Neural cell adhesion molecule L1: Signaling pathways and growth cone motility

Journal of Neuroscience Research

Volumn 49, Issue 1, 1997, Pages 1-8

  Kamiguchi, Hiroyuki ^a   Lemmon, Vance ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Immunoglobulin superfamily; Neurite outgrowth; Signal transduction

Indexed keywords

NERVE CELL ADHESION MOLECULE;

CELL ADHESION; CELL COMMUNICATION; CELL MOTILITY; GROWTH CONE; MOLECULAR INTERACTION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; SECOND MESSENGER; SHORT SURVEY;

ANIMALS; CELL ADHESION; CELL ADHESION MOLECULES, NEURONAL; CELL MOVEMENT; CYTOSKELETON; DIMERIZATION; HUMANS; LEUKOCYTE L1 ANTIGEN COMPLEX; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MODELS, NEUROLOGICAL; MULTIGENE FAMILY; NEURITES; SIGNAL TRANSDUCTION;

EID: 0030812083     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19970701)49:1<1::AID-JNR1>3.0.CO;2-H     Document Type: Short Survey

References (81)

1. Appleby MW, Gross JA, Cooke MA, Levin SD, Quian X, Perlmutter RM (1992): Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70:751-763.
2. Atashi JR, Klinz SG, Ingraham CA, Matten WT, Schachner M, Maness PF (1992): Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes. Neuron 8:831-842.
3. Bastmeyer M, Ott H, Leppert CA, Stuermer CAO (1995): Fish E587 glycoprotein, a member of the L1 family of cell adhesion molecules, participates in axonal fasciculation and the age-related order of ganglion cell axons in the goldfish retina. J Cell Biol 130:969-976.
4. Brieher WM, Yap AS, Gumbiner BM (1996): Lateral dimerization is required for the homophilic binding activity of C-cadherin. J Cell Biol 135:487-496.
5. Brümmendorf T, Rathjen FG (1994): Cell adhesion molecules 1: Immunoglobulin superfamily. Protein Profile 1:963-1108.
6. Brümmendorf T, Wolff JM, Frank R, Rathjen FG (1989): Neural cell recognition molecule F11: Homology with fibronectin type III and immunoglobulin type C domains. Neuron 2:1351-1361.
7. Brümmendorf T, Hubert M, Treubert U, Leuschner R, Tárnok A, Rathjen FG (1993): The axonal recognition molecule F11 is a multifunctional protein: specific domains mediate interactions with Ng-CAM and restrictin. Neuron 10:711-727.
8. Buchstaller A, Kunz S, Berger P, Kunz B, Ziegler U, Rader C, Sonderegger P (1996): Cell adhesion molecules NgCAM and axonin-1 form heterodimers in the neuronal membrane and cooperate in neunte outgrowth promotion. J Cell Biol 135:1593-1607.
9. Burden-Gulley SM, Lemmon V (1996): L1/8D9, N-cadherin and laminin induce distinct distribution patterns of cytoskeletal elements in growth cones. Cell Motil Cytoskeleton 35:1-23.
10. Burden-Gulley SM, Payne HR, Lemmon V (1995): Growth cones are actively influenced by substrate-bound adhesion molecules. J Neurosci 15:4370-4381.
11. Burns FR, Vonkannen S, Guy L, Raper JA, Kamholz J, Chang S (1991): DM-GRASP, a novel immunoglobulin superfamily axonal surface protein that supports neurite extension. Neuron 7:209-220.
12. Cervello M, Lemmon V, Landreth G, Rutishauser U (1991): Phosphorylation-dependent regulation of axon fasciculation. Proc Natl Acad Sci USA 88:10548-10552.
13. Cervello M, Matranga V, Durbec P, Rougon G, Gomez S (1996): The GPI-anchored adhesion molecule F3 induces tyrosine phosphorylation: Involvement of the FNIII repeats. J Cell Sci 109:699-704.
14. Dahlin-Huppe K, Berglund EO, Ranscht B, Stallcup WB (1997): Mutational analysis of the L1 neuronal cell adhesion molecule identifies membrane-proximal amino acids of the cytoplasmic domain that are required for cytoskeletal anchorage. Mol Cell Neurosci (in press).
15. Davis JQ, Bennett V (1994): Ankyrin binding activity shared by the neurofascin/L 1/NrCAM family of nervous system cell adhesion molecules. J Biol Chem 269:27163-27166.
16. Davis JQ, Mc Laughlin T, Bennett V (1993): Ankyrin-binding proteins related to nervous system cell adhesion molecules - candidates to provide transmembrane and intercellular connections in adult brain. J Cell Biol 121:121-133.
17. DeBernardo AP, Chang S (1996): Heterophilic interactions of DM-GRASP: GRASP-NgCAM interactions involved in neurite extension. J Cell Biol 133:657-666.
18. Diamond MS, Springer TA (1994): The dynamic regulation of integrin adhesiveness. Curr Biol 4:506-517.
19. DiMilla PA, Barbee K, Lauffenburger DA (1991): Mathematical model for the effects of adhesion and mechanics on cell migration speed. Biophys J 60:15-37.
20. Doherty P, Walsh F (1996): CAM-FGF receptor interactions: a model for axonal growth. Mol Cell Neurosci 8:99-111.
21. Doherty P, Williams E, Walsh FS (1995): A soluble chimeric form of the L1 glycoprotein stimulates neurite outgrowth. Neuron 14:57-66.
22. Dubreuil RR, MacVicar G, Dissanayake S, Liu C, Homer D, Hortsch M (1996): Neuroglian-mediated cell adhesion induces assembly of the membrane skeleton at cell contact sites. J Cell Biol 133:647-655.
23. Felsenfeld DP, Choquet D, Sheetz MP (1996): Ligand binding regulates the directed movement of β1 integrins on fibroblasts. Nature 383:438-440.
24. Friesel RE, Maciag T (1995): Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction. FASEB J 9:919-925.
25. Furley AJ, Morton SB, Manalo D, Karagogeos D, Dodd J, Jessell TM (1990): The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity. Cell 61:157-170.
26. Carver TD, Davis JQ, Ren Q, Bennett V (1996): Association of ankyrin with the neuronal cell adhesion molecule neurofascin: regulation by both tyrosine phosphorylation and alternative exon usage. Mol Biol Cell [Suppl] 7:384a.
27. Gennarini G, Cibelli C, Rougon G, Mattei MG, Goridis C (1989): The mouse neuronal cell surface protein F3: a phosphatidylinositolanchored member of the immunoglobulin superfamily related to chicken contactin. J Cell Biol 109:775-788.
28. Girault J-A, Hemmings HC, Zorn SH, Gustafson EL, Greengard P (1990): Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II. J Neurochem 55:1772-1783.
29. Grumet M, Edelman GM (1988): Neuron-glia cell adhesion molecule interacts with neurons and astroglia via different binding mechanisms. J Cell Biol 106:487-503.
30. Gundersen RW (1987): Response of sensory neuntes and growth cones to patterned substrata of laminin and fibronectin in vitro. Dev Biol 121:423-431.
31. Hall H, Walsh FS, Doherty P (1996): Review: a role for the FGF receptor in the axonal growth response stimulated by cell adhesion molecules? Cell Adhes Commun 3:441-450.
32. Hlavin ML, Lemmon V (1991): Molecular structure and functional testing of human L1CAM: an interspecies comparison. Genomics 11:416-423.
33. Hortsch M (1996): The L1 family of neural cell adhesion molecules: old proteins performing new tricks. Neuron 17:587-593.
34. Hortsch M, Wang Y, Marikar Y, Bieber AJ (1995): The cytoplasmic domain of the drosophila cell adhesion molecule neuroglian is not essential for its homophilic adhesive properties in S2 cells. J Biol Chem 270:18809-18817.
35. Ignelzi MA, Miller DR, Soriano P, Maness PF (1994): Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1. Neuron 12:873-884.
36. Kuhn TB, Stoeckli ET, Condrau MA, Rathjen FG, Sonderegger P (1991): Neurite outgrowth on immobilized axonin-1 is mediated by a heterophilic interaction with L1 (G4). J Cell Biol 115:1113-1126.
37. Kuhn TB, Schmidt MF, Kater SB (1995): Laminin and fibronectin guideposts signal sustained but opposite effects to passing growth cones. Neuron 14:275-285.
38. Kunz S, Ziegler U, Kunz B, Sonderegger P (1996): Intracellular signaling is changed after clustering of the neural cell adhesion molecules axonin-1 and NgCAM during neurite fasciculation. J Cell Biol 135:253-267.
39. Lauffenburger DA, Horwitz AF (1996): Cell migration: a physically integrated molecular process. Cell 84:359-369.
40. 2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature 377:75-79.
41. Lemmon V, Farr K, Lagenaur C (1989): L1-mediated axon outgrowth occurs via a homophilic binding mechanism. Neuron 2:1597-1603.
42. Lemmon V, Burden SM, Payne HR, Elmslie GJ, Hlavin ML (1992): Neurite growth on different substrates: permissive versus instructive influences and the role of adhesive strength. J Neurosci 12:818-826.
43. Lin CH, Forscher P (1995): Growth cone advance is inversely proportional to retrograde f-actin flow. Neuron 14:763-771.
44. Lindsay RM, Wiegand SJ, Altar CA, DiStefano PS (1994): Neurotrophic factors: from molecule to man. Trends Neurosci 17:182-190.
45. Mason IJ (1994): The ins and outs of fibroblast growth factors. Cell 78:547-552.
46. Matsuyoshi N, Hamaguchi M, Taniguchi S, Nagafuchi A, Tsukita S, Takeichi M (1992): Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J Cell Biol 118:703-714.
47. Mitchison TJ, Cramer LP (1996): Actin-based cell motility and cell locomotion. Cell 84:371-379.
48. Miura M, Kobayashi M, Asou H, Uyemura K (1991): Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1 - two L1 isoforms in the cytoplasmic region are produced by differential splicing. FEBS Lett 289:91-95.
49. Montgomery AMP, Becker JC, Siu CH, Lemmon VP, Cheresh DA, Pancook JD, Zhao X, Reisfeld RA (1996): Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin αVβ3. J Cell Biol 132:475-485.
50. Moos M, Tacke R, Scherer H, Teplow D, Fruh K, Schachner M (1988): Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin. Nature 334:701-703.
51. Otsuka AJ, Franco R, Yang B, Shim KH, Tang LZ, Zhang YY, Boontrakulpoontawee P, Jeyaprakash A, Hedgecock E, Wheaton VI, Sobery A (1995): An ankyrin-related gene (unc-44) is necessary for proper axonal guidance im Caenorhabditis elegans. J Cell Biol 129:1081-1092.
52. Palecek SP, Schmidt CE, Lauffenburger DA, Horwitz AF (1996): Integrin dynamics on the tail region of migrating fibroblasts. J Cell Sci 109:941-952.
53. Reth M (1992): Antigen receptors on B lymphocytes. Annu Rev Immunol 10:97-121.
54. Rivas RJ, Burmeister DW, Goldberg DJ (1992): Rapid Effects of laminin on the growth cone. Neuron 8:107-115.
55. Ruppert M, Aigner S, Hubbe M, Yagita H, Altevogt P (1995): The L1 adhesion molecule is a cellular ligand for VLA-5. J Cell Biol 131:1881-1891.
56. Sadoul R, Kirchhoff F, Schachner M (1989): A protein kinase activity is associated with and specifically phosphorylates the neural cell adhesion molecule L1. J Neurochem 53:1471-1478.
57. Saffell JL, Williams EJ, Mason IJ, Walsh FS, Doherty P (1997): Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs. Neuron 18:231-242.
58. Salton SRJ, Shelanski ML, Greene LA (1983): Biochemical properties of the nerve growth factor inducible large external (NILE) glycoprotein. J Neurosci 3:2420-2430.
59. Schmidt CE, Horwitz AF, Lauffenburger DA, Sheetz MP (1993): Integrin-cytoskeletal interactions in migrating fibroblasts are dynamic, asymetric, and regulated. J Cell Biol 123:977-991.
60. Schmidt CE, Dai JW, Lauffenburger DA, Sheetz MP, Horwitz AF (1995): Integrin-cytoskeletal interactions in neuronal growth cones. J Neurosci 15:3400-3407.
61. Schuch U, Lohse MJ, Schachner M (1989): Neural cell adhesion molecules influence second messenger systems. Neuron 3:13-20.
62. Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grübel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA (1995): Structural basis of cell-cell adhesion by cadherins. Nature 374:327-337.
63. Skubitz A, Letourneau PC, Wayner E, Furcht LT (1991): Synthetic peptides from the carboxy-terminal globular domain of the a chain of laminin - their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the β1 integrin subunit. J Cell Biol 115:1137-1148.
64. Stein PL, Lee HM, Rich S, Soriano P (1992): p59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70:741-750.
65. Stoeckli ET, Ziegler U, Bleiker AJ, Groscurth P, Sonderegger P (1996): Clustering and functional cooperation of Ng-CAM and axonin-1 in the substrate contact area of growth cones. Dev Biol 177:15-29.
66. Takeda Y, Asou H, Murakami Y, Miura M, Kobayashi M, Uyemura K (1996): A noneuronal isoform of cell adhesion molecule L1: tissue-specific expression and functional analysis. J Neurochem 66:2338-2349.
67. Thomas SM, Soriano P, Imamoto A (1995): Specific and redundant roles of src and fyn in organizing the cytoskeleton. Nature 376:267-271.
68. Tongiorgi E, Bernhardt RR, Schachner M (1995): Zebrafish neurons express two L1-related molecules during early axonogenesis. J Neurosci Res 42:547-561.
69. Trivier E, De Cesare D, Jacquot S, Pannetier S, Xackai E, Young I, Mandel JL, Sassone-Corsi P, Hanauer A (1996): Mutations in the kinase Rsk-2 associate with Coffin-Lowry sundrome. Nature 384:567-570.
70. Ulloa L, Diaznido J, Avila J (1993): Depletion of casein kinase-11 by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells. EMBO J 12:1633-1640.
71. von Bohlen und Halbach F, Taylor J, Schachner M (1992): Cell type-specific effects of the neural adhesion molecules L1 and N-CAM on diverse second messenger systems. Eur J Neurosci 4:896-909.
72. Williams EJ, Doherty P, Turner G, Reid RA, Hemperly JJ, Walsh FS (1992): Calcium influx into neurons can solely account for cell contact-dependent neurite outgrowth stimulated by transfected L1. J Cell Biol 119:883-892.
73. Wong EV, Cheng G, Payne HR, Lemmon V (1995a): The cytoplasmic domain of the cell adhesion molecule L1 is not required for homophilic adhesion. Neurosci Lett 200:155-158.
74. Wong EV, Kenwrick S, Willems P, Lemmon V (1995b): Mutations in the cell adhesion molecule L1 cause mental retardation. Trends Neurosci 18:168-172.
75. Wong EV, Schaefer AW, Landreth G, Lemmon V (1995c): Casein kinase II phosphorylates the neural cell adhesion molecule L1. J Neurochem 66:779-786.
76. Wong EV, Schaefer A, Landreth G, Lemmon V (1996): Involvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1. J Biol Chem 271:18217-18223.
77. Yamasaki M, Thompson P, Lemmon V (1997): CRASH syndrome: Mutations in the L1 gene correlate with severity of the disease. Neuropediatrics (in press).
78. Zhao X, Siu CH (1995): Colocalization of the homophilic binding site and the neuritogenic activity of the cell adhesion molecule L1 to its second Ig-like domain. J Biol Chem 270:29413-29421.
79. Zhao Y, Bjørbæk C, Moller DE (1996): Regulation and interaction of pp90rsk isotorms with mitogen-activated protein kinases. J Biol Chem 29773-29779.
80. Zisch AH, Stallcup WB, Chong LD, Dahlin-Huppe K, Voshol J, Schachner M, Pasquale EB (1997): Tyrosine phosphorylation of L1 family adhesion molecules: Implication of the Eph kinase Cek5. J Neurosci Res 47:655-665.
81. Zuellig RA, Rader C, Schroeder A, Kalousek MB, Von Bohlen und Halbach F, Osterwalder T, Inan C, Stoeckli ET, Affolter HU, Fritz A, Hafen E, Sonderegger P (1992): The axonally secreted cell adhesion molecule, axonin-1: primary structure, immunoglobulin-like and fibronectin-type-III-like domains and glycosylphosphatidylinositol anchorage. Eur J Biochem 204:453-463.