-
1
-
-
80051670323
-
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
-
Corti D, Voss J, Gamblin SJ, Codoni G, Macagno A, Jarrossay D, Vachieri SG, Pinna D, Minola A, Vanzetta F, Silacci C, Fernandez-Rodriguez BM, Agatic G, Bianchi S, Giacchetto-Sasselli I, Calder L, Sallusto F, Collins P, Haire LF, Temperton N, Langedijk JP, Skehel JJ, Lanzavecchia A. 2011. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 333:850-856.
-
(2011)
Science
, vol.333
, pp. 850-856
-
-
Corti, D.1
Voss, J.2
Gamblin, S.J.3
Codoni, G.4
Macagno, A.5
Jarrossay, D.6
Vachieri, S.G.7
Pinna, D.8
Minola, A.9
Vanzetta, F.10
Silacci, C.11
Fernandez-Rodriguez, B.M.12
Agatic, G.13
Bianchi, S.14
Giacchetto-Sasselli, I.15
Calder, L.16
Sallusto, F.17
Collins, P.18
Haire, L.F.19
Temperton, N.20
Langedijk, J.P.21
Skehel, J.J.22
Lanzavecchia, A.23
more..
-
2
-
-
84866122029
-
Highly conserved protective epitopes on influenza B viruses
-
Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin O, Sieuwerts M, Brakenhoff JP, Vogels R, Li OT, Poon LL, Peiris M, Koudstaal W, Ward AB, Wilson IA, Goudsmit J, Friesen RH. 2012. Highly conserved protective epitopes on influenza B viruses. Science 337:1343-1348.
-
(2012)
Science
, vol.337
, pp. 1343-1348
-
-
Dreyfus, C.1
Laursen, N.S.2
Kwaks, T.3
Zuijdgeest, D.4
Khayat, R.5
Ekiert, D.C.6
Lee, J.H.7
Metlagel, Z.8
Bujny, M.V.9
Jongeneelen, M.10
Van der Vlugt, R.11
Lamrani, M.12
Korse, H.J.13
Geelen, E.14
Sahin, O.15
Sieuwerts, M.16
Brakenhoff, J.P.17
Vogels, R.18
Li, O.T.19
Poon, L.L.20
Peiris, M.21
Koudstaal, W.22
Ward, A.B.23
Wilson, I.A.24
Goudsmit, J.25
Friesen, R.H.26
more..
-
3
-
-
64849114224
-
Antibody recognition of a highly conserved influenza virus epitope
-
Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA. 2009. Antibody recognition of a highly conserved influenza virus epitope. Science 324:246-251.
-
(2009)
Science
, vol.324
, pp. 246-251
-
-
Ekiert, D.C.1
Bhabha, G.2
Elsliger, M.A.3
Friesen, R.H.4
Jongeneelen, M.5
Throsby, M.6
Goudsmit, J.7
Wilson, I.A.8
-
4
-
-
80051635697
-
A highly conserved neutralizing epitope on group 2 influenza A viruses
-
Ekiert DC, Friesen RH, Bhabha G, Kwaks T, Jongeneelen M, Yu W, Ophorst C, Cox F, Korse HJ, Brandenburg B, Vogels R, Brakenhoff JP, Kompier R, Koldijk MH, Cornelissen LA, Poon LL, Peiris M, Koudstaal W, Wilson IA, Goudsmit J. 2011. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 333:843-850.
-
(2011)
Science
, vol.333
, pp. 843-850
-
-
Ekiert, D.C.1
Friesen, R.H.2
Bhabha, G.3
Kwaks, T.4
Jongeneelen, M.5
Yu, W.6
Ophorst, C.7
Cox, F.8
Korse, H.J.9
Brandenburg, B.10
Vogels, R.11
Brakenhoff, J.P.12
Kompier, R.13
Koldijk, M.H.14
Cornelissen, L.A.15
Poon, L.L.16
Peiris, M.17
Koudstaal, W.18
Wilson, I.A.19
Goudsmit, J.20
more..
-
5
-
-
62049083943
-
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
-
Sui J, Hwang WC, Perez S, Wei G, Aird D, Chen LM, Santelli E, Stec B, Cadwell G, Ali M, Wan H, Murakami A, Yammanuru A, Han T, Cox NJ, Bankston LA, Donis RO, Liddington RC, Marasco WA. 2009. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat. Struct. Biol. 16:265-273.
-
(2009)
Nat. Struct. Biol.
, vol.16
, pp. 265-273
-
-
Sui, J.1
Hwang, W.C.2
Perez, S.3
Wei, G.4
Aird, D.5
Chen, L.M.6
Santelli, E.7
Stec, B.8
Cadwell, G.9
Ali, M.10
Wan, H.11
Murakami, A.12
Yammanuru, A.13
Han, T.14
Cox, N.J.15
Bankston, L.A.16
Donis, R.O.17
Liddington, R.C.18
Marasco, W.A.19
-
6
-
-
77957678820
-
Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivorbased libraries
-
Kashyap AK, Steel J, Rubrum A, Estelles A, Briante R, Ilyushina NA, Xu L, Swale RE, Faynboym AM, Foreman PK, Horowitz M, Horowitz L, Webby R, Palese P, Lerner RA, Bhatt RR. 2010. Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivorbased libraries. PLoS Pathog. 6:e1000990.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Kashyap, A.K.1
Steel, J.2
Rubrum, A.3
Estelles, A.4
Briante, R.5
Ilyushina, N.A.6
Xu, L.7
Swale, R.E.8
Faynboym, A.M.9
Foreman, P.K.10
Horowitz, M.11
Horowitz, L.12
Webby, R.13
Palese, P.14
Lerner, R.A.15
Bhatt, R.R.16
-
7
-
-
0027471177
-
A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains
-
Okuno Y, Isegawa Y, Sasao F, Ueda S. 1993. A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains. J. Virol. 67:2552-2558.
-
(1993)
J. Virol.
, vol.67
, pp. 2552-2558
-
-
Okuno, Y.1
Isegawa, Y.2
Sasao, F.3
Ueda, S.4
-
8
-
-
84873061860
-
Monoclonal antibody C179 product information sheet
-
Takara Bio Inc., Takara Bio Inc., Shiga, Japan
-
Takara Bio Inc. Monoclonal antibody C179 product information sheet. Takara Bio Inc., Shiga, Japan. http://catalog.takara-bio.co.jp/en/PDFFiles/M145_DS_e.pdf.
-
-
-
-
9
-
-
78650231989
-
A cross-reactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus infection
-
Sakabe S, Iwatsuki-Horimoto K, Horimoto T, Nidom CA, Le MQ, Takano R, Kubota-Koketsu R, Okuno Y, Ozawa M, Kawaoka Y. 2010. A cross-reactive neutralizing monoclonal antibody protects mice from H5N1 and pandemic (H1N1) 2009 virus infection. Antiviral Res. 88:249-255.
-
(2010)
Antiviral Res.
, vol.88
, pp. 249-255
-
-
Sakabe, S.1
Iwatsuki-Horimoto, K.2
Horimoto, T.3
Nidom, C.A.4
Le, M.Q.5
Takano, R.6
Kubota-Koketsu, R.7
Okuno, Y.8
Ozawa, M.9
Kawaoka, Y.10
-
10
-
-
0032822080
-
An epitope shared by the hemagglutinins of H1, H2, H5, and H6 subtypes of influenza A virus
-
Smirnov YA, Lipatov AS, Gitelman AK, Okuno Y, Van Beek R, Osterhaus AD, Claas EC. 1999. An epitope shared by the hemagglutinins of H1, H2, H5, and H6 subtypes of influenza A virus. Acta Virol. 43:237-244.
-
(1999)
Acta Virol.
, vol.43
, pp. 237-244
-
-
Smirnov, Y.A.1
Lipatov, A.S.2
Gitelman, A.K.3
Okuno, Y.4
Van Beek, R.5
Osterhaus, A.D.6
Claas, E.C.7
-
11
-
-
84878578705
-
DNA coding for variable region to human influenza A type virus
-
November, US patent 5684146
-
Kato I, Okuno Y, Oshima A, Takabatake T, Yoshioka H. November 1997.DNA coding for variable region to human influenza A type virus. US patent 5684146.
-
(1997)
-
-
Kato, I.1
Okuno, Y.2
Oshima, A.3
Takabatake, T.4
Yoshioka, H.5
-
13
-
-
34447508216
-
Phaser crystallographic software
-
McCoy AJ, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC, Read RJ. 2007. Phaser crystallographic software. J. Appl. Crystallogr. 40: 658-674.
-
(2007)
J. Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
Winn, M.D.4
Storoni, L.C.5
Read, R.J.6
-
14
-
-
76449098262
-
PHENIX: a comprehensive Pythonbased system for macromolecular structure solution
-
Adams PD, Afonine PV, Bunkoczi G, Chen VB, Davis IW, Echols N, Headd JJ, Hung LW, Kapral GJ, Grosse-Kunstleve RW, McCoy AJ, Moriarty NW, Oeffner R, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH. 2010. PHENIX: a comprehensive Pythonbased system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66:213-221.
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkoczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
McCoy, A.J.11
Moriarty, N.W.12
Oeffner, R.13
Read, R.J.14
Richardson, D.C.15
Richardson, J.S.16
Terwilliger, T.C.17
Zwart, P.H.18
-
16
-
-
0028304962
-
Satisfying hydrogen bonding potential in proteins
-
McDonald IK, Thornton JM. 1994. Satisfying hydrogen bonding potential in proteins. J. Mol. Biol. 238:777-793.
-
(1994)
J. Mol. Biol.
, vol.238
, pp. 777-793
-
-
McDonald, I.K.1
Thornton, J.M.2
-
17
-
-
0023660979
-
Structure of myohemerythrin in the azidomet state at 1.7/1.3 Å resolution
-
Sheriff S, Hendrickson WA, Smith JL. 1987. Structure of myohemerythrin in the azidomet state at 1.7/1.3 Å resolution. J. Mol. Biol. 197:273-296.
-
(1987)
J. Mol. Biol.
, vol.197
, pp. 273-296
-
-
Sheriff, S.1
Hendrickson, W.A.2
Smith, J.L.3
-
18
-
-
0000538815
-
Analytical molecular surface calculation
-
Connolly M. 1983. Analytical molecular surface calculation. J. Appl. Crystallogr. 16:548-558.
-
(1983)
J. Appl. Crystallogr.
, vol.16
, pp. 548-558
-
-
Connolly, M.1
-
19
-
-
48049124972
-
Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains
-
Abhinandan KR, Martin AC. 2008. Analysis and improvements to Kabat and structurally correct numbering of antibody variable domains. Mol. Immunol. 45:3832-3839.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 3832-3839
-
-
Abhinandan, K.R.1
Martin, A.C.2
-
20
-
-
74549178560
-
MolProbity: allatom structure validation for macromolecular crystallography
-
Chen VB, Arendall WB, III, Headd JJ, Keedy DA, Immormino RM, Kapral GJ, Murray LW, Richardson JS, Richardson DC. 2010. MolProbity: allatom structure validation for macromolecular crystallography. Acta Crystallogr. D Biol. Crystallogr. 66:12-21.
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 12-21
-
-
Chen, V.B.1
Arendall III, W.B.2
Headd, J.J.3
Keedy, D.A.4
Immormino, R.M.5
Kapral, G.J.6
Murray, L.W.7
Richardson, J.S.8
Richardson, D.C.9
-
21
-
-
37849052232
-
The influenza virus resource at the National Center for Biotechnology Information
-
Bao Y, Bolotov P, Dernovoy D, Kiryutin B, Zaslavsky L, Tatusova T, Ostell J, Lipman D. 2008. The influenza virus resource at the National Center for Biotechnology Information. J. Virol. 82:596-601.
-
(2008)
J. Virol.
, vol.82
, pp. 596-601
-
-
Bao, Y.1
Bolotov, P.2
Dernovoy, D.3
Kiryutin, B.4
Zaslavsky, L.5
Tatusova, T.6
Ostell, J.7
Lipman, D.8
-
22
-
-
3042666256
-
MUSCLE: multiple sequence alignment with high accuracy and high throughput
-
Edgar RC. 2004. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32:1792-1797.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1792-1797
-
-
Edgar, R.C.1
-
23
-
-
34548496893
-
Fc receptor but not complement binding is important in antibody protection against HIV
-
Hessell AJ, Hangartner L, Hunter M, Havenith CE, Beurskens FJ, Bakker JM, Lanigan CM, Landucci G, Forthal DN, Parren PW, Marx PA, Burton DR. 2007. Fc receptor but not complement binding is important in antibody protection against HIV. Nature 449:101-104.
-
(2007)
Nature
, vol.449
, pp. 101-104
-
-
Hessell, A.J.1
Hangartner, L.2
Hunter, M.3
Havenith, C.E.4
Beurskens, F.J.5
Bakker, J.M.6
Lanigan, C.M.7
Landucci, G.8
Forthal, D.N.9
Parren, P.W.10
Marx, P.A.11
Burton, D.R.12
-
24
-
-
0000330205
-
On the use of the merging R factor as a quality indicator for X-ray data
-
Weiss MS, Hilgenfeld R. 1997. On the use of the merging R factor as a quality indicator for X-ray data. J. Appl. Crystallog. 30:203-205.
-
(1997)
J. Appl. Crystallog.
, vol.30
, pp. 203-205
-
-
Weiss, M.S.1
Hilgenfeld, R.2
-
25
-
-
75449093578
-
Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic
-
Xu R, McBride R, Paulson JC, Basler CF, Wilson IA. 2010. Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. J. Virol. 84:1715-1721.
-
(2010)
J. Virol.
, vol.84
, pp. 1715-1721
-
-
Xu, R.1
McBride, R.2
Paulson, J.C.3
Basler, C.F.4
Wilson, I.A.5
-
26
-
-
70350132189
-
Structures of receptor complexes formed by hemagglutinins from the Asian influenza pandemic of 1957
-
Liu J, Stevens DJ, Haire LF, Walker PA, Coombs PJ, Russell RJ, Gamblin SJ, Skehel JJ. 2009. Structures of receptor complexes formed by hemagglutinins from the Asian influenza pandemic of 1957. Proc. Natl. Acad. Sci. U. S. A. 106:17175-17180.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 17175-17180
-
-
Liu, J.1
Stevens, D.J.2
Haire, L.F.3
Walker, P.A.4
Coombs, P.J.5
Russell, R.J.6
Gamblin, S.J.7
Skehel, J.J.8
-
27
-
-
0033857323
-
Prevention and treatment of bronchopneumonia in mice caused by mouse-adapted variant of avian H5N2 influenza A virus using monoclonal antibody against conserved epitope in theHAstem region
-
Smirnov YA, Lipatov AS, Gitelman AK, Claas EC, Osterhaus AD. 2000. Prevention and treatment of bronchopneumonia in mice caused by mouse-adapted variant of avian H5N2 influenza A virus using monoclonal antibody against conserved epitope in theHAstem region. Arch. Virol. 145:1733-1741.
-
(2000)
Arch. Virol.
, vol.145
, pp. 1733-1741
-
-
Smirnov, Y.A.1
Lipatov, A.S.2
Gitelman, A.K.3
Claas, E.C.4
Osterhaus, A.D.5
-
28
-
-
78651488739
-
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
-
Wrammert J, Koutsonanos D, Li GM, Edupuganti S, Sui J, Morrissey M, McCausland M, Skountzou I, Hornig M, Lipkin WI, Mehta A, Razavi B, Del Rio C, Zheng NY, Lee JH, Huang M, Ali Z, Kaur K, Andrews S, Amara RR, Wang Y, Das SR, O'Donnell CD, Yewdell JW, Subbarao K, Marasco WA, Mulligan MJ, Compans R, Ahmed R, Wilson PC. 2011. Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. J. Exp. Med. 208:181-193.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 181-193
-
-
Wrammert, J.1
Koutsonanos, D.2
Li, G.M.3
Edupuganti, S.4
Sui, J.5
Morrissey, M.6
McCausland, M.7
Skountzou, I.8
Hornig, M.9
Lipkin, W.I.10
Mehta, A.11
Razavi, B.12
Del Rio, C.13
Zheng, N.Y.14
Lee, J.H.15
Huang, M.16
Ali, Z.17
Kaur, K.18
Andrews, S.19
Amara, R.R.20
Wang, Y.21
Das, S.R.22
O'Donnell, C.D.23
Yewdell, J.W.24
Subbarao, K.25
Marasco, W.A.26
Mulligan, M.J.27
Compans, R.28
Ahmed, R.29
Wilson, P.C.30
more..
-
29
-
-
84866953140
-
Cross-neutralization of influenza A viruses mediated by a single antibody loop
-
Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA. 2012. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature 489:526-532.
-
(2012)
Nature
, vol.489
, pp. 526-532
-
-
Ekiert, D.C.1
Kashyap, A.K.2
Steel, J.3
Rubrum, A.4
Bhabha, G.5
Khayat, R.6
Lee, J.H.7
Dillon, M.A.8
O'Neil, R.E.9
Faynboym, A.M.10
Horowitz, M.11
Horowitz, L.12
Ward, A.B.13
Palese, P.14
Webby, R.15
Lerner, R.A.16
Bhatt, R.R.17
Wilson, I.A.18
-
30
-
-
77956379133
-
Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge
-
Bommakanti G, Citron MP, Hepler RW, Callahan C, Heidecker GJ, Najar TA, Lu X, Joyce JG, Shiver JW, Casimiro DR, ter Meulen J, Liang X, Varadarajan R. 2010. Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge. Proc. Natl. Acad. Sci. U. S. A. 107:13701-13706.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 13701-13706
-
-
Bommakanti, G.1
Citron, M.P.2
Hepler, R.W.3
Callahan, C.4
Heidecker, G.J.5
Najar, T.A.6
Lu, X.7
Joyce, J.G.8
Shiver, J.W.9
Casimiro, D.R.10
Ter Meulen, J.11
Liang, X.12
Varadarajan, R.13
-
31
-
-
84862025262
-
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
-
Whitehead TA, Chevalier A, Song Y, Dreyfus C, Fleishman SJ, De Mattos C, Myers CA, Kamisetty H, Blair P, Wilson IA, Baker D. 2012. Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. Nat. Biotechnol. 30:543-548.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 543-548
-
-
Whitehead, T.A.1
Chevalier, A.2
Song, Y.3
Dreyfus, C.4
Fleishman, S.J.5
De Mattos, C.6
Myers, C.A.7
Kamisetty, H.8
Blair, P.9
Wilson, I.A.10
Baker, D.11
-
32
-
-
79956017135
-
Computational design of proteins targeting the conserved stem region of influenza hemagglutinin
-
Fleishman SJ, Whitehead TA, Ekiert DC, Dreyfus C, Corn JE, Strauch EM, Wilson IA, Baker D. 2011. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science 332: 816-821.
-
(2011)
Science
, vol.332
, pp. 816-821
-
-
Fleishman, S.J.1
Whitehead, T.A.2
Ekiert, D.C.3
Dreyfus, C.4
Corn, J.E.5
Strauch, E.M.6
Wilson, I.A.7
Baker, D.8
|