Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor

Oncogene

Volumn 17, Issue 6, 1998, Pages 741-749

  Santoro, Massimo Mattia ^b   Penengo, Lorenza ^a   Minetto, Marta ^a   Orecchia, Sara ^a   Cilli, Michele ^c   Gaudino, Giovanni ^a,c  

^a UNIVERSITY OF TURIN   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Metastasis; Ron; Signal transduction; Tumorigenesis; Tyrosine kinase

Indexed keywords

MACROPHAGE ACTIVATING FACTOR; PROTEIN TYROSINE KINASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL STRAIN 3T3; FIBROBLAST; MASTOCYTOSIS; METASTASIS POTENTIAL; MOUSE; NEUROFIBROMATOSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA; MUS MUSCULUS;

EID: 0032514371     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201994     Document Type: Article

References (49)

1. Aaronson SA. (1991). Science, 254, 1146-1153.
2. Banu N, Price DJ, London R, Deng B, Mark M, Godowski PJ and Avraham H. (1996). J. Immunol., 156, 2933-2940.
3. Carlson KM, Dou S, Chi D, Scavarda N, Toshima K, Jackson CE, Wells Jr, SA, Goodfellow PJ and Donis-Keller H. (1994). Proc. Natl. Acad. Sci. USA, 91, 1579-1583.
4. Collesi C, Santoro MM, Gaudino G and Comoglio PM. (1996). Mol. Cell. Biol., 16, 5518-5526.
5. Cooper CS, Park M, Blair D, Tainsky MA, Huebner K, Croce CM and Vande Woude GF. (1984). Nature, 311, 29-33.
6. Correll PH, Iwama A, Tondat S, Mayrhofer G, Suda T and Bernstein A. (1997). Genes and function, I, 69-83.
7. Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, Miki T and Gutkind JS. (1995). Cell, 81, 1137-1146.
8. Cowley S, Paterson H, Kemp P and Marshall CJ. (1994). Cell, 77, 841-852.
9. Crespo P, Xu N, Simmonds WF and Gutkind JS. (1994). Nature, 369, 418-420.
10. Del Peso L, Hernandez-Alcoceba R, Embade N, Carnero A, Esteve P, Paje C and Lacal JC. (1997). Oncogene, 15, 3047-3058.
11. Furitsu T, Tsujimura T, Tono T, Ikeda H, Kitayama H, Koshimizu U, Sugahara H, Butterfield JH, Ashman LK, Kanayama Y, et al. (1993). J. Clin. Invest., 92, 1736-1744.
12. Gaudino G, Follenzi A, Naldini L, Collesi C, Santoro MM, Gallo KA, Godowski PJ and Comoglio PM. (1994). EMBO J., 13, 3524-3532.
13. Gaudino G, Avantaggiato V, Follenzi A, Acampora D, Simeone A and Comoglio PM. (1995). Oncogene, 11, 2627-2637.
14. Hanks SK, Quinn AM and Hunter T. (1988). Science, 241, 42-52.
15. Hanks SK and Quinn AM. (1991). Methods Enzymol., 200, 38-62.
16. Hofstra RM, Landsvater RM, Ceccherini I, Stulp RP, Stelwagen T, Luo Y, Pasini B, Hoppener JW, van Amstel HK, Romeo G, et al. (1994). Nature, 367, 375-376.
17. Hubbard SR, Wei L, Ellis L and Hendrickson WA. (1994). Nature, 372, 746-154.
18. Hubbard SR. (1997). EMBO J., 16, 5572-5581.
19. Iwama A, Yamaguchi N and Suda T. (1996). EMBO J., 15, 5866-5875.
20. Jeffers M, Schmidt L, Nakaigawa N, Webb CP, Weirich G, Kishida T, Zbar B and Vande Woude GF. (1997). Proc. Natl. Acad. Sci. USA, 94, 11445-11450.
21. Kitayama H, Kanakura Y, Furitsu T, Tsujimura T, Oritani K, Ikeda H, Sugahara H, Mitsui H, Kanayama Y, Kitamura Y and Matsuzawa Y. (1995). Blood, 85, 790-798.
22. Kurihara N, Iwama A, Tatsumi J, Ikeda K and Suda T. (1996). Blood, 87, 3704-3710.
23. Longley BJ, Tyrrell L, Lu SZ, Ma YS, Langley K, Ding TG, Duffy T, Jacobs P, Tang LH and Modlin I. (1996). Nat. Genet., 12, 312-314.
24. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF and Ahn NG. (1994). Science, 265, 966-970.
25. Medico E, Mongiovi AM, Huff J, Jelinek MA, Follenzi A, Gaudino G, Parsons JT and Comoglio PM. (1996). Mol. Biol. Cell., 7, 495-504.
26. Mohammadi M, Schlessinger J and Hubbard SR. (1996). Cell, 86, 577-587.
27. Muschel RJ, Williams JE, Lowy DR and Liotta LA. (1985). Am. J. Pathol., 121, 1-8.
28. Pandit SD, Donis-Keller H, Iwamoto T, Tomich JM and Pike LJ. (1996). J. Biol. Chem., 271, 5850-5858.
29. Park M, Dean M, Cooper CS, Schmidt M, O'Brien SJ, Blair DG and Vande Woude GF. (1986). Cell, 45, 895-904.
30. Piao X and Bernstein A. (1996). Blood, 87, 3117-3123.
31. Ponzetto C, Bardelli A, Zhen Z, Maina F, dalla Zonca P, Giordano S, Graziani A, Panayotou G and Comoglio PM. (1994). Cell, 77, 261-271.
32. Raitano AB, Halpern JR, Hambuch TM and Sawyers CL. (1995). Proc. Natl. Acad. Sci. USA, 92, 11746-11750.
33. Rodrigues GA and Park M. (1993). Mol. Cell. Biol., 13, 6711-6722.
34. Rodrigues GA and Park M. (1994). Curr. Opin. Genet. Dev., 4, 15-24.
35. Rodrigues GA, Park M and Schlessinger J. (1997). EMBO J., 16, 2634-2645.
36. Rong S, Segal S, Anver M, Resau JH and Vande Woude GF. (1994). Proc. Natl. Acad. Sci. USA, 91, 4731-4735.
37. Santoro M, Carlomagno F, Romano A, Bottaro DP, Dathan NA, Grieco M, Fusco A, Vecchio G, Matoskova B, Kraus MH, Di Fiore PP. (1995). Science, 267, 381-383.
38. Santoro MM, Collesi C, Grisendi S, Gaudino G and Comoglio PM. (1996). Mol. Cell. Biol., 16, 7072-7083.
39. Sanger F, Nicklen S and Coulson AR. (1977). Proc. Natl. Acad. Sci. USA, 74, 5463-5467.
40. Sawyers CL and Denny CT. (1994). Cell, 77, 171-173.
41. Schmidt L, Duh FM, Chen F, Kishida T, Glenn G, Choyke P, Scherer SW, Zhuang Z, Lubensky I, Dean M, Allikmets R, Chidambaram A, Bergerheim UR, Feltis JT, Casadevall C, Zamarron A, Bernues M, Richard S, Lips CJ, Walther MM, Tsui LC, Geil L, Orcutt ML, Stackhouse T, Zbar B, et al. (1997). Nature Genet., 16, 68-73.
42. Smith DR, Vogt PK and Hayman MJ. (1989). Proc. Natl. Acad. Sci. USA, 86, 5291-5295.
43. Songyang Z and Cantley LC. (1995). Trends Biol. Sci., 20, 470-475.
44. Stacey DW, Roudebush M, Day R, Mosser SD, Gibbs JB and Feig LA. (1991). Oncogene, 6, 2297-2304.
45. Tsujimura T, Furitsu T, Morimoto M, Isozaki K, Nomura S, Matsuzawa Y, Kitamura Y and Kanakura Y. (1994). Blood, 83, 2619-2626.
46. Wang MH, Ronsin C, Gesnel MC, Coupey L, Skeel A, Leonard EJ and Breathnach R. (1994). Science, 266, 117-119.
47. Wang J, Auger KR, Jarvis L, Shi Y and Roberts TM. (1995). J. Biol. Chem., 270, 12774-12780.
48. Wang MH, Montero-Julian FA, Dauny I and Leonard E. (1996). Oncogene, 13, 2167-2175.
49. Willet CG, Smith DI, Shridhar V, Wang MH, Emanuel RL, Patidar K, Graham SA, Zhang F, Hatch V, Sugarbaker DJ, Sunday ME. (1997). J. Clin. Invest., 99, 2979-2991.