Tethered protein display identifies a novel kir3.2 (GIRK2) regulator from protein scaffold libraries

ACS Chemical Neuroscience

Volumn 5, Issue 9, 2014, Pages 812-822

  Bagriantsev, Sviatoslav N ^a,e   Chatelain, Franck C ^a,f   Clark, Kimberly A ^a   Alagem, Noga ^d   Reuveny, Eitan ^d   Minor, Daniel L ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Channel activation; GIRK; Randomized libraries; Tethered protein display; Trafficking, inward rectifier

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3.2; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; KCNJ6 PROTEIN, MOUSE; PEPTIDE LIBRARY; PROTEIN SUBUNIT;

ARTICLE; CELL DENSITY; CELL SURFACE; CONTROLLED STUDY; FUNGAL STRAIN; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; ANIMAL; CHANNEL GATING; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROINJECTION; MOUSE; OOCYTE; PATCH CLAMP TECHNIQUE; PROTEIN SUBUNIT; PROTEIN TRANSPORT; XENOPUS LAEVIS;

MAMMALIA;

ANIMALS; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENE EXPRESSION REGULATION; ION CHANNEL GATING; MICE; MICROINJECTIONS; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDE LIBRARY; PROTEIN SUBUNITS; PROTEIN TRANSPORT; XENOPUS LAEVIS;

EID: 84924980553     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn5000698     Document Type: Article

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