-
2
-
-
51649093834
-
Recent advances in head and neck cancer
-
Haddad RI, Shin DM. Recent advances in head and neck cancer. N Engl J Med 2008; 359: 1143-54.
-
(2008)
N Engl J Med
, vol.359
, pp. 1143-1154
-
-
Haddad, R.I.1
Shin, D.M.2
-
3
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-92.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
4
-
-
0037381213
-
Structure and dynamic behavior of nucleosomes
-
Luger K. Structure and dynamic behavior of nucleosomes. Curr Opin Genet Dev 2003; 13: 127-35.
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 127-135
-
-
Luger, K.1
-
5
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD. The language of covalent histone modifications. Nature 2000; 403: 41-5.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
6
-
-
0035325163
-
Histone acetylation and chromatin remodeling
-
Gregory PD, Wagner K, Horz W. Histone acetylation and chromatin remodeling. Exp Cell Res 2001; 265: 195-202.
-
(2001)
Exp Cell Res
, vol.265
, pp. 195-202
-
-
Gregory, P.D.1
Wagner, K.2
Horz, W.3
-
8
-
-
0035862199
-
The human histone deacetylase family
-
Gray SG, Ekstrom TJ. The human histone deacetylase family. Exp Cell Res 2001; 262: 75-83.
-
(2001)
Exp Cell Res
, vol.262
, pp. 75-83
-
-
Gray, S.G.1
Ekstrom, T.J.2
-
9
-
-
0344407016
-
Histone deacetylases: unique players in shaping the epigenetic histone code
-
Thiagalingam S, Cheng KH, Lee HJ, Mineva N, Thiagalingam A, Ponte JF. Histone deacetylases: unique players in shaping the epigenetic histone code. Ann N Y Acad Sci 2003; 983: 84-100.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 84-100
-
-
Thiagalingam, S.1
Cheng, K.H.2
Lee, H.J.3
Mineva, N.4
Thiagalingam, A.5
Ponte, J.F.6
-
11
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G, Guarente L. The Sir2 family of protein deacetylases. Annu Rev Biochem 2004; 73: 417-35.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
12
-
-
28044471827
-
Acetylation and deacetylation of non-histone proteins
-
Glozak MA, Sengupta N, Zhang X, Seto E. Acetylation and deacetylation of non-histone proteins. Gene 2005; 363: 15-23.
-
(2005)
Gene
, vol.363
, pp. 15-23
-
-
Glozak, M.A.1
Sengupta, N.2
Zhang, X.3
Seto, E.4
-
13
-
-
1842578986
-
Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis
-
Gregoretti IV, Lee YM, Goodson HV. Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. J Mol Biol 2004; 338: 17-31.
-
(2004)
J Mol Biol
, vol.338
, pp. 17-31
-
-
Gregoretti, I.V.1
Lee, Y.M.2
Goodson, H.V.3
-
14
-
-
0035755974
-
Histone deacetylases and cancer: causes and therapies
-
Marks P, Rifkind RA, Richon VM, Breslow R, Miller T, Kelly WK. Histone deacetylases and cancer: causes and therapies. Nat Rev Cancer 2001; 1: 194-202.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
Breslow, R.4
Miller, T.5
Kelly, W.K.6
-
15
-
-
0037406061
-
Class II histone deacetylases: versatile regulators
-
Verdin E, Dequiedt F, Kasler HG. Class II histone deacetylases: versatile regulators. Trends Genet 2003; 19: 286-93.
-
(2003)
Trends Genet
, vol.19
, pp. 286-293
-
-
Verdin, E.1
Dequiedt, F.2
Kasler, H.G.3
-
16
-
-
0242330181
-
Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor
-
Bruick RK. Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor. Genes Dev 2003; 17: 2614-23.
-
(2003)
Genes Dev
, vol.17
, pp. 2614-2623
-
-
Bruick, R.K.1
-
17
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
-
Iyer NV, Kotch LE, Agani F, et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 1998; 12: 149-62.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
-
18
-
-
0034006016
-
HIF-1: mediator of physiological and pathophysiological responses to hypoxia
-
Semenza GL. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 2000; 88: 1474-80.
-
(2000)
J Appl Physiol
, vol.88
, pp. 1474-1480
-
-
Semenza, G.L.1
-
19
-
-
0035917313
-
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
-
Ivan M, Kondo K, Yang H, et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001; 292: 464-8.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
-
20
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001; 292: 468-72.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
-
21
-
-
4644370374
-
Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications
-
Brahimi-Horn C, Mazure N, Pouyssegur J. Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications. Cell Signal 2005; 17: 1-9.
-
(2005)
Cell Signal
, vol.17
, pp. 1-9
-
-
Brahimi-Horn, C.1
Mazure, N.2
Pouyssegur, J.3
-
22
-
-
18744375998
-
Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation
-
Jeong JW, Bae MK, Ahn MY, et al. Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell 2002; 111: 709-20.
-
(2002)
Cell
, vol.111
, pp. 709-720
-
-
Jeong, J.W.1
Bae, M.K.2
Ahn, M.Y.3
-
23
-
-
33746776975
-
Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis
-
Chang CC, Lin MT, Lin BR, et al. Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis. J Natl Cancer Inst 2006; 98: 984-95.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 984-995
-
-
Chang, C.C.1
Lin, M.T.2
Lin, B.R.3
-
24
-
-
33744963443
-
Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha
-
Fath DM, Kong X, Liang D, et al. Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha. J Biol Chem 2006; 281: 13612-9.
-
(2006)
J Biol Chem
, vol.281
, pp. 13612-13619
-
-
Fath, D.M.1
Kong, X.2
Liang, D.3
-
25
-
-
33644780111
-
Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha
-
Kong X, Lin Z, Liang D, Fath D, Sang N, Caro J. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha. Mol Cell Biol 2006; 26: 2019-28.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2019-2028
-
-
Kong, X.1
Lin, Z.2
Liang, D.3
Fath, D.4
Sang, N.5
Caro, J.6
-
26
-
-
0035048449
-
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes
-
Kim MS, Kwon HJ, Lee YM, et al. Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med 2001; 7: 437-43.
-
(2001)
Nat Med
, vol.7
, pp. 437-443
-
-
Kim, M.S.1
Kwon, H.J.2
Lee, Y.M.3
-
27
-
-
67349201377
-
Targeting tumor angiogenesis with histone deacetylase inhibitors
-
Ellis L, Hammers H, Pili R. Targeting tumor angiogenesis with histone deacetylase inhibitors. Cancer Lett 2009; 280: 145-53.
-
(2009)
Cancer Lett
, vol.280
, pp. 145-153
-
-
Ellis, L.1
Hammers, H.2
Pili, R.3
-
28
-
-
67449100866
-
Histone deacetylase 2 expression predicts poorer prognosis in oral cancer patients
-
Chang HH, Chiang CP, Hung HC, Lin CY, Deng YT, Kuo MY. Histone deacetylase 2 expression predicts poorer prognosis in oral cancer patients. Oral Oncol 2009; 45: 610-4.
-
(2009)
Oral Oncol
, vol.45
, pp. 610-614
-
-
Chang, H.H.1
Chiang, C.P.2
Hung, H.C.3
Lin, C.Y.4
Deng, Y.T.5
Kuo, M.Y.6
-
29
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga MF, Ballestar E, Villar-Garea A, et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 2005; 37: 391-400.
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
-
30
-
-
73949128107
-
Histone deacetylase inhibitors in cancer therapy
-
Lane AA, Chabner BA. Histone deacetylase inhibitors in cancer therapy. J Clin Oncol 2009; 27: 5459-68.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
|