Role of hypoxia-inducible factor-1α endothelin-1 and inducible nitric oxide synthase in the pathogenesis of hypoxia-induced pulmonary hypertension of the newborn

Chinese Journal of Contemporary Pediatrics

Volumn 13, Issue 1, 2011, Pages 8-11

  Wang, Li ^a   Zhu, Yan Ping ^a   Li, Ming Xia ^a  

^a XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Endothelin 1; Hypoxia induced pulmonary hypertension; Hypoxia inducible factor 1 ; Inducible nitric oxide synthase; Neonate

Indexed keywords

ENDOTHELIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HOSPITALIZED INFANT; HUMAN; HYPOXIA; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN DISEASE; PATHOGENESIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PULMONARY HYPERTENSION;

ANOXIA; ENDOTHELIN-1; FEMALE; HUMANS; HYPERTENSION, PULMONARY; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFANT, NEWBORN; MALE; NITRIC OXIDE SYNTHASE TYPE II;

EID: 79851501711     PISSN: 10088830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. He ZH, Dai AG, Zhang XF, Tan XW. Expressions of hypoxia inducible factor-1 alpha and inducible nitric oxide synthase gene in the development of hypoxic pulmonary hypertension in rats[J]. Clin Rehab Tissue Eng Res, 2007,11(36):7290-7294.
2. McQuillan BM, Picard MH, Leavitt M, Weyman AE. Clinical correlates and reference intervals for pulmonary artery systolic pressure among echocardiographically normal subjects[J]. Circulation, 2001,104(23):2797-2802. (Pubitemid 33126653)
3. Simonneau G, Galie N, Rubin LJ, Langleben D, Seeger W, Domenighetti G, et al. Clinical classification of pulmonary hypertension[J]. J Am Coll Cardiol, 2004,43(12 Suppl S):5S-12S.
4. Stephen B, Dalai P, Berger M, SchweitaerP, Hecht S. Noninvasive estimation of pulmonary artery diastolic pressure in patients with tricuspid regurgitation by Doppler echocardiography[J]. Chest, 1999,116(1):73-77. (Pubitemid 29340263)
5. Abbas AE, Fortuin FD, Schiller NB, Appleton CP, Moreno CA, Lester SJ. Echocardiographic determination of mean pulmonary artery pressure[J]. Am J Cardiol, 2003,92(11):1373-1376. (Pubitemid 37431160)
6. Ruas JL, Lendahl U, Poellinger L. Modulation of vascular gene expression by hypoxia[J]. Curr Opin Lipidol, 2007,18(5):508-514.
7. Rajatapiti P, van der Horst IW, de Rooij JD, Tran MG, Maxwell PH, Tibboel D, et al. Expression of hypoxia-inducible factors in normal human lung development[J]. Pediatr Dev Pathol, 2008,11(3):193-199.
8. Schindler MB, Hislop AA, Haworth SG. Porcine pulmonary artery and bronchial responses to endothelin-1 and norepinephrine on recovery from hypoxic pulmonary hypertension[J]. Pediatr Res, 2006,60(1):71-76. (Pubitemid 44297616)
9. Hu R, Dai A, Tan S. Hypoxia-inducible factor 1 alpha upregulates the expression of inducible nitric oxide synthase gene in pulmonary arteries of hypoxic rat[J]. Chin Med J(Engl), 2002,115(12):1833-1837. (Pubitemid 36105062)
10. Jung F, Palmer LA, Zhou N, Johns RA. Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes[J]. Circ Res, 2000,86(3):319-325. (Pubitemid 30108826)