Expression of hepatocyte growth factor (HGF)/scatter factor and its receptor c-MET correlates with poor prognosis in synovial sarcoma

Human Pathology

Volumn 31, Issue 2, 2000, Pages 185-192

  Oda, Yoshinao ^a   Sakamoto, Akio ^a   Saito, Tsuyoshi ^a   Kinukawa, Naoko ^a   Iwamoto, Yukihide ^a   Tsuneyoshi, Masazumi ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

c MET; HGF; RT PCR; Synovial sarcoma; SYT SSX fusion gene

Indexed keywords

MESSENGER RNA; SCATTER FACTOR; SCATTER FACTOR RECEPTOR;

CANCER STAGING; CANCER SURVIVAL; CARCINOGENESIS; CONFERENCE PAPER; FROZEN SECTION; FUSION GENE; GENDER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LABELING INDEX; MAST CELL; PARACRINE SIGNALING; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHABDOID TUMOR; RNA ANALYSIS; SYNOVIAL SARCOMA; TUMOR VOLUME;

EID: 0033966745     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(00)80218-X     Document Type: Conference Paper

References (36)

1. Nakamura T Nishizawa T Hagiya M Molecular cloning and expression of human hepatocyte growth factor Nature 342 1989 440 443
2. Weidner KM Arakaki N Hartmann G Evidence for the identity of human scatter factor and hepatocyte growth factor Proc Natl Acad Sci U S A 88 1991 7001 7005
3. Schmidt C Bladt F Goedecke S Scatter factor/hepatocyte growth factor is essential for liver development Nature 373 1995 699 702
4. Takayama H LaRochelle WJ Anver M Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development Proc Natl Acad Sci U S A 93 1996 5866 5871
5. Comoglio PM Goldberg ID Rosen EM Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and c-MET Receptor 1993 Birkauser Verlag Basel, Switzerland 131 165
6. Di Renzo M Narsimhan RP Olivero M Expression of the Met/HGF receptor in normal and neoplastic human tissues Oncogene 6 1991 1997 2003
7. Kan M Zhang G Zarnegar R Hepatocyte growth factor, hepatopoietin A stimulates the growth of rat-kidney proximal epithelial cells (rpte), rat nonparenchymal liver cells, human melanoma cells and mouse keratinocytes, and stimulates anchorage independent growth of SV40-transformed rpte Biochem Biophys Res Commun 174 1991 331 337
8. Prat M Narsimhan RP Crepaldi T The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors Int J Cancer 49 1991 323 328
9. Nakamura S Gohda E Matsunaga T Production of hepatocyte growth factor by human haematopoietic cell lines Cytokine 6 1994 285 294
10. Rygaard K Nakamura T Spang-Thomsen M Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts Br J Cancer 67 1993 37 46
11. Ebert M Yokoyama M Friess H Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer Cancer Res 54 1994 5775 5778
12. Kurimoto S Moriyama N Horie S Co-expression of hepatocyte growth factor and its receptor in human prostate cancer Histochem J 30 1998 27 32
13. Rong S Jeffers M Resau JH Met expression and sarcoma tumorigenicity Cancer Res 53 1993 5355 5360
14. Ferracini R Di Renzo M Scotlandi K The Met/HGF receptor is overexpressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit Oncogene 10 1995 739 749
15. Rao UNM Sonmez-Alpan E Michalopoulos GK Hepatocyte growth factor and c-MET in benign and malignant peripheral nerve sheath tumors Hum Pathol 28 1997 1066 1070
16. Fukuda T Ichimura E Shinozaki T Coexpression of HGF and c-MET/HGF receptor in human bone and soft tissue tumors Pathol Int 48 1998 757 762
17. Kuhnen C Tolnay E Steinau HU Expression of c-met receptor and hepatocyte growth factor/scatter factor in synovial sarcoma and epithelioid sarcoma Virchows Arch 432 1998 337 342
18. Tolnay E Kuhnen C Wiethege T Hepatocyte growth factor/scatter factor and its receptor c-MET are overexpressed and associated with an increased microvessel density in malignant pleural mesothelioma J Cancer Res Clin Oncol 124 1998 291 296
19. Enzinger FM Weiss SW Synovial sarcoma, in Soft Tissue Tumors ed 3 1995 Mosby Philadelphia, PA 757 786
20. Clark J Rocques PJ Crew AJ Identification of novel genes, SYT and SSX, involved in the t(X;18) (p11.2;q11.2) translocation found in human synovial sarcoma Nature Genet 7 1994 502 508
21. Crew AJ Clark J Fisher C Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma EMBO J 14 1995 2333 2340
22. de Leeuw B Balemans M Weghuis DO Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2 in t(X; 18) (p11.2;q11.2) positive synovial sarcomas Hum Mol Genet 4 1995 1097 1099
23. Russell WO Cohen J Enzinger F A clinical and pathological staging system for soft tissue sarcomas Cancer 40 1977 1562 1570
24. Oda Y Hashimoto H Tsuneyoshi M Survival in synovial sarcoma: A multivariate study of prognostic factors with special emphasis on the comparison between early death and long-term survival Am J Surg Pathol 17 1993 35 44
25. Cooper CS Park M Blair DG Molecular cloning of a new transforming gene from a chemically transformed human cell line Nature 311 1984 29 33
26. Fligman I Lonardo F Jhanwar SC Molecular diagnosis of synovial sarcoma and characterization of a variant SYT-SSX2 fusion transcript Am J Pathol 147 1995 1592 1599
27. Park M Dean M Kaul K Sequence of MET protooncogene cDNA has features characteristic of the thyosine kinase family of growth-factor receptors Proc Natl Acad Sci U S A 84 1987 6379 6383
28. Miyazawa K Tsubouchi H Naka D Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor Biochem Biophys Res Commun 163 1989 967 973
29. Moriyama T Kataoka H Kawano H Comparative analysis of expression of hepatocyte growth factor and its receptor, c-met, in gliomas, meningiomas and schwannomas in humans Cancer Lett 124 1998 149 155
30. Noguchi S Ueki T Kawauchi S Establishment and characterization of a new synovial sarcoma cell line, SN-SY-1: Special reference to bcl-2 protein and SYT-SSX1 hybrid transcripts Int J Cancer 72 1997 995 1002
31. Siegfried JM Weissfeld LA Singh-Kaw P Association of immunoreactive hepatocyte growth factor with poor survival in resectable non-small cell lung cancer Cancer Res 57 1997 433 439
32. Yamashita J Ogawa M Yamashita S Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer Cancer Res 54 1994 1630 1633
33. Tsarfaty I Resau JH Rulong S The met proto-oncogene receptor and lumen formation Science 257 1992 1258 1261
34. Sreekantaiah C Ladanyi M Rodriguez E Chromosomal aberrations in soft tissue tumors: Relevance to diagnosis, classification, and molecular mechanisms Am J Pathol 144 1994 1121 1124
35. Kawai A Woodruff J Healey JH SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma N Engl J Med 338 1998 153 160
36. Tsuji S Hisaoka M Morimitsu Y Detection of SYT-SSX fusion transcripts in synovial sarcoma by reverse transcription-polymerase chain reaction using archival paraffin-embedded tissue Am J Pathol 153 1998 1807 1812