A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  de Marco, Donata ^a   Clementi, Nicola ^a   Mancini, Nicasio ^a   Solforosi, Laura ^a   Moreno, Guisella J ^a   Sun, Xiangjie ^b   Tumpey, Terrence M ^b   Gubareva, Larisa V ^b   Mishin, Vasiliy ^b   Clementi, Massimo ^a   Burioni, Roberto ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY PN SIA49; UNCLASSIFIED DRUG; EPITOPE; HEMAGGLUTININ; INFLUENZA VACCINE; VIRUS ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENETIC CONSERVATION; IMMUNITY; INFLUENZA A (H1N1); INFLUENZA A (H5N1); INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H5N1; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; VIRUS NEUTRALIZATION; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; MUTATION; ORTHOMYXOVIRUS INFECTION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; SERODIAGNOSIS; VIROLOGY;

MUS; ORTHOMYXOVIRIDAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; EPITOPES; FEMALE; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HEMAGGLUTININS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA VACCINES; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; NEUTRALIZATION TESTS; ORTHOMYXOVIRIDAE INFECTIONS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84859364851     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034415     Document Type: Article

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