Ultrastructural features of retinal capillary basement membrane thickening in diabetic swine

Ultrastructural Pathology

Volumn 34, Issue 1, 2010, Pages 35-41

  Lee, Song Eun ^a   Ma, Wanchao ^a   Rattigan, Eileen M ^a   Aleshin, Alexey ^a   Chen, Liqun ^a   Johnson, Lynne L ^a   D'Agati, Vivette D ^a   Schmidt, Ann Marie ^a   Barile, Gaetano R ^a  

^a Columbia University ^*  (United States)

Author keywords

Basement membrane; Diabetes; Diabetic retinopathy; Electron microscopy; Swine; Ultrastructure

Indexed keywords

STREPTOZOCIN;

ANIMAL; ARTICLE; BASEMENT MEMBRANE; BLOOD; BODY WEIGHT; CAPILLARY; CHEMICALLY INDUCED DISORDER; DIABETIC RETINOPATHY; DISEASE MODEL; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; FOOD DEPRIVATION; GLUCOSE BLOOD LEVEL; IMAGE PROCESSING; MALE; PATHOLOGY; RETINA BLOOD VESSEL; SWINE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALS; BASEMENT MEMBRANE; BLOOD GLUCOSE; BODY WEIGHT; CAPILLARIES; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; FOOD DEPRIVATION; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; RETINAL VESSELS; STREPTOZOCIN; SWINE;

ANIMALIA; SUIDAE;

EID: 75149124822     PISSN: 01913123     EISSN: 15210758     Source Type: Journal    
DOI: 10.3109/01913120903308583     Document Type: Article

References (25)

1. Frank RN. Diabetic retinopathy. N Engl J Med. 2004;350:48-58.
2. Ashton N. Vascular basement membrane changes in diabetic retinopathy. Montgomery lecture, 1973. Br J Ophthalmol. 1974;58:344-366.
3. Bloodworth JM Jr. Diabetic microangiopathy. Diabetes. 1963;12:99-114.
4. Robison WG Jr, Kador PF, Kinoshita JH. Retinal capillaries: basement membrane thickening by galactosemia prevented with aldose reductase inhibitor. Science. 1983;221:1177-1179.
5. Toussaint D, Dustin P. Electron microscopy of normal and diabetic retinal capillaries. Arch Ophthalmol. 1963;70;96-108.
6. Engerman RL, Bloodworth JM Jr. Experimental Diabetic Retinopathy in Dogs. Arch Ophthalmol. 1965;73:205-210.
7. Tso MO, Kurosawa A, Benhamou E, et al. Microangiopathic retinopathy in experimental diabetic monkeys. Trans Am Ophthalmol Soc. 1988;86:389-421.
8. Bresnick GH, Engerman R, Davis MD, et al. Patterns of ischemia in diabetic retinopathy. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976;81:694-709.
9. Douglas WR. Of pigs and men and research: a review of applications and analogies of the pig, Sus scrofa, in human medical research. Space Life Sci. 1972;3:226-234.
10. Gerrity RG, Natarajan R, Nadler JL, et al. Diabetes-induced accelerated atherosclerosis in swine. Diabetes. 2001;50:1654-1665.
11. McKenzie JE. Swine as a model in cardiovascular research. In: Tumbleson ME, Schook LB, eds. Advances in Swine in Biomedical Research. New York: Springer-Verlag; 1996:7-18.
12. Anderson HR, Stitt AW, Gardiner TA, et al. Diabetic retinopathy: morphometric analysis of basement membrane thickening of capillaries in different retinal layers within arterial and venous environments. Br J Ophthalmol. 1995;79:1120-1123.
13. Fischer F, Gartner J. Morphometric analysis of basal laminae in rats with long-term streptozotocin diabetes L, II: retinal capillaries. Exp Eye Res. 1983;37:55-64.
14. Cuthbertson RA, Hopper JL, Mandel TE. Difference in effect of cultured fetal pancreas transplants on retinal and renal capillary basement membrane thickness in diabetic mice. Transplantation. 1989;48:218-223.
15. Feit-Leichman RA, Kinouchi R, Takeda M, et al. Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes. Invest Ophthalmol Vis Sci. 2005;46:4281-4287.
16. Hainsworth DP, Katz ML, Sanders DA, et al. Retinal capillary basement membrane thickening in a porcine model of diabetes mellitus. Comp Med. 2002;52:523-529.
17. Higgins PJ, Garlick RL, Bunn HF. Glycosylated hemoglobin in human and animal red cells. Role of glucose permeability. Diabetes. 1982;31:743-748.
18. Rendell M, Stephen PM, Paulsen R, et al. An interspecies comparison of normal levels of glycosylated hemoglobin and glycosylated albumin. Comp Biochem Physiol B. 1985;81:819-922.
19. Kurtz SM, Feldman JD. Experimental studies on the formation of the glomerular basement membrane. J Ultrastruct Res. 1962;6:19-27.
20. Leuenberger PM, Beauchemin ML, Babel J. Experimental diabetic retinopathy. Arch Ophtalmol Rev Gen Ophtalmol. 1974;34:289-302.
21. Hori S, Mukai N. Ultrastructural lesions of retinal pericapillary Muller cells in streptozotocin-induced diabetic rats. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1980;213:1-9. (Pubitemid 10133690)
22. Frank RN, Keirn RJ, Kennedy A, et al. Galactose-induced retinal capillary basement membrane thickening: prevention by Sorbinil. Invest Ophthalmol Vis Sci. 1983;24:1519-1524.
23. Robison WG Jr, Kador PF, Akagi Y, et al. Prevention of basement membrane thickening in retinal capillaries by a novel inhibitor of aldose reductase, tolrestat. Diabetes. 1986;35:295-299.
24. Vracko R. Basal lamina layering in diabetes mellitus: evidence for accelerated rate of cell death and cell regeneration. Diabetes. 1974;23:94-104.
25. Bloodworth JM Jr, Gutgesell HP Jr, Engerman RL. Retinal vasculature of the pig: light and electron microscope studies. Exp Eye Res. 1965;4:174-178.