Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain

Science Translational Medicine

Volumn 6, Issue 251, 2014, Pages

  Zambelli, Vanessa O ^a,b   Gross, Eric R ^a   Chen, Che Hong ^a   Gutierrez, Vanessa P ^b   Cury, Yara ^b   Mochly Rosen, Daria ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTO BUTANTAN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; ACETALDEHYDE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; ANTINOCICEPTIVE AGENT; EARLY GROWTH RESPONSE FACTOR 1; FORMALDEHYDE; N (1,3 BENZODIOXOL 5 YLMETHYL) 2,6 DICHLOROBENZAMIDE; UNCLASSIFIED DRUG; 1,3 BENZODIOXOLE DERIVATIVE; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 2, MOUSE; ALDH2 PROTEIN, RAT; BENZAMIDE DERIVATIVE; MITOCHONDRIAL PROTEIN; N-(1,3-BENZODIOXOL-5-YLMETHYL)-2,6-DICHLOROBENZAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HETEROZYGOTE; HYPERALGESIA; INFLAMMATORY PAIN; MOUSE; NOCICEPTION; NONHUMAN; OPEN FIELD TEST; PAIN THRESHOLD; PAW EDEMA; POINT MUTATION; RAT; RODENT MODEL; ROTAROD TEST; SPINAL CORD; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; INFLAMMATION; METABOLISM; PAIN; PATHOLOGY;

ACETALDEHYDE; ACUTE PAIN; ALDEHYDE DEHYDROGENASE; ANIMALS; BEHAVIOR, ANIMAL; BENZAMIDES; BENZODIOXOLES; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; FORMALDEHYDE; HETEROZYGOTE; HYPERALGESIA; INFLAMMATION; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; NOCICEPTION; RATS;

EID: 84907437979     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3009539     Document Type: Article

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