Lipid-bloated subretinal microglial cells are at the origin of drusen appearance in CX3CR1-deficient mice

Ophthalmic Research

Volumn 40, Issue 3-4, 2008, Pages 115-119

  Raoul, W ^a,b,c   Feumi, C ^a,b,c   Keller, N ^a,b,c   Lavalette, S ^a,b,c   Houssier, M ^a,b,c   Behar Cohen, F ^a,b,c,e   Combadiere C ^a,c,d,e   Sennlaub, F ^a,b,c  

^a INSERM   (France)

^b CENTRE DE RECHERCHE DES CORDELIERS   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e HÔTEL DIEU   (France)

Author keywords

CX3CR1 deficient mice; Drusen appearance; Lipid bloated subretinal microglial cells

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; LIPID;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUSEN; KNOCKOUT MOUSE; LIPID METABOLISM; MICROGLIA; MOUSE; NONHUMAN; OPHTHALMOSCOPY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RETINA GANGLION CELL; RETINA MACULA AGE RELATED DEGENERATION;

ANIMALS; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; PIGMENT EPITHELIUM OF EYE; RECEPTORS, CHEMOKINE; RETINAL DRUSEN; SEVERITY OF ILLNESS INDEX;

EID: 42449093343     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000119860     Document Type: Article

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