Strategies to target mitochondria and oxidative stress by antioxidants: Key points and perspectives

Pharmaceutical Research

Volumn 28, Issue 11, 2011, Pages 2771-2779

  Edeas, Marvin ^a  

^a Institute for Antioxidants Applications   (France)

Author keywords

Antioxidant; Mitochondria; Oxidative stress; Standardization methods

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CAROTENOID; CATALASE; EPIGALLOCATECHIN GALLATE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; POLYPHENOL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE DISMUTASE; UBIQUINONE; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE;

AEROBIC METABOLISM; ANTIOXIDANT ACTIVITY; BIOACCUMULATION; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; DRUG MECHANISM; DRUG TARGETING; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; GLYCATION; HUMAN; INTRACELLULAR SIGNALING; LIPID PEROXIDATION; MALE INFERTILITY; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TARGETING SIGNAL; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

ANTIOXIDANTS; CLINICAL TRIALS AS TOPIC; HUMANS; MALE; MITOCHONDRIA; MOLECULAR TARGETED THERAPY; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84856220825     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0587-2     Document Type: Review

References (53)

1. Halliwell B. Oxygen radicals: a commonsense look at their nature and medical importance. Med Biol. 1984;62(2):71-77. (Pubitemid 14095822)
2. Halliwell B. The wanderings of free radicals. Free Radic Biol Med. 2009;46:531-542.
3. McCord JM, Edeas MA. SOD, oxidative stress and human pathologies: a brief history and a future vision. Biomed Pharmacother. 2005;59(4):139-42. (Pubitemid 40603324)
4. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol. 2007;39(1):44-84. (Pubitemid 44566469)
5. Cadenas E, Davies KJ. Mitochondrial free radical generation, oxidative stress, and aging. Free Rad Biol Med. 2000;29(3-4):222-230.
6. Piotrowski WJ, Marczak J. Cellular sources of oxidants in the lung. Int J Occup Med Environ Health. 2000;13(4):369-385. (Pubitemid 32125038)
7. Rammal H, Bouayed J, Soulimani R. A direct relationship between aggressive behavior in the resident/intruder test and cell oxidative status in adult male mice. Eur J Pharmacol. 2010;627(1-3):173-176.
8. Van Heerebeek L, Meischl C, Stooker W, Meijer CJ, Niessen HW, Roos D. NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system? J Clin Pathol. 2002;55 (8):561-568.
9. Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res. 2000;86 (5):494-501. (Pubitemid 30165039)
10. Omura T. Forty years of cytochrome P450. Biochem Biophys Res Commun. 1999;266(3):690-698. (Pubitemid 30042494)
11. Klebanoff SJ. Myeloperoxidase: friend and foe. J Leukoc Biol. 2005;77(5):598-625. (Pubitemid 40628741)
12. Gizi A, Papassotiriou I, Apostolakou F, et al. Assessment of oxidative stress in patients with sickle cell disease: The glutathione system and the oxidant-antioxidant status. Blood Cells Mol Dis. 2007;46(3):220-225.
13. Trinei M, Giorgio M, Cicalese A, Barozzi S, Ventura A, Migliaccio E, et al. A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene. 2002;21(24):3872-78. (Pubitemid 34620855)
14. Edeas M. Antioxidants, Controversies and Perspectives: How to explain the failure of clinical studies using antioxidants? J Soc Biol. 2009;203(3):271-80.
15. Grune T. Oxidants and antioxidative defense. Hum Exp Toxicol. 2002;21(2):61-62. (Pubitemid 34591264)
16. Misciagna G, De Michele G, Trevisan M. Non enzymatic glycated proteins in the blood and cardiovascular disease. Curr Pharm Des. 2007;13(36):3688-95.
17. Ravelojaona V, Péterszegi G, Molinari J, Gesztesi JL, Robert L. Demonstration of the cytotoxic effect of Advanced Glycation Endproducts (AGE-s). J Soc Biol. 2007;201(2):185-8. (Pubitemid 350033590)
18. Wang AL, Yu A, Qi H, Zhu XA, Tso M. AGEs mediated expression and secretion of TNF alpha in rat retinal microglia. Exp Eye Res. 2007;84(5):905-913. (Pubitemid 46613882)
19. Martin KR, Barrett JC. Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity. Hum Exp Toxicol. 2002;21(2):71-75. (Pubitemid 34591267)
20. Sarmadi BH, Ismail A. Antioxidative peptides from food proteins: a review. Peptides. 2010;31(10):1949-1956.
21. Sagun KC, Carcamo JM, Golde DW. Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury. FASEB J. 2005;19(12):1657-67. (Pubitemid 41429523)
22. Frankel EN, Finley JW. How to standardize the multiplicity of methods to evaluate natural antioxidants. J Agric Food Chem. 2008;56:4901-4908. (Pubitemid 352039082)
23. Yin H. New techniques to detect oxidative stress markers: mass spectrometry-based methods to detect isoprostanes as the gold standard for oxidative stress in vivo. BioFactors (Oxford, England). 2008;34(2):109-124.
24. Sies H. Total antioxidant capacity: Appraisal of a concept. J Nutr. 2007;137:1493-1495. (Pubitemid 46855492)
25. Bouayed J, Bohn T. Exogenous antioxidants-Double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses. Oxid Med Cell Longev. 2010;3(4):228-237.
26. Patel SR, Sigman M. Antioxidant therapy in male infertility. Urol Clin N Am. 2008;35(2):319-330. (Pubitemid 351514779)
27. Tremellen K. Oxidative stress and male infertility-A clinical perspective. Hum Reprod Update. 2008;14(3):243-258. (Pubitemid 351566975)
28. Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta. 2006;1757(5-6):509-517.
29. Gutierrez J, Ballinger SW, Darley-Usmar VM, Landar A. Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells. Circ Res. 2006;99(9):924-932. (Pubitemid 44657795)
30. Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes. 2005;54(6):1615-25. (Pubitemid 40770750)
31. Yu T, Robotham JL, Yoon Y. Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc Natl Acad Sci USA. 2006;103(8):2653-8.
32. Green K, Brand MD, Murphy MP. Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes. 2004;53 Suppl 1:110-8.
33. Edeas M, Attaf D, Mailfert AS, Nasu M, Joubet R. Maillard reaction, mitochondria and oxidative stress: potential role of antioxidants. Pathol Biol. 2010;58(3):220-225.
34. Mustata GT, Rosca M, Biemel KM, Reihl O, Smith MA, Viswanathan A, et al. Paradoxical effects of green tea (Camellia sinensis) and antioxidant vitamins in diabetic rats: improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking. Diabetes. 2005;54 (2):517-26.
35. Sheu SS, Nauduri D, Anders MW. Targeting antioxidants to mitochondria: a new therapeutic direction. Biochim Biophys Acta. 2006;1762(2):256-65. (Pubitemid 43006031)
36. Klings ES, Farber HW. Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease. Respir Res. 2001;2 (5):280-285. (Pubitemid 34189652)
37. Metodiewa D, Jaiswal AK, Cenas N, Dickancaite E, Segura-Aguilar J. Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product. Free Radic Biol Med. 1999;26:107-116. (Pubitemid 29001498)
38. Watjen W, Michels G, Steffan B, et al. Low concentrations of flavonoids are protective in rat H4IIE cells whereas high concentrations cause DNA damage and apoptosis. J Nutr. 2005;135(3):525-531. (Pubitemid 40365213)
39. Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Rad Biol Med. 1996;20(7):933-956. (Pubitemid 26157509)
40. Galati G, Lin A, Sultan AM, O'Brien PJ. Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Rad Biol Med. 2006;40(4):570-580. (Pubitemid 43170808)
41. Raza H, John A. Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments. Toxicol Appl Pharmacol. 2005;207(3):212-220. (Pubitemid 41207914)
42. Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol. 1990;186(1-85). (Pubitemid 20279941)
43. Akoh CC, Min DB. Food lipids. Chemistry, nutrition and biotechnology.3rd edition. Boca raton:CRC press/Taylor and Francis group [Book]
44. Podmore ID, Griffiths HR, Herbert KE, Mistry N, Mistry P, Lunec J. Vitamin C exhibits pro-oxidant properties. Nature. 1998;392(6676):559. (Pubitemid 28207702)
45. Prieme H, Loft S, Nyyssonen K, Salonen JT, Poulsen HE. No effect of supplementation with vitamin E, ascorbic acid, or coenzyme Q10 on oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2′-deoxyguanosine excretion in smokers. Am J Clin Nutr. 1997;65(2):503-507. (Pubitemid 27130759)
46. Carr AC, Zhu BZ, Frei B. Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E). Circ Res. 2000;87(5):349-354.
47. Farbstein D, Kozak-Blickstein A, Levy AP. Antioxidant vitamins and their use in preventing cardiovascular disease. Molecules (Basel, Switzerland). 2010;15(11):8098-8110.
48. Halliwell B. Effect of diet on cancer development: is oxidative DNA damage a biomarker? Free Rad Biol Med. 2002;32(10):968-974. (Pubitemid 34465648)
49. Lairon D. Intervention studies on Mediterranean diet and cardiovascular risk. Mol Nutr Food Res. 2007;51(10):1209-1214. (Pubitemid 350013168)
50. Goralczyk R. Beta-carotene and lung cancer in smokers: review of hypotheses and status of research. Nutr Cancer. 2009;61(6):767-774.
51. Yeh SL, Wang HM, Chen PY, Wu TC. Interactions of betacarotene and flavonoids on the secretion of pro-inflammatory mediators in an in vitro system. Chem Biol Interact. 2009;179(2-3):386-393.
52. Leppala JM, Virtamo J, Fogelholm R, et al. Controlled trial of alpha-tocopherol and beta-carotene supplements on stroke incidence and mortality in male smokers. Arterioscler Thromb Vasc Biol. 2000;20(1):230-235. (Pubitemid 30048369)
53. Tatsuta T, Langer T. Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J. 2008;27(2):306-314. (Pubitemid 351161660)