The CRF peptide family and their receptors: yet more partners discovered
    • Dautzenberg F.M., and Hauger R.L. The CRF peptide family and their receptors: yet more partners discovered. Trends Pharmacol. Sci. 23 (2002) 71-77
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 71-77
    • Dautzenberg, F.M.1    Hauger, R.L.2
  • 27
    • 4043163435 scopus 로고    scopus 로고
    • Getting closer to affective disorders: the role of CRH receptor systems
    • Muller M.B., and Wurst W. Getting closer to affective disorders: the role of CRH receptor systems. Trends Mol. Med. 10 (2004) 409-415
    • (2004) Trends Mol. Med. , vol.10 , pp. 409-415
    • Muller, M.B.1    Wurst, W.2
  • 28
    • 0035985549 scopus 로고    scopus 로고
    • Multiple feedback mechanisms activating corticotropin-releasing hormone system in the brain during stress
    • Makino S., et al. Multiple feedback mechanisms activating corticotropin-releasing hormone system in the brain during stress. Pharmacol. Biochem. Behav. 73 (2002) 147-158
    • (2002) Pharmacol. Biochem. Behav. , vol.73 , pp. 147-158
    • Makino, S.1
  • 29
    • 18344394149 scopus 로고    scopus 로고
    • 1 receptor antagonist. II. Characterization in rodent models of stress-related disorders
    • 1 receptor antagonist. II. Characterization in rodent models of stress-related disorders. J. Pharmacol. Exp. Ther. 301 (2002) 333-345
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 333-345
    • Griebel, G.1
  • 30
    • 18344362026 scopus 로고    scopus 로고
    • 1 receptor antagonist. I. Biochemical and pharmacological characterization
    • 1 receptor antagonist. I. Biochemical and pharmacological characterization. J. Pharmacol. Exp. Ther. 301 (2002) 322-332
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 322-332
    • Gully, D.1
  • 31
    • 0021224839 scopus 로고
    • Chemical anatomy of the brain
    • Hokfelt T., et al. Chemical anatomy of the brain. Science 225 (1984) 1326-1334
    • (1984) Science , vol.225 , pp. 1326-1334
    • Hokfelt, T.1
  • 32
    • 0026022203 scopus 로고
    • CRF antagonist reverses the 'anxiogenic' response to ethanol withdrawal in the rat
    • Baldwin H.A., et al. CRF antagonist reverses the 'anxiogenic' response to ethanol withdrawal in the rat. Psychopharmacology (Berl.) 103 (1991) 227-232
    • (1991) Psychopharmacology (Berl.) , vol.103 , pp. 227-232
    • Baldwin, H.A.1
  • 33
    • 0027415929 scopus 로고
    • Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal
    • Rassnick S., et al. Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal. Brain Res. 605 (1993) 25-32
    • (1993) Brain Res. , vol.605 , pp. 25-32
    • Rassnick, S.1
  • 34
    • 0029117641 scopus 로고
    • Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis
    • Merlo Pich E., et al. Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis. J. Neurosci. 15 (1995) 5439-5447
    • (1995) J. Neurosci. , vol.15 , pp. 5439-5447
    • Merlo Pich, E.1
  • 35
    • 0036204717 scopus 로고    scopus 로고
    • Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake
    • Olive M.F., et al. Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake. Pharmacol. Biochem. Behav. 72 (2002) 213-220
    • (2002) Pharmacol. Biochem. Behav. , vol.72 , pp. 213-220
    • Olive, M.F.1
  • 36
    • 0038022706 scopus 로고    scopus 로고
    • Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence
    • Valdez G.R., et al. Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence. Alcohol 29 (2003) 55-60
    • (2003) Alcohol , vol.29 , pp. 55-60
    • Valdez, G.R.1
  • 37
    • 34447632519 scopus 로고    scopus 로고
    • Sommer, W.H. et al. Up-regulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala Crhr1 expression following a history of dependence. Biol. Psychiatry (in press)
  • 38
    • 0036667843 scopus 로고    scopus 로고
    • Accentuated decrease in social interaction in rats subjected to repeated ethanol withdrawals
    • Overstreet D.H., et al. Accentuated decrease in social interaction in rats subjected to repeated ethanol withdrawals. Alcohol. Clin. Exp. Res. 26 (2002) 1259-1268
    • (2002) Alcohol. Clin. Exp. Res. , vol.26 , pp. 1259-1268
    • Overstreet, D.H.1
  • 39
    • 1242313226 scopus 로고    scopus 로고
    • SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats
    • Knapp D.J., et al. SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats. Alcohol 32 (2004) 101-111
    • (2004) Alcohol , vol.32 , pp. 101-111
    • Knapp, D.J.1
  • 40
    • 1642452720 scopus 로고    scopus 로고
    • Modulation of multiple ethanol withdrawal-induced anxiety-like behavior by CRF and CRF1 receptors
    • Overstreet D.H., et al. Modulation of multiple ethanol withdrawal-induced anxiety-like behavior by CRF and CRF1 receptors. Pharmacol. Biochem. Behav. 77 (2004) 405-413
    • (2004) Pharmacol. Biochem. Behav. , vol.77 , pp. 405-413
    • Overstreet, D.H.1
  • 41
    • 33845201988 scopus 로고    scopus 로고
    • Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats
    • Funk C.K., et al. Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats. Biol. Psychiatry 61 (2007) 78-86
    • (2007) Biol. Psychiatry , vol.61 , pp. 78-86
    • Funk, C.K.1
  • 42
    • 33750931628 scopus 로고    scopus 로고
    • Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats
    • Funk C.K., et al. Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats. J. Neurosci. 26 (2006) 11324-11332
    • (2006) J. Neurosci. , vol.26 , pp. 11324-11332
    • Funk, C.K.1
  • 43
    • 0036798776 scopus 로고    scopus 로고
    • Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor
    • Valdez G.R., et al. Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor. Alcohol. Clin. Exp. Res. 26 (2002) 1494-1501
    • (2002) Alcohol. Clin. Exp. Res. , vol.26 , pp. 1494-1501
    • Valdez, G.R.1
  • 44
    • 33847772007 scopus 로고    scopus 로고
    • 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethy l- imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism
    • Gehlert D.R., et al. 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethy l- imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism. J. Neurosci. 27 (2007) 2718-2726
    • (2007) J. Neurosci. , vol.27 , pp. 2718-2726
    • Gehlert, D.R.1
  • 45
    • 0022742303 scopus 로고
    • Understanding and preventing relapse
    • Brownell K.D., et al. Understanding and preventing relapse. Am. Psychol. 41 (1986) 765-782
    • (1986) Am. Psychol. , vol.41 , pp. 765-782
    • Brownell, K.D.1
  • 46
    • 0038786581 scopus 로고    scopus 로고
    • The reinstatement model of drug relapse: history, methodology and major findings
    • Shaham Y., et al. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl.) 168 (2003) 3-20
    • (2003) Psychopharmacology (Berl.) , vol.168 , pp. 3-20
    • Shaham, Y.1
  • 47
    • 0033948852 scopus 로고    scopus 로고
    • The role of corticotrophin-releasing factor in stress-induced relapse to alcohol-seeking behavior in rats
    • Le A.D., et al. The role of corticotrophin-releasing factor in stress-induced relapse to alcohol-seeking behavior in rats. Psychopharmacology (Berl.) 150 (2000) 317-324
    • (2000) Psychopharmacology (Berl.) , vol.150 , pp. 317-324
    • Le, A.D.1
  • 48
    • 0037107155 scopus 로고    scopus 로고
    • Additive effect of stress and drug cues on reinstatement of ethanol seeking: exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms
    • Liu X., and Weiss F. Additive effect of stress and drug cues on reinstatement of ethanol seeking: exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms. J. Neurosci. 22 (2002) 7856-7861
    • (2002) J. Neurosci. , vol.22 , pp. 7856-7861
    • Liu, X.1    Weiss, F.2
  • 49
    • 20044391431 scopus 로고    scopus 로고
    • Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking
    • Wang B., et al. Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. J. Neurosci. 25 (2005) 5389-5396
    • (2005) J. Neurosci. , vol.25 , pp. 5389-5396
    • Wang, B.1
  • 50
    • 1242341999 scopus 로고    scopus 로고
    • Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior
    • McFarland K., et al. Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior. J. Neurosci. 24 (2004) 1551-1560
    • (2004) J. Neurosci. , vol.24 , pp. 1551-1560
    • McFarland, K.1
  • 51
    • 18844401446 scopus 로고    scopus 로고
    • Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats
    • Le A.D., et al. Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats. Psychopharmacology (Berl.) 179 (2005) 366-373
    • (2005) Psychopharmacology (Berl.) , vol.179 , pp. 366-373
    • Le, A.D.1
  • 52
    • 32344432559 scopus 로고    scopus 로고
    • Effects of environmental and pharmacological stressors on c-fos and corticotropin-releasing factor mRNA in rat brain: relationship to the reinstatement of alcohol seeking
    • Funk D., et al. Effects of environmental and pharmacological stressors on c-fos and corticotropin-releasing factor mRNA in rat brain: relationship to the reinstatement of alcohol seeking. Neuroscience 138 (2006) 235-243
    • (2006) Neuroscience , vol.138 , pp. 235-243
    • Funk, D.1
  • 53
    • 0037107139 scopus 로고    scopus 로고
    • The role of corticotropin-releasing factor in the median raphe nucleus in relapse to alcohol
    • Le A.D., et al. The role of corticotropin-releasing factor in the median raphe nucleus in relapse to alcohol. J. Neurosci. 22 (2002) 7844-7849
    • (2002) J. Neurosci. , vol.22 , pp. 7844-7849
    • Le, A.D.1
  • 54
    • 0035207886 scopus 로고    scopus 로고
    • Changes in levels of regional CRF-like-immunoreactivity and plasma corticosterone during protracted drug withdrawal in dependent rats
    • Zorrilla E.P., et al. Changes in levels of regional CRF-like-immunoreactivity and plasma corticosterone during protracted drug withdrawal in dependent rats. Psychopharmacology (Berl.) 158 (2001) 374-381
    • (2001) Psychopharmacology (Berl.) , vol.158 , pp. 374-381
    • Zorrilla, E.P.1
  • 55
    • 33750055822 scopus 로고    scopus 로고
    • Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism
    • Ciccocioppo R., et al. Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism. Addict. Biol. 11 (2006) 339-355
    • (2006) Addict. Biol. , vol.11 , pp. 339-355
    • Ciccocioppo, R.1
  • 56
    • 33745712822 scopus 로고    scopus 로고
    • Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples
    • Treutlein J., et al. Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. Mol. Psychiatry 11 (2006) 594-602
    • (2006) Mol. Psychiatry , vol.11 , pp. 594-602
    • Treutlein, J.1
  • 57
    • 33750056368 scopus 로고    scopus 로고
    • Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress
    • Hansson A.C., et al. Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 15236-15241
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 15236-15241
    • Hansson, A.C.1
  • 58
    • 33947133287 scopus 로고    scopus 로고
    • Region-specific down regulation of Crhr1 gene expression in alcohol preferring msP rats following ad lib access to alcohol
    • Hansson A.C., et al. Region-specific down regulation of Crhr1 gene expression in alcohol preferring msP rats following ad lib access to alcohol. Addict. Biol. 12 (2007) 30-34
    • (2007) Addict. Biol. , vol.12 , pp. 30-34
    • Hansson, A.C.1
  • 59
    • 0037012953 scopus 로고    scopus 로고
    • Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors
    • Sillaber I., et al. Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors. Science 296 (2002) 931-933
    • (2002) Science , vol.296 , pp. 931-933
    • Sillaber, I.1
  • 60
    • 33646028236 scopus 로고    scopus 로고
    • Chronic smoking and alcoholism change expression of selective genes in the human prefrontal cortex
    • Flatscher-Bader T., and Wilce P.A. Chronic smoking and alcoholism change expression of selective genes in the human prefrontal cortex. Alcohol. Clin. Exp. Res. 30 (2006) 908-915
    • (2006) Alcohol. Clin. Exp. Res. , vol.30 , pp. 908-915
    • Flatscher-Bader, T.1    Wilce, P.A.2
  • 61
    • 13344286293 scopus 로고    scopus 로고
    • Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
    • Rothstein J.D., et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16 (1996) 675-686
    • (1996) Neuron , vol.16 , pp. 675-686
    • Rothstein, J.D.1
  • 62
    • 14044258729 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as novel targets for anxiety and stress disorders
    • Swanson C.J., et al. Metabotropic glutamate receptors as novel targets for anxiety and stress disorders. Nat. Rev. Drug Discov. 4 (2005) 131-144
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 131-144
    • Swanson, C.J.1
  • 63
    • 33644843588 scopus 로고    scopus 로고
    • NPY in alcoholism and psychiatric disorders
    • Thorsell A., et al. NPY in alcoholism and psychiatric disorders. EXS 95 (2006) 183-192
    • (2006) EXS , vol.95 , pp. 183-192
    • Thorsell, A.1
  • 64
    • 12744256723 scopus 로고    scopus 로고
    • Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence
    • Rimondini R., et al. Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence. Neurosci. Lett. 375 (2005) 129-133
    • (2005) Neurosci. Lett. , vol.375 , pp. 129-133
    • Rimondini, R.1
  • 65
    • 17444396438 scopus 로고    scopus 로고
    • Effects of neuropeptide Y and corticotropin-releasing factor on ethanol intake in Wistar rats: interaction with chronic ethanol exposure
    • Thorsell A., et al. Effects of neuropeptide Y and corticotropin-releasing factor on ethanol intake in Wistar rats: interaction with chronic ethanol exposure. Behav. Brain Res. 161 (2005) 133-140
    • (2005) Behav. Brain Res. , vol.161 , pp. 133-140
    • Thorsell, A.1
  • 66
    • 17444406990 scopus 로고    scopus 로고
    • Effects of neuropeptide Y on appetitive and consummatory behaviors associated with alcohol drinking in wistar rats with a history of ethanol exposure
    • Thorsell A., et al. Effects of neuropeptide Y on appetitive and consummatory behaviors associated with alcohol drinking in wistar rats with a history of ethanol exposure. Alcohol. Clin. Exp. Res. 29 (2005) 584-590
    • (2005) Alcohol. Clin. Exp. Res. , vol.29 , pp. 584-590
    • Thorsell, A.1
  • 67
    • 0035089046 scopus 로고    scopus 로고
    • Neuropeptide-Y in the paraventricular nucleus increases ethanol self-administration
    • Kelley S.P., et al. Neuropeptide-Y in the paraventricular nucleus increases ethanol self-administration. Peptides 22 (2001) 515-522
    • (2001) Peptides , vol.22 , pp. 515-522
    • Kelley, S.P.1
  • 68
    • 0028069480 scopus 로고
    • Corticotropin-releasing factor and neuropeptide Y: role in emotional integration
    • Heilig M., et al. Corticotropin-releasing factor and neuropeptide Y: role in emotional integration. Trends Neurosci. 17 (1994) 80-85
    • (1994) Trends Neurosci. , vol.17 , pp. 80-85
    • Heilig, M.1
  • 69
    • 0035023610 scopus 로고    scopus 로고
    • The role of corticotropin-releasing factor in drug addiction
    • Sarnyai Z., et al. The role of corticotropin-releasing factor in drug addiction. Pharmacol. Rev. 53 (2001) 209-243
    • (2001) Pharmacol. Rev. , vol.53 , pp. 209-243
    • Sarnyai, Z.1
  • 70
    • 0033136990 scopus 로고    scopus 로고
    • Reinstatement of alcohol-seeking behavior by drug-associated discriminative stimuli after prolonged extinction in the rat
    • Katner S.N., et al. Reinstatement of alcohol-seeking behavior by drug-associated discriminative stimuli after prolonged extinction in the rat. Neuropsychopharmacology 20 (1999) 471-479
    • (1999) Neuropsychopharmacology , vol.20 , pp. 471-479
    • Katner, S.N.1
  • 71
    • 0031983970 scopus 로고    scopus 로고
    • Reinstatement of alcohol-seeking by priming injections of alcohol and exposure to stress in rats
    • Le A.D., et al. Reinstatement of alcohol-seeking by priming injections of alcohol and exposure to stress in rats. Psychopharmacology (Berl.) 135 (1998) 169-174
    • (1998) Psychopharmacology (Berl.) , vol.135 , pp. 169-174
    • Le, A.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.