메뉴 건너뛰기




Volumn 52, Issue 9, 2011, Pages 6348-6354

Fenofibric acid reduces fibronectin and collagen type IV overexpression in human retinal pigment epithelial cells grown in conditions mimicking the diabetic milieu: Functional implications in retinal permeability

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 1; COLLAGEN TYPE 4; FENOFIBRIC ACID; FIBRONECTIN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GLUCOSE; INTERLEUKIN 1BETA; PROTEIN ZO1; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); DEXTRAN; DRUG DERIVATIVE; FENOFIBRATE; FLUORESCEIN ISOTHIOCYANATE; HYPOCHOLESTEROLEMIC AGENT; MEMBRANE PROTEIN; MESSENGER RNA; PHOSPHOPROTEIN; ZONULA OCCLUDENS-1 PROTEIN;

EID: 80053513862     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7282     Document Type: Article
Times cited : (60)

References (40)
  • 1
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
    • Keech A, Simes RJ, Barter P, et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet. 2005;366:1849-1861.
    • (2005) Lancet. , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3
  • 2
    • 36049001784 scopus 로고    scopus 로고
    • Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): A randomised controlled trial
    • Keech AC, Mitchell P, Summanen PA, et al Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial. Lancet. 2007;370:1687-1697.
    • (2007) Lancet. , vol.370 , pp. 1687-1697
    • Keech, A.C.1    Mitchell, P.2    Summanen, P.A.3
  • 3
    • 77954654472 scopus 로고    scopus 로고
    • Effects of medical therapies on retinopathy progression in type 2 diabetes
    • Chew EY, Ambrosius WT, Davis MD, et al. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med. 2010;363:233-244.
    • (2010) N Engl J Med. , vol.363 , pp. 233-244
    • Chew, E.Y.1    Ambrosius, W.T.2    Davis, M.D.3
  • 4
    • 36048985669 scopus 로고    scopus 로고
    • Fenofibrate for diabetic retinopathy
    • Simo R, Hernandez C. Fenofibrate for diabetic retinopathy. Lancet. 2007;370:1667-1668.
    • (2007) Lancet. , vol.370 , pp. 1667-1668
    • Simo, R.1    Hernandez, C.2
  • 5
    • 0029941224 scopus 로고    scopus 로고
    • Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic, dense LDL profile in combined hyperlipidemia
    • Guerin M, Bruckert E, Dolphin PJ, Turpin G, Chapman MJ. Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic, dense LDL profile in combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 1996;16:763-772.
    • (1996) Arterioscler Thromb Vasc Biol. , vol.16 , pp. 763-772
    • Guerin, M.1    Bruckert, E.2    Dolphin, P.J.3    Turpin, G.4    Chapman, M.J.5
  • 6
    • 19944379835 scopus 로고    scopus 로고
    • Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia
    • Koh KK, Han SH, Quon MJ, Yeal Ahn J, Shin EK. Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia. Diabetes Care. 2005;28:1419-1424.
    • (2005) Diabetes Care. , vol.28 , pp. 1419-1424
    • Koh, K.K.1    Han, S.H.2    Quon, M.J.3    Yeal Ahn, J.4    Shin, E.K.5
  • 7
    • 0033377677 scopus 로고    scopus 로고
    • The effect of fenofibrate on insulin sensitivity and plasma lipid profile in nondiabetic males with low high density lipoprotein/dyslipidaemic syndrome
    • Yong QW, Thavintharan S, Cheng A, Chew LS. The effect of fenofibrate on insulin sensitivity and plasma lipid profile in nondiabetic males with low high density lipoprotein/dyslipidaemic syndrome. Ann Acad Med Singapore. 1999;28:778-782.
    • (1999) Ann Acad Med Singapore. , vol.28 , pp. 778-782
    • Yong, Q.W.1    Thavintharan, S.2    Cheng, A.3    Chew, L.S.4
  • 8
    • 52949107622 scopus 로고    scopus 로고
    • Treatment of hyperlipidaemia with fenofibrate and related fibrates
    • Filippatos T, Milionis HJ. Treatment of hyperlipidaemia with fenofibrate and related fibrates. Expert Opin Investig Drugs. 2008;17: 1599-1614.
    • (2008) Expert Opin Investig Drugs. , vol.17 , pp. 1599-1614
    • Filippatos, T.1    Milionis, H.J.2
  • 9
    • 0034468677 scopus 로고    scopus 로고
    • New insights into the pathophysiology of diabetic retinopathy: Potential cell-specific therapeutic targets
    • Gardner TW, Antonetti DA, Barber AJ, LaNoue KF, Nakamura M. New insights into the pathophysiology of diabetic retinopathy: potential cell-specific therapeutic targets. Diabetes Technol Ther. 2000;2:601-608.
    • (2000) Diabetes Technol Ther. , vol.2 , pp. 601-608
    • Gardner, T.W.1    Antonetti, D.A.2    Barber, A.J.3    LaNoue, K.F.4    Nakamura, M.5
  • 10
    • 59449094028 scopus 로고    scopus 로고
    • Tight glycemic control regulates fibronectin expression and basement membrane thickening in retinal and glomerular capillaries of diabetic rats
    • Cherian S, Roy S, Pinheiro A. Tight glycemic control regulates fibronectin expression and basement membrane thickening in retinal and glomerular capillaries of diabetic rats. Invest Ophthalmol Vis Sci. 2009;50:943-949.
    • (2009) Invest Ophthalmol Vis Sci. , vol.50 , pp. 943-949
    • Cherian, S.1    Roy, S.2    Pinheiro, A.3
  • 11
    • 33644756703 scopus 로고    scopus 로고
    • Effect of combined antisense oligonucleotides against high-glucose-and diabetes-induced overexpression of extracellular matrix components and increased vascular permeability
    • Oshitari T, Polewski P, Chadda M, Li AF, Sato T, Roy S. Effect of combined antisense oligonucleotides against high-glucose-and diabetes-induced overexpression of extracellular matrix components and increased vascular permeability. Diabetes. 2006;55:86-92.
    • (2006) Diabetes. , vol.55 , pp. 86-92
    • Oshitari, T.1    Polewski, P.2    Chadda, M.3    Li, A.F.4    Sato, T.5    Roy, S.6
  • 12
    • 0029977817 scopus 로고    scopus 로고
    • Early biosynthetic changes in the diabetic-like retinopathy of galactose-fed rats
    • Roy S, Lorenzi M. Early biosynthetic changes in the diabetic-like retinopathy of galactose-fed rats. Diabetologia. 1996;39:735-738.
    • (1996) Diabetologia. , vol.39 , pp. 735-738
    • Roy, S.1    Lorenzi, M.2
  • 13
    • 0034112260 scopus 로고    scopus 로고
    • Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats
    • Evans T, Deng DX, Chen S, Chakrabarti S. Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats. Diabetes. 2000;49: 662-666.
    • (2000) Diabetes. , vol.49 , pp. 662-666
    • Evans, T.1    Deng, D.X.2    Chen, S.3    Chakrabarti, S.4
  • 16
    • 33646527453 scopus 로고    scopus 로고
    • Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy
    • Simo R, Carrasco E, Garcia-Ramirez M, Hernandez C. Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy. Curr Diabetes Rev. 2006;2:71-98.
    • (2006) Curr Diabetes Rev. , vol.2 , pp. 71-98
    • Simo, R.1    Carrasco, E.2    Garcia-Ramirez, M.3    Hernandez, C.4
  • 18
    • 77953170750 scopus 로고    scopus 로고
    • The retinal pigment epithelium: Something more than a constituent of the blood-retinal barrier-implications for the pathogenesis of diabetic retinopathy
    • Simo R, Villarroel M, Corraliza L, Hernandez C, Garcia-Ramirez M. The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier-implications for the pathogenesis of diabetic retinopathy. J Biomed Biotechnol. 2010;2010:190724.
    • (2010) J Biomed Biotechnol. , vol.2010 , pp. 190724
    • Simo, R.1    Villarroel, M.2    Corraliza, L.3    Hernandez, C.4    Garcia-Ramirez, M.5
  • 19
    • 0021833301 scopus 로고
    • Fibronectin of the chorioretinal interface in the monkey: Immunohistochemical and immunoelectron microscopic studies
    • Ishibashi T, Kohno T, Sorgente N, Patterson R, Ryan SJ. Fibronectin of the chorioretinal interface in the monkey: immunohistochemical and immunoelectron microscopic studies. Graefes Arch Clin Exp Ophthalmol. 1985;223:158-163.
    • (1985) Graefes Arch Clin Exp Ophthalmol. , vol.223 , pp. 158-163
    • Ishibashi, T.1    Kohno, T.2    Sorgente, N.3    Patterson, R.4    Ryan, S.J.5
  • 21
    • 3142581890 scopus 로고    scopus 로고
    • Ultrastructural aging of the RPE-Bruch's membrane-choriocapillaris complex in the D-galactose-treated mouse
    • Ida H, Ishibashi K, Reiser K, Hjelmeland LM, Handa JT. Ultrastructural aging of the RPE-Bruch's membrane-choriocapillaris complex in the D-galactose-treated mouse. Invest Ophthalmol Vis Sci. 2004; 45:2348-2354.
    • (2004) Invest Ophthalmol Vis Sci. , vol.45 , pp. 2348-2354
    • Ida, H.1    Ishibashi, K.2    Reiser, K.3    Hjelmeland, L.M.4    Handa, J.T.5
  • 22
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A. 1979;76:4350-4354.
    • (1979) Proc Natl Acad Sci U S A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 23
    • 0042283930 scopus 로고    scopus 로고
    • Interleukin-1beta and barrier function of retinal pigment epithelial cells (ARPE-19): Aberrant expression of junctional complex molecules
    • Abe T, Sugano E, Saigo Y, Tamai M. Interleukin-1beta and barrier function of retinal pigment epithelial cells (ARPE-19): aberrant expression of junctional complex molecules. Invest Ophthalmol Vis Sci. 2003;44:4097-4104.
    • (2003) Invest Ophthalmol Vis Sci. , vol.44 , pp. 4097-4104
    • Abe, T.1    Sugano, E.2    Saigo, Y.3    Tamai, M.4
  • 24
    • 80052518269 scopus 로고    scopus 로고
    • Fenofibric acid prevents retinal pigment epithelium disruption induced by interleukin-1beta by suppressing AMP-activated protein kinase (AMPK) activation
    • Villarroel M, Garcia-Ramirez M, Corraliza L, Hernandez C, Simo R. Fenofibric acid prevents retinal pigment epithelium disruption induced by interleukin-1beta by suppressing AMP-activated protein kinase (AMPK) activation. Diabetologia. 2011;54(6):1543-1553.
    • (2011) Diabetologia. , vol.54 , Issue.6 , pp. 1543-1553
    • Villarroel, M.1    Garcia-Ramirez, M.2    Corraliza, L.3    Hernandez, C.4    Simo, R.5
  • 25
    • 0037407314 scopus 로고    scopus 로고
    • Downregulation of fibronectin overexpression reduces basement membrane thickening and vascular lesions in retinas of galactose-fed rats
    • Roy S, Sato T, Paryani G, Kao R. Downregulation of fibronectin overexpression reduces basement membrane thickening and vascular lesions in retinas of galactose-fed rats. Diabetes. 2003;52: 1229-1234.
    • (2003) Diabetes. , vol.52 , pp. 1229-1234
    • Roy, S.1    Sato, T.2    Paryani, G.3    Kao, R.4
  • 26
    • 0023388436 scopus 로고
    • Characterization of retinal pigment epithelial cells cultured on microporous filters
    • Heth CA, Yankauckas MA, Adamian M, Edwards RB. Characterization of retinal pigment epithelial cells cultured on microporous filters. Curr Eye Res. 1987;6:1007-1019.
    • (1987) Curr Eye Res. , vol.6 , pp. 1007-1019
    • Heth, C.A.1    Yankauckas, M.A.2    Adamian, M.3    Edwards, R.B.4
  • 27
    • 41149099068 scopus 로고    scopus 로고
    • Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy
    • Kern TS. Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Exp Diabetes Res. 2007;2007:95-103.
    • (2007) Exp Diabetes Res. , vol.2007 , pp. 95-103
    • Kern, T.S.1
  • 28
    • 52649142151 scopus 로고    scopus 로고
    • Novel potential mechanisms for diabetic macular edema: Leveraging new investigational approaches
    • Gardner TW, Antonetti DA. Novel potential mechanisms for diabetic macular edema: leveraging new investigational approaches. Curr Diab Rep. 2008;8:263-269.
    • (2008) Curr Diab Rep. , vol.8 , pp. 263-269
    • Gardner, T.W.1    Antonetti, D.A.2
  • 29
    • 0030949355 scopus 로고    scopus 로고
    • Serum inhibits tight junction formation in cultured pigment epithelial cells
    • Chang CW, Ye L, Defoe DM, Caldwell RB. Serum inhibits tight junction formation in cultured pigment epithelial cells. Invest Ophthalmol Vis Sci. 1997;38:1082-1093.
    • (1997) Invest Ophthalmol Vis Sci. , vol.38 , pp. 1082-1093
    • Chang, C.W.1    Ye, L.2    Defoe, D.M.3    Caldwell, R.B.4
  • 30
    • 0036324946 scopus 로고    scopus 로고
    • Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor
    • Jin M, Barron E, He S, Ryan SJ, Hinton DR. Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor. Invest Ophthalmol Vis Sci. 2002;43:2782-2790.
    • (2002) Invest Ophthalmol Vis Sci. , vol.43 , pp. 2782-2790
    • Jin, M.1    Barron, E.2    He, S.3    Ryan, S.J.4    Hinton, D.R.5
  • 31
    • 34648843667 scopus 로고    scopus 로고
    • Placental growth factor-1 and epithelial haemato-retinal barrier breakdown: Potential implication in the pathogenesis of diabetic retinopathy
    • Miyamoto N, de Kozak Y, Jeanny JC, et al. Placental growth factor-1 and epithelial haemato-retinal barrier breakdown: potential implication in the pathogenesis of diabetic retinopathy. Diabetologia. 2007;50:461-470.
    • (2007) Diabetologia. , vol.50 , pp. 461-470
    • Miyamoto, N.1    de Kozak, Y.2    Jeanny, J.C.3
  • 33
    • 33845546564 scopus 로고    scopus 로고
    • Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy
    • Demircan N, Safran BG, Soylu M, Ozcan AA, Sizmaz S. Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy. Eye. 2006;20: 1366-1369.
    • (2006) Eye. , vol.20 , pp. 1366-1369
    • Demircan, N.1    Safran, B.G.2    Soylu, M.3    Ozcan, A.A.4    Sizmaz, S.5
  • 34
    • 33847048626 scopus 로고    scopus 로고
    • Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia
    • Vincent JA, Mohr S. Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia. Diabetes. 2007;56:224-230.
    • (2007) Diabetes. , vol.56 , pp. 224-230
    • Vincent, J.A.1    Mohr, S.2
  • 35
    • 0031459263 scopus 로고    scopus 로고
    • Proliferation and extracellular matrix production by human infragenicular smooth muscle cells in response to interleukin-1 beta
    • discussion 1007-1008
    • Forsyth EA, Aly HM, Neville RF, Sidawy AN. Proliferation and extracellular matrix production by human infragenicular smooth muscle cells in response to interleukin-1 beta. J Vasc Surg. 1997; 26:1002-1007; discussion 1007-1008.
    • (1997) J Vasc Surg. , vol.26 , pp. 1002-1007
    • Forsyth, E.A.1    Aly, H.M.2    Neville, R.F.3    Sidawy, A.N.4
  • 36
    • 0033238014 scopus 로고    scopus 로고
    • Interleukin-1beta stimulates the production of extracellular matrix in cultured human peritoneal mesothelial cells
    • Yang WS, Kim BS, Lee SK, Park JS, Kim SB. Interleukin-1beta stimulates the production of extracellular matrix in cultured human peritoneal mesothelial cells. Perit Dial Int. 1999;19:211-220.
    • (1999) Perit Dial Int. , vol.19 , pp. 211-220
    • Yang, W.S.1    Kim, B.S.2    Lee, S.K.3    Park, J.S.4    Kim, S.B.5
  • 37
    • 33646156170 scopus 로고    scopus 로고
    • Renoprotective effects of fenofibrate in diabetic rats are achieved by suppressing kidney plasminogen activator inhibitor-1
    • Chen LL, Zhang JY, Wang BP. Renoprotective effects of fenofibrate in diabetic rats are achieved by suppressing kidney plasminogen activator inhibitor-1. Vascul Pharmacol. 2006;44:309-315.
    • (2006) Vascul Pharmacol. , vol.44 , pp. 309-315
    • Chen, L.L.1    Zhang, J.Y.2    Wang, B.P.3
  • 38
    • 77950626579 scopus 로고    scopus 로고
    • PPARα agonist fenofibrate protects the kidney from hypertensive injury in spontaneously hypertensive rats via inhibition of oxidative stress and MAPK activity
    • Hou X, Shen YH, Li C, et al. PPARα agonist fenofibrate protects the kidney from hypertensive injury in spontaneously hypertensive rats via inhibition of oxidative stress and MAPK activity. Biochem Biophys Res Commun. 2010;394:653-659.
    • (2010) Biochem Biophys Res Commun. , vol.394 , pp. 653-659
    • Hou, X.1    Shen, Y.H.2    Li, C.3
  • 39
    • 34247880263 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload
    • Duhaney TA, Cui L, Rude MK, et al. Peroxisome proliferatoractivated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload. Hypertension. 2007;49:1084-1094.
    • (2007) Hypertension. , vol.49 , pp. 1084-1094
    • Duhaney, T.A.1    Cui, L.2    Rude, M.K.3
  • 40
    • 34247108235 scopus 로고    scopus 로고
    • Fenofibrate regulates retinal endothelial cell survival through the AMPK signal transduction pathway
    • Kim J, Ahn JH, Kim JH, et al. Fenofibrate regulates retinal endothelial cell survival through the AMPK signal transduction pathway. Exp Eye Res. 2007;84:886-893.
    • (2007) Exp Eye Res. , vol.84 , pp. 886-893
    • Kim, J.1    Ahn, J.H.2    Kim, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.