메뉴 건너뛰기




Volumn 133, Issue , 2015, Pages 58-68

Extracellular matrix, gap junctions, and retinal vascular homeostasis in diabetic retinopathy

Author keywords

Basement membrane; Collagen type IV; Connexin; Diabetic retinopathy; Extracellular matrix; Fibronectin; Gap junction; Laminin

Indexed keywords

ADVANCED GLYCATION END PRODUCT; AGRIN; ALDEHYDE REDUCTASE; COLLAGEN TYPE 1; COLLAGEN TYPE 4; ENTACTIN; FIBRONECTIN; GELATINASE A; GELATINASE B; GLUCOSE; INTEGRIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LAMININ; MONOCYTE CHEMOTACTIC PROTEIN 1; PERLECAN; PROTEIN KINASE C BETA; PROTEOHEPARAN SULFATE; REACTIVE OXYGEN METABOLITE; TENASCIN; TRANSCRIPTION FACTOR FKHR; TUMOR NECROSIS FACTOR ALPHA; UROKINASE; VASCULOTROPIN;

EID: 84925435002     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2014.08.011     Document Type: Review
Times cited : (35)

References (155)
  • 4
    • 43449109783 scopus 로고    scopus 로고
    • Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy
    • Behl Y., Krothapalli P., Desta T., DiPiazza A., Roy S., Graves D.T. Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy. Am. J. Pathol. 2008, 172:1411-1418.
    • (2008) Am. J. Pathol. , vol.172 , pp. 1411-1418
    • Behl, Y.1    Krothapalli, P.2    Desta, T.3    DiPiazza, A.4    Roy, S.5    Graves, D.T.6
  • 5
    • 64649104157 scopus 로고    scopus 로고
    • FOXO1 plays an important role in enhanced microvascular cell apoptosis and microvascular cell loss in type 1 and type 2 diabetic rats
    • Behl Y., Krothapalli P., Desta T., Roy S., Graves D.T. FOXO1 plays an important role in enhanced microvascular cell apoptosis and microvascular cell loss in type 1 and type 2 diabetic rats. Diabetes 2009, 58:917-925.
    • (2009) Diabetes , vol.58 , pp. 917-925
    • Behl, Y.1    Krothapalli, P.2    Desta, T.3    Roy, S.4    Graves, D.T.5
  • 7
    • 75649090531 scopus 로고    scopus 로고
    • Reduced connexin 43 expression and its effect on the development of vascular lesions in retinas of diabetic mice
    • Bobbie M.W., Roy S., Trudeau K., Munger S.J., Simon A.M., Roy S. Reduced connexin 43 expression and its effect on the development of vascular lesions in retinas of diabetic mice. Investig. Ophthalmol. Vis. Sci. 2010, 51:3758-3763.
    • (2010) Investig. Ophthalmol. Vis. Sci. , vol.51 , pp. 3758-3763
    • Bobbie, M.W.1    Roy, S.2    Trudeau, K.3    Munger, S.J.4    Simon, A.M.5    Roy, S.6
  • 8
    • 0033137070 scopus 로고    scopus 로고
    • Extracellular matrix and integrin signalling: the shape of things to come
    • Boudreau N.J., Jones P.L. Extracellular matrix and integrin signalling: the shape of things to come. Biochem. J. 1999, 339(Pt 3):481-488.
    • (1999) Biochem. J. , vol.339 , pp. 481-488
    • Boudreau, N.J.1    Jones, P.L.2
  • 9
    • 8844274841 scopus 로고    scopus 로고
    • Erytrocyte membrane anionic charge in type 2 diabetic patients with retinopathy
    • Budak Y., Demirci H., Akdogan M., Yavuz D. Erytrocyte membrane anionic charge in type 2 diabetic patients with retinopathy. BMC Ophthalmol. 2004, 4:14.
    • (2004) BMC Ophthalmol. , vol.4 , pp. 14
    • Budak, Y.1    Demirci, H.2    Akdogan, M.3    Yavuz, D.4
  • 12
    • 0037302999 scopus 로고    scopus 로고
    • High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1
    • Chen S., Mukherjee S., Chakraborty C., Chakrabarti S. High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1. Am. J. Physiol. Cell Physiol. 2003, 284:C263-C272.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.284 , pp. C263-C272
    • Chen, S.1    Mukherjee, S.2    Chakraborty, C.3    Chakrabarti, S.4
  • 13
    • 59449094028 scopus 로고    scopus 로고
    • Tight glycemic control regulates fibronectin expression and basement membrane thickening in retinal and glomerular capillaries of diabetic rats
    • Cherian S., Roy S., Pinheiro A., Roy S. Tight glycemic control regulates fibronectin expression and basement membrane thickening in retinal and glomerular capillaries of diabetic rats. Investig. Ophthalmol. Vis. Sci. 2009, 50:943-949.
    • (2009) Investig. Ophthalmol. Vis. Sci. , vol.50 , pp. 943-949
    • Cherian, S.1    Roy, S.2    Pinheiro, A.3    Roy, S.4
  • 14
    • 78650073594 scopus 로고    scopus 로고
    • High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function
    • Chronopoulos A., Tang A., Beglova E., Trackman P.C., Roy S. High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function. Diabetes 2010, 59:3159-3166.
    • (2010) Diabetes , vol.59 , pp. 3159-3166
    • Chronopoulos, A.1    Tang, A.2    Beglova, E.3    Trackman, P.C.4    Roy, S.5
  • 15
    • 79960731769 scopus 로고    scopus 로고
    • High glucose-induced altered basement membrane composition and structure increases trans-endothelial permeability: implications for diabetic retinopathy
    • Chronopoulos A., Trudeau K., Roy S., Huang H., Vinores S.A., Roy S. High glucose-induced altered basement membrane composition and structure increases trans-endothelial permeability: implications for diabetic retinopathy. Curr. Eye Res. 2011, 36:747-753.
    • (2011) Curr. Eye Res. , vol.36 , pp. 747-753
    • Chronopoulos, A.1    Trudeau, K.2    Roy, S.3    Huang, H.4    Vinores, S.A.5    Roy, S.6
  • 16
    • 0030046481 scopus 로고    scopus 로고
    • Interleukin 6 induces the expression of vascular endothelial growth factor
    • Cohen T., Nahari D., Cerem L.W., Neufeld G., Levi B.-Z. Interleukin 6 induces the expression of vascular endothelial growth factor. J.Biol. Chem. 1996, 271:736-741.
    • (1996) J.Biol. Chem. , vol.271 , pp. 736-741
    • Cohen, T.1    Nahari, D.2    Cerem, L.W.3    Neufeld, G.4    Levi, B.-Z.5
  • 17
    • 0035663766 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans in experimental models of diabetes: a role for perlecan in diabetes complications
    • Conde-Knape K. Heparan sulfate proteoglycans in experimental models of diabetes: a role for perlecan in diabetes complications. Diabetes Metab. Res. Rev. 2001, 17:412-421.
    • (2001) Diabetes Metab. Res. Rev. , vol.17 , pp. 412-421
    • Conde-Knape, K.1
  • 18
    • 84878218816 scopus 로고    scopus 로고
    • Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox
    • Costa P.Z., Soares R. Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox. Life Sci. 2013, 92:1037-1045.
    • (2013) Life Sci. , vol.92 , pp. 1037-1045
    • Costa, P.Z.1    Soares, R.2
  • 19
    • 0029931575 scopus 로고    scopus 로고
    • Tenascin: a multifunctional extracellular matrix protein with a restricted distribution in development and disease
    • Crossin K.L. Tenascin: a multifunctional extracellular matrix protein with a restricted distribution in development and disease. J.Cell. Biochem. 1996, 61:592-598.
    • (1996) J.Cell. Biochem. , vol.61 , pp. 592-598
    • Crossin, K.L.1
  • 20
    • 0027483111 scopus 로고
    • Extracellular matrix-stimulated phospholipase activation is mediated by beta 1-integrin
    • Cybulsky A.V., Carbonetto S., Cyr M.D., McTavish A.J., Huang Q. Extracellular matrix-stimulated phospholipase activation is mediated by beta 1-integrin. Am. J. Physiol. 1993, 264:C323-C332.
    • (1993) Am. J. Physiol. , vol.264 , pp. C323-C332
    • Cybulsky, A.V.1    Carbonetto, S.2    Cyr, M.D.3    McTavish, A.J.4    Huang, Q.5
  • 21
    • 17144422114 scopus 로고    scopus 로고
    • Loss of beta 1 integrin function results in upregulation of connexin expression in embryonic stem cell-derived cardiomyocytes
    • Czyz J., Guan K., Zeng Q., Wobus A.M. Loss of beta 1 integrin function results in upregulation of connexin expression in embryonic stem cell-derived cardiomyocytes. Int. J. Dev. Biol. 2005, 49:33-41.
    • (2005) Int. J. Dev. Biol. , vol.49 , pp. 33-41
    • Czyz, J.1    Guan, K.2    Zeng, Q.3    Wobus, A.M.4
  • 22
    • 36248984274 scopus 로고    scopus 로고
    • Roles of gap junctions and connexins in non-neoplastic pathological processes in which cell proliferation is involved
    • Dagli M.L., Hernandez-Blazquez F.J. Roles of gap junctions and connexins in non-neoplastic pathological processes in which cell proliferation is involved. J.Membr. Biol. 2007, 218:79-91.
    • (2007) J.Membr. Biol. , vol.218 , pp. 79-91
    • Dagli, M.L.1    Hernandez-Blazquez, F.J.2
  • 23
    • 0142122287 scopus 로고    scopus 로고
    • Retinal and choroidal angiogenesis: pathophysiology and strategies for inhibition
    • Das A., McGuire P.G. Retinal and choroidal angiogenesis: pathophysiology and strategies for inhibition. Prog. Retin. Eye Res. 2003, 22:721-748.
    • (2003) Prog. Retin. Eye Res. , vol.22 , pp. 721-748
    • Das, A.1    McGuire, P.G.2
  • 24
    • 84871865491 scopus 로고    scopus 로고
    • Muller cell expression of genes implicated in proliferative vitreoretinopathy is influenced by substrate elastic modulus
    • Davis J.T., Wen Q., Janmey P.A., Otteson D.C., Foster W.J. Muller cell expression of genes implicated in proliferative vitreoretinopathy is influenced by substrate elastic modulus. Investig. Ophthalmol. Vis. Sci. 2012, 53:3014-3019.
    • (2012) Investig. Ophthalmol. Vis. Sci. , vol.53 , pp. 3014-3019
    • Davis, J.T.1    Wen, Q.2    Janmey, P.A.3    Otteson, D.C.4    Foster, W.J.5
  • 26
    • 80051597186 scopus 로고    scopus 로고
    • Microvascular modifications in diabetic retinopathy
    • Durham J.T., Herman I.M. Microvascular modifications in diabetic retinopathy. Curr. Diabetes Rep. 2011, 11:253-264.
    • (2011) Curr. Diabetes Rep. , vol.11 , pp. 253-264
    • Durham, J.T.1    Herman, I.M.2
  • 27
  • 28
    • 79959507521 scopus 로고    scopus 로고
    • Extracellular matrix in angiogenesis: dynamic structures with translational potential
    • Eming S.A., Hubbell J.A. Extracellular matrix in angiogenesis: dynamic structures with translational potential. Exp. Dermatol. 2011, 20:605-613.
    • (2011) Exp. Dermatol. , vol.20 , pp. 605-613
    • Eming, S.A.1    Hubbell, J.A.2
  • 29
    • 0024414650 scopus 로고
    • Hyperglycemia and development of glomerular pathology: diabetes compared with galactosemia
    • Engerman R.L., Kern T.S. Hyperglycemia and development of glomerular pathology: diabetes compared with galactosemia. Kidney Int. 1989, 36:41-45.
    • (1989) Kidney Int. , vol.36 , pp. 41-45
    • Engerman, R.L.1    Kern, T.S.2
  • 30
    • 0027271798 scopus 로고
    • Aldose reductase inhibition fails to prevent retinopathy in diabetic and galactosemic dogs
    • Engerman R.L., Kern T.S. Aldose reductase inhibition fails to prevent retinopathy in diabetic and galactosemic dogs. Diabetes 1993, 42:820-825.
    • (1993) Diabetes , vol.42 , pp. 820-825
    • Engerman, R.L.1    Kern, T.S.2
  • 33
    • 3042635556 scopus 로고    scopus 로고
    • High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism
    • Fernandes R., Girao H., Pereira P. High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism. J.Biol. Chem. 2004, 279:27219-27224.
    • (2004) J.Biol. Chem. , vol.279 , pp. 27219-27224
    • Fernandes, R.1    Girao, H.2    Pereira, P.3
  • 34
    • 0141961133 scopus 로고    scopus 로고
    • Inhibition of advanced glycation end-products protects against retinal capillary basement membrane expansion during long-term diabetes
    • Gardiner T.A., Anderson H.R., Stitt A.W. Inhibition of advanced glycation end-products protects against retinal capillary basement membrane expansion during long-term diabetes. J.Pathol. 2003, 201:328-333.
    • (2003) J.Pathol. , vol.201 , pp. 328-333
    • Gardiner, T.A.1    Anderson, H.R.2    Stitt, A.W.3
  • 35
    • 77952468064 scopus 로고    scopus 로고
    • Activation of protein kinase C isoforms and its impact on diabetic complications
    • Geraldes P., King G.L. Activation of protein kinase C isoforms and its impact on diabetic complications. Circ. Res. 2010, 106:1319-1331.
    • (2010) Circ. Res. , vol.106 , pp. 1319-1331
    • Geraldes, P.1    King, G.L.2
  • 36
    • 67650227476 scopus 로고    scopus 로고
    • The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy
    • Gerhardinger C., Dagher Z., Sebastiani P., Park Y.S., Lorenzi M. The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy. Diabetes 2009, 58:1659-1667.
    • (2009) Diabetes , vol.58 , pp. 1659-1667
    • Gerhardinger, C.1    Dagher, Z.2    Sebastiani, P.3    Park, Y.S.4    Lorenzi, M.5
  • 37
    • 60749115085 scopus 로고    scopus 로고
    • Extracellular matrix proteins in epiretinal membranes and in diabetic retinopathy
    • George B., Chen S., Chaudhary V., Gonder J., Chakrabarti S. Extracellular matrix proteins in epiretinal membranes and in diabetic retinopathy. Curr. Eye Res. 2009, 34:134-144.
    • (2009) Curr. Eye Res. , vol.34 , pp. 134-144
    • George, B.1    Chen, S.2    Chaudhary, V.3    Gonder, J.4    Chakrabarti, S.5
  • 38
    • 84925387772 scopus 로고    scopus 로고
    • Computational investigation of pkcbeta inhibitors for the treatment of diabetic retinopathy
    • Gogula S.V., Divakar C., Satyanarayana C., Kumar Y.P., Lavanaya V.S. Computational investigation of pkcbeta inhibitors for the treatment of diabetic retinopathy. Bioinformation 2013, 9:1040-1043.
    • (2013) Bioinformation , vol.9 , pp. 1040-1043
    • Gogula, S.V.1    Divakar, C.2    Satyanarayana, C.3    Kumar, Y.P.4    Lavanaya, V.S.5
  • 39
    • 34247639507 scopus 로고    scopus 로고
    • Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not
    • Goodwin A.M., Kitajewski J., D'Amore P.A. Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not. Growth Factors 2007, 25:25-32.
    • (2007) Growth Factors , vol.25 , pp. 25-32
    • Goodwin, A.M.1    Kitajewski, J.2    D'Amore, P.A.3
  • 41
    • 70350118012 scopus 로고    scopus 로고
    • Changes in cultured endothelial cell glycosaminoglycans under hyperglycemic conditions and the effect of insulin and heparin
    • Han J., Zhang F., Xie J., Linhardt R.J., Hiebert L.M. Changes in cultured endothelial cell glycosaminoglycans under hyperglycemic conditions and the effect of insulin and heparin. Cardiovasc. Diabetol. 2009, 8:46.
    • (2009) Cardiovasc. Diabetol. , vol.8 , pp. 46
    • Han, J.1    Zhang, F.2    Xie, J.3    Linhardt, R.J.4    Hiebert, L.M.5
  • 42
    • 30744434618 scopus 로고    scopus 로고
    • High glucose and angiotensin II increase beta1 integrin and integrin-linked kinase synthesis in cultured mouse podocytes
    • Han S.Y., Kang Y.S., Jee Y.H., Han K.H., Cha D.R., Kang S.W., Han D.S. High glucose and angiotensin II increase beta1 integrin and integrin-linked kinase synthesis in cultured mouse podocytes. Cell Tissue Res. 2006, 323:321-332.
    • (2006) Cell Tissue Res. , vol.323 , pp. 321-332
    • Han, S.Y.1    Kang, Y.S.2    Jee, Y.H.3    Han, K.H.4    Cha, D.R.5    Kang, S.W.6    Han, D.S.7
  • 43
    • 0027064888 scopus 로고
    • Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
    • Houck K.A., Leung D.W., Rowland A.M., Winer J., Ferrara N. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J.Biol. Chem. 1992, 267:26031-26037.
    • (1992) J.Biol. Chem. , vol.267 , pp. 26031-26037
    • Houck, K.A.1    Leung, D.W.2    Rowland, A.M.3    Winer, J.4    Ferrara, N.5
  • 44
    • 84911001721 scopus 로고    scopus 로고
    • Up-regulation of ROS-dependent matrix metalloproteinase-9 from high-glucose-challenged astrocytes contributes to the neuronal apoptosis
    • Hsieh H.L., Chi P.L., Lin C.C., Yang C.C., Yang C.M. Up-regulation of ROS-dependent matrix metalloproteinase-9 from high-glucose-challenged astrocytes contributes to the neuronal apoptosis. Mol. Neurobiol. 2014.
    • (2014) Mol. Neurobiol.
    • Hsieh, H.L.1    Chi, P.L.2    Lin, C.C.3    Yang, C.C.4    Yang, C.M.5
  • 45
    • 0031963247 scopus 로고    scopus 로고
    • Chronology of events accompanying follicular atresia in hypophysectomized ewes. Changes in levels of steroidogenic enzymes, connexin 43, insulin-like growth factor II/mannose 6 phosphate receptor, extracellular matrix components, and matrix metalloproteinases
    • Huet C., Monget P., Pisselet C., Hennequet C., Locatelli A., Monniaux D. Chronology of events accompanying follicular atresia in hypophysectomized ewes. Changes in levels of steroidogenic enzymes, connexin 43, insulin-like growth factor II/mannose 6 phosphate receptor, extracellular matrix components, and matrix metalloproteinases. Biol. Reprod. 1998, 58:175-185.
    • (1998) Biol. Reprod. , vol.58 , pp. 175-185
    • Huet, C.1    Monget, P.2    Pisselet, C.3    Hennequet, C.4    Locatelli, A.5    Monniaux, D.6
  • 47
    • 33748482385 scopus 로고    scopus 로고
    • Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells
    • Isakson B.E., Olsen C.E., Boitano S. Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells. Respir. Res. 2006, 7:105.
    • (2006) Respir. Res. , vol.7 , pp. 105
    • Isakson, B.E.1    Olsen, C.E.2    Boitano, S.3
  • 48
    • 68149131912 scopus 로고    scopus 로고
    • TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations
    • Joussen A.M., Doehmen S., Le M.L., Koizumi K., Radetzky S., Krohne T.U., Poulaki V., Semkova I., Kociok N. TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations. Mol. Vis. 2009, 15:1418-1428.
    • (2009) Mol. Vis. , vol.15 , pp. 1418-1428
    • Joussen, A.M.1    Doehmen, S.2    Le, M.L.3    Koizumi, K.4    Radetzky, S.5    Krohne, T.U.6    Poulaki, V.7    Semkova, I.8    Kociok, N.9
  • 50
    • 84906058512 scopus 로고    scopus 로고
    • Emerging role of advanced glycation-end products (AGEs) in the pathobiology of eye diseases
    • Kandarakis S.A., Piperi C., Topouzis F., Papavassiliou A.G. Emerging role of advanced glycation-end products (AGEs) in the pathobiology of eye diseases. Prog. Retin. Eye Res. 2014, 42:85-102.
    • (2014) Prog. Retin. Eye Res. , vol.42 , pp. 85-102
    • Kandarakis, S.A.1    Piperi, C.2    Topouzis, F.3    Papavassiliou, A.G.4
  • 52
    • 84861059036 scopus 로고    scopus 로고
    • Matrix metalloproteinases in diabetic retinopathy: potential role of MMP-9
    • Kowluru R.A., Zhong Q., Santos J.M. Matrix metalloproteinases in diabetic retinopathy: potential role of MMP-9. Expert Opin. Investig. Drugs 2012, 21:797-805.
    • (2012) Expert Opin. Investig. Drugs , vol.21 , pp. 797-805
    • Kowluru, R.A.1    Zhong, Q.2    Santos, J.M.3
  • 53
    • 0030760729 scopus 로고    scopus 로고
    • Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats
    • Koya D., Jirousek M.R., Lin Y.W., Ishii H., Kuboki K., King G.L. Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats. J.Clin. Investig. 1997, 100:115-126.
    • (1997) J.Clin. Investig. , vol.100 , pp. 115-126
    • Koya, D.1    Jirousek, M.R.2    Lin, Y.W.3    Ishii, H.4    Kuboki, K.5    King, G.L.6
  • 55
    • 3543043820 scopus 로고    scopus 로고
    • Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina
    • Kuiper E.J., Witmer A.N., Klaassen I., Oliver N., Goldschmeding R., Schlingemann R.O. Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina. Br. J. Ophthalmol. 2004, 88:1082-1087.
    • (2004) Br. J. Ophthalmol. , vol.88 , pp. 1082-1087
    • Kuiper, E.J.1    Witmer, A.N.2    Klaassen, I.3    Oliver, N.4    Goldschmeding, R.5    Schlingemann, R.O.6
  • 56
    • 20444470108 scopus 로고    scopus 로고
    • Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas
    • Lakka S.S., Gondi C.S., Dinh D.H., Olivero W.C., Gujrati M., Rao V.H., Sioka C., Rao J.S. Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas. J.Biol. Chem. 2005, 280:21882-21892.
    • (2005) J.Biol. Chem. , vol.280 , pp. 21882-21892
    • Lakka, S.S.1    Gondi, C.S.2    Dinh, D.H.3    Olivero, W.C.4    Gujrati, M.5    Rao, V.H.6    Sioka, C.7    Rao, J.S.8
  • 58
    • 22344437713 scopus 로고    scopus 로고
    • Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors
    • Lee S., Jilani S.M., Nikolova G.V., Carpizo D., Iruela-Arispe M.L. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J.Cell Biol. 2005, 169:681-691.
    • (2005) J.Cell Biol. , vol.169 , pp. 681-691
    • Lee, S.1    Jilani, S.M.2    Nikolova, G.V.3    Carpizo, D.4    Iruela-Arispe, M.L.5
  • 59
    • 77951534756 scopus 로고    scopus 로고
    • Pericyte actomyosin-mediated contraction at the cell-material interface can modulate the microvascular niche
    • Lee S., Zeiger A., Maloney J.M., Kotecki M., Vliet K.J.V., Herman I.M. Pericyte actomyosin-mediated contraction at the cell-material interface can modulate the microvascular niche. J.Phys. Condens. Matter 2010, 22:194115.
    • (2010) J.Phys. Condens. Matter , vol.22 , pp. 194115
    • Lee, S.1    Zeiger, A.2    Maloney, J.M.3    Kotecki, M.4    Vliet, K.J.V.5    Herman, I.M.6
  • 61
    • 84929271744 scopus 로고    scopus 로고
    • Role of fibronectin in normal wound healing
    • Lenselink E.A. Role of fibronectin in normal wound healing. Int. Wound J. 2013.
    • (2013) Int. Wound J.
    • Lenselink, E.A.1
  • 62
    • 62649162866 scopus 로고    scopus 로고
    • High glucose-induced downregulation of connexin 43 expression promotes apoptosis in microvascular endothelial cells
    • Li A.F., Roy S. High glucose-induced downregulation of connexin 43 expression promotes apoptosis in microvascular endothelial cells. Investig. Ophthalmol. Vis. Sci. 2009, 50:1400-1407.
    • (2009) Investig. Ophthalmol. Vis. Sci. , vol.50 , pp. 1400-1407
    • Li, A.F.1    Roy, S.2
  • 63
    • 0345714595 scopus 로고    scopus 로고
    • High glucose alters connexin 43 expression and gap junction intercellular communication activity in retinal pericytes
    • Li A.F., Sato T., Haimovici R., Okamoto T., Roy S. High glucose alters connexin 43 expression and gap junction intercellular communication activity in retinal pericytes. Investig. Ophthalmol. Vis. Sci. 2003, 44:5376-5382.
    • (2003) Investig. Ophthalmol. Vis. Sci. , vol.44 , pp. 5376-5382
    • Li, A.F.1    Sato, T.2    Haimovici, R.3    Okamoto, T.4    Roy, S.5
  • 64
  • 66
    • 77955676274 scopus 로고    scopus 로고
    • Advanced glycation end products down-regulate gap junctions in human hepatoma SKHep 1 cells via the activation of Src-dependent ERK1/2 and JNK/SAPK/AP1 signaling pathways
    • Lin F.L., Chang C.I., Chuang K.P., Wang C.Y., Liu H.J. Advanced glycation end products down-regulate gap junctions in human hepatoma SKHep 1 cells via the activation of Src-dependent ERK1/2 and JNK/SAPK/AP1 signaling pathways. J.Agric. Food Chem. 2010, 58:8636-8642.
    • (2010) J.Agric. Food Chem. , vol.58 , pp. 8636-8642
    • Lin, F.L.1    Chang, C.I.2    Chuang, K.P.3    Wang, C.Y.4    Liu, H.J.5
  • 69
    • 82955213965 scopus 로고    scopus 로고
    • Early inner retinal astrocyte dysfunction during diabetes and development of hypoxia, retinal stress, and neuronal functional loss
    • Ly A., Yee P., Vessey K.A., Phipps J.A., Jobling A.I., Fletcher E.L. Early inner retinal astrocyte dysfunction during diabetes and development of hypoxia, retinal stress, and neuronal functional loss. Investig. Ophthalmol. Vis. Sci. 2011, 52:9316-9326.
    • (2011) Investig. Ophthalmol. Vis. Sci. , vol.52 , pp. 9316-9326
    • Ly, A.1    Yee, P.2    Vessey, K.A.3    Phipps, J.A.4    Jobling, A.I.5    Fletcher, E.L.6
  • 70
    • 0027396853 scopus 로고
    • Ultrastructural changes of extracellular matrices in diabetic nephropathy revealed by high resolution scanning and immunoelectron microscopy
    • Makino H., Yamasaki Y., Haramoto T., Shikata K., Hironaka K., Ota Z., Kanwar Y.S. Ultrastructural changes of extracellular matrices in diabetic nephropathy revealed by high resolution scanning and immunoelectron microscopy. Lab. Investig. J. Tech. Methods Pathol. 1993, 68:45-55.
    • (1993) Lab. Investig. J. Tech. Methods Pathol. , vol.68 , pp. 45-55
    • Makino, H.1    Yamasaki, Y.2    Haramoto, T.3    Shikata, K.4    Hironaka, K.5    Ota, Z.6    Kanwar, Y.S.7
  • 71
    • 84875641085 scopus 로고    scopus 로고
    • High glucose-induced downregulation of connexin 30.2 promotes retinal vascular lesions: implications for diabetic retinopathy
    • Manasson J., Tien T., Moore C., Kumar N.M., Roy S. High glucose-induced downregulation of connexin 30.2 promotes retinal vascular lesions: implications for diabetic retinopathy. Investig. Ophthalmol. Vis. Sci. 2013, 54:2361-2366.
    • (2013) Investig. Ophthalmol. Vis. Sci. , vol.54 , pp. 2361-2366
    • Manasson, J.1    Tien, T.2    Moore, C.3    Kumar, N.M.4    Roy, S.5
  • 72
    • 28844459379 scopus 로고    scopus 로고
    • Fibronectin fibrillogenesis, a cell-mediated matrix assembly process
    • Mao Y., Schwarzbauer J.E. Fibronectin fibrillogenesis, a cell-mediated matrix assembly process. Matrix Biol. J. Int. Soc. Matrix Biol. 2005, 24:389-399.
    • (2005) Matrix Biol. J. Int. Soc. Matrix Biol. , vol.24 , pp. 389-399
    • Mao, Y.1    Schwarzbauer, J.E.2
  • 74
    • 84864842613 scopus 로고    scopus 로고
    • Protein kinase C-mediated regulation of matrix metalloproteinase and tissue inhibitor of metalloproteinase production in a human retinal muller cells
    • Miyata Y., Kase M., Sugita Y., Shimada A., Nagase T., Katsura Y., Kosano H. Protein kinase C-mediated regulation of matrix metalloproteinase and tissue inhibitor of metalloproteinase production in a human retinal muller cells. Curr. Eye Res. 2012, 37:842-849.
    • (2012) Curr. Eye Res. , vol.37 , pp. 842-849
    • Miyata, Y.1    Kase, M.2    Sugita, Y.3    Shimada, A.4    Nagase, T.5    Katsura, Y.6    Kosano, H.7
  • 75
    • 80051736986 scopus 로고    scopus 로고
    • Novel role of mitochondrial matrix metalloproteinase-2 in the development of diabetic retinopathy
    • Mohammad G., Kowluru R.A. Novel role of mitochondrial matrix metalloproteinase-2 in the development of diabetic retinopathy. Investig. Ophthalmol. Vis. Sci. 2011, 52:3832-3841.
    • (2011) Investig. Ophthalmol. Vis. Sci. , vol.52 , pp. 3832-3841
    • Mohammad, G.1    Kowluru, R.A.2
  • 76
    • 84879325249 scopus 로고    scopus 로고
    • The ERK1/2 inhibitor U0126 attenuates diabetes-induced upregulation of MMP-9 and biomarkers of inflammation in the retina
    • Mohammad G., Mairaj Siddiquei M., Imtiaz Nawaz M., Abu El-Asrar A.M. The ERK1/2 inhibitor U0126 attenuates diabetes-induced upregulation of MMP-9 and biomarkers of inflammation in the retina. J.Diabetes Res. 2013, 2013:658548.
    • (2013) J.Diabetes Res. , vol.2013 , pp. 658548
    • Mohammad, G.1    Mairaj Siddiquei, M.2    Imtiaz Nawaz, M.3    Abu El-Asrar, A.M.4
  • 77
    • 84863333566 scopus 로고    scopus 로고
    • Role of matrix metalloproteinase-2 and -9 in the development of diabetic retinopathy
    • Mohammad G., Siddiquei M.M. Role of matrix metalloproteinase-2 and -9 in the development of diabetic retinopathy. J.Ocular Biol. Dis. Inform. 2012, 5:1-8.
    • (2012) J.Ocular Biol. Dis. Inform. , vol.5 , pp. 1-8
    • Mohammad, G.1    Siddiquei, M.M.2
  • 78
    • 84925411033 scopus 로고    scopus 로고
    • Effect of inhibiting high glucose-induced upregulation of ECM on connexin 43 (Cx43) expression in retinal endothelial cells
    • ARVO 2011 Conference, E-Abstract 3554
    • Moon J., Knack H.P., Roy S. Effect of inhibiting high glucose-induced upregulation of ECM on connexin 43 (Cx43) expression in retinal endothelial cells. Investig. Ophthalmol. Vis. Sci. 2011, 52. ARVO 2011 Conference, E-Abstract 3554.
    • (2011) Investig. Ophthalmol. Vis. Sci. , vol.52
    • Moon, J.1    Knack, H.P.2    Roy, S.3
  • 79
    • 33846142148 scopus 로고    scopus 로고
    • Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration
    • Mori R., Power K.T., Wang C.M., Martin P., Becker D.L. Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration. J.Cell Sci. 2006, 119:5193-5203.
    • (2006) J.Cell Sci. , vol.119 , pp. 5193-5203
    • Mori, R.1    Power, K.T.2    Wang, C.M.3    Martin, P.4    Becker, D.L.5
  • 80
    • 84904330674 scopus 로고    scopus 로고
    • High glucose alters cx43 expression and gap junction intercellular communication in retinal muller cells: promotes muller cell and pericyte apoptosis
    • Muto T., Tien T., Kim D., Sarthy V.P., Roy S. High glucose alters cx43 expression and gap junction intercellular communication in retinal muller cells: promotes muller cell and pericyte apoptosis. Investig. Ophthalmol. Vis. Sci. 2014, 55:4327-4337.
    • (2014) Investig. Ophthalmol. Vis. Sci. , vol.55 , pp. 4327-4337
    • Muto, T.1    Tien, T.2    Kim, D.3    Sarthy, V.P.4    Roy, S.5
  • 81
    • 14744281815 scopus 로고    scopus 로고
    • Arandomised, placebo controlled clinical trial of the aldose reductase inhibitor CT-112 as management of corneal epithelial disorders in diabetic patients
    • Nakahara M., Miyata K., Otani S., Miyai T., Nejima R., Yamagami S., Amano S. Arandomised, placebo controlled clinical trial of the aldose reductase inhibitor CT-112 as management of corneal epithelial disorders in diabetic patients. Br. J. Ophthalmol. 2005, 89:266-268.
    • (2005) Br. J. Ophthalmol. , vol.89 , pp. 266-268
    • Nakahara, M.1    Miyata, K.2    Otani, S.3    Miyai, T.4    Nejima, R.5    Yamagami, S.6    Amano, S.7
  • 83
    • 44649186476 scopus 로고    scopus 로고
    • Dexamethasone inhibits high glucose-, TNF-α-, and IL-1β-induced secretion of inflammatory and angiogenic mediators from retinal microvascular pericytes
    • Nehmé A., Edelman J. Dexamethasone inhibits high glucose-, TNF-α-, and IL-1β-induced secretion of inflammatory and angiogenic mediators from retinal microvascular pericytes. Investig. Ophthalmol. Vis. Sci. 2008, 49:2030-2038.
    • (2008) Investig. Ophthalmol. Vis. Sci. , vol.49 , pp. 2030-2038
    • Nehmé, A.1    Edelman, J.2
  • 84
    • 84878426785 scopus 로고    scopus 로고
    • Age-dependent alteration of intraocular soluble heparan sulfate levels and its implications for proliferative diabetic retinopathy
    • Nishiguchi K.M., Ushida H., Tomida D., Kachi S., Kondo M., Terasaki H. Age-dependent alteration of intraocular soluble heparan sulfate levels and its implications for proliferative diabetic retinopathy. Mol. Vis. 2013, 19:1125-1131.
    • (2013) Mol. Vis. , vol.19 , pp. 1125-1131
    • Nishiguchi, K.M.1    Ushida, H.2    Tomida, D.3    Kachi, S.4    Kondo, M.5    Terasaki, H.6
  • 87
    • 0023585264 scopus 로고
    • Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells
    • Orlidge A., D'Amore P.A. Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells. J.Cell Biol. 1987, 105:1455-1462.
    • (1987) J.Cell Biol. , vol.105 , pp. 1455-1462
    • Orlidge, A.1    D'Amore, P.A.2
  • 88
    • 20544441038 scopus 로고    scopus 로고
    • SiRNA strategy against overexpression of extracellular matrix in diabetic retinopathy
    • Oshitari T., Brown D., Roy S. SiRNA strategy against overexpression of extracellular matrix in diabetic retinopathy. Exp. Eye Res. 2005, 81:32-37.
    • (2005) Exp. Eye Res. , vol.81 , pp. 32-37
    • Oshitari, T.1    Brown, D.2    Roy, S.3
  • 89
    • 33644756703 scopus 로고    scopus 로고
    • Effect of combined antisense oligonucleotides against high-glucose- and diabetes-induced overexpression of extracellular matrix components and increased vascular permeability
    • Oshitari T., Polewski P., Chadda M., Li A.F., Sato T., Roy S. Effect of combined antisense oligonucleotides against high-glucose- and diabetes-induced overexpression of extracellular matrix components and increased vascular permeability. Diabetes 2006, 55:86-92.
    • (2006) Diabetes , vol.55 , pp. 86-92
    • Oshitari, T.1    Polewski, P.2    Chadda, M.3    Li, A.F.4    Sato, T.5    Roy, S.6
  • 90
    • 84883169988 scopus 로고    scopus 로고
    • Inflammatory cytokine-specific alterations in retinal endothelial cell function
    • Palenski T.L., Sorenson C.M., Sheibani N. Inflammatory cytokine-specific alterations in retinal endothelial cell function. Microvasc. Res. 2013, 89:57-69.
    • (2013) Microvasc. Res. , vol.89 , pp. 57-69
    • Palenski, T.L.1    Sorenson, C.M.2    Sheibani, N.3
  • 91
    • 84908327798 scopus 로고    scopus 로고
    • Serum glycated albumin predicts the progression of diabetic retinopathy-a five year retrospective longitudinal study
    • Pan J., Li Q., Zhang L., Jia L., Tang J., Bao Y., Jia W. Serum glycated albumin predicts the progression of diabetic retinopathy-a five year retrospective longitudinal study. J.Diabetes Complicat. 2014.
    • (2014) J.Diabetes Complicat.
    • Pan, J.1    Li, Q.2    Zhang, L.3    Jia, L.4    Tang, J.5    Bao, Y.6    Jia, W.7
  • 92
    • 0037107551 scopus 로고    scopus 로고
    • Fibronectin at a glance
    • Pankov R., Yamada K.M. Fibronectin at a glance. J.Cell Sci. 2002, 115:3861-3863.
    • (2002) J.Cell Sci. , vol.115 , pp. 3861-3863
    • Pankov, R.1    Yamada, K.M.2
  • 93
    • 84925385229 scopus 로고    scopus 로고
    • High glucose-induced upregulation of collagen type IV and laminin expression regulates connexin 43 expression in microvascular endothelial cells
    • Abstract # 0838-P
    • Pinheiro A., Roy S. High glucose-induced upregulation of collagen type IV and laminin expression regulates connexin 43 expression in microvascular endothelial cells. 67th American Diabetes Association Conference. Chicago, IL 2007, Abstract # 0838-P.
    • (2007) 67th American Diabetes Association Conference. Chicago, IL
    • Pinheiro, A.1    Roy, S.2
  • 95
    • 0030976894 scopus 로고    scopus 로고
    • Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect
    • Plouët J., Moro F., Bertagnolli S., Coldeboeuf N., Mazarguil H., Clamens S., Bayard F. Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect. J.Biol. Chem. 1997, 272:13390-13396.
    • (1997) J.Biol. Chem. , vol.272 , pp. 13390-13396
    • Plouët, J.1    Moro, F.2    Bertagnolli, S.3    Coldeboeuf, N.4    Mazarguil, H.5    Clamens, S.6    Bayard, F.7
  • 96
    • 77954176749 scopus 로고    scopus 로고
    • Alterations of the Wnt/beta-catenin pathway and its target genes for the N- and C-terminal domains of parathyroid hormone-related protein in bone from diabetic mice
    • Portal-Nunez S., Lozano D., de Castro L.F., de Gortazar A.R., Nogues X., Esbrit P. Alterations of the Wnt/beta-catenin pathway and its target genes for the N- and C-terminal domains of parathyroid hormone-related protein in bone from diabetic mice. FEBS Lett. 2010, 584:3095-3100.
    • (2010) FEBS Lett. , vol.584 , pp. 3095-3100
    • Portal-Nunez, S.1    Lozano, D.2    de Castro, L.F.3    de Gortazar, A.R.4    Nogues, X.5    Esbrit, P.6
  • 97
    • 0023753260 scopus 로고
    • Increased steady-state levels of laminin B1 mRNA in kidneys of long-term streptozotocin-diabetic rats. No effect of an aldose reductase inhibitor
    • Poulsom R., Kurkinen M., Prockop D.J., Boot-Handford R.P. Increased steady-state levels of laminin B1 mRNA in kidneys of long-term streptozotocin-diabetic rats. No effect of an aldose reductase inhibitor. J.Biol. Chem. 1988, 263:10072-10076.
    • (1988) J.Biol. Chem. , vol.263 , pp. 10072-10076
    • Poulsom, R.1    Kurkinen, M.2    Prockop, D.J.3    Boot-Handford, R.P.4
  • 101
    • 84925385228 scopus 로고    scopus 로고
    • Proteinases and integrins in ocular angiogenesis
    • Lippincott Williams & Wilkins, Philadelpha, PA, T.F. Arup Das (Ed.)
    • Rangasamy S., Ljubimov A., Roy S., McGuire P., Das A. Proteinases and integrins in ocular angiogenesis. Therapy for Ocular Angiogenesis 2011, 52-63. Lippincott Williams & Wilkins, Philadelpha, PA. T.F. Arup Das (Ed.).
    • (2011) Therapy for Ocular Angiogenesis , pp. 52-63
    • Rangasamy, S.1    Ljubimov, A.2    Roy, S.3    McGuire, P.4    Das, A.5
  • 102
    • 0027491025 scopus 로고
    • Integrin overexpression induced by high glucose and by human diabetes: potential pathway to cell dysfunction in diabetic microangiopathy
    • Roth T., Podesta F., Stepp M.A., Boeri D., Lorenzi M. Integrin overexpression induced by high glucose and by human diabetes: potential pathway to cell dysfunction in diabetic microangiopathy. Proc. Natl. Acad. Sci. U. S. A. 1993, 90:9640-9644.
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 9640-9644
    • Roth, T.1    Podesta, F.2    Stepp, M.A.3    Boeri, D.4    Lorenzi, M.5
  • 103
    • 33344466450 scopus 로고    scopus 로고
    • Making the cut: protease-mediated regulation of angiogenesis
    • Roy R., Zhang B., Moses M.A. Making the cut: protease-mediated regulation of angiogenesis. Exp. Cell Res. 2006, 312:608-622.
    • (2006) Exp. Cell Res. , vol.312 , pp. 608-622
    • Roy, R.1    Zhang, B.2    Moses, M.A.3
  • 104
    • 0030019991 scopus 로고    scopus 로고
    • Fibronectin overexpression in retinal microvessels of patients with diabetes
    • Roy S., Cagliero E., Lorenzi M. Fibronectin overexpression in retinal microvessels of patients with diabetes. Investig. Ophthalmol. Vis. Sci. 1996, 37:258-266.
    • (1996) Investig. Ophthalmol. Vis. Sci. , vol.37 , pp. 258-266
    • Roy, S.1    Cagliero, E.2    Lorenzi, M.3
  • 105
    • 78649731494 scopus 로고    scopus 로고
    • Vascular basement membrane thickening in diabetic retinopathy
    • Roy S., Ha J., Trudeau K., Beglova E. Vascular basement membrane thickening in diabetic retinopathy. Curr. Eye Res. 2010, 35:1045-1056.
    • (2010) Curr. Eye Res. , vol.35 , pp. 1045-1056
    • Roy, S.1    Ha, J.2    Trudeau, K.3    Beglova, E.4
  • 106
    • 0028120769 scopus 로고
    • Increased expression of basement membrane collagen in human diabetic retinopathy
    • Roy S., Maiello M., Lorenzi M. Increased expression of basement membrane collagen in human diabetic retinopathy. J.Clin. Investig. 1994, 93:438-442.
    • (1994) J.Clin. Investig. , vol.93 , pp. 438-442
    • Roy, S.1    Maiello, M.2    Lorenzi, M.3
  • 107
    • 83055178335 scopus 로고    scopus 로고
    • Along-term siRNA strategy regulates fibronectin overexpression and improves vascular lesions in retinas of diabetic rats
    • Roy S., Nasser S., Yee M., Graves D.T., Roy S. Along-term siRNA strategy regulates fibronectin overexpression and improves vascular lesions in retinas of diabetic rats. Mol. Vis. 2011, 17:3166-3174.
    • (2011) Mol. Vis. , vol.17 , pp. 3166-3174
    • Roy, S.1    Nasser, S.2    Yee, M.3    Graves, D.T.4    Roy, S.5
  • 108
    • 0030759092 scopus 로고    scopus 로고
    • Proliferative effect of high glucose is modulated by antisense oligonucleotides against fibronectin in rat endothelial cells
    • Roy S., Roth T. Proliferative effect of high glucose is modulated by antisense oligonucleotides against fibronectin in rat endothelial cells. Diabetologia 1997, 40:1011-1017.
    • (1997) Diabetologia , vol.40 , pp. 1011-1017
    • Roy, S.1    Roth, T.2
  • 109
    • 0037407314 scopus 로고    scopus 로고
    • Downregulation of fibronectin overexpression reduces basement membrane thickening and vascular lesions in retinas of galactose-fed rats
    • Roy S., Sato T., Paryani G., Kao R. Downregulation of fibronectin overexpression reduces basement membrane thickening and vascular lesions in retinas of galactose-fed rats. Diabetes 2003, 52:1229-1234.
    • (2003) Diabetes , vol.52 , pp. 1229-1234
    • Roy, S.1    Sato, T.2    Paryani, G.3    Kao, R.4
  • 110
    • 2442686835 scopus 로고    scopus 로고
    • Radial migration of developing microglial cells in quail retina: a confocal microscopy study
    • Sanchez-Lopez A., Cuadros M.A., Calvente R., Tassi M., Marin-Teva J.L., Navascues J. Radial migration of developing microglial cells in quail retina: a confocal microscopy study. Glia 2004, 46:261-273.
    • (2004) Glia , vol.46 , pp. 261-273
    • Sanchez-Lopez, A.1    Cuadros, M.A.2    Calvente, R.3    Tassi, M.4    Marin-Teva, J.L.5    Navascues, J.6
  • 112
    • 0036319123 scopus 로고    scopus 로고
    • Downregulation of connexin 43 expression by high glucose reduces gap junction activity in microvascular endothelial cells
    • Sato T., Haimovici R., Kao R., Li A.F., Roy S. Downregulation of connexin 43 expression by high glucose reduces gap junction activity in microvascular endothelial cells. Diabetes 2002, 51:1565-1571.
    • (2002) Diabetes , vol.51 , pp. 1565-1571
    • Sato, T.1    Haimovici, R.2    Kao, R.3    Li, A.F.4    Roy, S.5
  • 113
    • 0035694836 scopus 로고    scopus 로고
    • Antisense oligonucleotides modulate high glucose-induced laminin overexpression and cell proliferation: a potential for therapeutic application in diabetic microangiopathy
    • Sato T., Paryani G., Kao R.S., Li A.F., Roy S. Antisense oligonucleotides modulate high glucose-induced laminin overexpression and cell proliferation: a potential for therapeutic application in diabetic microangiopathy. Antisense Nucleic Acid Drug Dev. 2001, 11:387-394.
    • (2001) Antisense Nucleic Acid Drug Dev. , vol.11 , pp. 387-394
    • Sato, T.1    Paryani, G.2    Kao, R.S.3    Li, A.F.4    Roy, S.5
  • 114
  • 115
    • 84877828190 scopus 로고    scopus 로고
    • Treatment with hydrogen sulfide alleviates streptozotocin-induced diabetic retinopathy in rats
    • Si Y.F., Wang J., Guan J., Zhou L., Sheng Y., Zhao J. Treatment with hydrogen sulfide alleviates streptozotocin-induced diabetic retinopathy in rats. Br. J. Pharmacol. 2013, 169:619-631.
    • (2013) Br. J. Pharmacol. , vol.169 , pp. 619-631
    • Si, Y.F.1    Wang, J.2    Guan, J.3    Zhou, L.4    Sheng, Y.5    Zhao, J.6
  • 116
    • 33646527453 scopus 로고    scopus 로고
    • Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy
    • Simo R., Carrasco E., Garcia-Ramirez M., Hernandez C. Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy. Curr. Diabetes Rev. 2006, 2:71-98.
    • (2006) Curr. Diabetes Rev. , vol.2 , pp. 71-98
    • Simo, R.1    Carrasco, E.2    Garcia-Ramirez, M.3    Hernandez, C.4
  • 117
    • 84908035956 scopus 로고    scopus 로고
    • Thioredoxin interacting protein (TXNIP) and pathogenesis of diabetic retinopathy
    • Singh L.P. Thioredoxin interacting protein (TXNIP) and pathogenesis of diabetic retinopathy. J.Clin. Exp. Ophthalmol. 2013, 4.
    • (2013) J.Clin. Exp. Ophthalmol. , vol.4
    • Singh, L.P.1
  • 118
    • 0025073693 scopus 로고
    • Arandomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy. Sorbinil Retinopathy Trial Research Group
    • Sorbinil-Retinopathy-Trial-Group
    • Arandomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy. Sorbinil Retinopathy Trial Research Group. Arch. Ophthalmol. 1990, 108:1234-1244. Sorbinil-Retinopathy-Trial-Group.
    • (1990) Arch. Ophthalmol. , vol.108 , pp. 1234-1244
  • 120
    • 0028906824 scopus 로고
    • Effect of high glucose on formation of extracellular matrix components by cultured rat heart endothelial cells
    • Spiro M.J., He Q., D'Autilia M.L. Effect of high glucose on formation of extracellular matrix components by cultured rat heart endothelial cells. Diabetologia 1995, 38:430-436.
    • (1995) Diabetologia , vol.38 , pp. 430-436
    • Spiro, M.J.1    He, Q.2    D'Autilia, M.L.3
  • 123
    • 0028123510 scopus 로고
    • Diabetic retinopathy: quantitative variation in capillary basement membrane thickening in arterial or venous environments
    • Stitt A.W., Anderson H.R., Gardiner T.A., Archer D.B. Diabetic retinopathy: quantitative variation in capillary basement membrane thickening in arterial or venous environments. Br. J. Ophthalmol. 1994, 78:133-137.
    • (1994) Br. J. Ophthalmol. , vol.78 , pp. 133-137
    • Stitt, A.W.1    Anderson, H.R.2    Gardiner, T.A.3    Archer, D.B.4
  • 124
    • 0037163051 scopus 로고    scopus 로고
    • Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes
    • Sundaramoorthy M., Meiyappan M., Todd P., Hudson B.G. Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes. J.Biol. Chem. 2002, 277:31142-31153.
    • (2002) J.Biol. Chem. , vol.277 , pp. 31142-31153
    • Sundaramoorthy, M.1    Meiyappan, M.2    Todd, P.3    Hudson, B.G.4
  • 126
    • 0348109425 scopus 로고    scopus 로고
    • Reactive oxygen species in the vasculature: molecular and cellular mechanisms
    • Taniyama Y., Griendling K.K. Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 2003, 42:1075-1081.
    • (2003) Hypertension , vol.42 , pp. 1075-1081
    • Taniyama, Y.1    Griendling, K.K.2
  • 127
    • 0036172425 scopus 로고    scopus 로고
    • Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells
    • Taraboletti G., D'Ascenzo S., Borsotti P., Giavazzi R., Pavan A., Dolo V. Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells. Am. J. Pathol. 2002, 160:673-680.
    • (2002) Am. J. Pathol. , vol.160 , pp. 673-680
    • Taraboletti, G.1    D'Ascenzo, S.2    Borsotti, P.3    Giavazzi, R.4    Pavan, A.5    Dolo, V.6
  • 128
    • 84878893830 scopus 로고    scopus 로고
    • Human pericyte-endothelial cell interactions in co-culture models mimicking the diabetic retinal microvascular environment
    • Tarallo S., Beltramo E., Berrone E., Porta M. Human pericyte-endothelial cell interactions in co-culture models mimicking the diabetic retinal microvascular environment. Acta Diabetol. 2012, 49(Suppl.1):S141-S151.
    • (2012) Acta Diabetol. , vol.49 , Issue.SUPPL.1 , pp. S141-S151
    • Tarallo, S.1    Beltramo, E.2    Berrone, E.3    Porta, M.4
  • 130
    • 84885031592 scopus 로고    scopus 로고
    • Effects of high glucose-induced Cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells
    • Tien T., Barrette K.F., Chronopoulos A., Roy S. Effects of high glucose-induced Cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells. Investig. Ophthalmol. Vis. Sci. 2013, 54:6518-6525.
    • (2013) Investig. Ophthalmol. Vis. Sci. , vol.54 , pp. 6518-6525
    • Tien, T.1    Barrette, K.F.2    Chronopoulos, A.3    Roy, S.4
  • 131
    • 84901944233 scopus 로고    scopus 로고
    • Downregulation of Connexin 43 promotes vascular cell loss and excess permeability associated with the development of vascular lesions in the diabetic retina
    • Tien T., Muto T., Barrette K., Challyandra L., Roy S. Downregulation of Connexin 43 promotes vascular cell loss and excess permeability associated with the development of vascular lesions in the diabetic retina. Mol. Vis. 2014, 20:732-741.
    • (2014) Mol. Vis. , vol.20 , pp. 732-741
    • Tien, T.1    Muto, T.2    Barrette, K.3    Challyandra, L.4    Roy, S.5
  • 133
    • 0026375229 scopus 로고
    • Beta 1-integrin-mediated neuronal responses to extracellular matrix proteins
    • Tomaselli K.J. Beta 1-integrin-mediated neuronal responses to extracellular matrix proteins. Ann. N. Y. Acad. Sci. 1991, 633:100-104.
    • (1991) Ann. N. Y. Acad. Sci. , vol.633 , pp. 100-104
    • Tomaselli, K.J.1
  • 135
    • 84871875952 scopus 로고    scopus 로고
    • Downregulation of mitochondrial connexin 43 by high glucose triggers mitochondrial shape change and cytochrome C release in retinal endothelial cells
    • Trudeau K., Muto T., Roy S. Downregulation of mitochondrial connexin 43 by high glucose triggers mitochondrial shape change and cytochrome C release in retinal endothelial cells. Investig. Ophthalmol. Vis. Sci. 2012, 53:6675-6681.
    • (2012) Investig. Ophthalmol. Vis. Sci. , vol.53 , pp. 6675-6681
    • Trudeau, K.1    Muto, T.2    Roy, S.3
  • 136
    • 80053513862 scopus 로고    scopus 로고
    • Fenofibric acid reduces fibronectin and collagen type IV overexpression in human retinal pigment epithelial cells grown in conditions mimicking the diabetic milieu: functional implications in retinal permeability
    • Trudeau K., Roy S., Guo W., Hernandez C., Villarroel M., Simo R., Roy S. Fenofibric acid reduces fibronectin and collagen type IV overexpression in human retinal pigment epithelial cells grown in conditions mimicking the diabetic milieu: functional implications in retinal permeability. Investig. Ophthalmol. Vis. Sci. 2011, 52:6348-6354.
    • (2011) Investig. Ophthalmol. Vis. Sci. , vol.52 , pp. 6348-6354
    • Trudeau, K.1    Roy, S.2    Guo, W.3    Hernandez, C.4    Villarroel, M.5    Simo, R.6    Roy, S.7
  • 137
    • 0037899247 scopus 로고    scopus 로고
    • Microvascular basement membranes in diabetes mellitus
    • Tsilibary E.C. Microvascular basement membranes in diabetes mellitus. J.Pathol. 2003, 200:537-546.
    • (2003) J.Pathol. , vol.200 , pp. 537-546
    • Tsilibary, E.C.1
  • 138
    • 32444434289 scopus 로고    scopus 로고
    • Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes
    • Uemura A., Kusuhara S., Wiegand S.J., Yu R.T., Nishikawa S. Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes. J.Clin. Investig. 2006, 116:369-377.
    • (2006) J.Clin. Investig. , vol.116 , pp. 369-377
    • Uemura, A.1    Kusuhara, S.2    Wiegand, S.J.3    Yu, R.T.4    Nishikawa, S.5
  • 139
    • 84899860943 scopus 로고    scopus 로고
    • Acell-regulatory mechanism involving feedback between contraction and tissue formation guides wound healing progression
    • Valero C., Javierre E., Garcia-Aznar J.M., Gomez-Benito M.J. Acell-regulatory mechanism involving feedback between contraction and tissue formation guides wound healing progression. PloS One 2014, 9:e92774.
    • (2014) PloS One , vol.9 , pp. e92774
    • Valero, C.1    Javierre, E.2    Garcia-Aznar, J.M.3    Gomez-Benito, M.J.4
  • 141
    • 77955636443 scopus 로고    scopus 로고
    • Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model
    • Vempati P., Mac Gabhann F., Popel A.S. Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model. PloS One 2010, 5:e11860.
    • (2010) PloS One , vol.5 , pp. e11860
    • Vempati, P.1    Mac Gabhann, F.2    Popel, A.S.3
  • 142
    • 0036177427 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation
    • Verrecchia F., Mauviel A. Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation. J.Investig. Dermatol. 2002, 118:211-215.
    • (2002) J.Investig. Dermatol. , vol.118 , pp. 211-215
    • Verrecchia, F.1    Mauviel, A.2
  • 143
    • 33749661874 scopus 로고    scopus 로고
    • Connexin 32 and 43 gap junctions differentially modulate tenocyte response to cyclic mechanical load
    • Waggett A.D., Benjamin M., Ralphs J.R. Connexin 32 and 43 gap junctions differentially modulate tenocyte response to cyclic mechanical load. Eur. J. Cell Biol. 2006, 85:1145-1154.
    • (2006) Eur. J. Cell Biol. , vol.85 , pp. 1145-1154
    • Waggett, A.D.1    Benjamin, M.2    Ralphs, J.R.3
  • 145
    • 0035669720 scopus 로고    scopus 로고
    • Protein kinase C and the development of diabetic vascular complications
    • Way K.J., Katai N., King G.L. Protein kinase C and the development of diabetic vascular complications. Diabet. Med. J. Br. Diabet. Assoc. 2001, 18:945-959.
    • (2001) Diabet. Med. J. Br. Diabet. Assoc. , vol.18 , pp. 945-959
    • Way, K.J.1    Katai, N.2    King, G.L.3
  • 146
    • 8444245596 scopus 로고    scopus 로고
    • Connexins and cell signaling in development and disease
    • Wei C.J., Xu X., Lo C.W. Connexins and cell signaling in development and disease. Annu. Rev. Cell Dev. Biol. 2004, 20:811-838.
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 811-838
    • Wei, C.J.1    Xu, X.2    Lo, C.W.3
  • 147
    • 0037373094 scopus 로고    scopus 로고
    • CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells
    • Weston B.S., Wahab N.A., Mason R.M. CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells. J.Am. Soc. Nephrol. JASN 2003, 14:601-610.
    • (2003) J.Am. Soc. Nephrol. JASN , vol.14 , pp. 601-610
    • Weston, B.S.1    Wahab, N.A.2    Mason, R.M.3
  • 148
    • 84860861068 scopus 로고    scopus 로고
    • Inhibition of connective tissue growth factor by small interfering ribonucleic acid prevents increase in extracellular matrix molecules in a rodent model of diabetic retinopathy
    • Winkler J.L., Kedees M.H., Guz Y., Teitelman G. Inhibition of connective tissue growth factor by small interfering ribonucleic acid prevents increase in extracellular matrix molecules in a rodent model of diabetic retinopathy. Mol. Vis. 2012, 18:874-886.
    • (2012) Mol. Vis. , vol.18 , pp. 874-886
    • Winkler, J.L.1    Kedees, M.H.2    Guz, Y.3    Teitelman, G.4
  • 150
    • 84873347252 scopus 로고    scopus 로고
    • ERK5 Regulates glucose-induced increased fibronectin production in the endothelial cells and in the retina in diabetes
    • Wu Y., Feng B., Chen S., Chakrabarti S. ERK5 Regulates glucose-induced increased fibronectin production in the endothelial cells and in the retina in diabetes. Invest. Ophthalmol. Vis. Sci. 2012, 53:8405-8413.
    • (2012) Invest. Ophthalmol. Vis. Sci. , vol.53 , pp. 8405-8413
    • Wu, Y.1    Feng, B.2    Chen, S.3    Chakrabarti, S.4
  • 152
    • 84860907513 scopus 로고    scopus 로고
    • CTGFsiRNA ameliorates retinal cells apoptosis in streptozotocin-induced diabetic rats
    • Yang H.W., Chen X.L., Liu Z.L., Liu J., Bu L.M. CTGFsiRNA ameliorates retinal cells apoptosis in streptozotocin-induced diabetic rats. Int. J. Ophthalmol. 2010, 3:120-124.
    • (2010) Int. J. Ophthalmol. , vol.3 , pp. 120-124
    • Yang, H.W.1    Chen, X.L.2    Liu, Z.L.3    Liu, J.4    Bu, L.M.5
  • 154
    • 84886853090 scopus 로고    scopus 로고
    • Cyr61 induces the expression of monocyte chemoattractant protein-1 via the integrin alphanubeta3, FAK, PI3K/Akt, and NF-kappaB pathways in retinal vascular endothelial cells
    • You J.J., Yang C.H., Yang C.M., Chen M.S. Cyr61 induces the expression of monocyte chemoattractant protein-1 via the integrin alphanubeta3, FAK, PI3K/Akt, and NF-kappaB pathways in retinal vascular endothelial cells. Cell. Signal. 2014, 26:133-140.
    • (2014) Cell. Signal. , vol.26 , pp. 133-140
    • You, J.J.1    Yang, C.H.2    Yang, C.M.3    Chen, M.S.4
  • 155
    • 65649130436 scopus 로고    scopus 로고
    • Developmental and pathogenic mechanisms of basement membrane assembly
    • Yurchenco P.D., Patton B.L. Developmental and pathogenic mechanisms of basement membrane assembly. Curr. Pharm. Des. 2009, 15:1277-1294.
    • (2009) Curr. Pharm. Des. , vol.15 , pp. 1277-1294
    • Yurchenco, P.D.1    Patton, B.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.