메뉴 건너뛰기




Volumn 385, Issue 1, 2009, Pages 192-197

Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivation

Author keywords

Autophagy; Cell death; E7 oncoprotein; Human papillomavirus; Keratinocytes; Metabolic stress; Trophic sentinel signaling

Indexed keywords

3 METHYLADENINE; GROWTH FACTOR; PROTEIN E7;

EID: 60649116625     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.12.003     Document Type: Article
Times cited : (51)

References (44)
  • 1
    • 34347238938 scopus 로고    scopus 로고
    • Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways
    • Aoki H., Takada Y., Kondo S., Sawaya R., Aggarwal B.B., and Kondo Y. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol. Pharmacol. 72 1 (2007) 29-39
    • (2007) Mol. Pharmacol. , vol.72 , Issue.1 , pp. 29-39
    • Aoki, H.1    Takada, Y.2    Kondo, S.3    Sawaya, R.4    Aggarwal, B.B.5    Kondo, Y.6
  • 2
    • 40449086885 scopus 로고    scopus 로고
    • Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
    • Apel A., Herr I., Schwarz H., Rodemann H.P., and Mayer A. Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res. 68 5 (2008) 1485-1494
    • (2008) Cancer Res. , vol.68 , Issue.5 , pp. 1485-1494
    • Apel, A.1    Herr, I.2    Schwarz, H.3    Rodemann, H.P.4    Mayer, A.5
  • 3
    • 34548100868 scopus 로고    scopus 로고
    • Modulating autophagy for therapeutic benefit
    • Carew J.S., Nawrocki S.T., and Cleveland J.L. Modulating autophagy for therapeutic benefit. Autophagy 3 5 (2007) 464-467
    • (2007) Autophagy , vol.3 , Issue.5 , pp. 464-467
    • Carew, J.S.1    Nawrocki, S.T.2    Cleveland, J.L.3
  • 4
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
    • Debbas M., and White E. Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev. 7 4 (1993) 546-554
    • (1993) Genes Dev. , vol.7 , Issue.4 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 6
    • 1242315673 scopus 로고    scopus 로고
    • Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation
    • Eichten A., Rud D.S., Grace M., Piboonniyom S.O., Zacny V., and Munger K. Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation. Virology 319 1 (2004) 81-93
    • (2004) Virology , vol.319 , Issue.1 , pp. 81-93
    • Eichten, A.1    Rud, D.S.2    Grace, M.3    Piboonniyom, S.O.4    Zacny, V.5    Munger, K.6
  • 8
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan G.I., and Vousden K.H. Proliferation, cell cycle and apoptosis in cancer. Nature 411 6835 (2001) 342-348
    • (2001) Nature , vol.411 , Issue.6835 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 11
    • 0030827303 scopus 로고    scopus 로고
    • Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein
    • Funk J.O., Waga S., Harry J.B., Espling E., Stillman B., and Galloway D.A. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev. 11 16 (1997) 2090-2100
    • (1997) Genes Dev. , vol.11 , Issue.16 , pp. 2090-2100
    • Funk, J.O.1    Waga, S.2    Harry, J.B.3    Espling, E.4    Stillman, B.5    Galloway, D.A.6
  • 12
    • 33646146195 scopus 로고    scopus 로고
    • Increased in vitro lifespan of primary human keratinocytes correlates with decreased migration
    • Hasskarl J., Velupillai P., and Munger K. Increased in vitro lifespan of primary human keratinocytes correlates with decreased migration. J. Invest. Dermatol. 126 5 (2006) 1179-1181
    • (2006) J. Invest. Dermatol. , vol.126 , Issue.5 , pp. 1179-1181
    • Hasskarl, J.1    Velupillai, P.2    Munger, K.3
  • 13
    • 0030756473 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2
    • Jones D.L., Alani R.M., and Munger K. The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2. Genes Dev. 11 16 (1997) 2101-2111
    • (1997) Genes Dev. , vol.11 , Issue.16 , pp. 2101-2111
    • Jones, D.L.1    Alani, R.M.2    Munger, K.3
  • 14
    • 0031438309 scopus 로고    scopus 로고
    • Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis
    • Jones D.L., Thompson D.A., and Munger K. Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis. Virology 239 1 (1997) 97-107
    • (1997) Virology , vol.239 , Issue.1 , pp. 97-107
    • Jones, D.L.1    Thompson, D.A.2    Munger, K.3
  • 15
    • 0033526505 scopus 로고    scopus 로고
    • Expression of the HPV E7 oncoprotein mimics but does not evoke a p53-dependent cellular DNA damage response pathway
    • Jones D.L., Thompson D.A., Suh-Burgmann E., Grace M., and Munger K. Expression of the HPV E7 oncoprotein mimics but does not evoke a p53-dependent cellular DNA damage response pathway. Virology 258 2 (1999) 406-414
    • (1999) Virology , vol.258 , Issue.2 , pp. 406-414
    • Jones, D.L.1    Thompson, D.A.2    Suh-Burgmann, E.3    Grace, M.4    Munger, K.5
  • 16
    • 0033982820 scopus 로고    scopus 로고
    • Studies on the breakdown of glycogen in the lysosomes: the effects of hydrocortisone
    • Kalamidas S.A., and Kotoulas O.B. Studies on the breakdown of glycogen in the lysosomes: the effects of hydrocortisone. Histol. Histopathol. 15 1 (2000) 29-35
    • (2000) Histol. Histopathol. , vol.15 , Issue.1 , pp. 29-35
    • Kalamidas, S.A.1    Kotoulas, O.B.2
  • 17
    • 35848947032 scopus 로고    scopus 로고
    • Role of autophagy in breast cancer
    • Karantza-Wadsworth V., and White E. Role of autophagy in breast cancer. Autophagy 3 6 (2007) 610-613
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 610-613
    • Karantza-Wadsworth, V.1    White, E.2
  • 18
    • 48249090416 scopus 로고    scopus 로고
    • Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer
    • Kim K.W., Hwang M., Moretti L., Jaboin J.J., Cha Y.I., and Lu B. Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy 4 5 (2008) 659-668
    • (2008) Autophagy , vol.4 , Issue.5 , pp. 659-668
    • Kim, K.W.1    Hwang, M.2    Moretti, L.3    Jaboin, J.J.4    Cha, Y.I.5    Lu, B.6
  • 19
    • 34248583762 scopus 로고    scopus 로고
    • Methods for monitoring autophagy from yeast to human
    • Klionsky D.J., Cuervo A.M., and Seglen P.O. Methods for monitoring autophagy from yeast to human. Autophagy 3 3 (2007) 181-206
    • (2007) Autophagy , vol.3 , Issue.3 , pp. 181-206
    • Klionsky, D.J.1    Cuervo, A.M.2    Seglen, P.O.3
  • 21
    • 4344712684 scopus 로고    scopus 로고
    • Methods for monitoring autophagy
    • Mizushima N. Methods for monitoring autophagy. Int. J. Biochem. Cell Biol. 36 12 (2004) 2491-2502
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , Issue.12 , pp. 2491-2502
    • Mizushima, N.1
  • 22
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N., and Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 3 6 (2007) 542-545
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 23
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N., Levine B., Cuervo A.M., and Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 451 7182 (2008) 1069-1075
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 24
    • 0024428508 scopus 로고
    • The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
    • Munger K., Phelps W.C., Bubb V., Howley P.M., and Schlegel R. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J. Virol. 63 10 (1989) 4417-4421
    • (1989) J. Virol. , vol.63 , Issue.10 , pp. 4417-4421
    • Munger, K.1    Phelps, W.C.2    Bubb, V.3    Howley, P.M.4    Schlegel, R.5
  • 25
    • 0035956258 scopus 로고    scopus 로고
    • Biological activities and molecular targets of the human papillomavirus E7 oncoprotein
    • Munger K., Basile J.R., Duensing S., Eichten A., Gonzalez S.L., Grace M., and Zacny V.L. Biological activities and molecular targets of the human papillomavirus E7 oncoprotein. Oncogene 20 54 (2001) 7888-7898
    • (2001) Oncogene , vol.20 , Issue.54 , pp. 7888-7898
    • Munger, K.1    Basile, J.R.2    Duensing, S.3    Eichten, A.4    Gonzalez, S.L.5    Grace, M.6    Zacny, V.L.7
  • 26
    • 0037013147 scopus 로고    scopus 로고
    • Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
    • Pelengaris S., Khan M., and Evan G.I. Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell 109 3 (2002) 321-334
    • (2002) Cell , vol.109 , Issue.3 , pp. 321-334
    • Pelengaris, S.1    Khan, M.2    Evan, G.I.3
  • 27
    • 0037439799 scopus 로고    scopus 로고
    • Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability
    • Piboonniyom S.O., Duensing S., Swilling N.W., Hasskarl J., Hinds P.W., and Munger K. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. Cancer Res. 63 2 (2003) 476-483
    • (2003) Cancer Res. , vol.63 , Issue.2 , pp. 476-483
    • Piboonniyom, S.O.1    Duensing, S.2    Swilling, N.W.3    Hasskarl, J.4    Hinds, P.W.5    Munger, K.6
  • 28
    • 0023152810 scopus 로고
    • Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA
    • Pirisi L., Yasumoto S., Feller M., Doniger J., and DiPaolo J.A. Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA. J. Virol. 61 4 (1987) 1061-1066
    • (1987) J. Virol. , vol.61 , Issue.4 , pp. 1061-1066
    • Pirisi, L.1    Yasumoto, S.2    Feller, M.3    Doniger, J.4    DiPaolo, J.A.5
  • 29
    • 49649121765 scopus 로고    scopus 로고
    • E2F1 regulates autophagy and the transcription of autophagy genes
    • Polager S., Ofir M., and Ginsberg D. E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 27 35 (2008) 4860-4864
    • (2008) Oncogene , vol.27 , Issue.35 , pp. 4860-4864
    • Polager, S.1    Ofir, M.2    Ginsberg, D.3
  • 30
    • 0342546018 scopus 로고    scopus 로고
    • E1A is sufficient by itself to induce apoptosis independent of p53 and other adenoviral gene products
    • Putzer B.M., Stiewe T., Parssanedjad K., Rega S., and Esche H. E1A is sufficient by itself to induce apoptosis independent of p53 and other adenoviral gene products. Cell Death Differ. 7 2 (2000) 177-188
    • (2000) Cell Death Differ. , vol.7 , Issue.2 , pp. 177-188
    • Putzer, B.M.1    Stiewe, T.2    Parssanedjad, K.3    Rega, S.4    Esche, H.5
  • 31
    • 0026639932 scopus 로고
    • The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins
    • Rao L., Debbas M., Sabbatini P., Hockenbery D., Korsmeyer S., and White E. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. Proc. Natl. Acad. Sci. U. S. A. 89 16 (1992) 7742-7746
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , Issue.16 , pp. 7742-7746
    • Rao, L.1    Debbas, M.2    Sabbatini, P.3    Hockenbery, D.4    Korsmeyer, S.5    White, E.6
  • 32
    • 0018902467 scopus 로고
    • Serial cultivation of normal human epidermal keratinocytes
    • Rheinwald J.G. Serial cultivation of normal human epidermal keratinocytes. Methods Cell Biol. 21A (1980) 229-254
    • (1980) Methods Cell Biol. , vol.21 A , pp. 229-254
    • Rheinwald, J.G.1
  • 33
    • 0019124443 scopus 로고
    • Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes
    • Rheinwald J.G., and Beckett M.A. Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell 22 2 Pt 2 (1980) 629-632
    • (1980) Cell , vol.22 , Issue.2 PART 2 , pp. 629-632
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 34
    • 35448980704 scopus 로고    scopus 로고
    • Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
    • Sato K., Tsuchihara K., Fujii S., Sugiyama M., Goya T., Atomi Y., Ueno T., Ochiai A., and Esumi H. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res. 67 20 (2007) 9677-9684
    • (2007) Cancer Res. , vol.67 , Issue.20 , pp. 9677-9684
    • Sato, K.1    Tsuchihara, K.2    Fujii, S.3    Sugiyama, M.4    Goya, T.5    Atomi, Y.6    Ueno, T.7    Ochiai, A.8    Esumi, H.9
  • 35
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M., Werness B.A., Huibregtse J.M., Levine A.J., and Howley P.M. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63 6 (1990) 1129-1136
    • (1990) Cell , vol.63 , Issue.6 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 36
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner M., Huibregtse J.M., Vierstra R.D., and Howley P.M. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75 3 (1993) 495-505
    • (1993) Cell , vol.75 , Issue.3 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 38
    • 0005677775 scopus 로고
    • 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • Seglen P.O., and Gordon P.B. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Natl. Acad. Sci. U. S. A. 79 6 (1982) 1889-1892
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , Issue.6 , pp. 1889-1892
    • Seglen, P.O.1    Gordon, P.B.2
  • 40
    • 0029147167 scopus 로고
    • Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms
    • Teodoro J.G., Shore G.C., and Branton P.E. Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms. Oncogene 11 3 (1995) 467-474
    • (1995) Oncogene , vol.11 , Issue.3 , pp. 467-474
    • Teodoro, J.G.1    Shore, G.C.2    Branton, P.E.3
  • 41
    • 0026049728 scopus 로고
    • Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins
    • White E., Cipriani R., Sabbatini P., and Denton A. Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins. J. Virol. 65 6 (1991) 2968-2978
    • (1991) J. Virol. , vol.65 , Issue.6 , pp. 2968-2978
    • White, E.1    Cipriani, R.2    Sabbatini, P.3    Denton, A.4
  • 43
    • 0030443870 scopus 로고    scopus 로고
    • Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein
    • Zerfass-Thome K., Zwerschke W., Mannhardt B., Tindle R., Botz J.W., and Jansen-Durr P. Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein. Oncogene 13 11 (1996) 2323-2330
    • (1996) Oncogene , vol.13 , Issue.11 , pp. 2323-2330
    • Zerfass-Thome, K.1    Zwerschke, W.2    Mannhardt, B.3    Tindle, R.4    Botz, J.W.5    Jansen-Durr, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.