메뉴 건너뛰기




Volumn 2015, Issue , 2015, Pages

Prospects of HA-based universal influenza vaccine

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; NEUTRALIZING ANTIBODY; PEPTIDE VACCINE; HEMAGGLUTININ; VIRUS ANTIBODY;

EID: 84924308737     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/414637     Document Type: Review
Times cited : (41)

References (143)
  • 1
    • 67949097373 scopus 로고    scopus 로고
    • Prevention and control of seasonal influenza with vaccines: Recommendations of the Advisory Committee on Immunization Practices (ACIP)
    • A. E. Fiore, D. K. Shay, K. Broder et al., "Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP)," Morbidity and MortalityWeekly Report, vol. 58, pp. 1-52, 2009.
    • (2009) Morbidity and MortalityWeekly Report , vol.58 , pp. 1-52
    • Fiore, A.E.1    Shay, D.K.2    Broder, K.3
  • 4
    • 84887290174 scopus 로고    scopus 로고
    • New world bats harbor diverse influenza a viruses
    • S. Tong, X. Zhu, Y. Li et al., "New world bats harbor diverse influenza a viruses," PLoS Pathogens, vol. 9, Article IDe1003657, 2013.
    • (2013) PLoS Pathogens , vol.9
    • Tong, S.1    Zhu, X.2    Li, Y.3
  • 5
    • 0025359798 scopus 로고
    • Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983
    • P. A. Rota, T. R.Wallis, M. W. Harmon, J. S. Rota, A. P. Kendal, and K. Nerome, "Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983," Virology, vol. 175, no. 1, pp. 59-68, 1990.
    • (1990) Virology , vol.175 , Issue.1 , pp. 59-68
    • Rota, P.A.1    Wallis, T.R.2    Harmon, M.W.3    Rota, J.S.4    Kendal, A.P.5    Nerome, K.6
  • 6
    • 0032712272 scopus 로고    scopus 로고
    • Epidemiology and pathogenesis of influenza
    • M. C. Zambon, "Epidemiology and pathogenesis of influenza," Journal of Antimicrobial Chemotherapy, vol. 44, pp. 3-9, 1999.
    • (1999) Journal of Antimicrobial Chemotherapy , vol.44 , pp. 3-9
    • Zambon, M.C.1
  • 9
    • 10944240992 scopus 로고    scopus 로고
    • Influenza: Old and new threats
    • P. Palese, "Influenza: old and new threats," Nature Medicine, vol. 10, pp. S82-S87, 2004.
    • (2004) Nature Medicine , vol.10 , pp. S82-S87
    • Palese, P.1
  • 10
    • 0028803506 scopus 로고
    • European swine virus as a possible source for the next influenza pandemic?
    • S. Ludwig, L. Stitz, O. Planz, H. Van, W. M. Fitch, and C. Scholtissek, "European swine virus as a possible source for the next influenza pandemic?" Virology, vol. 212, no. 2, pp. 555-561, 1995.
    • (1995) Virology , vol.212 , Issue.2 , pp. 555-561
    • Ludwig, S.1    Stitz, L.2    Planz, O.3    Van, H.4    Fitch, W.M.5    Scholtissek, C.6
  • 11
    • 2542545140 scopus 로고    scopus 로고
    • Reemerging H5N1 influenza viruses in Hong Kong in 2002 are highly pathogenic to ducks
    • K. M. Sturm-Ramirez, T. Ellis, B. Bousfield et al., "Reemerging H5N1 influenza viruses in Hong Kong in 2002 are highly pathogenic to ducks," Journal of Virology, vol. 78, no. 9, pp. 4892-4901, 2004.
    • (2004) Journal of Virology , vol.78 , Issue.9 , pp. 4892-4901
    • Sturm-Ramirez, K.M.1    Ellis, T.2    Bousfield, B.3
  • 14
    • 0018072223 scopus 로고
    • A possible partial heterozygote of an influenza a virus
    • C. Scholtissek, W. Rohde, E. Harms, R. Rott, M. Orlich, and C. B. Boschek, "A possible partial heterozygote of an influenza a virus," Virology, vol. 89, no. 2, pp. 506-516, 1978.
    • (1978) Virology , vol.89 , Issue.2 , pp. 506-516
    • Scholtissek, C.1    Rohde, W.2    Harms, E.3    Rott, R.4    Orlich, M.5    Boschek, C.B.6
  • 15
    • 0024439330 scopus 로고
    • Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics
    • Y. Kawaoka, S. Krauss, and R. G. Webster, "Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics," Journal of Virology, vol. 63, no. 11, pp. 4603-4608, 1968.
    • (1968) Journal of Virology , vol.63 , Issue.11 , pp. 4603-4608
    • Kawaoka, Y.1    Krauss, S.2    Webster, R.G.3
  • 16
    • 0037295292 scopus 로고    scopus 로고
    • Influenzavirus-induced signaling cascades: Targets for antiviral therapy?
    • S. Ludwig, O. Planz, S. Pleschka, and T. Wolff, "Influenzavirus-induced signaling cascades: targets for antiviral therapy?" Trends in Molecular Medicine, vol. 9, no. 2, pp. 46-52, 2003.
    • (2003) Trends in Molecular Medicine , vol.9 , Issue.2 , pp. 46-52
    • Ludwig, S.1    Planz, O.2    Pleschka, S.3    Wolff, T.4
  • 17
    • 67449168158 scopus 로고    scopus 로고
    • Implications of the emergence of a novel H1 influenza virus
    • R. B. Belshe, "Implications of the emergence of a novel H1 influenza virus,"The New England Journal ofMedicine, vol. 360, no. 25, pp. 2667-2668, 2009.
    • (2009) The New England Journal OfMedicine , vol.360 , Issue.25 , pp. 2667-2668
    • Belshe, R.B.1
  • 18
    • 67650407532 scopus 로고    scopus 로고
    • Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans
    • R. J. Garten, C. T. Davis, C. A. Russell et al., "Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans," Science, vol. 325, no. 5937, pp. 197-201, 2009.
    • (2009) Science , vol.325 , Issue.5937 , pp. 197-201
    • Garten, R.J.1    Davis, C.T.2    Russell, C.A.3
  • 19
    • 14444284599 scopus 로고    scopus 로고
    • Characterization of an avian influenza A (H5N1) virus isolated froma child with a fatal respiratory illness
    • K. Subbarao, A. Klimov, J. Katz et al., "Characterization of an avian influenza A (H5N1) virus isolated froma child with a fatal respiratory illness," Science, vol. 279, no. 5349, pp. 393-396, 1998.
    • (1998) Science , vol.279 , Issue.5349 , pp. 393-396
    • Subbarao, K.1    Klimov, A.2    Katz, J.3
  • 20
    • 12944270582 scopus 로고    scopus 로고
    • Avian-to-human transmission of H9N2 subtype influenza A viruses: Relationship between H9N2 and H5N1 human isolates
    • Y. P. Lin, M. Shaw, V. Gregory et al., "Avian-to-human transmission of H9N2 subtype influenza A viruses: relationship between H9N2 and H5N1 human isolates," Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 17, pp. 9654-9658, 2000.
    • (2000) Proceedings of the National Academy of Sciences of the United States of America , vol.97 , Issue.17 , pp. 9654-9658
    • Lin, Y.P.1    Shaw, M.2    Gregory, V.3
  • 23
    • 31344450870 scopus 로고    scopus 로고
    • Making better influenza virus vaccines?
    • P. Palese, "Making better influenza virus vaccines?" Emerging Infectious Diseases, vol. 12, no. 1, pp. 61-65, 2006.
    • (2006) Emerging Infectious Diseases , vol.12 , Issue.1 , pp. 61-65
    • Palese, P.1
  • 24
    • 10744223896 scopus 로고    scopus 로고
    • Safety of cold-adapted live attenuated influenza vaccine in a large cohort of children and adolescents
    • R. Bergen, S. Black, H. Shinefield et al., "Safety of cold-adapted live attenuated influenza vaccine in a large cohort of children and adolescents," Pediatric InfectiousDisease Journal, vol. 23,no. 2, pp. 138-144, 2004.
    • (2004) Pediatric InfectiousDisease Journal , vol.23 , Issue.2 , pp. 138-144
    • Bergen, R.1    Black, S.2    Shinefield, H.3
  • 25
    • 4744344803 scopus 로고    scopus 로고
    • Safety, efficacy, and effectiveness of live, attenuated, cold-adapted influenza vaccine in an indicated population aged 5-49 years
    • R. B. Belshe, K. L. Nichol, S. B. Black et al., "Safety, efficacy, and effectiveness of live, attenuated, cold-adapted influenza vaccine in an indicated population aged 5-49 years," Clinical Infectious Diseases, vol. 39, no. 7, pp. 920-927, 2004.
    • (2004) Clinical Infectious Diseases , vol.39 , Issue.7 , pp. 920-927
    • Belshe, R.B.1    Nichol, K.L.2    Black, S.B.3
  • 28
    • 84861826001 scopus 로고    scopus 로고
    • The rationale for quadrivalent influenza vaccines
    • C. S. Ambrose and M. J. Levin, "The rationale for quadrivalent influenza vaccines," Human Vaccines & Immunotherapeutics, vol. 8, no. 1, pp. 81-88, 2012.
    • (2012) Human Vaccines & Immunotherapeutics , vol.8 , Issue.1 , pp. 81-88
    • Ambrose, C.S.1    Levin, M.J.2
  • 29
    • 29744438219 scopus 로고    scopus 로고
    • Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: An experiment of nature
    • S. L. Epstein, "Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: an experiment of nature,"TheJournal of Infectious Diseases, vol. 193, no. 1, pp. 49-53, 2006.
    • (2006) TheJournal of Infectious Diseases , vol.193 , Issue.1 , pp. 49-53
    • Epstein, S.L.1
  • 31
    • 0034083593 scopus 로고    scopus 로고
    • Correlates of immune protection induced by live, attenuated, coldadapted, trivalent, intranasal influenza virus vaccine
    • R. B. Belshe, W. C. Gruber, P. M. Mendelman et al., "Correlates of immune protection induced by live, attenuated, coldadapted, trivalent, intranasal influenza virus vaccine," Journal of Infectious Diseases, vol. 181, no. 3, pp. 1133-1137, 2000.
    • (2000) Journal of Infectious Diseases , vol.181 , Issue.3 , pp. 1133-1137
    • Belshe, R.B.1    Gruber, W.C.2    Mendelman, P.M.3
  • 32
    • 79751480796 scopus 로고    scopus 로고
    • The relative efficacy of trivalent live attenuated and inactivated influenza vaccines in children and adults
    • C. S. Ambrose, M. J. Levin, and R. B. Belshe, "The relative efficacy of trivalent live attenuated and inactivated influenza vaccines in children and adults," Influenza and other Respiratory Viruses, vol. 5, no. 2, pp. 67-75, 2011.
    • (2011) Influenza and Other Respiratory Viruses , vol.5 , Issue.2 , pp. 67-75
    • Ambrose, C.S.1    Levin, M.J.2    Belshe, R.B.3
  • 33
    • 0032516267 scopus 로고    scopus 로고
    • The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children
    • R. B. Belshe, P. M. Mendelman, J. Treanor et al., "The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children,"TheNew England Journal ofMedicine, vol. 338, no. 20, pp. 1405-1412, 1998.
    • (1998) TheNew England Journal OfMedicine , vol.338 , Issue.20 , pp. 1405-1412
    • Belshe, R.B.1    Mendelman, P.M.2    Treanor, J.3
  • 34
    • 0037146945 scopus 로고    scopus 로고
    • Selection of influenza vaccine strains and developing pandemic vaccines
    • J. M. Wood, "Selection of influenza vaccine strains and developing pandemic vaccines," Vaccine, vol. 20, supplement 5, pp. B40-B44, 2002.
    • (2002) Vaccine , vol.20 , pp. B40-B44
    • Wood, J.M.1
  • 35
    • 34548611066 scopus 로고    scopus 로고
    • Influenza vaccine: The challenge of antigenic drift
    • F. Carrat and A. Flahault, "Influenza vaccine: the challenge of antigenic drift," Vaccine, vol. 25, pp. 6852-6862, 2007.
    • (2007) Vaccine , vol.25 , pp. 6852-6862
    • Carrat, F.1    Flahault, A.2
  • 36
    • 33646830816 scopus 로고    scopus 로고
    • Epidermal DNA vaccine for influenza is immunogenic in humans
    • R. J. Drape, M. D. Macklin, L. J. Barr, S. Jones, J. R. Haynes, and H. J. Dean, "Epidermal DNA vaccine for influenza is immunogenic in humans," Vaccine, vol. 24, no. 21, pp. 4475-4481, 2006.
    • (2006) Vaccine , vol.24 , Issue.21 , pp. 4475-4481
    • Drape, R.J.1    Macklin, M.D.2    Barr, L.J.3    Jones, S.4    Haynes, J.R.5    Dean, H.J.6
  • 37
    • 0038037687 scopus 로고    scopus 로고
    • Pandemic influenza and the global vaccine supply
    • D. S. Fedson, "Pandemic influenza and the global vaccine supply," Clinical InfectiousDiseases, vol. 36,no. 12,pp. 1552-1561, 2003.
    • (2003) Clinical InfectiousDiseases , vol.36 , Issue.12 , pp. 1552-1561
    • Fedson, D.S.1
  • 38
    • 0034605496 scopus 로고    scopus 로고
    • Effectiveness and cost-benefit of influenza vaccination of healthy working adults: A randomized controlled trial
    • C. Buxton Bridges, W. W. Thompson, M. I. Meltzer et al., "Effectiveness and cost-benefit of influenza vaccination of healthy working adults: a randomized controlled trial," The Journal of the AmericanMedical Association, vol. 284, no. 13, pp. 1655-1663, 2000.
    • (2000) The Journal of the AmericanMedical Association , vol.284 , Issue.13 , pp. 1655-1663
    • Buxton Bridges, C.1    Thompson, W.W.2    Meltzer, M.I.3
  • 39
    • 19444368726 scopus 로고    scopus 로고
    • Universal influenza A vaccine: Optimization of M2-based constructs
    • M. de Filette, W. M. Jou, A. Birkett et al., "Universal influenza A vaccine: optimization of M2-based constructs," Virology, vol. 337, no. 1, pp. 149-161, 2005.
    • (2005) Virology , vol.337 , Issue.1 , pp. 149-161
    • De Filette, M.1    Jou, W.M.2    Birkett, A.3
  • 40
    • 0033618368 scopus 로고    scopus 로고
    • Surveillance and impact of influenza in Europe
    • M. Aymard, M. Valette, B. Lina, and D. Thouvenot, "Surveillance and impact of influenza in Europe," Vaccine, vol. 17, supplement 1, pp. S30-S41, 1999.
    • (1999) Vaccine , vol.17 , pp. S30-S41
    • Aymard, M.1    Valette, M.2    Lina, B.3    Thouvenot, D.4
  • 41
    • 0033618328 scopus 로고    scopus 로고
    • Surveillance and impact of influenza in the United States
    • A. Klimov, L. Simonsen, K. Fukuda, and N. Cox, "Surveillance and impact of influenza in the United States," Vaccine, vol. 17, supplement 1, pp. S42-S46, 1999.
    • (1999) Vaccine , vol.17 , pp. S42-S46
    • Klimov, A.1    Simonsen, L.2    Fukuda, K.3    Cox, N.4
  • 42
    • 0034072605 scopus 로고    scopus 로고
    • Mismatch between the 1997/1998 influenza vaccine and the major epidemic A(H3N2) virus strain as the cause of an inadequate vaccine-induced antibody response to this strain in the elderly
    • J.C. de Jong, W. E. P. Beyer, A. M. Palache, G. F. Rimmelzwaan, and A. D. Osterhaus, "Mismatch between the 1997/1998 influenza vaccine and the major epidemic A(H3N2) virus strain as the cause of an inadequate vaccine-induced antibody response to this strain in the elderly," Journal of Medical Virology, vol. 61, no. 1, pp. 94-99, 2000.
    • (2000) Journal of Medical Virology , vol.61 , Issue.1 , pp. 94-99
    • De Jong, J.C.1    Beyer, W.E.P.2    Palache, A.M.3    Rimmelzwaan, G.F.4    Osterhaus, A.D.5
  • 44
    • 0033783032 scopus 로고    scopus 로고
    • Receptor binding and membrane fusion in virus entry: The influenza hemagglutinin
    • J. J. Skehel and D. C. Wiley, "Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin," Annual Review of Biochemistry, vol. 69, pp. 531-569, 2000.
    • (2000) Annual Review of Biochemistry , vol.69 , pp. 531-569
    • Skehel, J.J.1    Wiley, D.C.2
  • 46
    • 0018862275 scopus 로고
    • Determination of the number of nonoverlapping antigenic areas on Hong Kong (H3N2) influenza virus hemagglutinin with monoclonal antibodies and the selection of variants with potential epidemiological significance
    • R. G. Webster and W. G. Laver, "Determination of the number of nonoverlapping antigenic areas on Hong Kong (H3N2) influenza virus hemagglutinin with monoclonal antibodies and the selection of variants with potential epidemiological significance," Virology, vol. 104, no. 1, pp. 139-148, 1980.
    • (1980) Virology , vol.104 , Issue.1 , pp. 139-148
    • Webster, R.G.1    Laver, W.G.2
  • 47
    • 0019827545 scopus 로고
    • Antigenic structure of influenza virus haemagglutinin defined by hybridoma antibodies
    • W. Gerhard, J. Yewdell, M. E. Frankel, and R. Webster, "Antigenic structure of influenza virus haemagglutinin defined by hybridoma antibodies," Nature, vol. 290, no. 5808, pp. 713-717, 1981.
    • (1981) Nature , vol.290 , Issue.5808 , pp. 713-717
    • Gerhard, W.1    Yewdell, J.2    Frankel, M.E.3    Webster, R.4
  • 48
    • 0023082135 scopus 로고
    • The structure and function of the hemagglutinin membrane glycoprotein of influenza virus
    • D. C. Wiley and J. J. Skehel, "The structure and function of the hemagglutinin membrane glycoprotein of influenza virus.," Annual Review of Biochemistry, vol. 56, pp. 365-394, 1987.
    • (1987) Annual Review of Biochemistry , vol.56 , pp. 365-394
    • Wiley, D.C.1    Skehel, J.J.2
  • 49
    • 0020416123 scopus 로고
    • The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype)
    • A. J. Caton, G. G. Brownlee, J. W. Yewdell, and W. Gerhard, "The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype)," Cell, vol. 31, no. 2, pp. 417-427, 1982.
    • (1982) Cell , vol.31 , Issue.2 , pp. 417-427
    • Caton, A.J.1    Brownlee, G.G.2    Yewdell, J.W.3    Gerhard, W.4
  • 50
    • 0019432165 scopus 로고
    • Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation
    • D. C. Wiley, I. A. Wilson, and J. J. Skehel, "Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation," Nature, vol. 289, pp. 373-378, 1981.
    • (1981) Nature , vol.289 , pp. 373-378
    • Wiley, D.C.1    Wilson, I.A.2    Skehel, J.J.3
  • 51
    • 0029558245 scopus 로고
    • A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pHinduced conformation
    • J. Chen, S. A. Wharton, W. Weissenhorn et al., "A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pHinduced conformation," Proceedings of the National Academy of Sciences of the United States of America, vol. 92, no. 26, pp. 12205-12209, 1995.
    • (1995) Proceedings of the National Academy of Sciences of the United States of America , vol.92 , Issue.26 , pp. 12205-12209
    • Chen, J.1    Wharton, S.A.2    Weissenhorn, W.3
  • 52
    • 0016590407 scopus 로고
    • Enhancement of the infectivity of influenca A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide
    • S. G. Lazarowitz and P. W. Choppin, "Enhancement of the infectivity of influenca A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide," Virology, vol. 68, no. 2, pp. 440-454, 1975.
    • (1975) Virology , vol.68 , Issue.2 , pp. 440-454
    • Lazarowitz, S.G.1    Choppin, P.W.2
  • 53
    • 0028331821 scopus 로고
    • Reverse genetics provides direct evidence for a correlation of hemagglutinin cleavability and virulence of an avian influenza A virus
    • T. Horimoto and Y. Kawaoka, "Reverse genetics provides direct evidence for a correlation of hemagglutinin cleavability and virulence of an avian influenza A virus," Journal of Virology, vol. 68, no. 5, pp. 3120-3128, 1994.
    • (1994) Journal of Virology , vol.68 , Issue.5 , pp. 3120-3128
    • Horimoto, T.1    Kawaoka, Y.2
  • 54
    • 0033602713 scopus 로고    scopus 로고
    • Role of hemagglutinin cleavage for the pathogenicity of influenza virus
    • D. A. Steinhauer, "Role of hemagglutinin cleavage for the pathogenicity of influenza virus," Virology, vol. 258, no. 1, pp. 1-20, 1999.
    • (1999) Virology , vol.258 , Issue.1 , pp. 1-20
    • Steinhauer, D.A.1
  • 55
    • 77956639165 scopus 로고    scopus 로고
    • Novel insights into proteolytic cleavage of influenza virus hemagglutinin
    • S. Bertram, I. Glowacka, I. Steffen, A. Kühl, and S. Pöhlmann, "Novel insights into proteolytic cleavage of influenza virus hemagglutinin," Reviews in Medical Virology, vol. 20, no. 5, pp. 298-310, 2010.
    • (2010) Reviews in Medical Virology , vol.20 , Issue.5 , pp. 298-310
    • Bertram, S.1    Glowacka, I.2    Steffen, I.3    Kühl, A.4    Pöhlmann, S.5
  • 56
    • 0022619527 scopus 로고
    • Studies on the mechanism of membrane fusion: Site-specific mutagenesis of the hemagglutinin of influenza virus
    • M.-J. Gething, R. W. Doms, D. York, and J. White, "Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virus," The Journal of Cell Biology, vol. 102, no. 1, pp. 11-23, 1986.
    • (1986) The Journal of Cell Biology , vol.102 , Issue.1 , pp. 11-23
    • Gething, M.-J.1    Doms, R.W.2    York, D.3    White, J.4
  • 57
    • 78649989474 scopus 로고    scopus 로고
    • Induction of unnatural immunity: Prospects for a broadly protective universal influenza vaccine
    • G. J. Nabel and A. S. Fauci, "Induction of unnatural immunity: prospects for a broadly protective universal influenza vaccine," Nature Medicine, vol. 16, no. 12, pp. 1389-1391, 2010.
    • (2010) Nature Medicine , vol.16 , Issue.12 , pp. 1389-1391
    • Nabel, G.J.1    Fauci, A.S.2
  • 58
    • 79952140653 scopus 로고    scopus 로고
    • Influenza virus vaccine based on the conserved hemagglutinin stalk domain
    • J. Steel, A. C. Lowen, T. T. Wang, M. Yondola, and Q. Gao, "Influenza virus vaccine based on the conserved hemagglutinin stalk domain," mBio, vol. 1, no. 1,Article ID e00018-10, 2010.
    • (2010) MBio , vol.1 , Issue.1
    • Steel, J.1    Lowen, A.C.2    Wang, T.T.3    Yondola, M.4    Gao, Q.5
  • 59
    • 0027471177 scopus 로고
    • A common neutralizing epitope conserved between the hemagglutinins of influenza A virusH1 and H2 strains
    • Y. Okuno, Y. Isegawa, F. Sasao, and S. Ueda, "A common neutralizing epitope conserved between the hemagglutinins of influenza A virusH1 and H2 strains," Journal of Virology, vol. 67, no. 5, pp. 2552-2558, 1993.
    • (1993) Journal of Virology , vol.67 , Issue.5 , pp. 2552-2558
    • Okuno, Y.1    Isegawa, Y.2    Sasao, F.3    Ueda, S.4
  • 60
    • 0032822080 scopus 로고    scopus 로고
    • An epitope shared by the hemagglutinins of H1, H2, H5, and H6 subtypes of influenza A virus
    • Y. A. Smirnov, A. S. Lipatov, A. K. Gitelman et al., "An epitope shared by the hemagglutinins of H1, H2, H5, and H6 subtypes of influenza A virus," Acta Virologica, vol. 43,no. 4, pp. 237-244, 1999.
    • (1999) Acta Virologica , vol.43 , Issue.4 , pp. 237-244
    • Smirnov, Y.A.1    Lipatov, A.S.2    Gitelman, A.K.3
  • 61
    • 0033857323 scopus 로고    scopus 로고
    • Prevention and treatment of bronchopneumonia in mice caused by mouse-adapted variant of avian H5N2 influenza A virus using monoclonal antibody against conserved epitope in the HA stem region
    • Y. A. Smirnov, A. S. Lipatov, A. K. Gitelman, E. C. J. Claas, and A. D. M. E. Osterhaus, "Prevention and treatment of bronchopneumonia in mice caused by mouse-adapted variant of avian H5N2 influenza A virus using monoclonal antibody against conserved epitope in the HA stem region," Archives of Virology, vol. 145, no. 8, pp. 1733-1741, 2000.
    • (2000) Archives of Virology , vol.145 , Issue.8 , pp. 1733-1741
    • Smirnov, Y.A.1    Lipatov, A.S.2    Gitelman, A.K.3    Claas, E.C.J.4    Osterhaus, A.D.M.E.5
  • 62
    • 78650231989 scopus 로고    scopus 로고
    • A crossreactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus infection
    • S. Sakabe, K. Iwatsuki-Horimoto, T. Horimoto et al., "A crossreactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus infection," Antiviral Research, vol. 88, no. 3, pp. 249-255, 2010.
    • (2010) Antiviral Research , vol.88 , Issue.3 , pp. 249-255
    • Sakabe, S.1    Iwatsuki-Horimoto, K.2    Horimoto, T.3
  • 63
    • 84877920759 scopus 로고    scopus 로고
    • Structure of a classical broadly neutralizing stem antibody in complex with a pandemic H2 influenza virus hemagglutinin
    • C. Dreyfus, D. C. Ekiert, and I. A. Wilson, "Structure of a classical broadly neutralizing stem antibody in complex with a pandemic H2 influenza virus hemagglutinin," Journal of Virology, vol. 87, no. 12, pp. 7149-7154, 2013.
    • (2013) Journal of Virology , vol.87 , Issue.12 , pp. 7149-7154
    • Dreyfus, C.1    Ekiert, D.C.2    Wilson, I.A.3
  • 64
    • 62049083943 scopus 로고    scopus 로고
    • Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
    • J. Sui, W. C. Hwang, S. Perez et al., "Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses," Nature Structural&Molecular Biology, vol. 16, no. 3, pp. 265-273, 2009.
    • (2009) Nature Structural&Molecular Biology , vol.16 , Issue.3 , pp. 265-273
    • Sui, J.1    Hwang, W.C.2    Perez, S.3
  • 65
    • 58049198443 scopus 로고    scopus 로고
    • Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells
    • M. Throsby, E. van den Brink, M. Jongeneelen et al., "Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells," PLoS ONE, vol. 3, no. 12, Article IDe3942, 2008.
    • (2008) PLoS ONE , vol.3 , Issue.12
    • Throsby, M.1    Brink Den E.Van2    Jongeneelen, M.3
  • 66
    • 64849114224 scopus 로고    scopus 로고
    • Antibody recognition of a highly conserved influenza virus epitope
    • D. C. Ekiert, G. Bhabha, M.-A. Elsliger et al., "Antibody recognition of a highly conserved influenza virus epitope," Science, vol. 324, no. 5924, pp. 246-251, 2009.
    • (2009) Science , vol.324 , Issue.5924 , pp. 246-251
    • Ekiert, D.C.1    Bhabha, G.2    Elsliger, M.-A.3
  • 67
    • 84866953140 scopus 로고    scopus 로고
    • Cross-neutralization of influenza a viruses mediated by a single antibody loop
    • D. C. Ekiert, A. K. Kashyap, J. Steel et al., "Cross-neutralization of influenza a viruses mediated by a single antibody loop," Nature, vol. 489, no. 7417, pp. 526-532, 2012.
    • (2012) Nature , vol.489 , Issue.7417 , pp. 526-532
    • Ekiert, D.C.1    Kashyap, A.K.2    Steel, J.3
  • 68
    • 77951876927 scopus 로고    scopus 로고
    • Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine
    • D. Corti, A. L. Suguitan Jr., D. Pinna et al., "Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine," The Journal of Clinical Investigation, vol. 120, no. 5, pp. 1663-1673, 2010.
    • (2010) The Journal of Clinical Investigation , vol.120 , Issue.5 , pp. 1663-1673
    • Corti, D.1    Suguitan, A.L.2    Pinna, D.3
  • 69
    • 74249110309 scopus 로고    scopus 로고
    • Molecular cloning of the first human monoclonal antibodies neutralizing with high potency swine-origin influenza A pandemic virus (S-OIV)
    • R. Burioni, F. Canducci,N.Mancini et al., "Molecular cloning of the first human monoclonal antibodies neutralizing with high potency swine-origin influenza A pandemic virus (S-OIV)," New Microbiologica, vol. 32, no. 4, pp. 319-324, 2009.
    • (2009) New Microbiologica , vol.32 , Issue.4 , pp. 319-324
    • Burioni, R.1    Canducci, F.2    Mancini, N.3
  • 70
    • 77049088439 scopus 로고    scopus 로고
    • Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV)
    • R. Burioni, F. Canducci, N. Mancini et al., "Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV)," Virology, vol. 399, no. 1, pp. 144-152, 2010.
    • (2010) Virology , vol.399 , Issue.1 , pp. 144-152
    • Burioni, R.1    Canducci, F.2    Mancini, N.3
  • 71
    • 84859364851 scopus 로고    scopus 로고
    • A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses
    • D. de Marco, N. Clementi, N. Mancini et al., "A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses," PLoS ONE, vol. 7, no. 4, Article ID e34415, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.4
    • De Marco, D.1    Clementi, N.2    Mancini, N.3
  • 72
    • 78651488739 scopus 로고    scopus 로고
    • Broadly crossreactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
    • J.Wrammert, D. Koutsonanos, G. M. Li et al., "Broadly crossreactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection," Journal of Experimental Medicine, vol. 208, no. 1, pp. 181-193, 2011.
    • (2011) Journal of Experimental Medicine , vol.208 , Issue.1 , pp. 181-193
    • Wrammert, J.1    Koutsonanos, D.2    Li, G.M.3
  • 73
    • 43149109969 scopus 로고    scopus 로고
    • Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies
    • A. K.Kashyap, J. Steel, A. F. Oner et al., "Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies," Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 16, pp. 5986-5991, 2008.
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.16 , pp. 5986-5991
    • Kashyap, A.K.1    Steel, J.2    Oner, A.F.3
  • 74
    • 77957678820 scopus 로고    scopus 로고
    • Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivor-based libraries
    • A. K. Kashyap, J. Steel, A. Rubrum et al., "Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivor-based libraries," PLoS Pathogens, vol. 6, no. 7, Article ID e1000990, 7 pages, 2010.
    • (2010) PLoS Pathogens , vol.6 , Issue.7
    • Kashyap, A.K.1    Steel, J.2    Rubrum, A.3
  • 75
    • 84861872090 scopus 로고    scopus 로고
    • Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells
    • G.-M. Li, C. Chiu, J. Wrammert et al., "Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells," Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 23, pp. 9047-9052, 2012.
    • (2012) Proceedings of the National Academy of Sciences of the United States of America , vol.109 , Issue.23 , pp. 9047-9052
    • Li, G.-M.1    Chiu, C.2    Wrammert, J.3
  • 76
    • 80051635697 scopus 로고    scopus 로고
    • A highly conserved neutralizing epitope on group 2 influenza A viruses
    • D. C. Ekiert, R. H. E. Friesen, G. Bhabha et al., "A highly conserved neutralizing epitope on group 2 influenza A viruses," Science, vol. 333, no. 6044, pp. 843-850, 2011.
    • (2011) Science , vol.333 , Issue.6044 , pp. 843-850
    • Ekiert, D.C.1    Friesen, R.H.E.2    Bhabha, G.3
  • 78
    • 80051670323 scopus 로고    scopus 로고
    • A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
    • D. Corti, J. Voss, S. J. Gamblin et al., "A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins," Science, vol. 333, no. 6044, pp. 850-856, 2011.
    • (2011) Science , vol.333 , Issue.6044 , pp. 850-856
    • Corti, D.1    Voss, J.2    Gamblin, S.J.3
  • 79
    • 82955194795 scopus 로고    scopus 로고
    • A human monoclonal antibody with neutralizing activity against highly divergent influenza subtypes
    • N. Clementi, D. de Marco, N. Mancini et al., "A human monoclonal antibody with neutralizing activity against highly divergent influenza subtypes," PLoS ONE, vol. 6, no. 12, Article ID e28001, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.12
    • Clementi, N.1    De Marco, D.2    Mancini, N.3
  • 80
    • 84880427552 scopus 로고    scopus 로고
    • An in vivo humanplasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies
    • G. Nakamura, N. Chai, S. Park et al., "An in vivo humanplasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies," Cell Host andMicrobe, vol. 14, no. 1, pp. 93-103, 2013.
    • (2013) Cell Host AndMicrobe , vol.14 , Issue.1 , pp. 93-103
    • Nakamura, G.1    Chai, N.2    Park, S.3
  • 81
    • 84866122029 scopus 로고    scopus 로고
    • Highly conserved protective epitopes on influenza B viruses
    • C. Dreyfus, N. S. Laursen, T. Kwaks et al., "Highly conserved protective epitopes on influenza B viruses," Science, vol. 337, no. 6100, pp. 1343-1348, 2012.
    • (2012) Science , vol.337 , Issue.6100 , pp. 1343-1348
    • Dreyfus, C.1    Laursen, N.S.2    Kwaks, T.3
  • 82
    • 52949088297 scopus 로고    scopus 로고
    • Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors
    • X. Yu, T. Tsibane, P. A. McGraw et al., "Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors," Nature, vol. 455, no. 7212, pp. 532-536, 2008.
    • (2008) Nature , vol.455 , Issue.7212 , pp. 532-536
    • Yu, X.1    Tsibane, T.2    McGraw, P.A.3
  • 83
    • 84872026547 scopus 로고    scopus 로고
    • Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity inH1N1 viruses
    • T. Tsibane, D. C. Ekiert, J. C. Krause et al., "Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity inH1N1 viruses," PLoS Pathogens, vol. 8, no. 12, Article ID e1003067, 2012.
    • (2012) PLoS Pathogens , vol.8 , Issue.12
    • Tsibane, T.1    Ekiert, D.C.2    Krause, J.C.3
  • 84
    • 79955113580 scopus 로고    scopus 로고
    • An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody
    • J. C. Krause, D. C. Ekiert, T. M. Tumpey, P. B. Smith, I. A. Wilson, and J. E. Crowe, "An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody," mBio, vol. 2, no. 1, 2011.
    • (2011) MBio , vol.2 , Issue.1
    • Krause, J.C.1    Ekiert, D.C.2    Tumpey, T.M.3    Smith, P.B.4    Wilson, I.A.5    Crowe, J.E.6
  • 85
    • 80053474133 scopus 로고    scopus 로고
    • A broadly neutralizing humanmonoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin
    • J. C. Krause, T. Tsibane, T. M. Tumpey, C. J. Huffman, C. F. Basler, and J. E. Crowe Jr., "A broadly neutralizing humanmonoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin," Journal of Virology, vol. 85, no. 20, pp. 10905-10908, 2011.
    • (2011) Journal of Virology , vol.85 , Issue.20 , pp. 10905-10908
    • Krause, J.C.1    Tsibane, T.2    Tumpey, T.M.3    Huffman, C.J.4    Basler, C.F.5    Crowe, J.E.6
  • 86
    • 77951165843 scopus 로고    scopus 로고
    • Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus
    • R.Xu, D. C. Ekiert, J.C.Krause, R. Hai, J. E. Crowe Jr., and I. A. Wilson, "Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus," Science, vol. 328, no. 5976, pp. 357-360, 2010.
    • (2010) Science , vol.328 , Issue.5976 , pp. 357-360
    • Xu, R.1    Ekiert, D.C.2    Krause, J.C.3    Hai, R.4    Crowe, J.E.5    Wilson, I.A.6
  • 87
    • 84886314094 scopus 로고    scopus 로고
    • Antibody recognition of the pandemic H1N1 influenza virus hemagglutinin receptor binding site
    • M. Hong, P. S. Lee, R. M. B. Hoffman et al., "Antibody recognition of the pandemic H1N1 influenza virus hemagglutinin receptor binding site," Journal of Virology, vol. 87, no. 22, pp. 12471-12480, 2013.
    • (2013) Journal of Virology , vol.87 , Issue.22 , pp. 12471-12480
    • Hong, M.1    Lee, P.S.2    Hoffman, R.M.B.3
  • 88
  • 89
    • 84871994029 scopus 로고    scopus 로고
    • Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody
    • A. G. Schmidt, H. Xu, A. R. Khan et al., "Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody," Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 1, pp. 264-269, 2013.
    • (2013) Proceedings of the National Academy of Sciences of the United States of America , vol.110 , Issue.1 , pp. 264-269
    • Schmidt, A.G.1    Xu, H.2    Khan, A.R.3
  • 90
    • 84863568230 scopus 로고    scopus 로고
    • Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses
    • J. C. Krause, T. Tsibane, T. M. Tumpey et al., "Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses," Journal of Virology, vol. 86, no. 11, pp. 6334-6340, 2012.
    • (2012) Journal of Virology , vol.86 , Issue.11 , pp. 6334-6340
    • Krause, J.C.1    Tsibane, T.2    Tumpey, T.M.3
  • 91
    • 84875186505 scopus 로고    scopus 로고
    • A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin
    • R. Xu, J. C. Krause, R. Mcbride, J. C. Paulson, J. E. Crowe Jr., and I. A. Wilson, "A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin," Nature Structural and Molecular Biology, vol. 20, no. 3, pp. 363-370, 2013.
    • (2013) Nature Structural and Molecular Biology , vol.20 , Issue.3 , pp. 363-370
    • Xu, R.1    Krause, J.C.2    McBride, R.3    Paulson, J.C.4    Crowe, J.E.5    Wilson, I.A.6
  • 92
    • 51449103253 scopus 로고    scopus 로고
    • Identification of a human monoclonal Fab with neutralizing activity against H3N2 influenza A strain from a newly constructed human Fab library
    • T. Shibuya, T. Yamashiro, Y. Masaike, M. Ohuchi, G.-I. Uechi, and A. Nishizono, "Identification of a human monoclonal Fab with neutralizing activity against H3N2 influenza A strain from a newly constructed human Fab library," Microbiology & Immunology, vol. 52, no. 3, pp. 162-170, 2008.
    • (2008) Microbiology & Immunology , vol.52 , Issue.3 , pp. 162-170
    • Shibuya, T.1    Yamashiro, T.2    Masaike, Y.3    Ohuchi, M.4    Uechi, G.-I.5    Nishizono, A.6
  • 93
    • 80055111172 scopus 로고    scopus 로고
    • Naturally occurring antibodies in humans can neutralize a variety of influenza virus strains, including H3, H1, H2, and H5
    • N. Ohshima, Y. Iba, R. Kubota-Koketsu, Y. Asano, Y. Okuno, and Y. Kurosawa, "Naturally occurring antibodies in humans can neutralize a variety of influenza virus strains, including H3, H1, H2, and H5," Journal of Virology, vol. 85, no. 21, pp. 11048-11057, 2011.
    • (2011) Journal of Virology , vol.85 , Issue.21 , pp. 11048-11057
    • Ohshima, N.1    Iba, Y.2    Kubota-Koketsu, R.3    Asano, Y.4    Okuno, Y.5    Kurosawa, Y.6
  • 94
    • 84901981487 scopus 로고    scopus 로고
    • Conserved neutralizing epitope at globular head of hemagglutinin in H3N2 influenza viruses
    • Y. Iba, Y. Fujii, N. Ohshima et al., "Conserved neutralizing epitope at globular head of hemagglutinin in H3N2 influenza viruses," Journal of Virology, vol. 88, no. 13, pp. 7130-7144, 2014.
    • (2014) Journal of Virology , vol.88 , Issue.13 , pp. 7130-7144
    • Iba, Y.1    Fujii, Y.2    Ohshima, N.3
  • 95
    • 65549170411 scopus 로고    scopus 로고
    • Generation, characterization and epitope mapping of two neutralizing and protective human recombinant antibodies against influenza A H5N1 viruses
    • L. Sun, X. Lu, C. Li et al., "Generation, characterization and epitope mapping of two neutralizing and protective human recombinant antibodies against influenza A H5N1 viruses," PLoS ONE, vol. 4, no. 5,Article ID e5476, 2009.
    • (2009) PLoS ONE , vol.4 , Issue.5
    • Sun, L.1    Lu, X.2    Li, C.3
  • 96
    • 34249669303 scopus 로고    scopus 로고
    • Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza
    • C. P. Simmons, N. L. Bernasconi, A. L. Suguitan Jr. et al., "Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza," PLoS Medicine, vol. 4, no. 5, article e178, 2007.
    • (2007) PLoS Medicine , vol.4 , Issue.5
    • Simmons, C.P.1    Bernasconi, N.L.2    Suguitan, A.L.3
  • 97
    • 66149149791 scopus 로고    scopus 로고
    • Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets
    • S. Khurana, A. L. Suguitan Jr., Y. Rivera et al., "Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets," PLoS Medicine, vol. 6, no. 4, Article ID e1000049, 2009.
    • (2009) PLoS Medicine , vol.6 , Issue.4
    • Khurana, S.1    Suguitan, A.L.2    Rivera, Y.3
  • 98
    • 63449125762 scopus 로고    scopus 로고
    • Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses
    • R. Yoshida, M. Igarashi, H. Ozaki et al., "Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses," PLoS Pathogens, vol. 5, no. 3,Article ID e1000350, 2009.
    • (2009) PLoS Pathogens , vol.5 , Issue.3
    • Yoshida, R.1    Igarashi, M.2    Ozaki, H.3
  • 99
    • 84867641531 scopus 로고    scopus 로고
    • Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity
    • P. S. Lee, R. Yoshida, D. C. Ekiert et al., "Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity," Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 42, pp. 17040-17045, 2012.
    • (2012) Proceedings of the National Academy of Sciences of the United States of America , vol.109 , Issue.42 , pp. 17040-17045
    • Lee, P.S.1    Yoshida, R.2    Ekiert, D.C.3
  • 100
    • 84893797938 scopus 로고    scopus 로고
    • Broadly neutralizing hemagglutinin stalk-specific antibodies require FcR interactions for protection against influenza virus in vivo
    • D. J. DiLillo, G. S. Tan, P. Palese, and J. V. Ravetch, "Broadly neutralizing hemagglutinin stalk-specific antibodies require FcR interactions for protection against influenza virus in vivo," Nature Medicine, vol. 20, pp. 143-151, 2014.
    • (2014) Nature Medicine , vol.20 , pp. 143-151
    • Dilillo, D.J.1    Tan, G.S.2    Palese, P.3    Ravetch, J.V.4
  • 101
    • 84863115945 scopus 로고    scopus 로고
    • Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses
    • N. Pica, R. Hai, F. Krammer et al., "Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses," Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 7, pp. 2573-2578, 2012.
    • (2012) Proceedings of the National Academy of Sciences of the United States of America , vol.109 , Issue.7 , pp. 2573-2578
    • Pica, N.1    Hai, R.2    Krammer, F.3
  • 102
    • 84864824020 scopus 로고    scopus 로고
    • Pandemic H1N1 influenza infection and vaccination in humans induces crossprotective antibodies that target the hemagglutinin stem
    • C. A.Thomson, Y.Wang, L. M. Jackson et al., "Pandemic H1N1 influenza infection and vaccination in humans induces crossprotective antibodies that target the hemagglutinin stem," Frontiers in Immunology, vol. 3, article 87, 2012.
    • (2012) Frontiers in Immunology , vol.3
    • Thomson, C.A.1    Wang, Y.2    Jackson, L.M.3
  • 103
    • 84872924387 scopus 로고    scopus 로고
    • 1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans
    • M. S. Miller, T. Tsibane, F. Krammer et al., "1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans," Journal of Infectious Diseases, vol. 207, no. 1, pp. 98-105, 2013.
    • (2013) Journal of Infectious Diseases , vol.207 , Issue.1 , pp. 98-105
    • Miller, M.S.1    Tsibane, T.2    Krammer, F.3
  • 104
    • 84871805315 scopus 로고    scopus 로고
    • Heterovariant cross-reactive B-cell responses induced by the 2009 pandemic influenza virus A subtype H1N1 vaccine
    • X.-S. He, S. Sasaki, J. Baer et al., "Heterovariant cross-reactive B-cell responses induced by the 2009 pandemic influenza virus A subtype H1N1 vaccine," The Journal of Infectious Diseases, vol. 207, no. 2, pp. 288-296, 2013.
    • (2013) The Journal of Infectious Diseases , vol.207 , Issue.2 , pp. 288-296
    • He, X.-S.1    Sasaki, S.2    Baer, J.3
  • 105
    • 78649759121 scopus 로고    scopus 로고
    • Intranasal immunization with influenza VLPs incorporating membrane-anchored flagellin induces strong heterosubtypic protection
    • B.-Z. Wang, R. Xu, F.-S. Quan, S.-M. Kang, L. Wang, and R. W. Compans, "Intranasal immunization with influenza VLPs incorporating membrane-anchored flagellin induces strong heterosubtypic protection," PLoS ONE, vol. 5, no. 11, Article ID e13972, 2010.
    • (2010) PLoS ONE , vol.5 , Issue.11
    • Wang, B.-Z.1    Xu, R.2    Quan, F.-S.3    Kang, S.-M.4    Wang, L.5    Compans, R.W.6
  • 106
    • 84906089277 scopus 로고    scopus 로고
    • Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity
    • J. V. Pérez-Girón, A. Belicha-Villanueva, E. Hassan et al., "Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity," The Journal of Immunology, vol. 193, no. 3, pp. 1324-1332, 2014.
    • (2014) The Journal of Immunology , vol.193 , Issue.3 , pp. 1324-1332
    • Pérez-Girón, J.V.1    Belicha-Villanueva, A.2    Hassan, E.3
  • 107
    • 84904397430 scopus 로고    scopus 로고
    • AS04-adjuvanted viruslike particles containing multiple M2 extracellular domains of influenza virus confer improved protection
    • Y.-N. Lee, M.-C. Kim, Y.-T. Lee et al., "AS04-adjuvanted viruslike particles containing multiple M2 extracellular domains of influenza virus confer improved protection," Vaccine, vol. 32, no. 35, pp. 4578-4585, 2014.
    • (2014) Vaccine , vol.32 , Issue.35 , pp. 4578-4585
    • Lee, Y.-N.1    Kim, M.-C.2    Lee, Y.-T.3
  • 108
    • 84877067760 scopus 로고    scopus 로고
    • Critical role of TLR7 signaling in the priming of cross-protective cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine
    • N. Budimir, A. de Haan, T. Meijerhof et al., "Critical role of TLR7 signaling in the priming of cross-protective cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine," PLoS ONE, vol. 8, no. 5,Article ID e63163, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.5
    • Budimir, N.1    De Haan, A.2    Meijerhof, T.3
  • 109
    • 84890554900 scopus 로고    scopus 로고
    • Adjuvants and immunization strategies to induce influenza virus hemagglutinin stalk antibodies
    • P. H. Goff, D. Eggink, C.W. Seibert et al., "Adjuvants and immunization strategies to induce influenza virus hemagglutinin stalk antibodies," PLoS ONE, vol. 8, no. 11, Article ID e79194, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.11
    • Goff, P.H.1    Eggink, D.2    Seibert, C.W.3
  • 110
    • 84907973731 scopus 로고    scopus 로고
    • Enhanced and persistent antibody response against homologous and heterologous strains elicited by a MF59-adjuvanted influenza vaccine in infants and young children
    • T. Nolan, L. Bravo, A. Ceballos et al., "Enhanced and persistent antibody response against homologous and heterologous strains elicited by a MF59-adjuvanted influenza vaccine in infants and young children," Vaccine, vol. 32, pp. 6146-6156, 2014.
    • (2014) Vaccine , vol.32 , pp. 6146-6156
    • Nolan, T.1    Bravo, L.2    Ceballos, A.3
  • 111
    • 84870382373 scopus 로고    scopus 로고
    • Heterosubtypic protection against influenza A induced by adenylate cyclase toxoids delivering conserved HA2 subunit of hemagglutinin
    • Z. Staneková, I. Adkins, M. Kosová, J. Janulíková, P. Sebo, and E. Varecková, "Heterosubtypic protection against influenza A induced by adenylate cyclase toxoids delivering conserved HA2 subunit of hemagglutinin," Antiviral Research, vol. 97, no. 1, pp. 24-35, 2013.
    • (2013) Antiviral Research , vol.97 , Issue.1 , pp. 24-35
    • Staneková, Z.1    Adkins, I.2    Kosová, M.3    Janulíková, J.4    Sebo, P.5    Varecková, E.6
  • 112
    • 84921462503 scopus 로고    scopus 로고
    • Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes
    • X. Fan, A. M. Hashem, Z. Chen et al., "Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes," Mucosal Immunology, vol. 8, pp. 211-220, 2015.
    • (2015) Mucosal Immunology , vol.8 , pp. 211-220
    • Fan, X.1    Hashem, A.M.2    Chen, Z.3
  • 113
    • 84867608670 scopus 로고    scopus 로고
    • Novel viral vectored vaccines for the prevention of influenza
    • T. Lambe, "Novel viral vectored vaccines for the prevention of influenza,"MolecularMedicine, vol. 18,no. 8, pp. 1153-1160, 2012.
    • (2012) MolecularMedicine , vol.18 , Issue.8 , pp. 1153-1160
    • Lambe, T.1
  • 114
    • 79953139384 scopus 로고    scopus 로고
    • Protection against divergent influenza H1N1 virus by a centralized influenza hemagglutinin
    • E.A.Weaver, A.M. Rubrum,R. J.Webby, andM. A. Barry, "Protection against divergent influenza H1N1 virus by a centralized influenza hemagglutinin," PLoS ONE, vol. 6, no. 3, Article ID e18314, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.3
    • Weaver, E.A.1    Rubrum, A.M.2    Webby, R.J.3    Barry, M.A.4
  • 115
    • 84899955795 scopus 로고    scopus 로고
    • Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine
    • J. Yan, D. O. Villarreal, T. Racine et al., "Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine," Vaccine, vol. 32, no. 24, pp. 2833-2842, 2014.
    • (2014) Vaccine , vol.32 , Issue.24 , pp. 2833-2842
    • Yan, J.1    Villarreal, D.O.2    Racine, T.3
  • 117
    • 84869075297 scopus 로고    scopus 로고
    • A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin
    • A. Schneemann, J. A. Speir, G. S. Tan et al., "A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin," Journal of Virology, vol. 86, no. 21, pp. 11686-11697, 2012.
    • (2012) Journal of Virology , vol.86 , Issue.21 , pp. 11686-11697
    • Schneemann, A.1    Speir, J.A.2    Tan, G.S.3
  • 118
    • 84896316266 scopus 로고    scopus 로고
    • Intranasal vaccination with a replication-deficient influenza virus induces heterosubtypic neutralising mucosal IgA antibodies in humans
    • A. Morokutti, T. Muster, and B. Ferko, "Intranasal vaccination with a replication-deficient influenza virus induces heterosubtypic neutralising mucosal IgA antibodies in humans," Vaccine, vol. 32, no. 17, pp. 1897-1900, 2014.
    • (2014) Vaccine , vol.32 , Issue.17 , pp. 1897-1900
    • Morokutti, A.1    Muster, T.2    Ferko, B.3
  • 119
    • 84355161915 scopus 로고    scopus 로고
    • Oral vaccination with inactivated influenza vaccine induces cross-protective immunity
    • F.-S. Quan, R.W. Compans, and S.-M. Kang, "Oral vaccination with inactivated influenza vaccine induces cross-protective immunity," Vaccine, vol. 30, no. 2, pp. 180-188, 2012.
    • (2012) Vaccine , vol.30 , Issue.2 , pp. 180-188
    • Quan, F.-S.1    Compans, R.W.2    Kang, S.-M.3
  • 120
    • 77956119219 scopus 로고    scopus 로고
    • Induction of broadly neutralizingH1N1 influenza antibodies by vaccination
    • C. J. Wei, J. C. Boyington, P. M. McTamney et al., "Induction of broadly neutralizingH1N1 influenza antibodies by vaccination," Science, vol. 329, no. 5995, pp. 1060-1064, 2010.
    • (2010) Science , vol.329 , Issue.5995 , pp. 1060-1064
    • Wei, C.J.1    Boyington, J.C.2    McTamney, P.M.3
  • 121
    • 78649953803 scopus 로고    scopus 로고
    • Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes
    • T. T. Wang, G. S. Tan, R. Hai et al., "Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes," Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 44, pp. 18979-18984, 2010.
    • (2010) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , Issue.44 , pp. 18979-18984
    • Wang, T.T.1    Tan, G.S.2    Hai, R.3
  • 122
    • 55049102432 scopus 로고    scopus 로고
    • Universal antibodies and their applications to the quantitative determination of virtually all subtypes of the influenza A viral hemagglutinins
    • S. Chun, C. Li, G. van Domselaar et al., "Universal antibodies and their applications to the quantitative determination of virtually all subtypes of the influenza A viral hemagglutinins," Vaccine, vol. 26, no. 48, pp. 6068-6076, 2008.
    • (2008) Vaccine , vol.26 , Issue.48 , pp. 6068-6076
    • Chun, S.1    Li, C.2    Van Domselaar, G.3
  • 123
    • 75149127241 scopus 로고    scopus 로고
    • A simple slot blot for the detection of virtually all subtypes of the influenza A viral hemagglutinins using universal antibodies targeting the fusion peptide
    • C. Li, B. Jaentschke, Y. Song et al., "A simple slot blot for the detection of virtually all subtypes of the influenza A viral hemagglutinins using universal antibodies targeting the fusion peptide," Nature Protocols, vol. 5, no. 1, pp. 14-19, 2010.
    • (2010) Nature Protocols , vol.5 , Issue.1 , pp. 14-19
    • Li, C.1    Jaentschke, B.2    Song, Y.3
  • 124
    • 78649958318 scopus 로고    scopus 로고
    • Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus
    • A. M. Hashem, G. van Domselaar, C. Li et al., "Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus," Biochemical and Biophysical Research Communications, vol. 403, no. 2, pp. 247-251, 2010.
    • (2010) Biochemical and Biophysical Research Communications , vol.403 , Issue.2 , pp. 247-251
    • Hashem, A.M.1    Van Domselaar, G.2    Li, C.3
  • 125
    • 80355149121 scopus 로고    scopus 로고
    • Quantitative analyses of all influenza type A viral hemagglutinins and neuraminidases using universal antibodies in simple slot blot assays
    • C. Gravel, C. Li, J. Wang et al., "Quantitative analyses of all influenza type A viral hemagglutinins and neuraminidases using universal antibodies in simple slot blot assays," Journal of Visualized Experiments, vol. 4, no. 50, article 2784, 2011.
    • (2011) Journal of Visualized Experiments , vol.4 , Issue.50
    • Gravel, C.1    Li, C.2    Wang, J.3
  • 126
    • 62749124125 scopus 로고    scopus 로고
    • Monoclonal antibodies against the fusion peptide of hemagglutinin protect mice from lethal influenza A virus H5N1 infection
    • N. Prabhu, M. Prabakaran, H.-T. Ho et al., "Monoclonal antibodies against the fusion peptide of hemagglutinin protect mice from lethal influenza A virus H5N1 infection," Journal of Virology, vol. 83, no. 6, pp. 2553-2562, 2009.
    • (2009) Journal of Virology , vol.83 , Issue.6 , pp. 2553-2562
    • Prabhu, N.1    Prabakaran, M.2    Ho, H.-T.3
  • 127
    • 84871692172 scopus 로고    scopus 로고
    • Fully human broadly neutralizing monoclonal antibodies against influenza A viruses generated from the memory B cells of a 2009 pandemic H1N1 influenza vaccine recipient
    • W. Hu, A. Chen, Y. Miao et al., "Fully human broadly neutralizing monoclonal antibodies against influenza A viruses generated from the memory B cells of a 2009 pandemic H1N1 influenza vaccine recipient," Virology, vol. 435, no. 2, pp. 320-328, 2013.
    • (2013) Virology , vol.435 , Issue.2 , pp. 320-328
    • Hu, W.1    Chen, A.2    Miao, Y.3
  • 128
    • 0034795117 scopus 로고    scopus 로고
    • Antigenic structure of the haemagglutinin of human influenza A/H2N2 virus
    • E. Tsuchiya, K. Sugawara, S.Hongo et al., "Antigenic structure of the haemagglutinin of human influenza A/H2N2 virus," Journal of General Virology, vol. 82, no. 10, pp. 2475-2484, 2001.
    • (2001) Journal of General Virology , vol.82 , Issue.10 , pp. 2475-2484
    • Tsuchiya, E.1    Sugawara, K.2    Hongo, S.3
  • 129
    • 70350595871 scopus 로고    scopus 로고
    • Hemagglutinin receptor binding avidity drives influenza a virus antigenic drift
    • S. E. Hensley, S. R. Das, A. L. Bailey et al., "Hemagglutinin receptor binding avidity drives influenza a virus antigenic drift," Science, vol. 326, no. 5953, pp. 734-736, 2009.
    • (2009) Science , vol.326 , Issue.5953 , pp. 734-736
    • Hensley, S.E.1    Das, S.R.2    Bailey, A.L.3
  • 130
    • 0030013837 scopus 로고    scopus 로고
    • The immunological activity of a deletion mutant of influenza virus haemagglutinin lacking the globular region
    • H. Sagawa, A. Ohshima, I. Kato, Y. Okuno, and Y. Isegawa, "The immunological activity of a deletion mutant of influenza virus haemagglutinin lacking the globular region," Journal of General Virology, vol. 77, no. 7, pp. 1483-1487, 1996.
    • (1996) Journal of General Virology , vol.77 , Issue.7 , pp. 1483-1487
    • Sagawa, H.1    Ohshima, A.2    Kato, I.3    Okuno, Y.4    Isegawa, Y.5
  • 131
    • 84907682980 scopus 로고    scopus 로고
    • Hemagglutinin stalk domain fromH5N1 strain as a potentially universal antigen
    • K. Uranowska, J. Tyborowska, A. Jurek, B. Szewczyk, and B. Gromadzka, "Hemagglutinin stalk domain fromH5N1 strain as a potentially universal antigen," Acta Biochimica Polonica, vol. 61, no. 3, pp. 541-550, 2014.
    • (2014) Acta Biochimica Polonica , vol.61 , Issue.3 , pp. 541-550
    • Uranowska, K.1    Tyborowska, J.2    Jurek, A.3    Szewczyk, B.4    Gromadzka, B.5
  • 133
    • 84890874733 scopus 로고    scopus 로고
    • Guiding the immune response against influenza virus hemagglutinin toward the conserved stalk domain by hyperglycosylation of the globular head domain
    • D. Eggink, P. H. Goff, and P. Palese, "Guiding the immune response against influenza virus hemagglutinin toward the conserved stalk domain by hyperglycosylation of the globular head domain," Journal of Virology, vol. 88, no. 1, pp. 699-704, 2014.
    • (2014) Journal of Virology , vol.88 , Issue.1 , pp. 699-704
    • Eggink, D.1    Goff, P.H.2    Palese, P.3
  • 134
    • 84899892665 scopus 로고    scopus 로고
    • Glycan masking of hemagglutinin for adenovirus vector and recombinant protein immunizations elicits broadly neutralizing antibodies against H5N1 avian influenza viruses
    • S.-C. Lin,W.-C. Liu, J.-T. Jan, and S.-C.Wu, "Glycan masking of hemagglutinin for adenovirus vector and recombinant protein immunizations elicits broadly neutralizing antibodies against H5N1 avian influenza viruses," PLoS ONE, vol. 9, no. 3, Article ID e92822, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.3
    • Lin, S.-C.1    Liu, W.-C.2    Jan, J.-T.3    Wu, S.-C.4
  • 135
    • 84885950726 scopus 로고    scopus 로고
    • Hemagglutinin stalkbased universal vaccine constructs protect against group 2 influenza A viruses
    • I. Margine, F. Krammer, R. Hai et al., "Hemagglutinin stalkbased universal vaccine constructs protect against group 2 influenza A viruses," Journal of Virology, vol. 87, no. 19, pp. 10435-10446, 2013.
    • (2013) Journal of Virology , vol.87 , Issue.19 , pp. 10435-10446
    • Margine, I.1    Krammer, F.2    Hai, R.3
  • 136
    • 84878611784 scopus 로고    scopus 로고
    • Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies
    • F. Krammer, N. Pica, R. Hai, I. Margine, and P. Palesea, "Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies," Journal of Virology, vol. 87, no. 12, pp. 6542-6550, 2013.
    • (2013) Journal of Virology , vol.87 , Issue.12 , pp. 6542-6550
    • Krammer, F.1    Pica, N.2    Hai, R.3    Margine, I.4    Palesea, P.5
  • 137
    • 84896720073 scopus 로고    scopus 로고
    • Assessment of influenza virus hemagglutinin stalk-based immunity in ferrets
    • F. Krammer, R. Hai, M. Yondola et al., "Assessment of influenza virus hemagglutinin stalk-based immunity in ferrets," Journal of Virology, vol. 88, no. 6, pp. 3432-3442, 2014.
    • (2014) Journal of Virology , vol.88 , Issue.6 , pp. 3432-3442
    • Krammer, F.1    Hai, R.2    Yondola, M.3
  • 138
    • 84862933045 scopus 로고    scopus 로고
    • Multiple-clade H5N1 influenza split vaccine elicits broad cross protection against lethal influenza virus challenge in mice by intranasal vaccination
    • P. Yang, Y. Duan, P. Zhang et al., "Multiple-clade H5N1 influenza split vaccine elicits broad cross protection against lethal influenza virus challenge in mice by intranasal vaccination," PLoS ONE, vol. 7, no. 1,Article ID e30252, 2012.
    • (2012) PLoS ONE , vol.7 , Issue.1
    • Yang, P.1    Duan, Y.2    Zhang, P.3
  • 139
    • 49149087366 scopus 로고    scopus 로고
    • Multivalent HA DNA vaccination protects against highly pathogenic H5N1 avian influenza infection in chickens and mice
    • S. Rao, W.-P. Kong, C.-J. Wei et al., "Multivalent HA DNA vaccination protects against highly pathogenic H5N1 avian influenza infection in chickens and mice," PLoS ONE, vol. 3, no. 6, Article ID e2432, 2008.
    • (2008) PLoS ONE , vol.3 , Issue.6
    • Rao, S.1    Kong, W.-P.2    Wei, C.-J.3
  • 140
    • 84863994618 scopus 로고    scopus 로고
    • A triclade DNA vaccine designed on the basis of a comprehensive serologic study elicits neutralizing antibody responses against all clades and subclades of highly pathogenic avian influenza H5N1 viruses
    • F. Zhou, G. Wang, P. Buchy et al., "A triclade DNA vaccine designed on the basis of a comprehensive serologic study elicits neutralizing antibody responses against all clades and subclades of highly pathogenic avian influenza H5N1 viruses," Journal of Virology, vol. 86, no. 12, pp. 6970-6978, 2012.
    • (2012) Journal of Virology , vol.86 , Issue.12 , pp. 6970-6978
    • Zhou, F.1    Wang, G.2    Buchy, P.3
  • 141
    • 83755225209 scopus 로고    scopus 로고
    • Polyvalent DNA vaccines expressing HA antigens of H5N1 influenza viruses with an optimized leader sequence elicit cross-protective antibody responses
    • S. Wang, A. Hackett, N. Jia et al., "Polyvalent DNA vaccines expressing HA antigens of H5N1 influenza viruses with an optimized leader sequence elicit cross-protective antibody responses," PLoS ONE, vol. 6, no. 12, Article ID e28757, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.12
    • Wang, S.1    Hackett, A.2    Jia, N.3
  • 142
    • 84876986696 scopus 로고    scopus 로고
    • Broadly protective adenovirus-based multivalent vaccines against highly pathogenic avian influenza viruses for pandemic preparedness
    • S. V. Vemula, Y. S. Ahi, A. M. Swaim et al., "Broadly protective adenovirus-based multivalent vaccines against highly pathogenic avian influenza viruses for pandemic preparedness," PLoS ONE, vol. 8, no. 4,Article ID e62496, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.4
    • Vemula, S.V.1    Ahi, Y.S.2    Swaim, A.M.3
  • 143
    • 84907211149 scopus 로고    scopus 로고
    • Progress toward a universal H5N1 vaccine: A recombinant modified vaccinia virusAnkara-expressing trivalent hemagglutinin vaccine
    • M. Prabakaran, S. Leyrer, F. He et al., "Progress toward a universal H5N1 vaccine: a recombinant modified vaccinia virusAnkara-expressing trivalent hemagglutinin vaccine," PLoS ONE, vol. 9, no. 9,Article ID e107316, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.9
    • Prabakaran, M.1    Leyrer, S.2    He, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.