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Volumn 24, Issue 5, 2015, Pages 1432-1440

Obesity and ischemic stroke modulate the methylation levels of KCNQ1 in white blood cells

Author keywords

[No Author keywords available]

Indexed keywords

CALDESMON; CALDESMON 1; DNA; POTASSIUM CHANNEL KCNQ1; UNCLASSIFIED DRUG; WT1 PROTEIN; CALMODULIN; CALMODULIN BINDING PROTEIN; GENETIC MARKER; KCNQ1 PROTEIN, HUMAN; METALLOPROTEINASE; WT1 PROTEIN, HUMAN;

EID: 84924455466     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu559     Document Type: Article
Times cited : (46)

References (63)
  • 2
    • 33846245504 scopus 로고    scopus 로고
    • Preventing stroke:saving lives around the world
    • Strong, K., Mathers, C. and Bonita, R. (2007) Preventing stroke:saving lives around the world. Lancet Neurol., 6, 182-187.
    • (2007) Lancet Neurol. , vol.6 , pp. 182-187
    • Strong, K.1    Mathers, C.2    Bonita, R.3
  • 4
    • 84884502183 scopus 로고    scopus 로고
    • Smoking, heart rate, and ischemic stroke: a population-based prospective cohort study among Inner Mongolians in China
    • Xu, T., Bu, X., Li, H., Zhang, M.,Wang, A., Tong,W., Sun, Y. and Zhang, Y. (2013) Smoking, heart rate, and ischemic stroke: a population-based prospective cohort study among Inner Mongolians in China. Stroke, 44, 2457-2461.
    • (2013) Stroke , vol.44 , pp. 2457-2461
    • Xu, T.1    Bu, X.2    Li, H.3    Zhang, M.4    Wang, A.5    Tong, W.6    Sun, Y.7    Zhang, Y.8
  • 5
    • 84888386774 scopus 로고    scopus 로고
    • Extended-release niacin therapy and risk of ischemic stroke in patients with cardiovascular disease: the Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcome (AIM-HIGH) trial
    • Teo, K.K., Goldstein, L.B., Chaitman, B.R., Grant, S., Weintraub, W.S., Anderson, D.C., Sila, C.A., Cruz-Flores, S., Padley, R.J., Kostuk, W.J. et al. (2013) Extended-release niacin therapy and risk of ischemic stroke in patients with cardiovascular disease: the Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcome (AIM-HIGH) trial. Stroke, 44, 2688-2693.
    • (2013) Stroke , vol.44 , pp. 2688-2693
    • Teo, K.K.1    Goldstein, L.B.2    Chaitman, B.R.3    Grant, S.4    Weintraub, W.S.5    Anderson, D.C.6    Sila, C.A.7    Cruz-Flores, S.8    Padley, R.J.9    Kostuk, W.J.10
  • 8
    • 84880744571 scopus 로고    scopus 로고
    • The netrin G1 gene rs628117 polymorphism is associated with ischemic stroke
    • Stepanyan, A., Zakharyan, R. and Boyajyan, A. (2013) The netrin G1 gene rs628117 polymorphism is associated with ischemic stroke. Neurosci. Lett., 549, 74-77.
    • (2013) Neurosci. Lett. , vol.549 , pp. 74-77
    • Stepanyan, A.1    Zakharyan, R.2    Boyajyan, A.3
  • 10
    • 34249275353 scopus 로고    scopus 로고
    • Phenotypic plasticity and the epigenetics of human disease
    • Feinberg, A.P. (2007) Phenotypic plasticity and the epigenetics of human disease. Nature, 447, 433-440.
    • (2007) Nature , vol.447 , pp. 433-440
    • Feinberg, A.P.1
  • 11
    • 84878106876 scopus 로고    scopus 로고
    • Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives
    • Milagro, F.I., Mansego, M.L., De Miguel, C. and Martinez, J.A. (2013) Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives. Mol. Aspects Med., 34, 782-812.
    • (2013) Mol. Aspects Med. , vol.34 , pp. 782-812
    • Milagro, F.I.1    Mansego, M.L.2    De Miguel, C.3    Martinez, J.A.4
  • 12
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller, M. (2008) Epigenetics in cancer. N. Engl. J. Med., 358, 1148-1159.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 13
    • 84883557907 scopus 로고    scopus 로고
    • TNF-alpha promoter methylation in peripheral white blood cells: relationship with circulating TNFalpha, truncal fat and n-6 PUFA intake in young women
    • Hermsdorff, H.H., Mansego, M.L., Campion, J., Milagro, F.I., Zulet, M.A. and Martinez, J.A. (2013) TNF-alpha promoter methylation in peripheral white blood cells: relationship with circulating TNFalpha, truncal fat and n-6 PUFA intake in young women. Cytokine, 64, 265-271.
    • (2013) Cytokine , vol.64 , pp. 265-271
    • Hermsdorff, H.H.1    Mansego, M.L.2    Campion, J.3    Milagro, F.I.4    Zulet, M.A.5    Martinez, J.A.6
  • 15
    • 79960372183 scopus 로고    scopus 로고
    • The epigenetic effects of antidepressant treatment on human prefrontal cortex BDNF expression
    • Chen, E.S., Ernst, C. andTurecki,G. (2011) The epigenetic effects of antidepressant treatment on human prefrontal cortex BDNF expression. Int. J. Neuropsychopharmacol., 14, 427-429.
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 427-429
    • Chen, E.S.1    Ernst, C.2    Turecki, G.3
  • 16
    • 78650112000 scopus 로고    scopus 로고
    • The emerging role of epigenetics in stroke: II. RNA regulatory circuitry
    • Qureshi, I.A. and Mehler, M.F. (2010) The emerging role of epigenetics in stroke: II. RNA regulatory circuitry. Arch. Neurol., 67, 1435-1441.
    • (2010) Arch. Neurol. , vol.67 , pp. 1435-1441
    • Qureshi, I.A.1    Mehler, M.F.2
  • 18
    • 84880922774 scopus 로고    scopus 로고
    • Synergy of homocysteine, microRNA, and epigenetics: a novel therapeutic approach for stroke
    • Kalani, A., Kamat, P.K., Tyagi, S.C. and Tyagi, N. (2013) Synergy of homocysteine, microRNA, and epigenetics: a novel therapeutic approach for stroke. Mol. Neurobiol., 48, 157-168.
    • (2013) Mol. Neurobiol. , vol.48 , pp. 157-168
    • Kalani, A.1    Kamat, P.K.2    Tyagi, S.C.3    Tyagi, N.4
  • 19
    • 79960124631 scopus 로고    scopus 로고
    • DNA methylation in white blood cells:association with risk factors in epidemiologic studies
    • Terry, M.B., Delgado-Cruzata, L., Vin-Raviv, N., Wu, H.C. and Santella, R.M. (2011) DNA methylation in white blood cells:association with risk factors in epidemiologic studies. Epigenetics, 6, 828-837.
    • (2011) Epigenetics , vol.6 , pp. 828-837
    • Terry, M.B.1    Delgado-Cruzata, L.2    Vin-Raviv, N.3    Wu, H.C.4    Santella, R.M.5
  • 21
    • 84884490191 scopus 로고    scopus 로고
    • Predictors of stroke in patients with impaired glucose tolerance: results fromthe Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial
    • Preiss, D., Giles, T.D., Thomas, L.E., Sun, J.L., Haffner, S.M., Holman, R.R., Standl, E., Mazzone, T., Rutten, G.E., Tognoni, G. et al. (2013) Predictors of stroke in patients with impaired glucose tolerance: results fromthe Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial. Stroke, 44, 2590-2593.
    • (2013) Stroke , vol.44 , pp. 2590-2593
    • Preiss, D.1    Giles, T.D.2    Thomas, L.E.3    Sun, J.L.4    Haffner, S.M.5    Holman, R.R.6    Standl, E.7    Mazzone, T.8    Rutten, G.E.9    Tognoni, G.10
  • 24
    • 84877032796 scopus 로고    scopus 로고
    • Impact of post-challenge hyperglycemia on clinical outcomes in Japanese patients with stable angina undergoing percutaneous coronary intervention
    • Kuramitsu, S., Yokoi, H., Domei, T., Nomura, A.,Watanabe, H., Yamaji, K., Soga, Y., Arita, T., Kondo, K., Shirai, S. et al. (2013) Impact of post-challenge hyperglycemia on clinical outcomes in Japanese patients with stable angina undergoing percutaneous coronary intervention. Cardiovasc. Diabetol., 12, 74.
    • (2013) Cardiovasc. Diabetol. , vol.12 , pp. 74
    • Kuramitsu, S.1    Yokoi, H.2    Domei, T.3    Nomura, A.4    Watanabe, H.5    Yamaji, K.6    Soga, Y.7    Arita, T.8    Kondo, K.9    Shirai, S.10
  • 25
    • 71749115105 scopus 로고    scopus 로고
    • Should more patients with acute ischaemic stroke receive thrombolytic treatment?
    • Wardlaw, J.M., Sandercock, P.A. and Murray, V. (2009) Should more patients with acute ischaemic stroke receive thrombolytic treatment? BMJ, 339, b4584.
    • (2009) BMJ , vol.339 , pp. b4584
    • Wardlaw, J.M.1    Sandercock, P.A.2    Murray, V.3
  • 27
    • 0028854369 scopus 로고
    • Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex
    • Jander, S., Kraemer, M., Schroeter, M.,Witte, O.W. and Stoll, G. (1995) Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex. J. Cereb. Blood Flow Metab., 15, 42-51.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 42-51
    • Jander, S.1    Kraemer, M.2    Schroeter, M.3    Witte, O.W.4    Stoll, G.5
  • 29
    • 64549119716 scopus 로고    scopus 로고
    • Inflammation, plasticity and real-time imaging after cerebral ischemia
    • Kriz, J. and Lalancette-Hebert, M. (2009) Inflammation, plasticity and real-time imaging after cerebral ischemia. Acta Neuropathol., 117, 497-509.
    • (2009) Acta Neuropathol. , vol.117 , pp. 497-509
    • Kriz, J.1    Lalancette-Hebert, M.2
  • 30
    • 84885435095 scopus 로고    scopus 로고
    • Peripheral polymorphonuclear leukocyte activation as a systemic inflammatory response in ischemic stroke
    • Mo, X., Li, T., Ji, G., Lu, W. and Hu, Z. (2013) Peripheral polymorphonuclear leukocyte activation as a systemic inflammatory response in ischemic stroke. Neurol. Sci., 34, 1509-1516.
    • (2013) Neurol. Sci. , vol.34 , pp. 1509-1516
    • Mo, X.1    Li, T.2    Ji, G.3    Lu, W.4    Hu, Z.5
  • 31
    • 84891666699 scopus 로고    scopus 로고
    • Blood spotlight on leukocytes and obesity
    • Carvalheira, J.B., Qiu, Y. and Chawla, A. (2013) Blood spotlight on leukocytes and obesity. Blood, 122, 3263-3267.
    • (2013) Blood , vol.122 , pp. 3263-3267
    • Carvalheira, J.B.1    Qiu, Y.2    Chawla, A.3
  • 32
    • 84872152102 scopus 로고    scopus 로고
    • When diet and exercise are not enough, think immunomodulation
    • Snyder-Cappione, J.E. and Nikolajczyk, B.S. (2013) When diet and exercise are not enough, think immunomodulation. Mol. Aspects Med., 34, 30-38.
    • (2013) Mol. Aspects Med. , vol.34 , pp. 30-38
    • Snyder-Cappione, J.E.1    Nikolajczyk, B.S.2
  • 36
    • 79954611176 scopus 로고    scopus 로고
    • A dual epigenomic approach for the search of obesity biomarkers:DNA methylation in relation to diet-induced weight loss
    • Milagro, F.I., Campion, J., Cordero, P., Goyenechea, E., Gomez-Uriz, A.M., Abete, I., Zulet, M.A. and Martinez, J.A. (2011) A dual epigenomic approach for the search of obesity biomarkers:DNA methylation in relation to diet-induced weight loss. FASEB J., 25, 1378-1389.
    • (2011) FASEB J. , vol.25 , pp. 1378-1389
    • Milagro, F.I.1    Campion, J.2    Cordero, P.3    Goyenechea, E.4    Gomez-Uriz, A.M.5    Abete, I.6    Zulet, M.A.7    Martinez, J.A.8
  • 37
    • 84870254039 scopus 로고    scopus 로고
    • Transcriptomic and epigenetic changes in the hypothalamus are involved in an increased susceptibility to a high-fat-sucrose diet in prenatally stressed female rats
    • Paternain, L., Batlle, M.A., De la Garza, A.L., Milagro, F.I., Martinez, J.A. and Campion, J. (2012) Transcriptomic and epigenetic changes in the hypothalamus are involved in an increased susceptibility to a high-fat-sucrose diet in prenatally stressed female rats. Neuroendocrinology, 96, 249-260.
    • (2012) Neuroendocrinology , vol.96 , pp. 249-260
    • Paternain, L.1    Batlle, M.A.2    De la Garza, A.L.3    Milagro, F.I.4    Martinez, J.A.5    Campion, J.6
  • 38
    • 84871127612 scopus 로고    scopus 로고
    • Associations of BDNF genotype and promoter methylation with acute and long-term stroke outcomes in an East Asian cohort
    • Kim, J.M., Stewart, R., Park, M.S., Kang, H.J., Kim, S.W., Shin, I. S., Kim, H.R., Shin, M.G., Cho, K.H. and Yoon, J.S. (2012) Associations of BDNF genotype and promoter methylation with acute and long-term stroke outcomes in an East Asian cohort. PLoS One, 7, e51280.
    • (2012) PLoS One , vol.7 , pp. e51280
    • Kim, J.M.1    Stewart, R.2    Park, M.S.3    Kang, H.J.4    Kim, S.W.5    Shin, I.S.6    Kim, H.R.7    Shin, M.G.8    Cho, K.H.9    Yoon, J.S.10
  • 40
    • 84884920554 scopus 로고    scopus 로고
    • Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes
    • Masliah, E., Dumaop, W., Galasko, D. and Desplats, P. (2013) Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes. Epigenetics, 8, 1030-1038.
    • (2013) Epigenetics , vol.8 , pp. 1030-1038
    • Masliah, E.1    Dumaop, W.2    Galasko, D.3    Desplats, P.4
  • 42
    • 79952335646 scopus 로고    scopus 로고
    • Diversification of caldesmon- linked actin cytoskeleton in cell motility
    • Mayanagi, T. and Sobue, K. (2011) Diversification of caldesmon- linked actin cytoskeleton in cell motility. Cell Adh. Migr., 5, 150-159.
    • (2011) Cell Adh. Migr. , vol.5 , pp. 150-159
    • Mayanagi, T.1    Sobue, K.2
  • 45
    • 84868328459 scopus 로고    scopus 로고
    • The association between KCNQ1 gene polymorphism and type 2 diabetes risk: a meta-analysis
    • Sun, Q., Song, K., Shen, X. and Cai, Y. (2012) The association between KCNQ1 gene polymorphism and type 2 diabetes risk: a meta-analysis. PLoS One, 7, e48578.
    • (2012) PLoS One , vol.7 , pp. e48578
    • Sun, Q.1    Song, K.2    Shen, X.3    Cai, Y.4
  • 46
    • 84896700083 scopus 로고    scopus 로고
    • Sudden death by stress:how far under the nerves should we dig to find out why LQT1 patients die?
    • Schwartz, P.J. and Volders, P.G. (2014) Sudden death by stress:how far under the nerves should we dig to find out why LQT1 patients die? J. Am. Coll. Cardiol., 63, 828-830.
    • (2014) J. Am. Coll. Cardiol. , vol.63 , pp. 828-830
    • Schwartz, P.J.1    Volders, P.G.2
  • 48
    • 84886298550 scopus 로고    scopus 로고
    • Epigenetics and the modulation of neuroinflammation
    • Garden, G.A. (2013) Epigenetics and the modulation of neuroinflammation. Neurotherapeutics, 10, 782-788.
    • (2013) Neurotherapeutics , vol.10 , pp. 782-788
    • Garden, G.A.1
  • 49
    • 84881006702 scopus 로고    scopus 로고
    • Association of weight regain with specific methylation levels in the NPY and POMC promoters in leukocytes of obese men: a translational study
    • Crujeiras, A.B., Campion, J., Diaz-Lagares, A., Milagro, F.I., Goyenechea, E., Abete, I., Casanueva, F.F. and Martinez, J.A. (2013) Association of weight regain with specific methylation levels in the NPY and POMC promoters in leukocytes of obese men: a translational study. Regul. Pept., 186, 1-6.
    • (2013) Regul. Pept. , vol.186 , pp. 1-6
    • Crujeiras, A.B.1    Campion, J.2    Diaz-Lagares, A.3    Milagro, F.I.4    Goyenechea, E.5    Abete, I.6    Casanueva, F.F.7    Martinez, J.A.8
  • 50
    • 77956819100 scopus 로고    scopus 로고
    • The suitability of matrix assisted laser desorption/ionization time of flight mass spectrometry in a laboratory developed test using cystic fibrosis carrier screening as a model
    • Farkas, D.H., Miltgen, N.E., Stoerker, J., van den Boom, D., Highsmith, W.E., Cagasan, L., McCullough, R., Mueller, R., Tang, L., Tynan, J. et al. (2010) The suitability of matrix assisted laser desorption/ionization time of flight mass spectrometry in a laboratory developed test using cystic fibrosis carrier screening as a model. J. Mol. Diagn., 12, 611-619.
    • (2010) J. Mol. Diagn. , vol.12 , pp. 611-619
    • Farkas, D.H.1    Miltgen, N.E.2    Stoerker, J.3    van den Boom, D.4    Highsmith, W.E.5    Cagasan, L.6    McCullough, R.7    Mueller, R.8    Tang, L.9    Tynan, J.10
  • 51
    • 79851501711 scopus 로고    scopus 로고
    • Role of hypoxiainducible factor-1alpha endothelin-1 and inducible nitric oxide synthase in the pathogenesis of hypoxia-induced pulmonary hypertension of the newborn
    • Wang, L., Zhu, Y.P. and Li, M.X. (2011) Role of hypoxiainducible factor-1alpha endothelin-1 and inducible nitric oxide synthase in the pathogenesis of hypoxia-induced pulmonary hypertension of the newborn. Zhongguo Dang Dai Er Ke Za Zhi, 13, 8-11.
    • (2011) Zhongguo Dang Dai Er Ke Za Zhi , vol.13 , pp. 8-11
    • Wang, L.1    Zhu, Y.P.2    Li, M.X.3
  • 52
    • 84880431946 scopus 로고    scopus 로고
    • Mammalian circadian clock: the roles of transcriptional repression and delay
    • Minami, Y., Ode, K.L. and Ueda, H.R. (2013) Mammalian circadian clock: the roles of transcriptional repression and delay. Handb. Exp. Pharmacol., 217, 359-377.
    • (2013) Handb. Exp. Pharmacol. , vol.217 , pp. 359-377
    • Minami, Y.1    Ode, K.L.2    Ueda, H.R.3
  • 53
    • 84875818662 scopus 로고    scopus 로고
    • Innate immunomodulation by lipophilic termini of lipopolysaccharide; synthesis of lipid As from Porphyromonas gingivalis and other bacteria and their immunomodulative responses
    • Fujimoto, Y., Shimoyama, A., Saeki, A., Kitayama, N., Kasamatsu, C., Tsutsui, H. and Fukase, K. (2013) Innate immunomodulation by lipophilic termini of lipopolysaccharide; synthesis of lipid As from Porphyromonas gingivalis and other bacteria and their immunomodulative responses. Mol. Biosyst., 9, 987-996.
    • (2013) Mol. Biosyst. , vol.9 , pp. 987-996
    • Fujimoto, Y.1    Shimoyama, A.2    Saeki, A.3    Kitayama, N.4    Kasamatsu, C.5    Tsutsui, H.6    Fukase, K.7
  • 55
    • 0032730230 scopus 로고    scopus 로고
    • Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group
    • Woo, D., Broderick, J.P., Kothari, R.U., Lu, M., Brott, T., Lyden, P.D., Marler, J.R. and Grotta, J.C. (1999) Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group. Stroke, 30, 2355-2359.
    • (1999) Stroke , vol.30 , pp. 2355-2359
    • Woo, D.1    Broderick, J.P.2    Kothari, R.U.3    Lu, M.4    Brott, T.5    Lyden, P.D.6    Marler, J.R.7    Grotta, J.C.8
  • 56
    • 12344259499 scopus 로고    scopus 로고
    • World Health Organisation-International Society of Hypertension (WHO/ISH) hypertension guidelines
    • Whitworth, J.A. and Chalmers, J. (2004)World Health Organisation-International Society of Hypertension (WHO/ISH) hypertension guidelines. Clin. Exp. Hypertens., 26, 747-752.
    • (2004) Clin. Exp. Hypertens. , vol.26 , pp. 747-752
    • Whitworth, J.A.1    Chalmers, J.2
  • 57
    • 12344330424 scopus 로고    scopus 로고
    • limmaGUI: a graphical user interface for linear modeling of microarray data
    • Wettenhall, J.M. and Smyth, G.K. (2004) limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics, 20, 3705-3706.
    • (2004) Bioinformatics , vol.20 , pp. 3705-3706
    • Wettenhall, J.M.1    Smyth, G.K.2
  • 58
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini, Y. and Hochberg, Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Statist. Soc. B, 57, 289-300.
    • (1995) J. R. Statist. Soc. B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 60
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Research0034-0034.11
    • Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A. and Speleman, F. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol., 3, Research0034-0034.11.
    • (2002) Genome Biol. , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 61
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak, K.J. and Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods, 25, 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


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