Vitamin D controls murine and human plasmacytoid dendritic cell function

Journal of Investigative Dermatology

Volumn 134, Issue 5, 2014, Pages 1255-1264

  Karthaus, Nina ^a   Van Spriel, Annemiek B ^a   Looman, Maaike W G ^a   Chen, Shuo ^a   Spilgies, Lisanne M ^a   Lieben, Liesbet ^b   Carmeliet, Geert ^b   Ansems, Marleen ^a   Adema, Gosse J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIFEDIOL; CALCITRIOL; COLECALCIFEROL; CYP 24 A1; CYP 27 B1; CYTOCHROME; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 5; MESSENGER RNA; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL FUNCTION; CYTOKINE RELEASE; DERMATITIS; GENE TARGETING; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; MIXED LYMPHOCYTE REACTION; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIASIS; SIGNAL TRANSDUCTION; SPLEEN; T LYMPHOCYTE; TH1 CELL; UPREGULATION; VITAMIN METABOLISM;

ANIMALS; CALCIFEDIOL; CALCITRIOL; DENDRITIC CELLS; DERMATOLOGIC AGENTS; HUMANS; INTERFERON-GAMMA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PSORIASIS; RECEPTORS, CALCITRIOL; SIGNAL TRANSDUCTION; TH1 CELLS; VITAMIN D;

EID: 84900852006     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.501     Document Type: Article

References (46)

1. Adorini L. Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting autoimmune diabetes Ann N Y Acad Sci 987 2003 258 261
2. Albanesi C. Scarponi C. Bosisio D. Immune functions and recruitment of plasmacytoid dendritic cells in psoriasis Autoimmunity 43 2010 215 219
3. Albanesi C. Scarponi C. Pallotta S. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment J Exp Med 206 2009 249 258
4. Baccala R. Gonzalez-Quintial R. Blasius A.L. Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus Proc Natl Acad Sci USA 110 2013 2940 2945
5. Barletta F. Freedman L.P. Christakos S. Enhancement of VDR-mediated transcription by phosphorylation: correlation with increased interaction between the VDR and DRIP205, a subunit of the VDR-interacting protein coactivator complex Mol Endocrinol 16 2002 301 314
6. Berer A. Stockl J. Majdic O. 1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro Exp Hematol 28 2000 575 583
7. Chuma M. Endo-Umeda K. Shimba S. Hairless modulates ligand-dependent activation of the vitamin D receptor-retinoid X receptor heterodimer Biol Pharm Bull 35 2012 582 587
8. Dam T.N. Kang S. Nickoloff B.J. 1Alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice J Invest Dermatol 113 1999 1082 1089
9. Daniel C. Sartory N.A. Zahn N. Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile J Pharmacol Exp Ther 324 2008 23 33
10. Ferreira G.B. van Etten E. Verstuyf A. 1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo Diabetes Metab Res Rev 27 2011 933 941
11. Gottfried E. Rehli M. Hahn J. Monocyte-derived cells express CYP27A1 and convert vitamin D3 into its active metabolite Biochem Biophy Res Commun 349 2006 209 213
12. Hontelez S. Karthaus N. Looman M.W. DC-SCRIPT regulates glucocorticoid receptor function and expression of its target GILZ in dendritic cells J Immunol 190 2013 3172 3179
13. Janjetovic Z. Tuckey R.C. Nguyen M.N. 20,23-Dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytes J Cell Physiol 223 2010 36 48
14. Janjetovic Z. Zmijewski M.A. Tuckey R.C. 20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes PLoS One 4 2009 e5988
15. Jeffery L.E. Burke F. Mura M. 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3 J Immunol 183 2009 5458 5467
16. Kamen D. Aranow C. Vitamin D in systemic lupus erythematosus Curr Opin Rheumatol 20 2008 532 537
17. Karthaus N. Hontelez S. Looman M.W. Nuclear receptor expression patterns in murine plasmacytoid and conventional dendritic cells Mol Immunol 55 2013 409 417
18. Kongsbak M. Levring T.B. Geisler C. The vitamin d receptor and T cell function Front Immunol 4 2013 148
19. Kragballe K. Calcipotriol: a new drug for topical psoriasis treatment Pharmacol Toxicol 77 1995 241 246
20. Lande R. Gregorio J. Facchinetti V. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide Nature 449 2007 564 569
21. Lebwohl M. Psoriasis Lancet 361 2003 1197 1204
22. Lieben L. Masuyama R. Torrekens S. Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D–induced inhibition of bone mineralization J Clin Invest 122 2012 1803 1815
23. Miteva M. Psoriasis: targeting therapy towards the inflammatory cascade Am J Clin Dermatol 11 Suppl 1 2010 11 13
24. Nestle F.O. Conrad C. Tun-Kyi A. Plasmacytoid predendritic cells initiate psoriasis through interferon-α production J Exp Med 202 2005 135 143
25. Nierkens S. den Brok M.H. Garcia Z. Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells Cancer Res 71 2011 6428 6437
26. Nikolic T. Roep B.O. Regulatory multitasking of tolerogenic dendritic cells - lessons taken from vitamin d3-treated tolerogenic dendritic cells Front Immunol 4 2013 113
27. Oquendo M. Abramovits W. Morrell P. Topical vitamin D analogs available to treat psoriasis Skinmed 10 2012 356 360
28. Penna G. Amuchastegui S. Giarratana N. 1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells J Immunol 178 2007 145 153
29. Penna G. Roncari A. Amuchastegui S. Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3 Blood 106 2005 3490 3497
30. Piemonti L. Monti P. Sironi M. Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells J Immunol 164 2000 4443 4451
31. Reichrath J. Perez A. Muller S.M. Topical calcitriol (1,25-dihydroxyvitamin D3) treatment of psoriasis: an immunohistological evaluation Acta Dermato-Venereologica 77 1997 268 272
32. Ricceri F. Pescitelli L. Tripo L. Deficiency of serum concentration of 25-hydroxyvitamin D correlates with severity of disease in chronic plaque psoriasis J Am Acad Dermatol 68 2013 511 512
33. Sakthiswary R. Raymond A.A. The clinical significance of vitamin D in systemic lupus erythematosus: a systematic review PLoS One 8 2013 e55275
34. Sigmundsdottir H. Pan J. Debes G.F. DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27 Nat Immunol 8 2007 285 293
35. Slominski A.T. Kim T.-K. Shehabi H.Z. In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1 FASEB J 26 2012 3901 3915
36. Széles L. Keresztes G. Töröcsik D. 1,25-Dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype J Immunol 182 2009 2074 2083
37. Tel J. Aarntzen E.H. Baba T. Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients Cancer Res 73 2013 1063 1075
38. Tel J. Benitez-Ribas D. Hoosemans S. DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells Eur J Immunol 41 2011 1014 1023
39. Tel J. Schreibelt G. Sittig S.P. Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets Blood 121 2013 459 467
40. Teunissen M.B. Haniffa M. Collin M.P. Insight into the immunobiology of human skin and functional specialization of skin dendritic cell subsets to innovate intradermal vaccination design Curr Top Microbiol Immunol 351 2012 25 76
41. Tremezaygues L. Reichrath J. Vitamin D analogs in the treatment of psoriasis: where are we standing and where will we be going? Dermato-Endocrinology 3 2011 180 186
42. Unger W.W. Laban S. Kleijwegt F.S. Induction of Treg by monocyte-derived DC modulated by vitamin D3 or dexamethasone: differential role for PD-L1 Eur J Immunol 39 2009 3147 3159
43. Van Cromphaut S.J. Dewerchin M. Hoenderop J.G. Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects Proc Natl Acad Sci USA 98 2001 13324 13329
44. White J.H. Vitamin D metabolism and signaling in the immune system Rev Endocr Metab Disord 13 2012 21 29
45. Wollenberg A. Wagner M. Gunther S. Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases J Invest Dermatol 119 2002 1096 1102
46. Yanofsky V.R. Mitsui H. Felsen D. Understanding dendritic cells and their role in cutaneous carcinoma and cancer immunotherapy Clin Dev Immunol 2013 2013 624123