Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin αvβ3

Journal of Cell Biology

Volumn 132, Issue 3, 1996, Pages 475-485

  Montgomery, Anthony M P ^a   Becker, Jurgen C ^a   Siu, Chi Hung ^b   Lemmon, Vance P ^c   Cheresh, David A ^a   Pancook, James D ^a   Zhao, Xiaoning ^b   Reisfeld, Ralph A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CALCIUM; EGTAZIC ACID; HYBRID PROTEIN; IMMUNOGLOBULIN; INTEGRIN; LIGAND; MONOCLONAL ANTIBODY; NERVE CELL ADHESION MOLECULE; POLYCLONAL ANTIBODY;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MELANOMA CELL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIGENS, SURFACE; BASE SEQUENCE; BINDING SITES; CELL ADHESION; CELL LINE; CELL MOVEMENT; DNA PRIMERS; HUMANS; KINETICS; LEUKOCYTE L1 ANTIGEN COMPLEX; LIGANDS; MELANOMA; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEURAL CELL ADHESION MOLECULES; OLIGOPEPTIDES; POLYMERASE CHAIN REACTION; RATS; RECEPTORS, VITRONECTIN; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED;

EID: 0030065691     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.132.3.475     Document Type: Article

References (52)

1. Ager, A., and M. L. Humphries. 1991. Integrin alpha 4 beta 1: its structure, ligand binding specificity and role in lymphocyte-endothelial cell interactions Chem. Immunol. 50:50-74.
2. Albelda, S. M. 1993. Role of integrins and other cell adhesion molecules in tumor progression and metastasis. Lab. Invest. 68:4-17.
3. Albelda, S M., S. A. Mette, D. E. Elder, R. Stewart, L. Damjanovich, M. Herlyn, and C. A. Buck. 1991. Integrin distribution in malignant melanoma: association of the β3 subunit with tumor progression. Cancer Res. 50:6757-6764.
4. Bock, E. C., C. Richter-Landsberg, A. Faissner, and M. Schachner. 1985. Demonstration of immunochemical identity between the nerve growth factor-inducible large external (NILE) glycoprotein and the cell adhesion molecule L1. EMBO (Eur. Mol Biol Organ.) J. 4:2765-2768.
5. 3 antagonists promote tumor regression by inducing apoptosis of angiogenic vessels. Cell. 79:1-20.
6. Cheresh, D. A. 1992. Structural and biological properties of integrin mediated cell adhesion. Lab. Immunol. 12:217-236
7. Cheresh, D. A., and R. C. Spiro. 1987. Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen and von Willebrand factor. J. Biol. Chem. 262:17703-17711.
8. Clyman, R. J., F. Mauray, and R. H. Kramer. 1992. β1 and β2 integrins have different roles in the adhesion and migration of vascular smooth muscle cells on extracellular matrix. Exp. Cell Res. 200:272-284.
9. Felding-Habermann, B., B. M. Mueller, C. A. Romerdahl, and D. A. Cheresh. 1992. Involvement of integrin αv-gene expression in human melanoma tumorigenicity. J. Clin Invest. 89:2018-2022.
10. Felsenfeld, D. P., M. A. Hynes, K. M. Skoler, A. J Furley, and T. M Jessell 1994. TAG-1 can mediate homophilic binding, but neurite outgrowth on TAG-1 requires an L1-like molecule and β1 integrins. Neuron. 12:675-690
11. Friedlander, D. R., P. Milev, L. Karthikeyan, R. K. Margolis, R. U. Margolis, and M. Grumet. 1994. The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth. J. Cell Biol. 125:669-680.
12. Grumet, M., S. Hoffman, C. M. Chuong, and G. M. Edelman. 1984. Polypeptide components and binding functions of neuron-glia cell adhesion molecules. Proc. Natl. Acad. Sci. USA. 81:7989-7993.
13. Grumet, M., D. R. Friedlander, and G. M. Edelman. 1993a. Evidence for the binding of Ng-CAM to laminin Cell Adhes Commun. 1:177-190.
14. Grumet, M., A. Flaccus, and R. U. Margolis. 1993b. Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules. J. Cell Biol. 120:815-824.
15. Hemsley, A., N. Arnheim, M. D. Toney, G. Cortopassi, and D J. Galas. 1989. A simple method for the site directed mutagenesis using the polymerase chain reaction Nucleic Acid Res. 17:6545-6551.
16. Hlavia, M. L , and V. Lemmon. 1991. Molecular and functional testing of human L1CAM: an interspecies comparison. Genomics. 11 416-423.
17. Hubbe, M., A Kowitz, V. Schirrmacher, M. Schachner, and P. Altevogt. 1993 L1 adhesion molecule on mouse leukocytes: regulation and involvement in endothelial cell binding Eur J. Immunol. 23:2927-2931
18. Kobayashi, M., M. Miura, H Asou, and K. Uyemura. 1991 Molecular cloning of cell adhesion molecule L1 from human nervous tissue: a comparison of the primary sequences of L1 molecules of different origin. Biochem Biophys Acta. 1090:238-240.
19. Kobayashi, M., T. Mizuki, A. Wada, and F. Izumi. 1992. Cell-cell contact modulates expression of cell adhesion molecule L1 in PC12 cells. Neuroscience 49 437-441
20. Kowitz, A., G. Kadmon, M Eckert, V. Schirrmacher, M. Schachner, and P Altevogt. 1992 Expression and function of the neural cell adhesion molecule L1 in mouse leukocytes. Eur. J. Immunol. 22:1199-1205.
21. Kuhn, T B., E T. Stoeckli, M. A. Condrau, F G Rathjen, and P Sonderegger. 1991. Neurite outgrowth on immobilized Axonin-1 is mediated by a heterophilic interaction with L1(G4). J Cell Biol. 115:1113-1126.
22. Kujat, R., F. Miragall, D Krause, R. Dermietzel, and K H. Wrobel 1995 Immunolocalization of the neural cell adhesion molecule L1 in non-proliferating epithelial cells of the male urogenital tract. Histochem. Cell Biol. 103: 311-321.
23. Lagenaur, C., and V. Lemmon. 1987. An L-1-like molecule, the 8D9 Antigen, is a potent substrate for neurite extension. Proc. Natl. Acad. Sci. USA 84: 7753-7757.
24. Leavesley, D. I., G. D Ferguson, E. A. Wayner, and D. A Cheresh. 1992. Requirement of the integrin β3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen J. Cell Biol. 117:1101-1107.
25. Lemmon, V., and S. McLoon 1986. The appearence of an L1-like molecule in the chick visual pathway J Neuroscience. 6:2987-2994.
26. Lemmon, V., K. L. Farr, and C. Lagenaur. 1989. L-1-mediated axon outgrowth occurs via a homophilic binding mechanism. Neuron. 2:1597-1603.
27. Linnemann, D., A. Raz, and E Bock 1989. Differential expression of cell adhesion molecules in variants of the K1735 melanoma cells differing in metastatic capacity. Int. J. Cancer. 43:709-712.
28. Lindner, J., F. G. Rathjen, and M. Schachner. 1983 L-1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum. Nature (Lond.) 305:427-430.
29. Martini, R., and M Schachner. 1986. Immunoelectron microscopic localization of neural cell adhesion molecules (L-1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve. J. Cell Biol 103:2439-2448
30. Miura, M., M. Kobayashi, H. Asou, and K. Uyemura. 1991 Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1. FEBS Lett. 289: 91-95.
31. Miura, M , M. Kobayashi, and K. Uyemura. 1992. Fuctional expression of a full-lenth cDNA coding for rat neural cell adhesion and migration of cerebellar neurons J. Biol Chem. 267:10752-10758
32. Moolenaar, C. E. C., C. Pieneman, F. S. Walsh, W. J. Mooi, and R. J. A. M. Michalides. 1992. Alternative splicing of neural cell adhesion molecule mRNA in human small cell lung cancer cell line H69. Int. J. Cancer 51:238-243
33. Moos, M , R. Tacke, H Scherer, D Peplow, K. Früh, and M. Schachner. 1988 Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin. Nature (Lond.). 334:701-703.
34. 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci USA 91:8856-8860.
35. Mujoo, K , R. C. Spiro, and R. A. Reisfeld. 1986. Characterization of a unique glycoprotein antigen expressed on the surface of human neuroblastoma cells. J. Biol. Chem. 261:10299-10309.
36. 3 integrin involved in adhesion of leukocytes to endothelium. J. Cell Biol 130:451-460.
37. Poltorak, M., K. Shimoda, and W. J. Freed. 1990 Cell adhesion molecules (CAMs) in adrenal medulla in situ and in vitro: enhancement of chromaffin cell L1/Ng-CAM expression by NGF. Exp. Neurology. 110:52-72.
38. Rader, C., E. T. Stoeckli, U. Ziegler, T. Osterwalder, B. Kunz, and P Sonderegger. 1993. Cell-cell adhesion by homophilic interaction of the neuronal recognition molecule axonin-1. Eur. J. Biochem 215:133-141
39. Rao, Y., X. F. Wu, P. Yip, J. Gariepy, and C. H. Siu. 1993. Structural characterization of a homophilic binding site in the neural cell adhesion molecule. J. Biol. Chem. 268:20630-20638.
40. Rathjen, F G., and M. Schachner. 1984. Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion. EMBO (Eur. Mol Biol. Organ) J 3:1-10.
41. Reid, R. A., and J. J. Hemperly. 1992 Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA. J. Mol. Neurosci 3:127-135.
42. Sadoul, K., R. Sadoul, A. Faissner, and M. Schachner. 1988. Biochemical characterization of different molecular forms of the neural cell adhesion molecule L1. J. Neurochem. 50:510-521.
43. Sanders, L C., B. Felding-Habermann, B. M. Mueller, and D. A. Cheresh. 1992. Role of αv integrins and vitronectin in human melanoma cell growth. Cold Spring Harbor Symp. Quant Biol. LVII:233-240b.
44. Sonderegger, P. R . and F. G Rathjen. 1992. Regulation of axonal growth in the vertebrate nervous system by interactions between glycoproteins belonging to two subgroups of the immunoglobulin superfamily. J. Cell Biol. 119:1387-1394.
45. Staunton, D. E., M. L. Dustin, H. P. Erickson, and T. A Springer. 1990. The arrangement of the immunoglobulm-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus. Cell. 61:243-254.
46. Thor, G., R. Probstmeier, and M. Schachner. 1987. Characterization of the cell adhesion molecules L1, N-CAM and J1 in the mouse intestine. EMBO (Eur. Mol. Biol. Organ.) J. 6:2581-2586.
47. Traunecker, A., A. Lanzavecchia, and K. Karjalainen. 1991. Bispecific single chain molecules (Janusins) target cytotoxic lymphocytes on HIV infected cells. EMBO (Eur. Mol. Biol Organ) J. 10-3655-3659.
48. Wang, J.-H., R. B Pepinsky, T. Stehle, J.-H. Liu, M. Karpusas, B. Browning, and L. Osborn. 1995. The crystal structure of an N-termmal two domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-α4 integrin interaction. Proc Natl. Acad. Sci. USA 92:5714-5718.
49. 5 contribute to cell attachment to vitronectin but diferentially distribute on the cell surface. J. Cell Biol 113:919-929.
50. Williams, A. F., and A. N. Barclay 1988. The immunoglobulin superfamily-domains for cell surface recognition. Annu. Rev. Immunol. 6:381-405.
51. Wolff, J. M., R. Frank, K. Mujoo, R. C. Spiro, R. A. Reisfeld, and F. G. Rathjen. 1988. A human glycoprotein related to the mouse cell adhesion molecule L1. J. Biol. Chem. 263:11943-11947.
52. Zhao, X , and C.-H. Siu, 1995. Co-localization of the homophilic binding site and the neuritogenic activity of the cell adhesion molecule L1 to the second Ig-like domain J Biol. Chem In press.