5-Methyl phenazine-1-carboxylic acid: A novel bioactive metabolite by a rhizosphere soil bacterium that exhibits potent antimicrobial and anticancer activities

Chemico-Biological Interactions

Volumn 231, Issue , 2015, Pages 71-82

  Kennedy, R Kamaraj ^a   Naik, P Ravindra ^a   Veena, V ^a   Lakshmi, B S ^b   Lakshmi, Pragna ^a   Krishna, R ^a   Sakthivel, N ^a  

^a PONDICHERRY UNIVERSITY   (India)

^b ANNA UNIVERSITY   (India)

Author keywords

5 Methyl phenazine 1 carboxylic acid; Bcl 2 family proteins; betaine; Cytotoxic activity; Pseudomonas putida

Indexed keywords

5 METHYLPHENAZINE 1 CARBOXYLIC ACID BETAINE; PHENAZINE DERIVATIVE; PROTEIN BCL 2; PROTEIN BCL W; PROTEIN BCL XL; UNCLASSIFIED DRUG; 1-PHENAZINECARBOXYLIC ACID; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CASPASE 3;

ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DRUG CYTOTOXICITY; DRUG PROTEIN BINDING; DRUG STRUCTURE; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC50; INFRARED SPECTROSCOPY; LUNG CANCER CELL LINE; MASS SPECTROMETRY; MOLECULAR DOCKING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PSEUDOMONAS PUTIDA; RHIZOSPHERE BACTERIUM; SOIL MICROFLORA; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; NEOPLASMS; RHIZOSPHERE; TUMOR CELL LINE;

BACTERIA (MICROORGANISMS); PSEUDOMONAS PUTIDA;

ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; NEOPLASMS; PHENAZINES; PROTO-ONCOGENE PROTEINS C-BCL-2; PSEUDOMONAS PUTIDA; RHIZOSPHERE;

EID: 84924788182     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.03.002     Document Type: Article

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