The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer

Molecular and Cellular Proteomics

Volumn 14, Issue 3, 2015, Pages 499-509

  Xu, Junfeng ^a,b   Li, Lihui ^a,b   Yu, Guangyang ^a,b   Ying, Wantao ^c,d   Gao, Qiang ^e   Zhang, Wenjuan ^a,b   Li, Xianyu ^c,d   Ding, Chen ^c,d   Jiang, Yanan ^a,b   Wei, Dongping ^a,b   Duan, Shengzhong ^f   Lei, Qunying ^b   Li, Peng ^f   Shi, Tieliu ^g   Qian, Xiaohong ^c,d   Qin, Jun ^c,d   Jia, Lijun ^a,b  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^b FUDAN UNIVERSITY   (China)

^c BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^d National Engineering Research Center for Protein Drugs   (China)

^e FUDAN UNIVERSITY   (China)

^f INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^g EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CULLIN; CULLIN 2; NEDD8 PROTEIN; PEVONEDISTAT; PROTEIN P21; PROTEIN P27; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CARRIER PROTEIN; CUL2 PROTEIN, HUMAN; NEDD8 PROTEIN, HUMAN; RBX1 PROTEIN, HUMAN; UBIQUITIN;

ARTICLE; CANCER CELL LINE; CELL VIABILITY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; LIVER CANCER; NEDDYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEOMICS; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION; HCT116 CELL LINE; HEPG2 CELL LINE; LIVER TUMOR; MCF 7 CELL LINE; METABOLISM; PROCEDURES; TUMOR CELL LINE; UMBILICAL VEIN ENDOTHELIAL CELL;

CARRIER PROTEINS; CELL LINE, TUMOR; CULLIN PROTEINS; HCT116 CELLS; HEP G2 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIVER NEOPLASMS; MCF-7 CELLS; PROTEOMICS; RHOB GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; UBIQUITINS;

EID: 84924298438     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M114.045211     Document Type: Article

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