Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis

Journal of the American Chemical Society

Volumn 137, Issue 8, 2015, Pages 3085-3092

  Ruiz Castillo, Paula ^a   Blackmond, Donna G ^b   Buchwald, Stephen L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AROMATIC COMPOUNDS; LIGANDS;

ARYLATIONS; FUNCTIONALIZED; KINETIC ANALYSIS; LIGAND DESIGN; MECHANISTIC ANALYSIS; PRIMARY AMINES; RATIONAL DESIGN; REACTION PROGRESS;

CHEMICAL REACTIONS;

AMINE; HALIDE; LIGAND; PALLADIUM; PHOSPHINE DERIVATIVE; AROMATIC HYDROCARBON;

ARTICLE; ARYLATION; CATALYST; CHEMICAL REACTION KINETICS; CRYSTAL STRUCTURE; HIGH TEMPERATURE; REACTION ANALYSIS; X RAY CRYSTALLOGRAPHY; CATALYSIS; CHEMISTRY; CONFORMATION; DRUG DESIGN; KINETICS; MOLECULAR MODEL; OXIDATION REDUCTION REACTION;

AMINES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HYDROCARBONS, AROMATIC; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OXIDATION-REDUCTION;

EID: 84924303296     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja512903g     Document Type: Article

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