Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses

PLoS Pathogens

Volumn 8, Issue 12, 2012, Pages

  Tsibane, Tshidi ^a   Ekiert, Damian C ^b   Krause, Jens C ^c   Martinez, Osvaldo ^a   Crowe, James E ^c,d   Wilson, Ian A ^b   Basler, Christopher F ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1F1; UNCLASSIFIED DRUG; VIRUS HEMAGGLUTININ;

ARTICLE; BINDING AFFINITY; BIOSENSOR; CROSS REACTION; CRYSTALLIZATION; GENE MUTATION; HEMAGGLUTINATION INHIBITION; HUMAN; HUMAN CELL; INFLUENZA VIRUS A H1N1; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RECEPTOR BINDING; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; VIRUS CHARACTERIZATION; VIRUS NEUTRALIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; ANTIBODY AFFINITY; BINDING SITES, ANTIBODY; CRYSTALLOGRAPHY, X-RAY; EPITOPES; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; INFLUENZA A VIRUS, H1N1 SUBTYPE; MICE; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, QUATERNARY;

AVES; INFLUENZA A VIRUS; MURINAE;

EID: 84872026547     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003067     Document Type: Article

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