Taste receptors in the gut tune the release of peptides in response to nutrients

Peptides

Volumn 66, Issue , 2015, Pages 9-12

  Depoortere, Inge ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Endocrine cells; Nutrient sensing; Taste receptors

Indexed keywords

ACESULFAME; CARBOHYDRATE; CHOLECYSTOKININ; CHOLECYSTOKININ RECEPTOR; GHRELIN; GHRELIN RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; INCRETIN; MOTILIN; NEUROTENSIN; PEPTIDE; SODIUM GLUCOSE COTRANSPORTER 1; SUCRALOSE; SWEETENING AGENT;

ARTICLE; BITTER TASTE; FOOD INTAKE; HUMAN; HUNGER; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN SECRETION; SALTINESS; SATIETY; SOUR TASTE; SWEETNESS; TASTE BUD; BIOLOGICAL MODEL; ENTEROENDOCRINE CELL; METABOLISM; PHYSIOLOGY; TASTE;

ENTEROENDOCRINE CELLS; HUMANS; MODELS, BIOLOGICAL; PEPTIDES; TASTE;

EID: 84925070697     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2015.01.013     Document Type: Editorial

References (47)

1. J. Chandrashekar, M.A. Hoon, N.J. Ryba, and C.S. Zuker The receptors and cells for mammalian taste Nature 444 2006 288 294
2. C.D. Dotson, M.C. Geraedts, and S.D. Munger Peptide regulators of peripheral taste function Semin Cell Dev Biol 24 2013 232 239
3. Y.K. Shin, B. Martin, E. Golden, C.D. Dotson, S. Maudsley, and W. Kim et al. Modulation of taste sensitivity by GLP-1 signaling J Neurochem 106 2008 455 463
4. X.J. Zhang, Y.Q. Wang, Y. Long, L. Wang, Y. Li, and F.B. Gao et al. Alteration of sweet taste in high-fat diet induced obese rats after 4 weeks treatment with exenatide Peptides 47 2013 115 123
5. I. Depoortere Taste receptors of the gut: emerging roles in health and disease Gut 63 2014 179 190
6. S. Janssen, and I. Depoortere Nutrient sensing in the gut: new roads to therapeutics? Trends Endocrinol Metab 24 2013 92 100
7. N. Hass, K. Schwarzenbacher, and H. Breer T1R3 is expressed in brush cells and ghrelin-producing cells of murine stomach Cell Tissue Res 339 2010 493 504
8. S. Janssen, J. Laermans, H. Iwakura, J. Tack, and I. Depoortere Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein PLoS ONE 7 2012 e40168
9. S. Janssen, J. Laermans, P.J. Verhulst, T. Thijs, J. Tack, and I. Depoortere Bitter taste receptors and alpha-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying Proc Natl Acad Sci U S A 108 2011 2094 2099
10. M.S. Engelstoft, W.M. Park, I. Sakata, L.V. Kristensen, A.S. Husted, and S. Osborne-Lawrence et al. Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells Mol Metab 2 2013 376 392
11. M.K. Nohr, M.H. Pedersen, A. Gille, K.L. Egerod, M.S. Engelstoft, and A.S. Husted et al. GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes Endocrinology 154 2013 3552 3564
12. D.C. Haid, C. Jordan-Biegger, P. Widmayer, and H. Breer Receptors responsive to protein breakdown products in g-cells and d-cells of mouse, swine and human Front Physiol 3 2012 65
13. T. Tanaka, S. Katsuma, T. Adachi, T.A. Koshimizu, A. Hirasawa, and G. Tsujimoto Free fatty acids induce cholecystokinin secretion through GPR120 Naunyn Schmiedebergs Arch Pharmacol 377 2008 523 527
14. A.P. Liou, X. Lu, Y. Sei, X. Zhao, S. Pechhold, and R.J. Carrero et al. The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin Gastroenterology 140 2011 903 912
15. A.P. Liou, Y. Sei, X. Zhao, J. Feng, X. Lu, and C. Thomas et al. The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to l-phenylalanine in acutely isolated intestinal I cells Am J Physiol Gastrointest Liver Physiol 300 2011 G538 G546
16. K. Daly, M. Al-Rammahi, A. Moran, M. Marcello, Y. Ninomiya, and S.P. Shirazi-Beechey Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion Am J Physiol Gastrointest Liver Physiol 304 2013 G271 G282
17. A.G. Sykaras, C. Demenis, R.M. Case, J.T. McLaughlin, and C.P. Smith Duodenal enteroendocrine I-cells contain mRNA transcripts encoding key endocannabinoid and fatty acid receptors PLoS ONE 7 2012 e42373
18. S. Edfalk, P. Steneberg, and H. Edlund Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion Diabetes 57 2008 2280 2287
19. A. Hirasawa, K. Tsumaya, T. Awaji, S. Katsuma, T. Adachi, and M. Yamada et al. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120 Nat Med 11 2005 90 94
20. M. Oya, T. Kitaguchi, R. Pais, F. Reimann, F. Gribble, and T. Tsuboi The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag cells J Biol Chem 288 2013 4513 4521
21. R.E. Steinert, A.C. Gerspach, H. Gutmann, L. Asarian, J. Drewe, and C. Beglinger The functional involvement of gut-expressed sweet taste receptors in glucose-stimulated secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) Clin Nutr 30 2011 524 532
22. H.J. Jang, Z. Kokrashvili, M.J. Theodorakis, O.D. Carlson, B.J. Kim, and J. Zhou et al. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1 Proc Natl Acad Sci U S A 104 2007 15069 15074
23. M.C. Geraedts, T. Takahashi, S. Vigues, M.L. Markwardt, A. Nkobena, and R.E. Cockerham et al. Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery Am J Physiol Endocrinol Metab 303 2012 E464 E474
24. A.C. Gerspach, R.E. Steinert, L. Schonenberger, A. Graber-Maier, and C. Beglinger The role of the gut sweet taste receptor in regulating GLP-1, PYY, and CCK release in humans Am J Physiol Endocrinol Metab 301 2011 E317 E325
25. F.M. Gribble, L. Williams, A.K. Simpson, and F. Reimann A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line Diabetes 52 2003 1147 1154
26. F. Reimann, A.M. Habib, G. Tolhurst, H.E. Parker, G.J. Rogers, and F.M. Gribble Glucose sensing in L cells: a primary cell study Cell Metab 8 2008 532 539
27. V. Gorboulev, A. Schurmann, V. Vallon, H. Kipp, A. Jaschke, and D. Klessen et al. Na(+)-d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion Diabetes 61 2012 187 196
28. J. Ma, M. Bellon, J.M. Wishart, R. Young, L.A. Blackshaw, and K.L. Jones et al. Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects Am J Physiol Gastrointest Liver Physiol 296 2009 G735 G739
29. J. Ma, J. Chang, H.L. Checklin, R.L. Young, K.L. Jones, and M. Horowitz et al. Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects Br J Nutr 104 2010 803 806
30. R.E. Steinert, F. Frey, A. Topfer, J. Drewe, and C. Beglinger Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides Br J Nutr 105 2011 1320 1328
31. R.J. Brown, M. Walter, and K.I. Rother Effects of diet soda on gut hormones in youths with diabetes Diabetes Care 35 2012 959 964
32. T. Wu, M.J. Bound, S.D. Standfield, M. Bellon, R.L. Young, and K.L. Jones et al. Artificial sweeteners have no effect on gastric emptying, glucagon-like peptide-1, or glycemia after oral glucose in healthy humans Diabetes Care 36 2013 e202 e203
33. R.F. Margolskee, J. Dyer, Z. Kokrashvili, K.S. Salmon, E. Ilegems, and K. Daly et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1 Proc Natl Acad Sci U S A 104 2007 15075 15080
34. O.J. Mace, J. Affleck, N. Patel, and G.L. Kellett Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2 J Physiol 582 2007 379 392
35. J.C. de Ruyter, M.R. Olthof, J.C. Seidell, and M.B. Katan A trial of sugar-free or sugar-sweetened beverages and body weight in children N Engl J Med 367 2012 1397 1406
36. C. Gardner, J. Wylie-Rosett, S.S. Gidding, L.M. Steffen, R.K. Johnson, and D. Reader et al. Nonnutritive sweeteners: current use and health perspectives: a scientific statement from the American Heart Association and the American Diabetes Association Circulation 126 2012 509 519
37. T.I. Jeon, B. Zhu, J.L. Larson, and T.F. Osborne SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice J Clin Invest 118 2008 3693 3700
38. 2+ channels Am J Physiol Cell Physiol 291 2006 C726 C739
39. A.J. Brown, S.M. Goldsworthy, A.A. Barnes, M.M. Eilert, L. Tcheang, and D. Daniels et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids J Biol Chem 278 2003 11312 11319
40. S. Karaki, R. Mitsui, H. Hayashi, I. Kato, H. Sugiya, and T. Iwanaga et al. Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine Cell Tissue Res 324 2006 353 360
41. G. Tolhurst, H. Heffron, Y.S. Lam, H.E. Parker, A.M. Habib, and E. Diakogiannaki et al. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2 Diabetes 61 2012 364 371
42. I. Kaji, S. Karaki, R. Tanaka, and A. Kuwahara Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide J Mol Histol 42 2011 27 38
43. N.M. Delzenne, P.D. Cani, and A.M. Neyrinck Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data J Nutr 137 2007 2547S 2551S
44. A.D. Miras, and C.W. le Roux Mechanisms underlying weight loss after bariatric surgery Nat Rev Gastroenterol Hepatol 10 2013 575 584
45. K.L. Egerod, M.S. Engelstoft, K.V. Grunddal, M.K. Nohr, A. Secher, and I. Sakata et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin Endocrinology 153 2012 5782 5795
46. A.M. Habib, P. Richards, L.S. Cairns, G.J. Rogers, C.A. Bannon, and H.E. Parker et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry Endocrinology 153 2012 3054 3065
47. A.M. Habib, P. Richards, L.S. Cairns, G.J. Rogers, C.A. Bannon, and H.E. Parker et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry Endocrinology 153 2012 3054 3065