Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERα-dependent in ERα-negative human breast cancer cells

Molecular and Cellular Endocrinology

Volumn 406, Issue , 2015, Pages 102-114

  Sinha, Sonam ^a   Shukla, Samriddhi ^a   Khan, Sajid ^a   Tollefsbol, Trygve O ^b   Meeran, Syed M ^a,c  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

Breast cancer; Epigenetics; Estrogen receptor; Green tea; Sulforaphane; Tumor suppressor genes

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYCLIN DEPENDENT KINASE INHIBITOR 1; ESTROGEN RECEPTOR ALPHA; KLOTHO PROTEIN; POLYPHENOL DERIVATIVE; SULFORAPHANE; VORINOSTAT; BETA GLUCURONIDASE; CHROMATIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; ESTROGEN RECEPTOR ALPHA, HUMAN; HISTONE; ISOTHIOCYANIC ACID DERIVATIVE; POLYPHENOL; SOMATOMEDIN C; SULFORAFAN; TEA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYCLIN DEPENDENT KINASE INHIBITOR 1 GENE; DRUG POTENTIATION; EPIGENETICS; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; KLOTHO GENE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TUMOR SUPPRESSOR GENE; BREAST TUMOR; CELL CYCLE CHECKPOINT; CHEMISTRY; CHROMATIN; DIET SUPPLEMENTATION; DNA METHYLATION; DRUG EFFECTS; FEMALE; GENETIC EPIGENESIS; GENETICS; METABOLISM; PROMOTER REGION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TEA; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CHROMATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DIETARY SUPPLEMENTS; DNA METHYLATION; EPIGENESIS, GENETIC; ESTROGEN RECEPTOR ALPHA; FEMALE; GLUCURONIDASE; HISTONES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; ISOTHIOCYANATES; POLYPHENOLS; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; TEA;

EID: 84924405971     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.02.020     Document Type: Article

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