A scalable synthesis of an atropisomeric drug substance via buchwald-hartwig amination and bruylants reactions

Organic Process Research and Development

Volumn 18, Issue 1, 2014, Pages 239-245

  Liu, Yugang ^a   Prashad, Mahavir ^a   Shieh, Wen Chung ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINATION; CHELATION;

ACTIVE PHARMACEUTICAL INGREDIENTS; AMINATION REACTION; AMINO NITRILES; CHEMOKINE RECEPTOR ANTAGONISTS; CHROMATOGRAPHY-FREE SYNTHESIS; DRUG SUBSTANCES; NEW APPROACHES; SCALABLE SYNTHESIS;

SYNTHESIS (CHEMICAL);

EID: 84899819112     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op400250s     Document Type: Article

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