Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

Journal of Cell Biology

Volumn 155, Issue 4, 2001, Pages 661-673

  Mechtersheimer, Sabine ^a   Gutwein, Paul ^a   Agmon Levin, Nancy ^a   Stoeck, Alexander ^a   Oleszewski, Matthias ^a   Riedle, Svenja ^a   Postina, Rolf ^d   Fahrenholz, Falk ^d   Fogel, Mina ^b   Lemmon, Vance ^c   Altevogt, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b KAPLAN HOSPITAL   (Israel)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

ADAM10; Cell migration; Integrins; L1; Shedding

Indexed keywords

ALPHAVBETA5 INTEGRIN; ARGINYL-GLYCYL-ASPARTIC ACID; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; BACE1 PROTEIN, MOUSE; CALGRANULIN; INTEGRIN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; NERVE CELL ADHESION MOLECULE; OLIGOPEPTIDE; PEPTIDE FRAGMENT; PLASMIN; PROTEINASE; SECRETASE; VITRONECTIN RECEPTOR;

ANIMAL; ANTAGONISTS AND INHIBITORS; AUTOCRINE EFFECT; BINDING SITE; BRAIN; CELL MEMBRANE; CELL MOTION; CHO CELL LINE; CYTOPLASM; EMBRYOLOGY; GENE EXPRESSION; GENETICS; HAMSTER; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; PHYSIOLOGY; SOLUBILITY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL CULTURE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIBODIES, MONOCLONAL; ASPARTIC ACID ENDOPEPTIDASES; AUTOCRINE COMMUNICATION; BINDING SITES; BIOLOGICAL TRANSPORT; BRAIN; CELL MEMBRANE; CELL MOVEMENT; CHO CELLS; CRICETINAE; CYTOPLASM; ENDOPEPTIDASES; FIBRINOLYSIN; GENE EXPRESSION; HUMANS; INTEGRINS; LEUKOCYTE L1 ANTIGEN COMPLEX; MEMBRANE GLYCOPROTEINS; MICE; NEURAL CELL ADHESION MOLECULES; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RECEPTORS, VITRONECTIN; SOLUBILITY; TUMOR CELLS, CULTURED;

EID: 84924172827     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.200101099     Document Type: Article

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