-
1
-
-
84908698721
-
Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction
-
Epub 2013/10/03
-
Wang MH, Zhang R, Zhou YQ, Yao HP. Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction. Journal of biomedical research. 2013;27(5):345-56. Epub 2013/10/03.
-
(2013)
Journal of biomedical research
, vol.27
, Issue.5
, pp. 345-356
-
-
Wang, M.H.1
Zhang, R.2
Zhou, Y.Q.3
Yao, H.P.4
-
2
-
-
9944258621
-
The sema domain
-
Epub 2004/12/08
-
Gherardi E, Love CA, Esnouf RM, Jones EY. The sema domain. Current opinion in structural biology. 2004;14(6):669-78. Epub 2004/12/08.
-
(2004)
Current opinion in structural biology
, vol.14
, Issue.6
, pp. 669-678
-
-
Gherardi, E.1
Love, C.A.2
Esnouf, R.M.3
Jones, E.Y.4
-
3
-
-
73449111266
-
Developing c-MET pathway inhibitors for cancer therapy: progress and challenges
-
Epub 2009/12/25
-
Liu X, Newton RC, Scherle PA. Developing c-MET pathway inhibitors for cancer therapy: progress and challenges. Trends in molecular medicine. 2010;16(1):37-45. Epub 2009/12/25.
-
(2010)
Trends in molecular medicine
, vol.16
, Issue.1
, pp. 37-45
-
-
Liu, X.1
Newton, R.C.2
Scherle, P.A.3
-
4
-
-
35148819860
-
Multiple variants of the RON receptor tyrosine kinase: biochemical properties, tumorigenic activities, and potential drug targets
-
Epub 2007/09/25
-
Lu Y, Yao HP, Wang MH. Multiple variants of the RON receptor tyrosine kinase: biochemical properties, tumorigenic activities, and potential drug targets. Cancer letters. 2007;257(2):157-64. Epub 2007/09/25.
-
(2007)
Cancer letters
, vol.257
, Issue.2
, pp. 157-164
-
-
Lu, Y.1
Yao, H.P.2
Wang, M.H.3
-
5
-
-
34848855124
-
The MET receptor tyrosine kinase in invasion and metastasis
-
Epub 2007/07/04
-
Benvenuti S, Comoglio PM. The MET receptor tyrosine kinase in invasion and metastasis. Journal of cellular physiology. 2007;213(2):316-25. Epub 2007/07/04.
-
(2007)
Journal of cellular physiology
, vol.213
, Issue.2
, pp. 316-325
-
-
Benvenuti, S.1
Comoglio, P.M.2
-
6
-
-
84878540077
-
The MET oncogene in glioblastoma stem cells: implications as a diagnostic marker and a therapeutic target
-
Epub 2013/05/23
-
Boccaccio C, Comoglio PM. The MET oncogene in glioblastoma stem cells: implications as a diagnostic marker and a therapeutic target. Cancer research. 2013;73(11):3193-9. Epub 2013/05/23.
-
(2013)
Cancer research
, vol.73
, Issue.11
, pp. 3193-3199
-
-
Boccaccio, C.1
Comoglio, P.M.2
-
7
-
-
18144422402
-
RON, a tyrosine kinase receptor involved in tumor progression and metastasis
-
Epub 2005/04/14
-
Camp ER, Liu W, Fan F, Yang A, Somcio R, Ellis LM. RON, a tyrosine kinase receptor involved in tumor progression and metastasis. Annals of surgical oncology. 2005;12(4):273-81. Epub 2005/04/14.
-
(2005)
Annals of surgical oncology
, vol.12
, Issue.4
, pp. 273-281
-
-
Camp, E.R.1
Liu, W.2
Fan, F.3
Yang, A.4
Somcio, R.5
Ellis, L.M.6
-
8
-
-
33947211838
-
Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target
-
Epub 2007/02/22
-
Camp ER, Yang A, Gray MJ, Fan F, Hamilton SR, Evans DB, et al. Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target. Cancer. 2007;109(6):1030-9. Epub 2007/02/22.
-
(2007)
Cancer
, vol.109
, Issue.6
, pp. 1030-1039
-
-
Camp, E.R.1
Yang, A.2
Gray, M.J.3
Fan, F.4
Hamilton, S.R.5
Evans, D.B.6
-
10
-
-
84894449126
-
The RON receptor tyrosine kinase in pancreatic cancer pathogenesis and its potential implications for future targeted therapies
-
Epub 2014/02/13
-
Kang CM, Babicky ML, Lowy AM. The RON receptor tyrosine kinase in pancreatic cancer pathogenesis and its potential implications for future targeted therapies. Pancreas. 2014;43(2):183-9. Epub 2014/02/13.
-
(2014)
Pancreas
, vol.43
, Issue.2
, pp. 183-189
-
-
Kang, C.M.1
Babicky, M.L.2
Lowy, A.M.3
-
11
-
-
77956039906
-
Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines
-
Epub 2010/08/07
-
McClaine RJ, Marshall AM, Wagh PK, Waltz SE. Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines. Neoplasia. 2010;12(8):650-8. Epub 2010/08/07.
-
(2010)
Neoplasia
, vol.12
, Issue.8
, pp. 650-658
-
-
McClaine, R.J.1
Marshall, A.M.2
Wagh, P.K.3
Waltz, S.E.4
-
12
-
-
83255163981
-
Breast Cancer-Derived Bone Metastasis can be Effectively Reduced through Specific c-MET Inhibitor Tivantinib (ARQ 197) and shRNA c-MET knockdown
-
Epub 2011/10/27
-
Previdi S, Abbadessa G, Dalo F, France DS, Broggini M. Breast Cancer-Derived Bone Metastasis can be Effectively Reduced through Specific c-MET Inhibitor Tivantinib (ARQ 197) and shRNA c-MET knockdown. Molecular cancer therapeutics. 2011. Epub 2011/10/27.
-
(2011)
Molecular cancer therapeutics
-
-
Previdi, S.1
Abbadessa, G.2
Dalo, F.3
France, D.S.4
Broggini, M.5
-
13
-
-
0037386758
-
c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases
-
Epub 2003/04/10
-
Takeuchi H, Bilchik A, Saha S, Turner R, Wiese D, Tanaka M, et al. c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases. Clinical cancer research: an official journal of the American Association for Cancer Research. 2003;9(4):1480-8. Epub 2003/04/10.
-
(2003)
Clinical cancer research: an official journal of the American Association for Cancer Research
, vol.9
, Issue.4
, pp. 1480-1488
-
-
Takeuchi, H.1
Bilchik, A.2
Saha, S.3
Turner, R.4
Wiese, D.5
Tanaka, M.6
-
14
-
-
45549104746
-
Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells
-
Epub 2008/03/04
-
Zhao S, Ammanamanchi S, Brattain M, Cao L, Thangasamy A, Wang J, et al. Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells. The Journal of biological chemistry. 2008;283(17):11293-301. Epub 2008/03/04.
-
(2008)
The Journal of biological chemistry
, vol.283
, Issue.17
, pp. 11293-11301
-
-
Zhao, S.1
Ammanamanchi, S.2
Brattain, M.3
Cao, L.4
Thangasamy, A.5
Wang, J.6
-
15
-
-
81855194258
-
c-Met is a marker of pancreatic cancer stem cells and therapeutic target
-
Epub 2011/09/29
-
Li C, Wu JJ, Hynes M, Dosch J, Sarkar B, Welling TH, et al. c-Met is a marker of pancreatic cancer stem cells and therapeutic target. Gastroenterology. 2011;141(6):2218-27 e5. Epub 2011/09/29.
-
(2011)
Gastroenterology
, vol.141
, Issue.6
, pp. 2218-2227
-
-
Li, C.1
Wu, J.J.2
Hynes, M.3
Dosch, J.4
Sarkar, B.5
Welling, T.H.6
-
16
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Epub 2007/04/28
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. 2007;316(5827):1039-43. Epub 2007/04/28.
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
-
17
-
-
82355191770
-
EGFR and KRAS mutations and altered c-Met gene copy numbers in primary non-small cell lung cancer and associated stage N2 lymph node-metastasis
-
Epub 2011/10/11
-
Han CB, Ma JT, Li F, Zhao JZ, Jing W, Zhou Y, et al. EGFR and KRAS mutations and altered c-Met gene copy numbers in primary non-small cell lung cancer and associated stage N2 lymph node-metastasis. Cancer letters. 2011. Epub 2011/10/11.
-
(2011)
Cancer letters
-
-
Han, C.B.1
Ma, J.T.2
Li, F.3
Zhao, J.Z.4
Jing, W.5
Zhou, Y.6
-
18
-
-
43949111293
-
c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases
-
Epub 2008/04/09
-
Zeng ZS, Weiser MR, Kuntz E, Chen CT, Khan SA, Forslund A, et al. c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases. Cancer letters. 2008;265(2):258-69. Epub 2008/04/09.
-
(2008)
Cancer letters
, vol.265
, Issue.2
, pp. 258-269
-
-
Zeng, Z.S.1
Weiser, M.R.2
Kuntz, E.3
Chen, C.T.4
Khan, S.A.5
Forslund, A.6
-
19
-
-
0035959871
-
Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis
-
Epub 2001/10/11
-
Peace BE, Hughes MJ, Degen SJ, Waltz SE. Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis. Oncogene. 2001;20(43):6142-51. Epub 2001/10/11.
-
(2001)
Oncogene
, vol.20
, Issue.43
, pp. 6142-6151
-
-
Peace, B.E.1
Hughes, M.J.2
Degen, S.J.3
Waltz, S.E.4
-
20
-
-
57149092131
-
Expression and mutational analysis of MET in human solid cancers
-
Epub 2008/08/19
-
Ma PC, Tretiakova MS, MacKinnon AC, Ramnath N, Johnson C, Dietrich S, et al. Expression and mutational analysis of MET in human solid cancers. Genes, chromosomes & cancer. 2008;47(12):1025-37. Epub 2008/08/19.
-
(2008)
Genes, chromosomes & cancer
, vol.47
, Issue.12
, pp. 1025-1037
-
-
Ma, P.C.1
Tretiakova, M.S.2
MacKinnon, A.C.3
Ramnath, N.4
Johnson, C.5
Dietrich, S.6
-
21
-
-
0032514371
-
Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor
-
Epub 1998/08/26
-
Santoro MM, Penengo L, Minetto M, Orecchia S, Cilli M, Gaudino G. Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor. Oncogene. 1998;17(6):741-9. Epub 1998/08/26.
-
(1998)
Oncogene
, vol.17
, Issue.6
, pp. 741-749
-
-
Santoro, M.M.1
Penengo, L.2
Minetto, M.3
Orecchia, S.4
Cilli, M.5
Gaudino, G.6
-
22
-
-
19544389146
-
c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
-
Epub 2005/06/01
-
Christensen JG, Burrows J, Salgia R. c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention. Cancer letters. 2005;225(1):1-26. Epub 2005/06/01.
-
(2005)
Cancer letters
, vol.225
, Issue.1
, pp. 1-26
-
-
Christensen, J.G.1
Burrows, J.2
Salgia, R.3
-
23
-
-
64049101039
-
From concept to reality: the long road to c-Met and RON receptor tyrosine kinase inhibitors for the treatment of cancer
-
Epub 2009/02/10
-
Dussault I, Bellon SF. From concept to reality: the long road to c-Met and RON receptor tyrosine kinase inhibitors for the treatment of cancer. Anti-cancer agents in medicinal chemistry. 2009;9(2):221-9. Epub 2009/02/10.
-
(2009)
Anti-cancer agents in medicinal chemistry
, vol.9
, Issue.2
, pp. 221-229
-
-
Dussault, I.1
Bellon, S.F.2
-
24
-
-
65249122512
-
Novel therapeutic inhibitors of the c-Met signaling pathway in cancer
-
Epub 2009/03/26
-
Eder JP, Vande Woude GF, Boerner SA, LoRusso PM. Novel therapeutic inhibitors of the c-Met signaling pathway in cancer. Clinical cancer research: an official journal of the American Association for Cancer Research. 2009;15(7):2207-14. Epub 2009/03/26.
-
(2009)
Clinical cancer research: an official journal of the American Association for Cancer Research
, vol.15
, Issue.7
, pp. 2207-2214
-
-
Eder, J.P.1
Vande Woude, G.F.2
Boerner, S.A.3
LoRusso, P.M.4
-
25
-
-
79959405665
-
Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer
-
Epub 2011/05/26
-
Katz JD, Jewell JP, Guerin DJ, Lim J, Dinsmore CJ, Deshmukh SV, et al. Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer. Journal of medicinal chemistry. 2011;54(12):4092-108. Epub 2011/05/26.
-
(2011)
Journal of medicinal chemistry
, vol.54
, Issue.12
, pp. 4092-4108
-
-
Katz, J.D.1
Jewell, J.P.2
Guerin, D.J.3
Lim, J.4
Dinsmore, C.J.5
Deshmukh, S.V.6
-
26
-
-
77954152767
-
Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells
-
Epub 2010/07/03
-
Li Z, Yao H, Guin S, Padhye SS, Zhou YQ, Wang MH. Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells. International journal of oncology. 2010;37(2):473-82. Epub 2010/07/03.
-
(2010)
International journal of oncology
, vol.37
, Issue.2
, pp. 473-482
-
-
Li, Z.1
Yao, H.2
Guin, S.3
Padhye, S.S.4
Zhou, Y.Q.5
Wang, M.H.6
-
27
-
-
77956379695
-
Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy
-
Epub 2010/08/10
-
Wang MH, Padhye SS, Guin S, Ma Q, Zhou YQ. Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy. Acta pharmacologica Sinica. 2010;31(9):1181-8. Epub 2010/08/10.
-
(2010)
Acta pharmacologica Sinica
, vol.31
, Issue.9
, pp. 1181-1188
-
-
Wang, M.H.1
Padhye, S.S.2
Guin, S.3
Ma, Q.4
Zhou, Y.Q.5
-
29
-
-
79952222098
-
Ron kinase transphosphorylation sustains MET oncogene addiction
-
Epub 2011/01/08
-
Benvenuti S, Lazzari L, Arnesano A, Li Chiavi G, Gentile A, Comoglio PM. Ron kinase transphosphorylation sustains MET oncogene addiction. Cancer research. 2011;71(5):1945-55. Epub 2011/01/08.
-
(2011)
Cancer research
, vol.71
, Issue.5
, pp. 1945-1955
-
-
Benvenuti, S.1
Lazzari, L.2
Arnesano, A.3
Li Chiavi, G.4
Gentile, A.5
Comoglio, P.M.6
-
30
-
-
84881089423
-
MSP-RON signalling in cancer: pathogenesis and therapeutic potential
-
Epub 2013/06/26
-
Yao HP, Zhou YQ, Zhang R, Wang MH. MSP-RON signalling in cancer: pathogenesis and therapeutic potential. Nature reviews Cancer. 2013;13(7):466-81. Epub 2013/06/26.
-
(2013)
Nature reviews Cancer
, vol.13
, Issue.7
, pp. 466-481
-
-
Yao, H.P.1
Zhou, Y.Q.2
Zhang, R.3
Wang, M.H.4
-
31
-
-
80052714163
-
Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET
-
Epub 2011/07/26
-
Chaudhuri A, Xie MH, Yang B, Mahapatra K, Liu J, Marsters S, et al. Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET. The Journal of biological chemistry. 2011;286(37):32762-74. Epub 2011/07/26.
-
(2011)
The Journal of biological chemistry
, vol.286
, Issue.37
, pp. 32762-32774
-
-
Chaudhuri, A.1
Xie, M.H.2
Yang, B.3
Mahapatra, K.4
Liu, J.5
Marsters, S.6
-
32
-
-
0028123022
-
RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP
-
Epub 1994/08/01
-
Gaudino G, Follenzi A, Naldini L, Collesi C, Santoro M, Gallo KA, et al. RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. The EMBO journal. 1994;13(15):3524-32. Epub 1994/08/01.
-
(1994)
The EMBO journal
, vol.13
, Issue.15
, pp. 3524-3532
-
-
Gaudino, G.1
Follenzi, A.2
Naldini, L.3
Collesi, C.4
Santoro, M.5
Gallo, K.A.6
-
33
-
-
84905001923
-
HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer
-
Epub 2014/06/24
-
Mariani M, McHugh M, Petrillo M, Sieber S, He S, Andreoli M, et al. HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer. Oncotarget. 2014;5(13):4855-67. Epub 2014/06/24.
-
(2014)
Oncotarget
, vol.5
, Issue.13
, pp. 4855-4867
-
-
Mariani, M.1
McHugh, M.2
Petrillo, M.3
Sieber, S.4
He, S.5
Andreoli, M.6
-
34
-
-
0036006814
-
Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition
-
Epub 2001/12/26
-
Maulik G, Shrikhande A, Kijima T, Ma PC, Morrison PT, Salgia R. Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition. Cytokine & growth factor reviews. 2002;13(1):41-59. Epub 2001/12/26.
-
(2002)
Cytokine & growth factor reviews
, vol.13
, Issue.1
, pp. 41-59
-
-
Maulik, G.1
Shrikhande, A.2
Kijima, T.3
Ma, P.C.4
Morrison, P.T.5
Salgia, R.6
-
35
-
-
84896055470
-
Analysis of HGF, MACC1, C-met and apoptosis-related genes in cervical carcinoma mice
-
Epub 2014/01/29
-
Chen XP, Ren XP, Lan JY, Chen YG, Shen ZJ. Analysis of HGF, MACC1, C-met and apoptosis-related genes in cervical carcinoma mice. Molecular biology reports. 2014;41(3):1247-56. Epub 2014/01/29.
-
(2014)
Molecular biology reports
, vol.41
, Issue.3
, pp. 1247-1256
-
-
Chen, X.P.1
Ren, X.P.2
Lan, J.Y.3
Chen, Y.G.4
Shen, Z.J.5
-
36
-
-
0021285134
-
Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
-
Epub 1984/08/16
-
Nakamura T, Nawa K, Ichihara A. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochemical and biophysical research communications. 1984;122(3):1450-9. Epub 1984/08/16.
-
(1984)
Biochemical and biophysical research communications
, vol.122
, Issue.3
, pp. 1450-1459
-
-
Nakamura, T.1
Nawa, K.2
Ichihara, A.3
-
37
-
-
0025734655
-
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET
-
Epub 1991/04/01
-
Naldini L, Vigna E, Narsimhan RP, Gaudino G, Zarnegar R, Michalopoulos GK, et al. Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene. 1991;6(4):501-4. Epub 1991/04/01.
-
(1991)
Oncogene
, vol.6
, Issue.4
, pp. 501-504
-
-
Naldini, L.1
Vigna, E.2
Narsimhan, R.P.3
Gaudino, G.4
Zarnegar, R.5
Michalopoulos, G.K.6
-
38
-
-
77955102398
-
The discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicine
-
Epub 2010/06/17
-
Nakamura T, Mizuno S. The discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicine. Proceedings of the Japan Academy Series B, Physical and biological sciences. 2010;86(6):588-610. Epub 2010/06/17.
-
(2010)
Proceedings of the Japan Academy Series B, Physical and biological sciences
, vol.86
, Issue.6
, pp. 588-610
-
-
Nakamura, T.1
Mizuno, S.2
-
39
-
-
0028567137
-
Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP)
-
Epub 1994/12/01
-
Donate LE, Gherardi E, Srinivasan N, Sowdhamini R, Aparicio S, Blundell TL. Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP). Protein science: a publication of the Protein Society. 1994;3(12):2378-94. Epub 1994/12/01.
-
(1994)
Protein science: a publication of the Protein Society
, vol.3
, Issue.12
, pp. 2378-2394
-
-
Donate, L.E.1
Gherardi, E.2
Srinivasan, N.3
Sowdhamini, R.4
Aparicio, S.5
Blundell, T.L.6
-
40
-
-
39149083413
-
Prognostic value of MET, RON and histoprognostic factors for urothelial carcinoma in the upper urinary tract
-
discussion 72. Epub 2008/01/29
-
Comperat E, Roupret M, Chartier-Kastler E, Bitker MO, Richard F, Camparo P, et al. Prognostic value of MET, RON and histoprognostic factors for urothelial carcinoma in the upper urinary tract. The Journal of urology. 2008;179(3):868-72; discussion 72. Epub 2008/01/29.
-
(2008)
The Journal of urology
, vol.179
, Issue.3
, pp. 868-872
-
-
Comperat, E.1
Roupret, M.2
Chartier-Kastler, E.3
Bitker, M.O.4
Richard, F.5
Camparo, P.6
-
41
-
-
20344392876
-
Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder
-
Epub 2005/05/05
-
Cheng HL, Liu HS, Lin YJ, Chen HH, Hsu PY, Chang TY, et al. Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder. British journal of cancer. 2005;92(10):1906-14. Epub 2005/05/05.
-
(2005)
British journal of cancer
, vol.92
, Issue.10
, pp. 1906-1914
-
-
Cheng, H.L.1
Liu, H.S.2
Lin, Y.J.3
Chen, H.H.4
Hsu, P.Y.5
Chang, T.Y.6
-
42
-
-
0042063642
-
The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness
-
Epub 2003/08/14
-
Maggiora P, Lorenzato A, Fracchioli S, Costa B, Castagnaro M, Arisio R, et al. The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness. Experimental cell research. 2003;288(2):382-9. Epub 2003/08/14.
-
(2003)
Experimental cell research
, vol.288
, Issue.2
, pp. 382-389
-
-
Maggiora, P.1
Lorenzato, A.2
Fracchioli, S.3
Costa, B.4
Castagnaro, M.5
Arisio, R.6
-
43
-
-
0034702178
-
Cross-talk between the proto-oncogenes Met and Ron
-
Epub 2000/06/29
-
Follenzi A, Bakovic S, Gual P, Stella MC, Longati P, Comoglio PM. Cross-talk between the proto-oncogenes Met and Ron. Oncogene. 2000;19(27):3041-9. Epub 2000/06/29.
-
(2000)
Oncogene
, vol.19
, Issue.27
, pp. 3041-3049
-
-
Follenzi, A.1
Bakovic, S.2
Gual, P.3
Stella, M.C.4
Longati, P.5
Comoglio, P.M.6
-
44
-
-
84887000382
-
Knockdown of RON receptor kinase delays but does not prevent tumor progression while enhancing HGF/MET signaling in pancreatic cancer cell lines
-
Epub 2013/10/09
-
Zhao S, Cao L, Freeman JW. Knockdown of RON receptor kinase delays but does not prevent tumor progression while enhancing HGF/MET signaling in pancreatic cancer cell lines. Oncogenesis. 2013;2:e76. Epub 2013/10/09.
-
(2013)
Oncogenesis
, vol.2
-
-
Zhao, S.1
Cao, L.2
Freeman, J.W.3
-
45
-
-
0029997180
-
Constitutive activation of the RON gene promotes invasive growth but not transformation
-
Epub 1996/12/01
-
Santoro MM, Collesi C, Grisendi S, Gaudino G, Comoglio PM. Constitutive activation of the RON gene promotes invasive growth but not transformation. Molecular and cellular biology. 1996;16(12):7072-83. Epub 1996/12/01.
-
(1996)
Molecular and cellular biology
, vol.16
, Issue.12
, pp. 7072-7083
-
-
Santoro, M.M.1
Collesi, C.2
Grisendi, S.3
Gaudino, G.4
Comoglio, P.M.5
-
46
-
-
76249113994
-
Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers
-
Epub 2010/01/28
-
Logan-Collins J, Thomas RM, Yu P, Jaquish D, Mose E, French R, et al. Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers. Cancer research. 2010;70(3):1130-40. Epub 2010/01/28.
-
(2010)
Cancer research
, vol.70
, Issue.3
, pp. 1130-1140
-
-
Logan-Collins, J.1
Thomas, R.M.2
Yu, P.3
Jaquish, D.4
Mose, E.5
French, R.6
-
47
-
-
79961197555
-
IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration
-
Epub 2011/05/14
-
Jaquish DV, Yu PT, Shields DJ, French RP, Maruyama KP, Niessen S, et al. IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration. Carcinogenesis. 2011;32(8):1151-6. Epub 2011/05/14.
-
(2011)
Carcinogenesis
, vol.32
, Issue.8
, pp. 1151-1156
-
-
Jaquish, D.V.1
Yu, P.T.2
Shields, D.J.3
French, R.P.4
Maruyama, K.P.5
Niessen, S.6
-
48
-
-
84881087515
-
Ron tyrosine kinase receptor synergises with EGFR to confer adverse features in head and neck squamous cell carcinoma
-
Epub 2013/06/27
-
Keller J, Nimnual AS, Shroyer KR, Joy C, Ischenko I, Chandler CS, et al. Ron tyrosine kinase receptor synergises with EGFR to confer adverse features in head and neck squamous cell carcinoma. British journal of cancer. 2013;109(2):482-92. Epub 2013/06/27.
-
(2013)
British journal of cancer
, vol.109
, Issue.2
, pp. 482-492
-
-
Keller, J.1
Nimnual, A.S.2
Shroyer, K.R.3
Joy, C.4
Ischenko, I.5
Chandler, C.S.6
-
49
-
-
80051800007
-
HGF-independent potentiation of EGFR action by c-Met
-
Epub 2011/03/23
-
Dulak AM, Gubish CT, Stabile LP, Henry C, Siegfried JM. HGF-independent potentiation of EGFR action by c-Met. Oncogene. 2011;30(33):3625-35. Epub 2011/03/23.
-
(2011)
Oncogene
, vol.30
, Issue.33
, pp. 3625-3635
-
-
Dulak, A.M.1
Gubish, C.T.2
Stabile, L.P.3
Henry, C.4
Siegfried, J.M.5
-
50
-
-
69149089019
-
Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer
-
Epub 2009/07/02
-
Graveel CR, DeGroot JD, Su Y, Koeman J, Dykema K, Leung S, et al. Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(31):12909-14. Epub 2009/07/02.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.31
, pp. 12909-12914
-
-
Graveel, C.R.1
DeGroot, J.D.2
Su, Y.3
Koeman, J.4
Dykema, K.5
Leung, S.6
-
51
-
-
84891864612
-
Epithelial-mesenchymal transition and its regulators are major targets of triple-negative breast cancer
-
Epub 2013/10/25
-
Al Moustafa AE. Epithelial-mesenchymal transition and its regulators are major targets of triple-negative breast cancer. Cell adhesion & migration. 2013;7(5):424-5. Epub 2013/10/25.
-
(2013)
Cell adhesion & migration
, vol.7
, Issue.5
, pp. 424-425
-
-
Al Moustafa, A.E.1
-
52
-
-
41949087400
-
Regulation of RON tyrosine kinase-mediated invasion of breast cancer cells
-
Epub 2008/01/01
-
Thangasamy A, Rogge J, Ammanamanchi S. Regulation of RON tyrosine kinase-mediated invasion of breast cancer cells. The Journal of biological chemistry. 2008;283(9):5335-43. Epub 2008/01/01.
-
(2008)
The Journal of biological chemistry
, vol.283
, Issue.9
, pp. 5335-5343
-
-
Thangasamy, A.1
Rogge, J.2
Ammanamanchi, S.3
-
53
-
-
77958102573
-
CD44-independent activation of the Met signaling pathway by HGF and InlB
-
Epub 2010/07/31
-
Dortet L, Veiga E, Bonazzi M, Cossart P. CD44-independent activation of the Met signaling pathway by HGF and InlB. Microbes and infection/Institut Pasteur. 2010;12(12-13):919-27. Epub 2010/07/31.
-
(2010)
Microbes and infection/Institut Pasteur
, vol.12
, Issue.12-13
, pp. 919-927
-
-
Dortet, L.1
Veiga, E.2
Bonazzi, M.3
Cossart, P.4
-
54
-
-
0036896923
-
CD44 is required for two consecutive steps in HGF/c-Met signaling
-
Epub 2002/12/05
-
Orian-Rousseau V, Chen L, Sleeman JP, Herrlich P, Ponta H. CD44 is required for two consecutive steps in HGF/c-Met signaling. Genes & development. 2002;16(23):3074-86. Epub 2002/12/05.
-
(2002)
Genes & development
, vol.16
, Issue.23
, pp. 3074-3086
-
-
Orian-Rousseau, V.1
Chen, L.2
Sleeman, J.P.3
Herrlich, P.4
Ponta, H.5
-
55
-
-
34248224915
-
A novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infection
-
Epub 2007/03/14
-
Ni S, Zhao C, Feng GS, Paulson RF, Correll PH. A novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infection. Molecular and cellular biology. 2007;27(10):3708-15. Epub 2007/03/14.
-
(2007)
Molecular and cellular biology
, vol.27
, Issue.10
, pp. 3708-3715
-
-
Ni, S.1
Zhao, C.2
Feng, G.S.3
Paulson, R.F.4
Correll, P.H.5
-
56
-
-
84886096078
-
Inhibition of c-Met promoted apoptosis, autophagy and loss of the mitochondrial transmembrane potential in oridonin-induced A549 lung cancer cells
-
Epub 2013/10/10
-
Liu Y, Liu JH, Chai K, Tashiro S, Onodera S, Ikejima T. Inhibition of c-Met promoted apoptosis, autophagy and loss of the mitochondrial transmembrane potential in oridonin-induced A549 lung cancer cells. The Journal of pharmacy and pharmacology. 2013;65(11):1622-42. Epub 2013/10/10.
-
(2013)
The Journal of pharmacy and pharmacology
, vol.65
, Issue.11
, pp. 1622-1642
-
-
Liu, Y.1
Liu, J.H.2
Chai, K.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
57
-
-
0026485121
-
Hepatocyte growth factor is a synergistic factor for the growth of hematopoietic progenitor cells
-
Epub 1992/11/15
-
Kmiecik TE, Keller JR, Rosen E, Vande Woude GF. Hepatocyte growth factor is a synergistic factor for the growth of hematopoietic progenitor cells. Blood. 1992;80(10):2454-7. Epub 1992/11/15.
-
(1992)
Blood
, vol.80
, Issue.10
, pp. 2454-2457
-
-
Kmiecik, T.E.1
Keller, J.R.2
Rosen, E.3
Vande Woude, G.F.4
-
58
-
-
84864863728
-
MET signaling regulates glioblastoma stem cells
-
Epub 2012/05/24
-
Joo KM, Jin J, Kim E, Ho Kim K, Kim Y, Gu Kang B, et al. MET signaling regulates glioblastoma stem cells. Cancer research. 2012;72(15):3828-38. Epub 2012/05/24.
-
(2012)
Cancer research
, vol.72
, Issue.15
, pp. 3828-3838
-
-
Joo, K.M.1
Jin, J.2
Kim, E.3
Ho Kim, K.4
Kim, Y.5
Gu Kang, B.6
-
59
-
-
79959971880
-
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
-
Epub 2011/06/02
-
Li Y, Li A, Glas M, Lal B, Ying M, Sang Y, et al. c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proceedings of the National Academy of Sciences of the United States of America. 2011;108(24):9951-6. Epub 2011/06/02.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.24
, pp. 9951-9956
-
-
Li, Y.1
Li, A.2
Glas, M.3
Lal, B.4
Ying, M.5
Sang, Y.6
-
60
-
-
84875605329
-
Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor
-
Epub 2013/01/17
-
Nishida S, Hirohashi Y, Torigoe T, Inoue R, Kitamura H, Tanaka T, et al. Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor. Cancer science. 2013;104(4):431-6. Epub 2013/01/17.
-
(2013)
Cancer science
, vol.104
, Issue.4
, pp. 431-436
-
-
Nishida, S.1
Hirohashi, Y.2
Torigoe, T.3
Inoue, R.4
Kitamura, H.5
Tanaka, T.6
-
62
-
-
34547558390
-
Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion
-
Epub 2007/08/02
-
Ma PC, Tretiakova MS, Nallasura V, Jagadeeswaran R, Husain AN, Salgia R. Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion. British journal of cancer. 2007;97(3):368-77. Epub 2007/08/02.
-
(2007)
British journal of cancer
, vol.97
, Issue.3
, pp. 368-377
-
-
Ma, P.C.1
Tretiakova, M.S.2
Nallasura, V.3
Jagadeeswaran, R.4
Husain, A.N.5
Salgia, R.6
-
63
-
-
62049085386
-
Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and-7 and E-cadherin
-
Epub 2009/01/06
-
Miyata Y, Sagara Y, Kanda S, Hayashi T, Kanetake H. Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and-7 and E-cadherin. Human pathology. 2009;40(4):496-504. Epub 2009/01/06.
-
(2009)
Human pathology
, vol.40
, Issue.4
, pp. 496-504
-
-
Miyata, Y.1
Sagara, Y.2
Kanda, S.3
Hayashi, T.4
Kanetake, H.5
-
64
-
-
0033966745
-
Expression of hepatocyte growth factor (HGF)/scatter factor and its receptor c-MET correlates with poor prognosis in synovial sarcoma
-
Epub 2000/02/24
-
Oda Y, Sakamoto A, Saito T, Kinukawa N, Iwamoto Y, Tsuneyoshi M. Expression of hepatocyte growth factor (HGF)/scatter factor and its receptor c-MET correlates with poor prognosis in synovial sarcoma. Human pathology. 2000;31(2):185-92. Epub 2000/02/24.
-
(2000)
Human pathology
, vol.31
, Issue.2
, pp. 185-192
-
-
Oda, Y.1
Sakamoto, A.2
Saito, T.3
Kinukawa, N.4
Iwamoto, Y.5
Tsuneyoshi, M.6
-
65
-
-
84893845694
-
c-Met expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation
-
Epub 2014/02/14
-
Baschnagel AM, Williams L, Hanna A, Chen PY, Krauss DJ, Pruetz BL, et al. c-Met expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation. International journal of radiation oncology, biology, physics. 2014;88(3):701-7. Epub 2014/02/14.
-
(2014)
International journal of radiation oncology, biology, physics
, vol.88
, Issue.3
, pp. 701-707
-
-
Baschnagel, A.M.1
Williams, L.2
Hanna, A.3
Chen, P.Y.4
Krauss, D.J.5
Pruetz, B.L.6
-
66
-
-
84887414585
-
Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy
-
Epub 2013/10/30
-
Xie Q, Su Y, Dykema K, Johnson J, Koeman J, De Giorgi V, et al. Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy. Genes & cancer. 2013;4(7-8):247-60. Epub 2013/10/30.
-
(2013)
Genes & cancer
, vol.4
, Issue.7-8
, pp. 247-260
-
-
Xie, Q.1
Su, Y.2
Dykema, K.3
Johnson, J.4
Koeman, J.5
De Giorgi, V.6
-
67
-
-
84899030304
-
MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit
-
Epub 2014/04/20
-
Jardim DL, de Melo Gagliato D, Falchook GS, Janku F, Zinner R, Wheler JJ, et al. MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit. Oncotarget. 2014;5(7):1837-45. Epub 2014/04/20.
-
(2014)
Oncotarget
, vol.5
, Issue.7
, pp. 1837-1845
-
-
Jardim, D.L.1
de Melo Gagliato, D.2
Falchook, G.S.3
Janku, F.4
Zinner, R.5
Wheler, J.J.6
-
68
-
-
77950285105
-
The RON tyrosine kinase receptor regulates vascular endothelial growth factor production in pancreatic cancer cells
-
Epub 2010/04/02
-
Thomas RM, Jaquish DV, French RP, Lowy AM. The RON tyrosine kinase receptor regulates vascular endothelial growth factor production in pancreatic cancer cells. Pancreas. 2010;39(3):301-7. Epub 2010/04/02.
-
(2010)
Pancreas
, vol.39
, Issue.3
, pp. 301-307
-
-
Thomas, R.M.1
Jaquish, D.V.2
French, R.P.3
Lowy, A.M.4
-
69
-
-
82955173078
-
Sustained Expression of the RON Receptor Tyrosine Kinase by Pancreatic Cancer Stem Cells as a Potential Targeting Moiety for Antibody-Directed Chemotherapeutics
-
Epub 2011/10/22
-
Padhye SS, Guin S, Yao HP, Zhou YQ, Zhang R, Wang MH. Sustained Expression of the RON Receptor Tyrosine Kinase by Pancreatic Cancer Stem Cells as a Potential Targeting Moiety for Antibody-Directed Chemotherapeutics. Molecular pharmaceutics. 2011. Epub 2011/10/22.
-
(2011)
Molecular pharmaceutics
-
-
Padhye, S.S.1
Guin, S.2
Yao, H.P.3
Zhou, Y.Q.4
Zhang, R.5
Wang, M.H.6
-
70
-
-
84898922599
-
The Met receptor tyrosine kinase: A key player in oncogenesis and drug resistance
-
Epub 2014/01/05
-
Maroun CR, Rowlands T. The Met receptor tyrosine kinase: A key player in oncogenesis and drug resistance. Pharmacology & therapeutics. 2014;142(3):316-38. Epub 2014/01/05.
-
(2014)
Pharmacology & therapeutics
, vol.142
, Issue.3
, pp. 316-338
-
-
Maroun, C.R.1
Rowlands, T.2
-
71
-
-
79952819549
-
MET Inhibition Results in DNA Breaks and Synergistically Sensitizes Tumor Cells to DNA-Damaging Agents Potentially by Breaching a Damage-Induced Checkpoint Arrest
-
Epub 2011/07/23
-
Medova M, Aebersold DM, Blank-Liss W, Streit B, Medo M, Aebi S, et al. MET Inhibition Results in DNA Breaks and Synergistically Sensitizes Tumor Cells to DNA-Damaging Agents Potentially by Breaching a Damage-Induced Checkpoint Arrest. Genes & cancer. 2010;1(10):1053-62. Epub 2011/07/23.
-
(2010)
Genes & cancer
, vol.1
, Issue.10
, pp. 1053-1062
-
-
Medova, M.1
Aebersold, D.M.2
Blank-Liss, W.3
Streit, B.4
Medo, M.5
Aebi, S.6
-
72
-
-
84874037058
-
Tivantinib: a new promising mesenchymal-epithelial transition factor inhibitor in the treatment of hepatocellular carcinoma
-
Epub 2013/02/19
-
Rimassa L, Personeni N, Simonelli M, Santoro A. Tivantinib: a new promising mesenchymal-epithelial transition factor inhibitor in the treatment of hepatocellular carcinoma. Future Oncol. 2013;9(2):153-65. Epub 2013/02/19.
-
(2013)
Future Oncol
, vol.9
, Issue.2
, pp. 153-165
-
-
Rimassa, L.1
Personeni, N.2
Simonelli, M.3
Santoro, A.4
-
73
-
-
84871721240
-
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study
-
Epub 2012/11/28
-
Santoro A, Rimassa L, Borbath I, Daniele B, Salvagni S, Van Laethem JL, et al. Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study. The lancet oncology. 2013;14(1):55-63. Epub 2012/11/28.
-
(2013)
The lancet oncology
, vol.14
, Issue.1
, pp. 55-63
-
-
Santoro, A.1
Rimassa, L.2
Borbath, I.3
Daniele, B.4
Salvagni, S.5
Van Laethem, J.L.6
-
74
-
-
84891370054
-
A survey of c-MET expression and amplification in 287 patients with hepatocellular carcinoma
-
Epub 2013/11/14
-
Lee SJ, Lee J, Sohn I, Mao M, Kai W, Park CK, et al. A survey of c-MET expression and amplification in 287 patients with hepatocellular carcinoma. Anticancer research. 2013;33(11):5179-86. Epub 2013/11/14.
-
(2013)
Anticancer research
, vol.33
, Issue.11
, pp. 5179-5186
-
-
Lee, S.J.1
Lee, J.2
Sohn, I.3
Mao, M.4
Kai, W.5
Park, C.K.6
-
75
-
-
63849163410
-
Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients
-
Epub 2009/03/04
-
Cappuzzo F, Marchetti A, Skokan M, Rossi E, Gajapathy S, Felicioni L, et al. Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2009;27(10):1667-74. Epub 2009/03/04.
-
(2009)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.27
, Issue.10
, pp. 1667-1674
-
-
Cappuzzo, F.1
Marchetti, A.2
Skokan, M.3
Rossi, E.4
Gajapathy, S.5
Felicioni, L.6
-
76
-
-
84891333707
-
Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors
-
Epub 2014/01/05
-
Nanjo S, Yamada T, Nishihara H, Takeuchi S, Sano T, Nakagawa T, et al. Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors. PloS one. 2013;8(12):e84700. Epub 2014/01/05.
-
(2013)
PloS one
, vol.8
, Issue.12
-
-
Nanjo, S.1
Yamada, T.2
Nishihara, H.3
Takeuchi, S.4
Sano, T.5
Nakagawa, T.6
-
77
-
-
77954586493
-
Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis
-
Epub 2010/05/22
-
Benedettini E, Sholl LM, Peyton M, Reilly J, Ware C, Davis L, et al. Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis. The American journal of pathology. 2010;177(1):415-23. Epub 2010/05/22.
-
(2010)
The American journal of pathology
, vol.177
, Issue.1
, pp. 415-423
-
-
Benedettini, E.1
Sholl, L.M.2
Peyton, M.3
Reilly, J.4
Ware, C.5
Davis, L.6
-
78
-
-
80051974548
-
Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer
-
Epub 2011/07/20
-
Sequist LV, von Pawel J, Garmey EG, Akerley WL, Brugger W, Ferrari D, et al. Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2011;29(24):3307-15. Epub 2011/07/20.
-
(2011)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.29
, Issue.24
, pp. 3307-3315
-
-
Sequist, L.V.1
von Pawel, J.2
Garmey, E.G.3
Akerley, W.L.4
Brugger, W.5
Ferrari, D.6
-
79
-
-
84865506979
-
Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer
-
Epub 2012/03/24
-
Scagliotti GV, Novello S, Schiller JH, Hirsh V, Sequist LV, Soria JC, et al. Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer. Clinical lung cancer. 2012;13(5):391-5. Epub 2012/03/24.
-
(2012)
Clinical lung cancer
, vol.13
, Issue.5
, pp. 391-395
-
-
Scagliotti, G.V.1
Novello, S.2
Schiller, J.H.3
Hirsh, V.4
Sequist, L.V.5
Soria, J.C.6
-
80
-
-
84872548337
-
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma
-
Epub 2012/12/06
-
Choueiri TK, Vaishampayan U, Rosenberg JE, Logan TF, Harzstark AL, Bukowski RM, et al. Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2013;31(2):181-6. Epub 2012/12/06.
-
(2013)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.31
, Issue.2
, pp. 181-186
-
-
Choueiri, T.K.1
Vaishampayan, U.2
Rosenberg, J.E.3
Logan, T.F.4
Harzstark, A.L.5
Bukowski, R.M.6
-
81
-
-
84910071856
-
Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer
-
Epub 2014/09/07
-
Yan HH, Jung KH, Son MK, Fang Z, Kim SJ, Ryu YL, et al. Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer. Oncotarget. 2014;5(19):9150-68. Epub 2014/09/07.
-
(2014)
Oncotarget
, vol.5
, Issue.19
, pp. 9150-9168
-
-
Yan, H.H.1
Jung, K.H.2
Son, M.K.3
Fang, Z.4
Kim, S.J.5
Ryu, Y.L.6
-
82
-
-
38049150665
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
-
Epub 2007/12/21
-
Bean J, Brennan C, Shih JY, Riely G, Viale A, Wang L, et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proceedings of the National Academy of Sciences of the United States of America. 2007;104(52):20932-7. Epub 2007/12/21.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.52
, pp. 20932-20937
-
-
Bean, J.1
Brennan, C.2
Shih, J.Y.3
Riely, G.4
Viale, A.5
Wang, L.6
-
83
-
-
84880785380
-
Ron knockdown and Ron monoclonal antibody IMC-RON8 sensitize pancreatic cancer to histone deacetylase inhibitors (HDACi)
-
Epub 2013/08/08
-
Zou Y, Howell GM, Humphrey LE, Wang J, Brattain MG. Ron knockdown and Ron monoclonal antibody IMC-RON8 sensitize pancreatic cancer to histone deacetylase inhibitors (HDACi). PloS one. 2013;8(7):e69992. Epub 2013/08/08.
-
(2013)
PloS one
, vol.8
, Issue.7
-
-
Zou, Y.1
Howell, G.M.2
Humphrey, L.E.3
Wang, J.4
Brattain, M.G.5
-
84
-
-
84883793323
-
RON confers lapatinib resistance in HER2-positive breast cancer cells
-
Epub 2013/07/03
-
Wang Q, Quan H, Zhao J, Xie C, Wang L, Lou L. RON confers lapatinib resistance in HER2-positive breast cancer cells. Cancer letters. 2013;340(1):43-50. Epub 2013/07/03.
-
(2013)
Cancer letters
, vol.340
, Issue.1
, pp. 43-50
-
-
Wang, Q.1
Quan, H.2
Zhao, J.3
Xie, C.4
Wang, L.5
Lou, L.6
-
85
-
-
84873669382
-
HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells
-
Epub 2012/12/13
-
Matsumura A, Kubota T, Taiyoh H, Fujiwara H, Okamoto K, Ichikawa D, et al. HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells. International journal of oncology. 2013;42(2):535-42. Epub 2012/12/13.
-
(2013)
International journal of oncology
, vol.42
, Issue.2
, pp. 535-542
-
-
Matsumura, A.1
Kubota, T.2
Taiyoh, H.3
Fujiwara, H.4
Okamoto, K.5
Ichikawa, D.6
-
86
-
-
84873928134
-
Axitinib for the treatment of patients with advanced metastatic renal cell carcinoma (mRCC) after failure of prior systemic treatment
-
Epub 2012/07/13
-
Grunwald V, Merseburger AS. Axitinib for the treatment of patients with advanced metastatic renal cell carcinoma (mRCC) after failure of prior systemic treatment. OncoTargets and therapy. 2012;5:111-7. Epub 2012/07/13.
-
(2012)
OncoTargets and therapy
, vol.5
, pp. 111-117
-
-
Grunwald, V.1
Merseburger, A.S.2
-
87
-
-
84898408415
-
Safety and efficacy of addition of VEGFR and EGFR-family oral small-molecule tyrosine kinase inhibitors to cytotoxic chemotherapy in solid cancers: A systematic review and meta-analysis of randomized controlled trials
-
Epub 2014/03/19
-
Funakoshi T, Latif A, Galsky MD. Safety and efficacy of addition of VEGFR and EGFR-family oral small-molecule tyrosine kinase inhibitors to cytotoxic chemotherapy in solid cancers: A systematic review and meta-analysis of randomized controlled trials. Cancer treatment reviews. 2014;40(5):636-47. Epub 2014/03/19.
-
(2014)
Cancer treatment reviews
, vol.40
, Issue.5
, pp. 636-647
-
-
Funakoshi, T.1
Latif, A.2
Galsky, M.D.3
-
88
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Epub 2009/03/03
-
Ebos JM, Lee CR, Cruz-Munoz W, Bjarnason GA, Christensen JG, Kerbel RS. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer cell. 2009;15(3):232-9. Epub 2009/03/03.
-
(2009)
Cancer cell
, vol.15
, Issue.3
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
89
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Epub 2009/03/03
-
Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Vinals F, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer cell. 2009;15(3):220-31. Epub 2009/03/03.
-
(2009)
Cancer cell
, vol.15
, Issue.3
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
-
90
-
-
84863704553
-
Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors
-
Epub 2012/05/16
-
Sennino B, Ishiguro-Oonuma T, Wei Y, Naylor RM, Williamson CW, Bhagwandin V, et al. Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors. Cancer discovery. 2012;2(3):270-87. Epub 2012/05/16.
-
(2012)
Cancer discovery
, vol.2
, Issue.3
, pp. 270-287
-
-
Sennino, B.1
Ishiguro-Oonuma, T.2
Wei, Y.3
Naylor, R.M.4
Williamson, C.W.5
Bhagwandin, V.6
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