-
1
-
-
84890502599
-
Incorporating novel agents in the management of elderly myeloma patients
-
Guglielmelli T and Palumbo A: Incorporating novel agents in the management of elderly myeloma patients. Curr Hematol Malig Rep 8: 261-269, 2013.
-
(2013)
Curr Hematol Malig Rep
, vol.8
, pp. 261-269
-
-
Guglielmelli, T.1
Palumbo, A.2
-
2
-
-
84877111787
-
Management of older adults with multiple myeloma
-
Palumbo A and Mina R: Management of older adults with multiple myeloma. Blood Rev 27: 133-142, 2013.
-
(2013)
Blood Rev
, vol.27
, pp. 133-142
-
-
Palumbo, A.1
Mina, R.2
-
3
-
-
84866433650
-
Pre-existing diabetes mellitus in patients with multiple myeloma
-
Chou YS, Yang CF, Chen HS, et al: Pre-existing diabetes mellitus in patients with multiple myeloma. Eur J Haematol 89: 320-327, 2012.
-
(2012)
Eur J Haematol
, vol.89
, pp. 320-327
-
-
Chou, Y.S.1
Yang, C.F.2
Chen, H.S.3
-
5
-
-
84900027881
-
The impact of hyperglycemia on risk of severe infections during early period of induction therapy in patients with newly diagnosed multiple myeloma
-
Jung SH, Jang HC, Lee SS, et al: The impact of hyperglycemia on risk of severe infections during early period of induction therapy in patients with newly diagnosed multiple myeloma. Biomed Res Int 2014: 413149, 2014.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 413149
-
-
Jung, S.H.1
Jang, H.C.2
Lee, S.S.3
-
6
-
-
84877622855
-
Clinical challenges: Myeloma and concomitant type 2 diabetes
-
Ahmed YA and Eltayeb A: Clinical challenges: myeloma and concomitant type 2 diabetes. Int J Hematol Oncol Stem Cell Res 7: 34-41, 2013.
-
(2013)
Int J Hematol Oncol Stem Cell Res
, vol.7
, pp. 34-41
-
-
Ahmed, Y.A.1
Eltayeb, A.2
-
7
-
-
84905226036
-
The association of diabetes and anti-diabetic medications with clinical outcomes in multiple myeloma
-
Wu W, Merriman K, Nabaah A, et al: The association of diabetes and anti-diabetic medications with clinical outcomes in multiple myeloma. Br J Cancer 111: 628-636, 2014.
-
(2014)
Br J Cancer
, vol.111
, pp. 628-636
-
-
Wu, W.1
Merriman, K.2
Nabaah, A.3
-
8
-
-
33845974431
-
Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer
-
Chiu BC, Gapstur SM, Greenland P, Wang R and Dyer A: Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer. Cancer Epidemiol Biomarkers Prev 15: 2348-2354, 2006.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 2348-2354
-
-
Chiu, B.C.1
Gapstur, S.M.2
Greenland, P.3
Wang, R.4
Dyer, A.5
-
9
-
-
0025732948
-
Role of oxidative stress in development of complications in diabetes
-
Baynes JW: Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-412, 1991.
-
(1991)
Diabetes
, vol.40
, pp. 405-412
-
-
Baynes, J.W.1
-
10
-
-
48249091745
-
Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators
-
Busik JV, Mohr S and Grant MB: Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators. Diabetes 57: 1952-1965, 2008.
-
(2008)
Diabetes
, vol.57
, pp. 1952-1965
-
-
Busik, J.V.1
Mohr, S.2
Grant, M.B.3
-
11
-
-
84903649897
-
Mitochondrial reactive oxygen species (ros) and ros-induced ros release
-
Zorov DB, Juhaszova M and Sollott SJ: Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol Rev 94: 909-950, 2014.
-
(2014)
Physiol Rev
, vol.94
, pp. 909-950
-
-
Zorov, D.B.1
Juhaszova, M.2
Sollott, S.J.3
-
12
-
-
84856220825
-
Strategies to target mitochondria and oxidative stress by antioxidants: Key points and perspectives
-
Edeas M: Strategies to target mitochondria and oxidative stress by antioxidants: key points and perspectives. Pharm Res 28: 2771-2779, 2011.
-
(2011)
Pharm Res
, vol.28
, pp. 2771-2779
-
-
Edeas, M.1
-
13
-
-
84655169936
-
Tumor suppressor genes and ros: Complex networks of interactions
-
Vurusaner B, Poli G and Basaga H: Tumor suppressor genes and ROS: complex networks of interactions. Free Radic Biol Med 52: 7-18, 2012.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 7-18
-
-
Vurusaner, B.1
Poli, G.2
Basaga, H.3
-
14
-
-
19444365211
-
Pgc-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells
-
Valle I, Alvarez-Barrientos A, Arza E, Lamas S and Monsalve M: PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc Res 66: 562-573, 2005.
-
(2005)
Cardiovasc Res
, vol.66
, pp. 562-573
-
-
Valle, I.1
Alvarez-Barrientos, A.2
Arza, E.3
Lamas, S.4
Monsalve, M.5
-
15
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa T, Edelstein D, Du XL, et al: Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404: 787-790, 2000.
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
-
16
-
-
33644660537
-
Pgc-1 coactivators: Inducible regulators of energy metabolism in health and disease
-
Finck BN and Kelly DP: PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 116: 615-622, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
17
-
-
84896701810
-
Pgc-1? Integrates glucose metabolism and angiogenesis in multiple myeloma cells by regulating vegf and glut-4
-
Cao D, Zhou H, Zhao J, et al: PGC-1? integrates glucose metabolism and angiogenesis in multiple myeloma cells by regulating VEGF and GLUT-4. Oncol Rep 31: 1205-1210, 2014.
-
(2014)
Oncol Rep
, vol.31
, pp. 1205-1210
-
-
Cao, D.1
Zhou, H.2
Zhao, J.3
-
18
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the pgc-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, et al: Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127: 397-408, 2006.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
-
19
-
-
77955347446
-
Sirtuin 3, a new target of pgc-1 alpha, plays an important role in the suppression of ros and mitochondrial biogenesis
-
Kong X, Wang R, Xue Y, et al: Sirtuin 3, a new target of PGC-1 alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One 5: e11707, 2010.
-
(2010)
PLoS One
, vol.5
, pp. e11707
-
-
Kong, X.1
Wang, R.2
Xue, Y.3
-
20
-
-
58149473706
-
Tzds reduce mitochondrial ros production and enhance mitochondrial biogenesis
-
Fujisawa K, Nishikawa T, Kukidome D, et al: TZDs reduce mitochondrial ROS production and enhance mitochondrial biogenesis. Biochem Biophys Res Commun 379: 43-48, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 43-48
-
-
Fujisawa, K.1
Nishikawa, T.2
Kukidome, D.3
-
21
-
-
84875454999
-
Novel small-molecule pgc-1? Transcriptional regulator with beneficial effects on diabetic db/db mice
-
Zhang LN, Zhou HY, Fu YY, et al: Novel small-molecule PGC-1? transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes 62: 1297-1307, 2013.
-
(2013)
Diabetes
, vol.62
, pp. 1297-1307
-
-
Zhang, L.N.1
Zhou, H.Y.2
Fu, Y.Y.3
-
22
-
-
67650096912
-
Enhancing cd8 t-cell memory by modulating fatty acid metabolism
-
Pearce EL, Walsh MC, Cejas PJ, et al: Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 460: 103-107, 2009.
-
(2009)
Nature
, vol.460
, pp. 103-107
-
-
Pearce, E.L.1
Walsh, M.C.2
Cejas, P.J.3
-
23
-
-
84864987812
-
Impact of diabetes and hyperglycemia on survival in advanced breast cancer patients
-
Villarreal-Garza C, Shaw-Dulin R, Lara-Medina F, et al: Impact of diabetes and hyperglycemia on survival in advanced breast cancer patients. Exp Diabetes Res 2012: 732027, 2012.
-
(2012)
Exp Diabetes Res
, vol.2012
, pp. 732027
-
-
Villarreal-Garza, C.1
Shaw-Dulin, R.2
Lara-Medina, F.3
-
24
-
-
84859432857
-
Fasting blood glucose level and prognosis in non-small cell lung cancer (nsclc) patients
-
Luo J, Chen YJ and Chang LJ: Fasting blood glucose level and prognosis in non-small cell lung cancer (NSCLC) patients. Lung Cancer 76: 242-247, 2012.
-
(2012)
Lung Cancer
, vol.76
, pp. 242-247
-
-
Luo, J.1
Chen, Y.J.2
Chang, L.J.3
-
25
-
-
80052689577
-
Response to dexamethasone is glucose-sensitive in multiple myeloma cell lines
-
Friday E, Ledet J and Turturro F: Response to dexamethasone is glucose-sensitive in multiple myeloma cell lines. J Exp Clin Cancer Res 30: 81, 2011.
-
(2011)
J Exp Clin Cancer Res
, vol.30
, pp. 81
-
-
Friday, E.1
Ledet, J.2
Turturro, F.3
-
27
-
-
84881370628
-
Incident hyperglycemia, parenteral nutrition administration and adverse outcomes in patients with myeloma admitted for initial auto-sct
-
Sheean PM, Kilkus JM, Liu D, Maciejewski J and Braunschweig CA: Incident hyperglycemia, parenteral nutrition administration and adverse outcomes in patients with myeloma admitted for initial auto-SCT. Bone Marrow Transplant 48: 1117-1122, 2013.
-
(2013)
Bone Marrow Transplant
, vol.48
, pp. 1117-1122
-
-
Sheean, P.M.1
Kilkus, J.M.2
Liu, D.3
Maciejewski, J.4
Braunschweig, C.A.5
-
28
-
-
84861215287
-
Multiple myeloma exhibits novel dependence on glut4 glut8, and glut11: Implications for glucose transporter-directed therapy
-
McBrayer SK, Cheng JC, Singhal S, Krett NL, Rosen ST and Shanmugam M: Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy. Blood 119: 4686-4697, 2012.
-
(2012)
Blood
, vol.119
, pp. 4686-4697
-
-
McBrayer, S.K.1
Cheng, J.C.2
Singhal, S.3
Krett, N.L.4
Rosen, S.T.5
Shanmugam, M.6
-
29
-
-
84875890762
-
Targeting cellular metabolism to improve cancer therapeutics
-
Zhao Y, Butler EB and Tan M: Targeting cellular metabolism to improve cancer therapeutics. Cell Death Dis 4: e532, 2013.
-
(2013)
Cell Death Dis
, vol.4
, pp. e532
-
-
Zhao, Y.1
Butler, E.B.2
Tan, M.3
-
30
-
-
84896797170
-
Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
-
Gitenay D, Wiel C, Lallet-Daher H, et al: Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence. Cell Death Dis 5: e1089, 2014.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1089
-
-
Gitenay, D.1
Wiel, C.2
Lallet-Daher, H.3
-
31
-
-
79955023800
-
Emerging metabolic targets in cancer therapy
-
Zhao Y, Liu H, Riker AI, et al: Emerging metabolic targets in cancer therapy. Front Biosci (Landmark Ed) 16: 1844-1860, 2011.
-
(2011)
Front Biosci (Landmark Ed
, vol.16
, pp. 1844-1860
-
-
Zhao, Y.1
Liu, H.2
Riker, A.I.3
-
32
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis RJ, Mancuso A, Daikhin E, et al: Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci USA 104: 19345-19350, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
-
33
-
-
34250179471
-
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize mcl-1
-
Zhao Y, Altman BJ, Coloff JL, et al: Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol 27: 4328-4339, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4328-4339
-
-
Zhao, Y.1
Altman, B.J.2
Coloff, J.L.3
-
34
-
-
0041357164
-
Bad and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
-
Danial NN, Gramm CF, Scorrano L, et al: BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 424: 952-956, 2003.
-
(2003)
Nature
, vol.424
, pp. 952-956
-
-
Danial, N.N.1
Gramm, C.F.2
Scorrano, L.3
-
35
-
-
0141863388
-
Akt-directed glucose metabolism can prevent bax conformation change and promote growth factor?independent survival
-
Rathmell JC, Fox CJ, Plas DR, Hammerman PS, Cinalli RM and Thompson CB: Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor?independent survival. Mol Cell Biol 23: 7315-7328, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7315-7328
-
-
Rathmell, J.C.1
Fox, C.J.2
Plas, D.R.3
Hammerman, P.S.4
Cinalli, R.M.5
Thompson, C.B.6
-
36
-
-
33746924468
-
Hexokinase ii: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
-
Mathupala SP, Ko YH and Pedersen PL: Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. Oncogene 25: 4777-4786, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 4777-4786
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
37
-
-
0035863104
-
Oxidation of pyridine nucleotides during fas-and ceramide-induced apoptosis in jurkat cells: Correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation
-
Gendron MC, Schrantz N, Metivier D, et al: Oxidation of pyridine nucleotides during Fas-and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation. Biochem J 353: 357-367, 2001.
-
(2001)
Biochem J
, vol.353
, pp. 357-367
-
-
Gendron, M.C.1
Schrantz, N.2
Metivier, D.3
-
38
-
-
84867424051
-
A randomized controlled trial of an intensive insulin regimen in patients with hyperglycemic acute lymphoblastic leukemia
-
Vu K, Busaidy N, Cabanillas ME, et al: A randomized controlled trial of an intensive insulin regimen in patients with hyperglycemic acute lymphoblastic leukemia. Clin Lymphoma Myeloma Leuk 12: 355-362, 2012.
-
(2012)
Clin Lymphoma Myeloma Leuk
, vol.12
, pp. 355-362
-
-
Vu, K.1
Busaidy, N.2
Cabanillas, M.E.3
-
39
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M and Spiegelman BM: A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92: 829-839, 1998.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
40
-
-
84867375467
-
Role of pgc-1? Signaling in skeletal muscle health and disease
-
Kang C and Li Ji L: Role of PGC-1? signaling in skeletal muscle health and disease. Ann NY Acad Sci 1271: 110-117, 2012.
-
(2012)
Ann NY Acad Sci
, vol.1271
, pp. 110-117
-
-
Kang, C.1
Li Ji, L.2
-
41
-
-
84873459937
-
Oxygen consumption and usage during physical exercise: The balance between oxidative stress and ros-dependent adaptive signaling
-
Radak Z, Zhao Z, Koltai E, Ohno H and Atalay M: Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling. Antioxid Redox Signal 18: 1208-1246, 2013.
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1208-1246
-
-
Radak, Z.1
Zhao, Z.2
Koltai, E.3
Ohno, H.4
Atalay, M.5
-
42
-
-
84875246546
-
Regulation of mitochondrial biogenesis and pgc-1? under cellular stress
-
Wenz T: Regulation of mitochondrial biogenesis and PGC-1? under cellular stress. Mitochondrion 13: 134-142, 2013.
-
(2013)
Mitochondrion
, vol.13
, pp. 134-142
-
-
Wenz, T.1
-
43
-
-
84869438139
-
Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance
-
Salem AF, Whitaker-Menezes D, Howell A, Sotgia F and Lisanti MP: Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance. Cell Cycle 11: 4174-4180, 2012.
-
(2012)
Cell Cycle
, vol.11
, pp. 4174-4180
-
-
Salem, A.F.1
Whitaker-Menezes, D.2
Howell, A.3
Sotgia, F.4
Lisanti, M.P.5
-
44
-
-
85027952132
-
Androgens regulate prostate cancer cell growth via an ampk-pgc-1?-mediated metabolic switch
-
Tennakoon JB, Shi Y, Han JJ, et al: Androgens regulate prostate cancer cell growth via an AMPK-PGC-1?-mediated metabolic switch. Oncogene 33: 5251-5261, 2014.
-
(2014)
Oncogene
, vol.33
, pp. 5251-5261
-
-
Tennakoon, J.B.1
Shi, Y.2
Han, J.J.3
-
45
-
-
84861980898
-
The diverse role of the ppar? Coactivator 1 family of transcriptional coactivators in cancer
-
Girnun GD: The diverse role of the PPAR? coactivator 1 family of transcriptional coactivators in cancer. Semin Cell Dev Biol 23: 381-388, 2012.
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 381-388
-
-
Girnun, G.D.1
|