Paired acute inhalation test reveals that acetaldehyde toxicity is higher in aldehyde dehydrogenase 2 knockout mice than in wild-type mice

Journal of Toxicological Sciences

Volumn 30, Issue 4, 2005, Pages 329-337

  Isse, Toyohi ^a   Oyama, Tsunchiro ^a   Matsuno, Koji ^b   Ogawa, Masanori ^a   Narai Suzuki, Ric ^a   Yamaguchi, Tetsunosuke ^a   Murakami, Tomoe ^a   Kinaga, Tsuyoshi ^a   Uchiyama, Iwao ^c   Kawamoto, Toshihiro ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Acetaldehyde; Acute toxic class method (OECD); Aldehyde dehydrogenase 2; Toxicokinetics; Transgenic models knockouts

Indexed keywords

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE ISOENZYME 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY POSTURE; BRADYPNEA; BREATHING DISORDER; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYANOSIS; DEATH; DYSPNEA; FLUSHING; GAIT DISORDER; INHALATION TEST; KNOCKOUT MOUSE; LACRIMAL FLUID; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; REFLEX; TRANSGENIC MOUSE; WILD TYPE;

ANIMALIA; MUS MUSCULUS;

EID: 30744454288     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.30.329     Document Type: Article

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