Critical Role of TLR7 Signaling in the Priming of Cross-Protective Cytotoxic T Lymphocyte Responses by a Whole Inactivated Influenza Virus Vaccine

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Budimir, Natalija ^a   de Haan, Aalzen ^a   Meijerhof, Tjarko ^a   Waijer, Simke ^a   Boon, Louis ^b   Gostick, Emma ^c   Price, David A ^c   Wilschut, Jan ^a   Huckriede, Anke ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b BIOCEROS   (Netherlands)

^c CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE MARKER; INFLUENZA VACCINE; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG; WHOLE INACTIVATED INFLUENZA VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS PRESENTATION; CROSS PROTECTION; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; IMMUNE RESPONSE; IN VITRO STUDY; INFLUENZA A (H1N1); INFLUENZA VACCINATION; INFLUENZA VIRUS A H5N1; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; SIGNAL TRANSDUCTION; VIRUS LOAD;

ANIMALS; ANTIGENS, VIRAL; CROSS PROTECTION; CROSS-PRIMING; DENDRITIC CELLS; DOGS; IMMUNIZATION; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; MADIN DARBY CANINE KIDNEY CELLS; MICE; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; T-LYMPHOCYTES, CYTOTOXIC; TOLL-LIKE RECEPTOR 7; VACCINES, INACTIVATED; VIRAL VACCINES;

MUS; ORTHOMYXOVIRIDAE;

EID: 84877067760     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063163     Document Type: Article

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