TNF-alpha promoter methylation in peripheral white blood cells: Relationship with circulating TNFα, truncal fat and n-6 PUFA intake in young women

Cytokine

Volumn 64, Issue 1, 2013, Pages 265-271

  Hermsdorff, H H ^a   Mansego, M L ^b,c   Campion J ^b,c   Milagro, F I ^b,c   Zulet, M A ^b,c   Martinez J A ^b,c  

^a FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

^b UNIVERSITY OF NAVARRA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Body fat distribution; DNA methylation; Epigenetics; Leucocytes; TNF alpha

Indexed keywords

5 METHYLCYTOSINE; DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; OMEGA 6 FATTY ACID; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BODY FAT; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; CROSS-SECTIONAL STUDY; DNA METHYLATION; FAT INTAKE; FEMALE; HUMAN; HUMAN CELL; INSULIN BLOOD LEVEL; LEUKOCYTE; OBESITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; TNFA GENE;

BODY FAT DISTRIBUTION; DNA METHYLATION; EPIGENETICS; LEUCOCYTES; TNF-ALPHA;

5-METHYLCYTOSINE; ADIPOSE TISSUE; ADIPOSITY; ADOLESCENT; ADULT; BODY COMPOSITION; BODY FAT DISTRIBUTION; BODY WEIGHT; CHOLESTEROL, HDL; CROSS-SECTIONAL STUDIES; DIET; DIETARY FATS; DNA METHYLATION; FATTY ACIDS, UNSATURATED; FEMALE; FOOD; HUMANS; INFLAMMATION; INSULIN; LEUKOCYTES; PROMOTER REGIONS, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84883557907     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2013.05.028     Document Type: Article

References (63)

1. Martí A., Martínez-González M.A., Martínez J.A. Interaction between genes and lifestyle factors on obesity. Proc Nutr Soc 2008, 67:1-8.
2. Fain J.N. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm 2006, 74:443-477.
3. Ghanim H., Aljada A., Hofmeyer D., Syed T., Mohanty P., Dandona P. Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation 2004, 110:1564-1571.
4. Hermsdorff H.H.M., Puchau B., Zulet M.A., Martínez J.A. Association of body fat distribution with proinflammatory gene expression in peripheral blood mononuclear cells from young adult subjects. OMICS 2010, 14:297-307.
5. Ayer J.G., Song C., Steinbeck K., Celermajer D.S., Ben Freedman S. Increased tissue factor activity in monocytes from obese young adults. Clin Exp Pharmacol Physiol 2010, 37:1049-1054.
6. Catalán V., Gómez-Ambrosi J., Rodríguez A., Ramírez B., Silva C., Rotellar F., et al. Association of increased visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity. Nutr Metab Cardiovasc Dis 2011, 21:245-253.
7. Abete I., Goyenechea E., Zulet M.A., Martínez J.A. Obesity and metabolic syndrome: potential benefit from specific nutritional components. Nutr Metab Cardiovasc Dis 2012, 21(Suppl 2):B1-B15.
8. Tai C.C., Ding S.T. N-3 polyunsaturated fatty acids regulate lipid metabolism through several inflammation mediators: mechanisms and implications for obesity prevention. J Nutr Biochem 2010, 21:357-363.
9. Martinez J.A., Cordero P., Campion J., Milagro F.I. Interplay of early-life nutritional programming on obesity, inflammation and epigenetic outcomes. Proc Nutr Soc 2012, 71:276-283.
10. Campion J., Milagro F.I., Goyenechea E., Martinez J.A. TNF-alpha promoter methylation as a predictive biomarker for weight-loss response. Obesity (Silver Spring) 2009, 17:1293-1297.
11. Lim U., Song M.A. Dietary and lifestyle factors of DNA methylation. Methods Mol Biol 2012, 863:359-376.
12. Zhang F.F., Santella R.M., Wolff M., Kappil M.A., Markowitz S.B., Morabia A. White blood cell global methylation and IL-6 promoter methylation in association with diet and lifestyle risk factors in a cancer-free population. Epigenetics 2012, 7:606-614.
13. Odrowaz-Sypniewska G. Markers of pro-inflammatory and pro-thrombotic state in the diagnosis of metabolic syndrome. Adv Med Sci 2007, 52:246-250.
14. Zulet M.A., Puchau B., Navarro C., Marti A., Martínez J.A. Inflammatory biomarkers: the link between obesity and associated pathologies. Nutr Hosp 2007, 22:511-527.
15. Vaccarino L., Vitale S., Caruso M., Palmeri M., Scola L., Bova M., et al. Myocardial infarction marker levels are influenced by prothrombin and tumor necrosis factor-alpha gene polymorphisms in young patients. Cytokine 2013, 61:218-222.
16. Welsh P., Woodward M., Rumley A., Lowe G. Associations of circulating TNFα and IL-18 with myocardial infarction and cardiovascular risk markers: the Glasgow Myocardial Infarction Study. Cytokine 2009, 47:143-147.
17. de Batlle J., Sauleda J., Balcells E., Gomez F.P., Mendez M., Rodriguez E., et al. Association between Omega3 and Omega6 fatty acid intakes and serum inflammatory markers in COPD. J Nutr Biochem 2012, 23:817-821.
18. Mozaffarian D., Pischon T., Hankinson S.E., Rifai N., Joshipura K., Willett W.C., et al. Dietary intake of trans fatty acids and systemic inflammation in women. Am J Clin Nutr 2004, 79:606-612.
19. Pischon T., Hankinson S.E., Hotamisligil G.S., Rifai N., Willett W.C., Rimm E.B. Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women. Circulation 2003, 108:155-160.
20. Han L.Y., Guo Z.Y., Fan Y.C., Wang K. Hypomethylation of TNF-alpha gene promoter in the patients with acute-on-chronic hepatitis B liver failure. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2011, 25:368-370.
21. Nimmo E.R., Prendergast J.G., Aldhous M.C., Kennedy N.A., Henderson P., Drummond H.E., et al. Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway. Inflamm Bowel Dis 2012, 18:889-899.
22. Pieper H.C., Evert B.O., Kaut O., Riederer P.F., Waha A., Wullner U. Different methylation of the TNF-alpha promoter in cortex and substantia nigra: implications for selective neuronal vulnerability. Neurobiol Dis 2008, 32:521-527.
23. El Gazzar M., Yoza B.K., Chen X., Garcia B.A., Young N.L., McCall C.E. Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. Mol Cell Biol 2009, 29:1959-1971.
24. Cordero P., Campión J., Milagro F.I., Goyenechea E., Steemburgo T., Javierre B.M., et al. Leptin and TNF-alpha promoter methylation levels measured by MSP could predict the response to a low-calorie diet. J Physiol Biochem 2011, 67:463-470.
25. Milagro F.I., Campion J., Cordero P., Goyenechea E., Gomez-Uriz A.M., Abete I., et al. A dual epigenomic approach for the search of obesity biomarkers: DNA methylation in relation to diet-induced weight loss. FASEB J 2011, 25:1378-1389.
26. Zhu J.G., Xia L., Ji C.B., Zhang C.M., Zhu G.Z., Shi C.M., et al. Differential DNA methylation status between human preadipocytes and mature adipocytes. Cell Biochem Biophys 2012, 63:1-15. 10.1007/s12013-012-9336-3.
27. Gowers I.R., Walters K., Kiss-Toth E., Read R.C., Duff G.W., Wilson A.G. Age-related loss of CpG methylation in the tumour necrosis factor promoter. Cytokine 2011, 56:792-797.
28. Willett W.C. Nutritional epidemiology 1998, Oxford University Press, New York. 2nd ed.
29. Hermsdorff H.H.M., Zulet M.A., Puchau B., Bressan J., Martínez J.A. Association of retinol-binding protein-4 with dietary selenium intake and other lifestyle features in young healthy women. Nutrition 2009, 25:392-399.
30. Ketel I.J., Volman M.N., Seidell J.C., Stehouwer C.D., Twisk J.W., Lambalk C.B. Superiority of skinfold measurements and waist over waist-to-hip ratio for determination of body fat distribution in a population-based cohort of Caucasian Dutch adults. Eur J Endocrinol 2007, 156:655-661.
31. Durnin J.V., Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 1974, 32:77-97.
32. Siri W.E. The gross composition of the body. Adv Biol Med Phys 1956, 4:239-280.
33. de la Fuente-Arrillaga C., Ruiz Z.V., Bes-Rastrollo M., Sampson L., Martinez-Gonzalez M.A. Reproducibility of an FFQ validated in Spain. Public Health Nutr 2010, 13:1364-1372.
34. Mataix J. Tabla de composición de alimentos 2009, Universidad de Granada, Granada. 5th ed.
35. Moreiras O., Carbajal A., Cabrera L., Cuadrado C. Tabla de composición de alimentos 2010, Ediciones Pirámide, Madrid. 13th ed.
36. Hermsdorff H.H.M., Zulet M.A., Puchau B., Martínez J.A. Fruit and vegetable consumption and proinflammatory gene expression from peripheral blood mononuclear cells in young adults: a translational study. Nutr Metab (Lond) 2010, 7:42.
37. Zulet M.A., Puchau B., Hermsdorff H.H.M., Navarro C., Martínez J.A. Dietary selenium intake is negatively associated with serum sialic acid and metabolic syndrome features in healthy young adults. Nutr Res 2009, 29:41-48.
38. Whitworth J.A., Chalmers J. World health organisation-international society of hypertension (WHO/ISH) hypertension guidelines. Clin Exp Hypertens 2004, 26:747-752.
39. Hermsdorff H.H.M., Zulet M.A., Puchau B., Martínez J.A. Central adiposity rather than total adiposity measurements are specifically involved in the inflammatory status from healthy young adults. Inflammation 2011, 34:161-170.
40. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
41. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
42. Xu H., Uysal K.T., Becherer J.D., Arner P., Hotamisligil G.S. Altered tumor necrosis factor-alpha (TNF-α) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity. Diabetes 2002, 51:1876-1883.
43. Antuna-Puente B., Feve B., Fellahi S., Bastard J.P. Adipokines: the missing link between insulin resistance and obesity. Diabetes Metab 2008, 34:2-11.
44. Rana J.S., Nieuwdorp M., Jukema J.W., Kastelein J.J. Cardiovascular metabolic syndrome - an interplay of, obesity, inflammation, diabetes and coronary heart disease. Diabetes Obes Metab 2007, 9:218-232.
45. Saddar S., Mineo C., Shaul P.W. Signaling by the high-affinity HDL receptor scavenger receptor B type I. Arterioscler Thromb Vasc Biol 2010, 30:144-150.
46. Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005, 434:772-777.
47. Zhu W., London N.R., Gibson C.C., Davis C.T., Tong Z., Sorensen L.K., et al. Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability. Nature 2012, 492:252-255.
48. Yin K., Chen W.J., Zhou Z.G., Zhao G.J., Lv Y.C., Ouyang X.P., et al. Apolipoprotein A-I inhibits CD40 proinflammatory signaling via ATP-binding cassette transporter A1-mediated modulation of lipid raft in macrophages. J Atheroscler Thromb 2012, 19:823-836.
49. Hivert M.F., Sullivan L.M., Shrader P., Fox C.S., Nathan D.M., D'Agostino R.B., et al. The association of tumor necrosis factor alpha receptor 2 and tumor necrosis factor alpha with insulin resistance and the influence of adipose tissue biomarkers in humans. Metabolism 2010, 59:540-546.
50. Rajala M.W., Scherer P.E. Minireview: the adipocyte - at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 2003, 144:3765-3773.
51. Quandt K., Frech K., Karas H., Wingender E., Werner T. MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 1995, 23:4878-4884.
52. Burnett E., Christensen J., Tattersall P. A consensus DNA recognition motif for two KDWK transcription factors identifies flexible-length, CpG-methylation sensitive cognate binding sites in the majority of human promoters. J Mol Biol 2001, 314:1029-1039.
53. Seifert A., Katschinski D.M., Tonack S., Fischer B., Navarrete Santos A. Significance of prolyl hydroxylase 2 in the interference of aryl hydrocarbon receptor and hypoxia-inducible factor-1α signaling. Chem Res Toxicol 2008, 21:341-348.
54. Imtiyaz H.Z., Simon M.C. Hypoxia-inducible factors as essential regulators of inflammation. Curr Top Microbiol Immunol 2010, 345:105-120.
55. Liu F.Q., Liu Y., Lui V.C., Lamb J.R., Tam P.K., Chen Y. Hypoxia modulates lipopolysaccharide induced TNF-alpha expression in murine macrophages. Exp Cell Res 2008, 314:1327-1336.
56. Bohn S.K., Myhrstad M.C., Thoresen M., Holden M., Karlsen A., Tunheim S.H., et al. Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers. BMC Med 2010, 8:54.
57. Ugocsai P., Hohenstatt A., Paragh G., Liebisch G., Langmann T., Wolf Z., et al. HIF-1beta determines ABCA1 expression under hypoxia in human macrophages. Int J Biochem Cell Biol 2010, 42:241-252.
58. Jiménez-Gómez Y., López-Miranda J., Blanco-Colio L.M., Marin C., Pérez-Martínez P., Ruano J., et al. Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men. Atherosclerosis 2009, 204:e70-e76.
59. Kanuri G., Spruss A., Wagnerberger S., Bischoff S.C., Bergheim I. Role of tumor necrosis factor alpha (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice. J Nutr Biochem 2010, 22:527-534.
60. Dangardt F., Osika W., Chen Y., Nilsson U., Gan L.M., Gronowitz E., et al. Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents. Atherosclerosis 2010, 212:580-585.
61. James M.J., Gibson R.A., Cleland L.G. Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr 2000, 71:343S-348S.
62. Calder P.C. Polyunsaturated fatty acids and inflammatory processes: new twists in an old tale. Biochimie 2009, 91:791-795.
63. Gillies P.J., Bhatia S.K., Belcher L.A., Hannon D.B., Thompson J.T., Vanden Heuvel J.P. Regulation of inflammatory and lipid metabolism genes by eicosapentaenoic acid-rich oil. J Lipid Res 2012, 53:1679-1689.