The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors

Human Molecular Genetics

Volumn 24, Issue 1, 2015, Pages 128-141

  Luhmann, Ulrich F O ^a   Carvalho, Livia S ^a   Holthaus, Sophia Martha kleine ^a,b   Cowing, Jill A ^a   Greenaway, Simon ^a   Chu, Colin J ^a   Herrmann, Philipp ^a   Smith, Alexander J ^a   Munro, Peter M G ^a   Potter, Paul ^c   Bainbridge, James W B ^a,d   Ali, Robin R ^a,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

^d MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CX3CR1; CRUMBS HOMOLOGUE 1 PROTEIN; FRACTALKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; MEMBRANE PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN ZO1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CRB1 PROTEIN, MOUSE; NERVE PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACKCROSSING; CELL ACTIVATION; CELL ADHESION; CHROMOSOME 15; CONTROLLED STUDY; CRUMBS HOMOLOGUE 1 GENE; DISEASE SEVERITY; EYE FUNDUS; GENE; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; MICROGLIA; MOUSE; MUELLER CELL; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RETINA DEGENERATION; RETINAL TELANGIECTASIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING LASER OPHTHALMOSCOPY; SINGLE NUCLEOTIDE POLYMORPHISM; VASCULAR LESION; VASCULAR REMODELING; WILD TYPE; ANIMAL; CHROMOSOME; FLUORESCENCE ANGIOGRAPHY; GENETIC ASSOCIATION STUDY; GENETICS; HUMAN; INBRED MOUSE STRAIN; METABOLISM; MUTATION; OPHTHALMOSCOPE; PATHOLOGY; PHOTORECEPTOR CELL; RETINA; RETINA BLOOD VESSEL; RETINA DISEASE;

MUS;

ANIMALS; CHROMOSOMES, MAMMALIAN; FLUORESCEIN ANGIOGRAPHY; GENETIC ASSOCIATION STUDIES; HUMANS; MICE; MICE, INBRED STRAINS; MUTATION; NERVE TISSUE PROTEINS; OPHTHALMOSCOPES; PHOTORECEPTOR CELLS, VERTEBRATE; POLYMORPHISM, SINGLE NUCLEOTIDE; RETINA; RETINAL DISEASES; RETINAL VESSELS;

EID: 84922545670     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu424     Document Type: Article

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