-
1
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P and Jain RK: Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
2
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia
-
may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D and Keshet E: Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-845, 1992.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
3
-
-
34547124062
-
Hypoxia: A key regulator of angiogenesis in cancer
-
Liao D and Johnson RS: Hypoxia: a key regulator of angiogenesis in cancer. Cancer Metastasis Rev 26: 281-290, 2007.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 281-290
-
-
Liao, D.1
Johnson, R.S.2
-
4
-
-
0036551486
-
Scatter-factor and semaphorin receptors: Cell signalling for invasive growth
-
Trusolino L and Comoglio PM: Scatter-factor and semaphorin receptors: cell signalling for invasive growth. Nat Rev Cancer 2: 289-300, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 289-300
-
-
Trusolino, L.1
Comoglio, P.M.2
-
5
-
-
0024427178
-
Molecular cloning and expression of human hepatocyte growth factor
-
Nakamura T, Nishizawa T, Hagiya M, et al: Molecular cloning and expression of human hepatocyte growth factor. Nature 342: 440-443, 1989.
-
(1989)
Nature
, vol.342
, pp. 440-443
-
-
Nakamura, T.1
Nishizawa, T.2
Hagiya, M.3
-
6
-
-
0030911921
-
Hepatocyte growth factor/scatter factor, a cytokine playing multiple and converse roles
-
Jiang WG and Hiscox S: Hepatocyte growth factor/scatter factor, a cytokine playing multiple and converse roles. Histol Histopathol 12: 537-555, 1997.
-
(1997)
Histol Histopathol
, vol.12
, pp. 537-555
-
-
Jiang, W.G.1
Hiscox, S.2
-
7
-
-
0029985372
-
Emerging multipotent aspects of hepatocyte growth factor
-
Matsumoto K and Nakamura T: Emerging multipotent aspects of hepatocyte growth factor. J Biochem 119: 591-600, 1996.
-
(1996)
J Biochem
, vol.119
, pp. 591-600
-
-
Matsumoto, K.1
Nakamura, T.2
-
8
-
-
0026722243
-
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
-
Bussolino F, Di Renzo MF, Ziche M, et al: Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 119: 629-641, 1992.
-
(1992)
J Cell Biol
, vol.119
, pp. 629-641
-
-
Bussolino, F.1
Di Renzo, M.F.2
Ziche, M.3
-
9
-
-
0025805633
-
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
-
Bottaro DP, Rubin JS, Faletto DL, et al: Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 251: 802-804, 1991.
-
(1991)
Science
, vol.251
, pp. 802-804
-
-
Bottaro, D.P.1
Rubin, J.S.2
Faletto, D.L.3
-
10
-
-
0345601083
-
Met, metastasis, motility and more
-
Birchmeier C, Birchmeier W, Gherardi E and Vande Woude GF: Met, metastasis, motility and more. Nat Rev Mol Cell Biol 4: 915-925, 2003.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Woude, G.F.4
-
11
-
-
44449151030
-
Drug development of MET inhibitors: Targeting oncogene addiction and expedience
-
Comoglio PM, Giordano S and Trusolino L: Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nat Rev Drug Discov 7: 504-516, 2008.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 504-516
-
-
Comoglio, P.M.1
Giordano, S.2
Trusolino, L.3
-
12
-
-
0036006814
-
Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition
-
Maulik G, Shrikhande A, Kijima T, Ma PC, Morrison PT and Salgia R: Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition. Cytokine Growth Factor Rev 13: 41-59, 2002.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 41-59
-
-
Maulik, G.1
Shrikhande, A.2
Kijima, T.3
Ma, P.C.4
Morrison, P.T.5
Salgia, R.6
-
13
-
-
0028946604
-
Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer
-
Di Renzo MF, Olivero M, Giacomini A, et al: Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer. Clin Cancer Res 1: 147-154, 1995.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 147-154
-
-
Di Renzo, M.F.1
Olivero, M.2
Giacomini, A.3
-
14
-
-
0032523074
-
Expression of c-met is a strong independent prognostic factor in breast carcinoma
-
Ghoussoub RA, Dillon DA, D'Aquila T, Rimm EB, Fearon ER and Rimm DL: Expression of c-met is a strong independent prognostic factor in breast carcinoma. Cancer 82: 1513-1520, 1998.
-
(1998)
Cancer
, vol.82
, pp. 1513-1520
-
-
Ghoussoub, R.A.1
Dillon, D.A.2
D'Aquila, T.3
Rimm, E.B.4
Fearon, E.R.5
Rimm, D.L.6
-
15
-
-
30944452172
-
Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma
-
Miller CT, Lin L, Casper AM, et al: Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma. Oncogene 25: 409-418, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 409-418
-
-
Miller, C.T.1
Lin, L.2
Casper, A.M.3
-
16
-
-
0027219258
-
A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor
-
Ponzetto C, Bardelli A, Maina F, et al: A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor. Mol Cell Biol 13: 4600-4608, 1993.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4600-4608
-
-
Ponzetto, C.1
Bardelli, A.2
Maina, F.3
-
17
-
-
0035793091
-
Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways
-
Xiao GH, Jeffers M, Bellacosa A, et al: Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways. Proc Natl Acad Sci USA 98: 247-252, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 247-252
-
-
Xiao, G.H.1
Jeffers, M.2
Bellacosa, A.3
-
18
-
-
0032518375
-
Induction of epithelial tubules by growth factor HGF depends on the STAT pathway
-
Boccaccio C, Andò M, Tamagnone L, et al: Induction of epithelial tubules by growth factor HGF depends on the STAT pathway. Nature 391: 285-288, 1998.
-
(1998)
Nature
, vol.391
, pp. 285-288
-
-
Boccaccio, C.1
Andò, M.2
Tamagnone, L.3
-
19
-
-
0242492548
-
Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells
-
Gerritsen ME, Tomlinson JE, Zlot C, Ziman M and Hwang S: Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells. Br J Pharmacol 140: 595-610, 2003.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 595-610
-
-
Gerritsen, M.E.1
Tomlinson, J.E.2
Zlot, C.3
Ziman, M.4
Hwang, S.5
-
20
-
-
0035421326
-
Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma
-
Dong G, Chen Z, Li ZY, Yeh NT, Bancroft CC and Van Waes C: Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma. Cancer Res 61: 5911-5918, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 5911-5918
-
-
Dong, G.1
Chen, Z.2
Li, Z.Y.3
Yeh, N.T.4
Bancroft, C.C.5
Van Waes, C.6
-
21
-
-
0024522988
-
Smooth muscle releases an epithelial cell scatter factor which binds to heparin
-
Rosen EM, Goldberg ID, Kacinski BM, Buckholz T and Vinter DW: Smooth muscle releases an epithelial cell scatter factor which binds to heparin. In Vitro Cell Dev Biol 25: 163-173, 1989.
-
(1989)
Vitro Cell Dev Biol
, vol.25
, pp. 163-173
-
-
Rosen, E.M.1
Goldberg, I.D.2
Kacinski, B.M.3
Buckholz, T.4
Vinter, D.W.5
-
22
-
-
0023661693
-
Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
-
Stoker M, Gherardi E, Perryman M and Gray J: Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 327: 239-242, 1987.
-
(1987)
Nature
, vol.327
, pp. 239-242
-
-
Stoker, M.1
Gherardi, E.2
Perryman, M.3
Gray, J.4
-
23
-
-
11144358083
-
Reduced HGF expression in subcutaneous CT26 tumor genetically modified to secrete NK4 and its possible relation with antitumor effects
-
Kubota T, Fujiwara H, Amaike H, et al: Reduced HGF expression in subcutaneous CT26 tumor genetically modified to secrete NK4 and its possible relation with antitumor effects. Cancer Sci 95: 321-327, 2004.
-
(2004)
Cancer Sci
, vol.95
, pp. 321-327
-
-
Kubota, T.1
Fujiwara, H.2
Amaike, H.3
-
24
-
-
0034547912
-
HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice
-
Kuba K, Matsumoto K, Date K, Shimura H, Tanaka M and Nakamura T: HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice. Cancer Res 60: 6737-6743, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 6737-6743
-
-
Kuba, K.1
Matsumoto, K.2
Date, K.3
Shimura, H.4
Tanaka, M.5
Nakamura, T.6
-
25
-
-
0031583998
-
HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor
-
Date K, Matsumoto K, Shimura H, Tanaka M and Nakamura T: HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor. FEBS Lett 420: 1-6, 1997.
-
(1997)
FEBS Lett
, vol.420
, pp. 1-6
-
-
Date, K.1
Matsumoto, K.2
Shimura, H.3
Tanaka, M.4
Nakamura, T.5
-
26
-
-
77952812169
-
Committee of the National Cancer Research Institute: Guidelines for the welfare and use of animals in cancer research
-
Workman P, Aboagye EO, Balkwill F, et al: Committee of the National Cancer Research Institute: Guidelines for the welfare and use of animals in cancer research. Br J Cancer 102: 1555 1577, 2010.
-
(2010)
Br J Cancer
, vol.102
, pp. 1555-1577
-
-
Workman, P.1
Aboagye, E.O.2
Balkwill, F.3
-
27
-
-
0034693753
-
Met receptor tyrosine kinase: Enhanced signaling through adapter proteins
-
Furge KA, Zhang YW and Vande Woude GF: Met receptor tyrosine kinase: enhanced signaling through adapter proteins. Oncogene 19: 5582-5589, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 5582-5589
-
-
Furge, K.A.1
Zhang, Y.W.2
Vande Woude, G.F.3
-
28
-
-
67349115229
-
NK4, an HGF antagonist, prevents hematogenous pulmonary metastasis by inhibiting adhesion of CT26 cells to endothelial cells
-
Kubota T, Taiyoh H, Matsumura A, et al: NK4, an HGF antagonist, prevents hematogenous pulmonary metastasis by inhibiting adhesion of CT26 cells to endothelial cells. Clin Exp Metastasis 26: 447-456, 2009.
-
(2009)
Clin Exp Metastasis
, vol.26
, pp. 447-456
-
-
Kubota, T.1
Taiyoh, H.2
Matsumura, A.3
-
29
-
-
0027482251
-
Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract
-
Brown LF, Berse B, Jackman RW, et al: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res 53: 4727-4735, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 4727-4735
-
-
Brown, L.F.1
Berse, B.2
Jackman, R.W.3
-
30
-
-
0035887435
-
Inhibition of growth, invasion, and metastasis of human pancreatic carcinoma cells by NK4 in an orthotopic mouse model
-
Tomioka D, Maehara N, Kuba K, et al: Inhibition of growth, invasion, and metastasis of human pancreatic carcinoma cells by NK4 in an orthotopic mouse model. Cancer Res 61: 7518-7524, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 7518-7524
-
-
Tomioka, D.1
Maehara, N.2
Kuba, K.3
-
31
-
-
0036796020
-
Tumor suppression through angiogenesis inhibition by SUIT-2 pancreatic cancer cells genetically engineered to secrete NK4
-
Saimura M, Nagai E, Mizumoto K, et al: Tumor suppression through angiogenesis inhibition by SUIT-2 pancreatic cancer cells genetically engineered to secrete NK4. Clin Cancer Res 8: 3243-3249, 2002.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3243-3249
-
-
Saimura, M.1
Nagai, E.2
Mizumoto, K.3
-
32
-
-
0032477844
-
Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis
-
Van Belle E, Witzenbichler B, Chen D, et al: Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis. Circulation 97: 381-390, 1998.
-
(1998)
Circulation
, vol.97
, pp. 381-390
-
-
Van Belle, E.1
Witzenbichler, B.2
Chen, D.3
-
33
-
-
0035102323
-
Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo
-
Xin X, Yang S, Ingle G, et al: Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo. Am J Pathol 158: 1111-1120, 2001.
-
(2001)
Am J Pathol
, vol.158
, pp. 1111-1120
-
-
Xin, X.1
Yang, S.2
Ingle, G.3
-
34
-
-
70149095573
-
Cross-talk between the VEGF-A and HGF signalling pathways in endothelial cells
-
Sulpice E, Ding S, Muscatelli-Groux B, et al: Cross-talk between the VEGF-A and HGF signalling pathways in endothelial cells. Biol Cell 101: 525-539, 2009.
-
(2009)
Biol Cell
, vol.101
, pp. 525-539
-
-
Sulpice, E.1
Ding, S.2
Muscatelli-Groux, B.3
-
35
-
-
10644234769
-
The role of hypoxia-induced factors in tumor progression
-
Vaupel P: The role of hypoxia-induced factors in tumor progression. Oncologist 9 (Suppl 5): 10-17, 2004.
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 5
, pp. 10-17
-
-
Vaupel, P.1
-
36
-
-
0037064010
-
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
-
Fukuda R, Hirota K, Fan F, Jung YD, Ellis LM and Semenza GL: Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J Biol Chem 277: 38205-38211, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 38205-38211
-
-
Fukuda, R.1
Hirota, K.2
Fan, F.3
Jung, Y.D.4
Ellis, L.M.5
Semenza, G.L.6
-
37
-
-
0037293542
-
Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: A role for hypoxia-inducible factor-1?
-
Burroughs KD, Oh J, Barrett JC and DiAugustine RP: Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible factor-1? Mol Cancer Res 1: 312-322, 2003.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 312-322
-
-
Burroughs, K.D.1
Oh, J.2
Barrett, J.C.3
Diaugustine, R.P.4
-
38
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
Niu G, Wright KL, Huang M, et al: Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 21: 2000-2008, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
-
39
-
-
0037435011
-
Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway
-
Wei LH, Kuo ML, Chen CA, et al: Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway. Oncogene 22: 1517-1527, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 1517-1527
-
-
Wei, L.H.1
Kuo, M.L.2
Chen, C.A.3
-
40
-
-
51649096739
-
Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells
-
Niu G, Briggs J, Deng J, et al: Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells. Mol Cancer Res 6: 1099-1105, 2008.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1099-1105
-
-
Niu, G.1
Briggs, J.2
Deng, J.3
-
41
-
-
57349168511
-
STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination
-
Jung JE, Kim HS, Lee CS, et al: STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination. Exp Mol Med 40: 479-485, 2008.
-
(2008)
Exp Mol Med
, vol.40
, pp. 479-485
-
-
Jung, J.E.1
Kim, H.S.2
Lee, C.S.3
-
42
-
-
24644457736
-
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
-
Xu Q, Briggs J, Park S, et al: Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene 24: 5552-5560, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 5552-5560
-
-
Xu, Q.1
Briggs, J.2
Park, S.3
|