Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation

Retrovirology

Volumn 11, Issue 1, 2014, Pages

  Landi, Alessia ^a   Vermeire, Jolien ^a   Iannucci, Veronica ^a,b   Vanderstraeten, Hanne ^a   Naessens, Evelien ^a   Bentahir, Mostafa ^a,c   Verhasselt, Bruno ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c Ecole de Sante Publique   (Belgium)

Author keywords

CD4; Endocytosis; HIV 1; Nef; shRNA

Indexed keywords

CD4 ANTIGEN; DYNAMIN III; EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 15; ISOCITRATE DEHYDROGENASE; LENTIVIRUS VECTOR; NEF PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ARTICLE; ATP6AP1 GENE; CD4+ T LYMPHOCYTE; CELL DIVISION; CONTROLLED STUDY; DNM3 GENE; ENDOCYTOSIS; EPS15 GENE; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE LIBRARY; GENE SEQUENCE; GENE SILENCING; HELA CELL LINE; HRBL GENE; HSP90B1 GENE; HUMAN IMMUNODEFICIENCY VIRUS 1; IDH3G GENE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RNA INTERFERENCE; SNX22 GENE; VALIDATION STUDY; VIRUS REPLICATION; BIOSYNTHESIS; CELL LINE; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETIC SCREENING; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; PHYSIOLOGY; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIGENS, CD4; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; DOWN-REGULATION; ENDOCYTOSIS; GENE EXPRESSION REGULATION; GENETIC TESTING; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; RNA, SMALL INTERFERING; VIRUS REPLICATION;

EID: 84924118537     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/s12977-014-0118-4     Document Type: Article

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