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Volumn 61, Issue 3, 2000, Pages 192-198

Polymorphisms of human aldehyde dehydrogenases: Consequences for drug metabolism and disease

Author keywords

Alcoholism; Aldehyde dehydrogenases; Genetic polymorphisms; Metabolic diseases

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DERIVATIVE; ISOENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 0033824324     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028400     Document Type: Review
Times cited : (141)

References (48)
  • 1
    • 0026655335 scopus 로고
    • Aldehyde dehydrogenases and their role in carcinogenesis
    • Lindahl R: Aldehyde dehydrogenases and their role in carcinogenesis. Crit Rev Biochem Mol Biol 1992;27:283-335.
    • (1992) Crit Rev Biochem Mol Biol , vol.27 , pp. 283-335
    • Lindahl, R.1
  • 2
    • 0032958632 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
    • Niederreither K, Subbarayan V, Dolle P, Chambon P: Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet 1999;21:444-448.
    • (1999) Nat Genet , vol.21 , pp. 444-448
    • Niederreither, K.1    Subbarayan, V.2    Dolle, P.3    Chambon, P.4
  • 3
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal malondialdehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H: Chemistry and biochemistry of 4-hydroxynonenal malondialdehyde and related aldehydes. Free Rad Biol Med 1991;11:81-128.
    • (1991) Free Rad Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 4
    • 0032859206 scopus 로고    scopus 로고
    • Eukaryotic aldehyde dehydrogenase (ALDH) genes: Human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping
    • Vasiliou V, Bairoch A, Tipton KF, Nebert DW: Eukaryotic aldehyde dehydrogenase (ALDH) genes: Human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping. Pharmacogenetics 1999;9:421-434.
    • (1999) Pharmacogenetics , vol.9 , pp. 421-434
    • Vasiliou, V.1    Bairoch, A.2    Tipton, K.F.3    Nebert, D.W.4
  • 6
    • 0002802354 scopus 로고
    • Aldehyde dehydrogenase genes: Classification based on evolution, structure and regulation
    • Vasiliou V, Weiner H, Marselos M, Nebert DW: Aldehyde dehydrogenase genes: Classification based on evolution, structure and regulation. Eur J Drug Metabol Pharmacokinet 1995;20:53-64.
    • (1995) Eur J Drug Metabol Pharmacokinet , vol.20 , pp. 53-64
    • Vasiliou, V.1    Weiner, H.2    Marselos, M.3    Nebert, D.W.4
  • 8
    • 0033585012 scopus 로고    scopus 로고
    • Metabolism of retinaldehyde and other aldehydes in soluble extracts of human liver and kidney
    • Ambroziak W, Izaguirre G, Pietruszko R: Metabolism of retinaldehyde and other aldehydes in soluble extracts of human liver and kidney. J Biol Chem 1999;274:33366-33373.
    • (1999) J Biol Chem , vol.274 , pp. 33366-33373
    • Ambroziak, W.1    Izaguirre, G.2    Pietruszko, R.3
  • 10
    • 0031785157 scopus 로고    scopus 로고
    • The T-cell oncogenic protein HOX11 activates Aldh1 expression in NIH 3T3 cells but represses its expression in mouse spleen development
    • Greene WK, Bahn S, Masson N, Rabbitts TH: The T-cell oncogenic protein HOX11 activates Aldh1 expression in NIH 3T3 cells but represses its expression in mouse spleen development. Mol Cell Biol 1998;18:7030-7037.
    • (1998) Mol Cell Biol , vol.18 , pp. 7030-7037
    • Greene, W.K.1    Bahn, S.2    Masson, N.3    Rabbitts, T.H.4
  • 12
    • 0032873333 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines
    • Sladek NE: Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines. Curr Pharm Des 1999;5:607-625.
    • (1999) Curr Pharm Des , vol.5 , pp. 607-625
    • Sladek, N.E.1
  • 13
    • 0026907527 scopus 로고
    • Molecular genetics of human aldehyde dehydrogenase
    • Yoshida A: Molecular genetics of human aldehyde dehydrogenase. Pharmacogenetics 1992; 2:139-147.
    • (1992) Pharmacogenetics , vol.2 , pp. 139-147
    • Yoshida, A.1
  • 14
    • 0029073223 scopus 로고
    • The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme
    • Stewart MJ, Malek K, Xiao Q, Dipple KM, Crabb DW: The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme. Biochem Biophys Res Commun 1995;211:144-151.
    • (1995) Biochem Biophys Res Commun , vol.211 , pp. 144-151
    • Stewart, M.J.1    Malek, K.2    Xiao, Q.3    Dipple, K.M.4    Crabb, D.W.5
  • 15
    • 0027379707 scopus 로고
    • Diverse polymorphism within a short coding region of the human aldehyde dehydrogenase-5 (ALDH5) gene
    • Sherman D, Dave V, Hsu LC, Peters TJ, Yoshida A: Diverse polymorphism within a short coding region of the human aldehyde dehydrogenase-5 (ALDH5) gene. Hum Genet 1993;92: 477-480.
    • (1993) Hum Genet , vol.92 , pp. 477-480
    • Sherman, D.1    Dave, V.2    Hsu, L.C.3    Peters, T.J.4    Yoshida, A.5
  • 16
    • 0018687218 scopus 로고
    • Racial differences in alcohol sensitivity: A new hypothesis
    • Goedde HW, Harada S, Agarwal DP: Racial differences in alcohol sensitivity: A new hypothesis. Hum Genet 1979;51:331-334.
    • (1979) Hum Genet , vol.51 , pp. 331-334
    • Goedde, H.W.1    Harada, S.2    Agarwal, D.P.3
  • 17
    • 0022362004 scopus 로고
    • Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases
    • Yoshida A, Ikawa M, Hsu LC, Tani K: Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases. Alcohol 1985;2: 103-106.
    • (1985) Alcohol , vol.2 , pp. 103-106
    • Yoshida, A.1    Ikawa, M.2    Hsu, L.C.3    Tani, K.4
  • 18
    • 0032847525 scopus 로고    scopus 로고
    • Effects of worldwide population subdivision on ALDH2 linkage disequilibrium
    • Peterson RJ, Goldman D, Long JC: Effects of worldwide population subdivision on ALDH2 linkage disequilibrium. Genome Res 1999;9: 844-852.
    • (1999) Genome Res , vol.9 , pp. 844-852
    • Peterson, R.J.1    Goldman, D.2    Long, J.C.3
  • 22
    • 0032421003 scopus 로고    scopus 로고
    • Effects on sister chromatid exchange frequency of aldehyde dehydrogenase 2 genotype and smoking in vinyl chloride workers
    • Wong RH, Wang JD, Hsieh LL, Du CL, Cheng TJ: Effects on sister chromatid exchange frequency of aldehyde dehydrogenase 2 genotype and smoking in vinyl chloride workers. Mutat Res 1998;420:99-107.
    • (1998) Mutat Res , vol.420 , pp. 99-107
    • Wong, R.H.1    Wang, J.D.2    Hsieh, L.L.3    Du, C.L.4    Cheng, T.J.5
  • 24
    • 0028275147 scopus 로고
    • Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase: A model to study human (Oriental type) class 2 aldehyde dehydrogenase
    • Farres J, Wang X, Takahashi K, Cunningham SJ, Wang TT, Weiner H: Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase: A model to study human (Oriental type) class 2 aldehyde dehydrogenase. J Biol Chem 1994; 269:13854-13860.
    • (1994) J Biol Chem , vol.269 , pp. 13854-13860
    • Farres, J.1    Wang, X.2    Takahashi, K.3    Cunningham, S.J.4    Wang, T.T.5    Weiner, H.6
  • 25
    • 0023812997 scopus 로고
    • Formation of interstrand cross-links in chloroacetaldehyde-treated DNA demonstrated by ethidium bromide fluorescence
    • Spengler SJ, Singer B: Formation of interstrand cross-links in chloroacetaldehyde-treated DNA demonstrated by ethidium bromide fluorescence. Cancer Res 1988;48:4804-4806.
    • (1988) Cancer Res , vol.48 , pp. 4804-4806
    • Spengler, S.J.1    Singer, B.2
  • 27
    • 0032978478 scopus 로고    scopus 로고
    • A novel polymorphism (-357 G/A) of the ALDH2 gene: Linkage disequilibrium and an association with alcoholism
    • Harada S, Okubo T, Nakamura T, Fujii C, Nomura F, Higuchi S, Tsutsumi M: A novel polymorphism (-357 G/A) of the ALDH2 gene: Linkage disequilibrium and an association with alcoholism. Alcohol Clin Exp Res 1999; 23:958-962.
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 958-962
    • Harada, S.1    Okubo, T.2    Nakamura, T.3    Fujii, C.4    Nomura, F.5    Higuchi, S.6    Tsutsumi, M.7
  • 28
    • 0032982139 scopus 로고    scopus 로고
    • An A/G polymorphism in the promoter of mitochondrial aldehyde dehydrogenase (ALDH2): Effects of the sequence variant on transcription factor binding and promoter strength
    • Chou WY, Stewart MJ, Carr LG, Zheng D, Stewart TR, Williams A, Pinaire J, Crabb DW: An A/G polymorphism in the promoter of mitochondrial aldehyde dehydrogenase (ALDH2): Effects of the sequence variant on transcription factor binding and promoter strength. Alcohol Clin Exp Res 1999;23:963-968.
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 963-968
    • Chou, W.Y.1    Stewart, M.J.2    Carr, L.G.3    Zheng, D.4    Stewart, T.R.5    Williams, A.6    Pinaire, J.7    Crabb, D.W.8
  • 29
    • 0028926805 scopus 로고
    • Polymorphism of a class 3 aldehyde dehydrogenase present in human saliva and in hair roots
    • Dyck LE: Polymorphism of a class 3 aldehyde dehydrogenase present in human saliva and in hair roots. Alcohol Clin Exp Res 1995;19:420-426.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 420-426
    • Dyck, L.E.1
  • 32
    • 0033233482 scopus 로고    scopus 로고
    • The molecular basis of Sjögren-Larsson syndrome: Mutation analysis of the fatty aldehyde dehydrogenase gene
    • Rizzo WB, Carney G, Lin Z: The molecular basis of Sjögren-Larsson syndrome: Mutation analysis of the fatty aldehyde dehydrogenase gene. Am J Hum Genet 1999:65:1547-1560.
    • (1999) Am J Hum Genet , vol.65 , pp. 1547-1560
    • Rizzo, W.B.1    Carney, G.2    Lin, Z.3
  • 33
    • 0022970206 scopus 로고
    • Purification and characterization of human liver 'high Km' aldehyde dehydrogenase and its identification as glutamine gamma-semialdehyde dehydrogenase
    • Forte-McRobbie CM, Pietruszko R: Purification and characterization of human liver 'high Km' aldehyde dehydrogenase and its identification as glutamine gamma-semialdehyde dehydrogenase. J Biol Chem 1986;261:2154-2163.
    • (1986) J Biol Chem , vol.261 , pp. 2154-2163
    • Forte-McRobbie, C.M.1    Pietruszko, R.2
  • 34
    • 0029922882 scopus 로고    scopus 로고
    • Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase
    • Hu CA, Lin WW, Valle D: Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase. J Biol Chem 1996;271:9795-9800.
    • (1996) J Biol Chem , vol.271 , pp. 9795-9800
    • Hu, C.A.1    Lin, W.W.2    Valle, D.3
  • 35
    • 0017136450 scopus 로고
    • Type II hyperprolinemia: Deltal-pyrroline-5-carboxylic acid dehydrogenase deficiency in cultured skin fibroblasts and circulating lymphocytes
    • Valle D, Goodman SI, Applegarth DA, Shih VE, Phang JM: Type II hyperprolinemia: Deltal-pyrroline-5-carboxylic acid dehydrogenase deficiency in cultured skin fibroblasts and circulating lymphocytes. J Clin Invest 1976;58: 598-603.
    • (1976) J Clin Invest , vol.58 , pp. 598-603
    • Valle, D.1    Goodman, S.I.2    Applegarth, D.A.3    Shih, V.E.4    Phang, J.M.5
  • 37
    • 0029092806 scopus 로고
    • Enzymatic and immunologic identification of succinic semialdehyde dehydrogenase in rat and human neural and non-neural tissues
    • Chambliss KL, Zhang YA, Rossier E, Vollmer B, Gibson KM: Enzymatic and immunologic identification of succinic semialdehyde dehydrogenase in rat and human neural and non-neural tissues. J Neurochem 1995;65:851-855.
    • (1995) J Neurochem , vol.65 , pp. 851-855
    • Chambliss, K.L.1    Zhang, Y.A.2    Rossier, E.3    Vollmer, B.4    Gibson, K.M.5
  • 38
    • 0031887260 scopus 로고    scopus 로고
    • 4-Hydroxybutyric acid and the clinical phenotype of succinic semialdehyde dehydrogenase deficiency, an inborn error of GABA metabolism
    • Gibson KM, Hoffmann GF, Hodson AK, Bottiglieri T, Jakobs C: 4-Hydroxybutyric acid and the clinical phenotype of succinic semialdehyde dehydrogenase deficiency, an inborn error of GABA metabolism. Neuropediatrics 1998;29:14-22.
    • (1998) Neuropediatrics , vol.29 , pp. 14-22
    • Gibson, K.M.1    Hoffmann, G.F.2    Hodson, A.K.3    Bottiglieri, T.4    Jakobs, C.5
  • 39
    • 0032231363 scopus 로고    scopus 로고
    • Two exon-skipping mutations as the molecular basis of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria)
    • Chambliss KL, Hinson DD, Trettel F, Malaspina P, Novelletto A, Jakobs C, Gibson KM: Two exon-skipping mutations as the molecular basis of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria). Am J Hum Genet 1998;63:399-408.
    • (1998) Am J Hum Genet , vol.63 , pp. 399-408
    • Chambliss, K.L.1    Hinson, D.D.2    Trettel, F.3    Malaspina, P.4    Novelletto, A.5    Jakobs, C.6    Gibson, K.M.7
  • 40
    • 0026671544 scopus 로고
    • CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. CDNA cloning, evolutionary relationships, and tissue distribution
    • Kedishvili NY, Popov KM, Rougraff PM, Zhao Y, Crabb DW, Harris RA: CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution. J Biol Chem 1992;267:19724-19729.
    • (1992) J Biol Chem , vol.267 , pp. 19724-19729
    • Kedishvili, N.Y.1    Popov, K.M.2    Rougraff, P.M.3    Zhao, Y.4    Crabb, D.W.5    Harris, R.A.6
  • 41
    • 0031737815 scopus 로고    scopus 로고
    • Methylmalonic semialdehyde dehydrogenase deficiency: Psychomotor delay and methylmalonic aciduria without metabolic decompensation
    • Roe CR, Struys E, Kok RM, Roe DS, Harris RA, Jakobs C: Methylmalonic semialdehyde dehydrogenase deficiency: Psychomotor delay and methylmalonic aciduria without metabolic decompensation. Mol Genet Metab 1998;65: 35-43.
    • (1998) Mol Genet Metab , vol.65 , pp. 35-43
    • Roe, C.R.1    Struys, E.2    Kok, R.M.3    Roe, D.S.4    Harris, R.A.5    Jakobs, C.6
  • 42
    • 0027401783 scopus 로고
    • Metabolic role of aldehyde dehydrogenase
    • Ambroziak W, Pietruszko R: Metabolic role of aldehyde dehydrogenase. Adv Exp Med Biol 1993;328:5-15.
    • (1993) Adv Exp Med Biol , vol.328 , pp. 5-15
    • Ambroziak, W.1    Pietruszko, R.2
  • 43
    • 0034629439 scopus 로고    scopus 로고
    • Molecular and biochemical characterization of rat gamma-trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis
    • Vaz FM, Fouchier SW, Ofman R, Sommer M, Wanders RJ: Molecular and biochemical characterization of rat gamma-trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis. J Biol Chem 2000;275:7390-7394.
    • (2000) J Biol Chem , vol.275 , pp. 7390-7394
    • Vaz, F.M.1    Fouchier, S.W.2    Ofman, R.3    Sommer, M.4    Wanders, R.J.5
  • 44
    • 0030585739 scopus 로고    scopus 로고
    • Human gamma-aminobutyraldehyde dehydrogenase (ALDH9): CDNA sequence, genomic organization, polymorphism, chromosomal localization, and tissue expression
    • Lin SW, Chen JC, Hsu LC, Hsieh CL, Yoshida A: Human gamma-aminobutyraldehyde dehydrogenase (ALDH9): cDNA sequence, genomic organization, polymorphism, chromosomal localization, and tissue expression. Genomics 1996;34:376-380.
    • (1996) Genomics , vol.34 , pp. 376-380
    • Lin, S.W.1    Chen, J.C.2    Hsu, L.C.3    Hsieh, C.L.4    Yoshida, A.5
  • 45
    • 0033282003 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase gene superfamily: The 1998 update
    • Ziegler TL, Vasiliou V: Aldehyde dehydrogenase gene superfamily: The 1998 update. Adv Exp Med Biol 1999;463:255-263.
    • (1999) Adv Exp Med Biol , vol.463 , pp. 255-263
    • Ziegler, T.L.1    Vasiliou, V.2
  • 46
    • 0032748555 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist?
    • Nebert DW: Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist? Clin Genet 1999;56:247-258.
    • (1999) Clin Genet , vol.56 , pp. 247-258
    • Nebert, D.W.1
  • 47
    • 0034624762 scopus 로고    scopus 로고
    • N-Terminal dipeptides of D(-)-penicillamine as sequestration agents for acetaldehyde
    • Cohen JF, Elberling JA, DeMaster EG, Lin RC, Nagasawa HT: N-Terminal dipeptides of D(-)-penicillamine as sequestration agents for acetaldehyde. J Med Chem 2000;43:1029-1033.
    • (2000) J Med Chem , vol.43 , pp. 1029-1033
    • Cohen, J.F.1    Elberling, J.A.2    DeMaster, E.G.3    Lin, R.C.4    Nagasawa, H.T.5


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