Pharmacological recruitment of aldehyde dehydrogenase 3A1 (ALDH3A1) to assist ALDH2 in acetaldehyde and ethanol metabolism in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 10, 2015, Pages 3074-3079

  Chen, Che Hong ^a   Cruz, Leslie A ^a   Mochly Rosen, Daria ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetaldehyde; Alda; ALDH2; ALDH3A1; Ethanol metabolism

Indexed keywords

AGENTS AFFECTING METABOLISM; ALDA 1; ALDA 89; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; ALDEHYDE DEHYDROGENASE ISOENZYME 3A1; UNCLASSIFIED DRUG; ALCOHOL; ALDEHYDE DEHYDROGENASE 2, MOUSE; ALDH3A1 PROTEIN, HUMAN; PROTEIN BINDING;

ALCOHOL BLOOD LEVEL; ALCOHOL INTOXICATION; ALCOHOL METABOLISM; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; ESOPHAGUS; ISOELECTRIC FOCUSING; LIVER HOMOGENATE; MALE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; TISSUE HOMOGENATE; ANIMAL; DRUG EFFECTS; HUMAN; METABOLISM; TRANSGENIC MOUSE;

MUS;

ALDEHYDE DEHYDROGENASE; ANIMALS; ETHANOL; HUMANS; MICE; MICE, TRANSGENIC; PROTEIN BINDING;

EID: 84924308121     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414657112     Document Type: Article

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