Are there genetic paths common to obesity, cardiovascular disease outcomes, and cardiovascular risk factors?

Circulation Research

Volumn 116, Issue 5, 2015, Pages 909-922

  Rankinen, Tuomo ^a   Sarzynski, Mark A ^a   Ghosh, Sujoy ^a,b   Bouchard, Claude ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

Cluster analysis; Gene networks; Genetic pleiotropism

Indexed keywords

C REACTIVE PROTEIN; FARNESOID X RECEPTOR; LIVER X RECEPTOR; RETINOID X RECEPTOR;

BLOOD PRESSURE; BODY MASS; CARDIOMETABOLIC RISK; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CORONARY ARTERY DISEASE; ENHANCER REGION; FATTY LIVER; GENETIC ASSOCIATION; GENETIC VARIABILITY; HERITABILITY; HUMAN; META ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OUTCOME ASSESSMENT; PILOT STUDY; PLEIOTROPY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; CARDIOVASCULAR DISEASES; COMORBIDITY; CORONARY DISEASE; DEVELOPED COUNTRY; DYSLIPIDEMIAS; EPISTASIS; FEMALE; GENE REGULATORY NETWORK; GENETICS; MALE; METABOLIC SYNDROME X; MULTIFACTORIAL INHERITANCE; QUANTITATIVE TRAIT; SEDENTARY LIFESTYLE; SEX RATIO; SMOKING; TREATMENT OUTCOME; TWINS;

CARDIOVASCULAR DISEASES; COMORBIDITY; CORONARY DISEASE; DEVELOPED COUNTRIES; DISEASES IN TWINS; DYSLIPIDEMIAS; ENHANCER ELEMENTS, GENETIC; EPISTASIS, GENETIC; FEMALE; GENE REGULATORY NETWORKS; GENETIC PLEIOTROPY; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; METABOLIC SYNDROME X; MULTIFACTORIAL INHERITANCE; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE; RISK FACTORS; SEDENTARY LIFESTYLE; SEX DISTRIBUTION; SMOKING; TREATMENT OUTCOME; TWIN STUDIES AS TOPIC;

EID: 84924388081     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.302888     Document Type: Review

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