Vitamin D3 metabolites enhance the NLRP3-dependent secretion of IL-1β from human THP-1 monocytic cells

Journal of Cellular Biochemistry

Volumn 116, Issue 5, 2015, Pages 711-720

  Tulk, Sarah E ^a   Liao, Kuo Chieh ^a   Muruve, Daniel A ^a   Li, Yan ^a   Beck, Paul L ^a   MacDonald, Justin A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

1; 25 DIHYDROXY VITAMIN D3; INNATE IMMUNITY; INTERLEUKIN 1 ; MACROPHAGE; NLR; NOD LIKE RECEPTOR; VDR

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ADENOSINE TRIPHOSPHATASE; CALCITRIOL; CASPASE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CHOLESTANETRIOL 26 MONOOXYGENASE; COLECALCIFEROL; COLECALCIFEROL 24 HYDROXYLASE; CRYOPYRIN; GLIBENCLAMIDE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; PROCASPASE 1; PROTEIN PRECURSOR; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; CALCITRIOL RECEPTOR; CARRIER PROTEIN; CASPASE INHIBITOR; CYP27A1 PROTEIN, HUMAN; N-ACETYL-TYROSYL-VALYL-ALANYL-ASPARTYL CHLOROMETHYL KETONE; NITRILE; NLRP3 PROTEIN, HUMAN; PEPTIDE CHLOROMETHYL KETONE; SULFONE;

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL STIMULATION; CELLULAR SECRETION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; METABOLISM; SECRETION (PROCESS);

CLOSTRIDIUM DIFFICILE;

AMINO ACID CHLOROMETHYL KETONES; CARRIER PROTEINS; CASPASE 1; CASPASE INHIBITORS; CHOLECALCIFEROL; CHOLESTANETRIOL 26-MONOOXYGENASE; GLYBURIDE; HUMANS; INTERLEUKIN-1BETA; MONOCYTES; NITRILES; RECEPTORS, CALCITRIOL; SULFONES;

EID: 84924405606     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24985     Document Type: Article

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