Downregulation of IGF-IR expression by RNAi inhibits proliferation and enhances chemosensitization of human colon cancer cells

International Journal of Colorectal Disease

Volumn 25, Issue 1, 2010, Pages 9-16

  Yavari, Kamal ^a   Taghikhani, Mohammad ^a   Ghannadi Maragheh, Mohammad ^b   Mesbah Namin, Seyed A ^a   Babaei, Mohammad Hossein ^b  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b Nuclear Sciences and Technology Research Institute   (Iran)

Author keywords

Cell proliferation; Chemosensitization; Colon cancer; IGF IR; Short hairpin RNA interference

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; DNA DIRECTED RNA POLYMERASE III; FLUOROURACIL; PLASMID VECTOR; SHORT HAIRPIN RNA; SOMATOMEDIN C RECEPTOR;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CHEMOSENSITIZATION; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RNA INTERFERENCE; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

CELL LINE, TUMOR; CELL PROLIFERATION; CLONING, MOLECULAR; COLONIC NEOPLASMS; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VECTORS; HUMANS; MICROSCOPY, FLUORESCENCE; PLASMIDS; RECEPTOR, IGF TYPE 1; RNA INTERFERENCE; RNA, MESSENGER; TRANSFORMATION, GENETIC;

EID: 72349089859     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-009-0783-2     Document Type: Article

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